ATE241358T1 - Verwendung von cholinesterasehemmer zur behandlung von konzentrationsstörungen - Google Patents

Verwendung von cholinesterasehemmer zur behandlung von konzentrationsstörungen

Info

Publication number
ATE241358T1
ATE241358T1 AT98905121T AT98905121T ATE241358T1 AT E241358 T1 ATE241358 T1 AT E241358T1 AT 98905121 T AT98905121 T AT 98905121T AT 98905121 T AT98905121 T AT 98905121T AT E241358 T1 ATE241358 T1 AT E241358T1
Authority
AT
Austria
Prior art keywords
cholinesterase inhibitors
concentration disorders
treat concentration
treat
disorders
Prior art date
Application number
AT98905121T
Other languages
German (de)
English (en)
Inventor
Sharon L Rogers
Lawrence T Friedhoff
Paul J Tiseo
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Application granted granted Critical
Publication of ATE241358T1 publication Critical patent/ATE241358T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
AT98905121T 1997-03-03 1998-03-03 Verwendung von cholinesterasehemmer zur behandlung von konzentrationsstörungen ATE241358T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3983297P 1997-03-03 1997-03-03
PCT/IB1998/000508 WO1998039000A1 (en) 1997-03-03 1998-03-03 Use of cholinesterase inhibitors to treat disorders of attention

Publications (1)

Publication Number Publication Date
ATE241358T1 true ATE241358T1 (de) 2003-06-15

Family

ID=21907565

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98905121T ATE241358T1 (de) 1997-03-03 1998-03-03 Verwendung von cholinesterasehemmer zur behandlung von konzentrationsstörungen

Country Status (12)

Country Link
US (2) US6455544B1 (enExample)
EP (1) EP0971713B1 (enExample)
JP (1) JP4095676B2 (enExample)
AT (1) ATE241358T1 (enExample)
AU (1) AU743609B2 (enExample)
CA (1) CA2282654C (enExample)
DE (1) DE69815090T2 (enExample)
DK (1) DK0971713T3 (enExample)
ES (1) ES2200313T3 (enExample)
NZ (1) NZ337515A (enExample)
PT (1) PT971713E (enExample)
WO (1) WO1998039000A1 (enExample)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
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PT971713E (pt) * 1997-03-03 2003-09-30 Eisai Co Ltd Utilizacao de inibidores da colinesterase para tratamento de desordens da atencao
GB9716879D0 (en) * 1997-08-08 1997-10-15 Shire Int Licensing Bv Treatment of attention deficit disorders
US6429207B1 (en) 1997-11-21 2002-08-06 Nps Pharmaceuticals, Inc. Metabotropic glutamate receptor antagonists and their use for treating central nervous system diseases
EP1764101A1 (en) * 2000-03-03 2007-03-21 Eisai R&D Management Co., Ltd. Use of a cholinesterase inhibitor for the treatment of dementia and cognitive impairments
US20030153598A1 (en) * 2000-07-25 2003-08-14 Raymond Pratt Methods for treating Parkinson's disease with cholinesterase inhibitors
US20060183776A9 (en) * 2000-03-03 2006-08-17 Eisai Co., Ltd. Liquid dosage formulations of donepezil
DK1311272T3 (da) 2000-03-03 2007-02-26 Eisai R&D Man Co Ltd Hidtil ukendte fremgangsmåder hvor der anvendes cholinesteraseinhibitorer
JP2006516948A (ja) * 2000-11-14 2006-07-13 ニュー リバー ファーマシューティカルズ インコーポレイテッド 硫酸アバカビルを含有する新規な薬剤化合物および同化合物の製造ならびに使用方法
US20070053976A1 (en) * 2002-05-17 2007-03-08 Eisai R & D Management Co., Ltd. Novel combination of drugs as antidepressant
WO2004034963A2 (en) * 2002-05-17 2004-04-29 Eisai Co., Ltd. Methods and compositions using cholinesterase inhibitors
US7589199B2 (en) 2002-06-12 2009-09-15 Chemocentryx, Inc. Substituted piperazines
ES2329356T3 (es) 2002-06-12 2009-11-25 Chemocentryx, Inc. Derivados de piperazina 1-arilo-4-sustituidos utilizados como antagonistas de ccr1 para el tratamiento de enfermedades inflamatorias e inmunitarias.
US20050256130A1 (en) * 2002-06-12 2005-11-17 Chemocentryx, Inc. Substituted piperazines
US7842693B2 (en) 2002-06-12 2010-11-30 Chemocentryx, Inc. Substituted piperazines
US20050232990A1 (en) * 2003-12-31 2005-10-20 Garth Boehm Donepezil formulations
JP4845873B2 (ja) * 2004-03-03 2011-12-28 ケモセントリックス インコーポレーティッド 二環式および架橋した窒素複素環
US7435831B2 (en) * 2004-03-03 2008-10-14 Chemocentryx, Inc. Bicyclic and bridged nitrogen heterocycles
US7795438B2 (en) 2004-04-28 2010-09-14 Eisai R&D Management Co., Ltd Processes for producing 1-benzyl-4-[(5,6-dimethoxy-1indanon)-2-yl]methylpiperidine and hydrochloride
WO2006036936A2 (en) * 2004-09-27 2006-04-06 Bridge Pharma, Inc. The s-isomer of 2-{2-[n-(2-indanyl)-n-phenylamino]ethyl}piperidine and other dermal anesthetic agents
WO2006037047A2 (en) * 2004-09-27 2006-04-06 Bridge Pharma, Inc. The r-isomer of 2-{2-[n-(2-indanyl)-n-phenylamino]ethyl}piperidine and other dermal anesthetic agents
WO2006050359A2 (en) 2004-11-02 2006-05-11 Northwestern University Pyridazine compounds and methods
KR20070097590A (ko) 2005-01-25 2007-10-04 에픽스 델라웨어, 인코포레이티드 치환된 아릴아민 화합물 및 5―ｈｔ6 조절제로서의 이의용도
ME01224B (me) * 2005-04-04 2013-06-20 Eisai R&D Man Co Ltd Jedinjenja dihidropiridina za liječenje neurodegenerativnih bolesti i demencije
AU2006300492B2 (en) * 2005-10-14 2011-08-25 Eisai R & D Management Co., Ltd. Process for producing 1-benzyl-4-[(5,6-dimethoxy-1indanon)-2-yl]methylpiperidine or hydrochloride thereof
EP1960357A2 (en) * 2005-11-14 2008-08-27 Medichem S.A. Synthesis and preparations of intermediates and polymorphs thereof useful for the preparation of donepezil hydrochloride
CA2650711A1 (en) 2006-04-28 2007-11-08 Northwestern University Compositions and treatments using pyridazine compounds and cholinesterase inhibitors
CA2655809C (en) * 2006-07-21 2013-10-01 Bridge Pharma, Inc. Dermal anesthetic compounds
KR101408488B1 (ko) * 2006-12-01 2014-06-17 닛토덴코 가부시키가이샤 도네페질 함유 접착 제제의 경시적인 변색을 억제하는 방법
CN101573115B (zh) * 2006-12-01 2012-06-06 日东电工株式会社 抑制含有多奈哌齐的贴剂着色的方法、及降低多奈哌齐类似物的生成量的方法
JP2010520154A (ja) * 2007-03-05 2010-06-10 エーザイ・アール・アンド・ディー・マネジメント株式会社 神経変性疾患のためのａｍｐａレセプターアンタゴニストおよびｎｍｄａレセプターアンタゴニスト
WO2008139984A1 (en) * 2007-04-26 2008-11-20 Eisai R & D Management Co., Ltd. Cinnamide compounds for dementia
KR100914691B1 (ko) * 2007-08-10 2009-08-28 주식회사유한양행 도네페질 또는 그의 제조용 중간체의 제조방법
EP2279739B2 (en) * 2008-05-30 2018-02-28 Nitto Denko Corporation Donepezil-containing patch preparation and packaging thereof
BRPI0912099A2 (pt) * 2008-05-30 2015-10-06 Eisai R&D Man Co Ltd preparação percutaneamente absorvível
EA037187B1 (ru) 2010-02-09 2021-02-17 Дзе Джонс Хопкинс Юниверсити Способ и композиция для лечения когнитивного расстройства
EP2642998B1 (en) 2010-11-24 2020-09-16 The Trustees of Columbia University in the City of New York A non-retinoid rbp4 antagonist for treatment of age-related macular degeneration and stargardt disease
WO2013166037A1 (en) 2012-05-01 2013-11-07 The Trustees Of Columbia University In The City Of New York Non-retinoid antagonists for treatment of eye disorders
US10154988B2 (en) 2012-11-14 2018-12-18 The Johns Hopkins University Methods and compositions for treating schizophrenia
US9265458B2 (en) 2012-12-04 2016-02-23 Sync-Think, Inc. Application of smooth pursuit cognitive testing paradigms to clinical drug development
US9380976B2 (en) 2013-03-11 2016-07-05 Sync-Think, Inc. Optical neuroinformatics
WO2014151936A1 (en) 2013-03-14 2014-09-25 The Trustees Of Columbia University In The City Of New York Octahydropyrrolopyrroles, their preparation and use
EP2968303B1 (en) 2013-03-14 2018-07-04 The Trustees of Columbia University in the City of New York Octahydrocyclopentapyrroles, their preparation and use
US10273243B2 (en) 2013-03-14 2019-04-30 The Trustees Of Columbia University In The City Of New York 4-phenylpiperidines, their preparation and use
WO2014151959A1 (en) 2013-03-14 2014-09-25 The Trustees Of Columbia University In The City Of New York N-alkyl-2-phenoxyethanamines, their preparation and use
JP6433482B2 (ja) 2013-03-15 2018-12-05 エージンバイオ， インコーポレイテッド 認知機能を改善するための方法および組成物
US10806717B2 (en) 2013-03-15 2020-10-20 The Johns Hopkins University Methods and compositions for improving cognitive function
WO2015168286A1 (en) 2014-04-30 2015-11-05 The Trustees Of Columbia University In The City Of New York Substituted 4-phenylpiperidines, their preparaiton and use
KR101732776B1 (ko) * 2014-10-08 2017-05-04 영남대학교 산학협력단 신규한 인데노 피리디니움 유도체 화합물 및 이의 제조방법
AU2016268096B2 (en) 2015-05-22 2021-04-01 Agenebio, Inc. Extended release pharmaceutical compositions of levetiracetam

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI95572C (fi) * 1987-06-22 1996-02-26 Eisai Co Ltd Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi
US5064858A (en) * 1988-08-17 1991-11-12 Spectrum Pharmaceutical Corporation Protected complex of procaine for the treatment of symptoms from narcotics addiction, tinnitus and Alzheimer's disease
CA2222713C (en) * 1995-07-14 2003-04-22 Andrew John Mcglashan Richards Composition comprising d-threo-methylphenidate and another drug
WO1997046527A1 (en) * 1996-06-07 1997-12-11 Eisai Co., Ltd. Polymorphs of donepezil hydrochloride and process for production
PT971713E (pt) * 1997-03-03 2003-09-30 Eisai Co Ltd Utilizacao de inibidores da colinesterase para tratamento de desordens da atencao

Also Published As

Publication number Publication date
ES2200313T3 (es) 2004-03-01
CA2282654C (en) 2009-02-03
US20030055040A1 (en) 2003-03-20
WO1998039000A1 (en) 1998-09-11
DK0971713T3 (da) 2003-09-22
PT971713E (pt) 2003-09-30
DE69815090D1 (de) 2003-07-03
NZ337515A (en) 2002-07-26
EP0971713A1 (en) 2000-01-19
AU743609B2 (en) 2002-01-31
JP2001515480A (ja) 2001-09-18
DE69815090T2 (de) 2004-02-19
US6455544B1 (en) 2002-09-24
JP4095676B2 (ja) 2008-06-04
CA2282654A1 (en) 1998-09-11
US7105540B2 (en) 2006-09-12
EP0971713B1 (en) 2003-05-28
AU7321598A (en) 1998-09-22

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