ATE360438T1 - Verwendung von inaktives cln2 proenzym zur behandlung von lincl - Google Patents
Verwendung von inaktives cln2 proenzym zur behandlung von linclInfo
- Publication number
- ATE360438T1 ATE360438T1 AT01937337T AT01937337T ATE360438T1 AT E360438 T1 ATE360438 T1 AT E360438T1 AT 01937337 T AT01937337 T AT 01937337T AT 01937337 T AT01937337 T AT 01937337T AT E360438 T1 ATE360438 T1 AT E360438T1
- Authority
- AT
- Austria
- Prior art keywords
- cln2
- lincl
- proenzyme
- inactive
- treat
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/4813—Exopeptidases (3.4.11. to 3.4.19)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/14—Dipeptidyl-peptidases and tripeptidyl-peptidases (3.4.14)
- C12Y304/14009—Tripeptidyl-peptidase I (3.4.14.9)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicinal Preparation (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Compounds Of Unknown Constitution (AREA)
- Saccharide Compounds (AREA)
- Optical Integrated Circuits (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20340700P | 2000-05-11 | 2000-05-11 | |
| US09/852,918 US20020006400A1 (en) | 2000-05-11 | 2001-05-10 | Recombinant human CLN2 protein and methods of its production and use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE360438T1 true ATE360438T1 (de) | 2007-05-15 |
Family
ID=26898578
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01937337T ATE360438T1 (de) | 2000-05-11 | 2001-05-11 | Verwendung von inaktives cln2 proenzym zur behandlung von lincl |
Country Status (10)
| Country | Link |
|---|---|
| US (5) | US20020006400A1 (de) |
| EP (1) | EP1292326B1 (de) |
| JP (1) | JP4843774B2 (de) |
| AT (1) | ATE360438T1 (de) |
| AU (1) | AU2001263085A1 (de) |
| BR (1) | BR0110746A (de) |
| CA (1) | CA2408380C (de) |
| DE (1) | DE60128084T2 (de) |
| MX (1) | MXPA02011162A (de) |
| WO (1) | WO2001085200A2 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7442372B2 (en) | 2003-08-29 | 2008-10-28 | Biomarin Pharmaceutical Inc. | Delivery of therapeutic compounds to the brain and other tissues |
| US9387236B2 (en) * | 2011-06-10 | 2016-07-12 | Prothera Inc. | Pharmaceutical compositions containing protease and methods for the treatment of lysosomal storage diseases |
| ES2432653B1 (es) * | 2012-05-23 | 2015-09-17 | Centro De Investigacion Biomedica En Red De Enfermedades Raras | Un procedimiento y kit para el diagnostico diferencial de una enfermedad que cursa con afectación muscular. |
| TWI752907B (zh) | 2015-05-08 | 2022-01-21 | 美商拜奧馬林製藥公司 | 用於治療cln2疾病之tpp1調配物及方法 |
| LT4021575T (lt) * | 2019-08-29 | 2024-08-12 | Biomarin Pharmaceutical Inc. | Cln2 ligos gydymo būdai pediatriniams pacientams |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6302685B1 (en) * | 1997-09-16 | 2001-10-16 | University Of Medicine And Dentistry Of New Jersey | Human lysosomal protein and methods of its use |
-
2001
- 2001-05-10 US US09/852,918 patent/US20020006400A1/en not_active Abandoned
- 2001-05-11 AU AU2001263085A patent/AU2001263085A1/en not_active Abandoned
- 2001-05-11 JP JP2001581853A patent/JP4843774B2/ja not_active Expired - Lifetime
- 2001-05-11 AT AT01937337T patent/ATE360438T1/de not_active IP Right Cessation
- 2001-05-11 CA CA2408380A patent/CA2408380C/en not_active Expired - Lifetime
- 2001-05-11 EP EP01937337A patent/EP1292326B1/de not_active Expired - Lifetime
- 2001-05-11 DE DE60128084T patent/DE60128084T2/de not_active Expired - Fee Related
- 2001-05-11 WO PCT/US2001/015386 patent/WO2001085200A2/en active IP Right Grant
- 2001-05-11 BR BR0110746-1A patent/BR0110746A/pt not_active Application Discontinuation
- 2001-05-11 MX MXPA02011162A patent/MXPA02011162A/es active IP Right Grant
-
2006
- 2006-08-22 US US11/507,945 patent/US7811559B2/en not_active Expired - Lifetime
-
2010
- 2010-09-13 US US12/881,066 patent/US8029781B2/en not_active Expired - Fee Related
-
2011
- 2011-08-29 US US13/220,572 patent/US8277800B2/en not_active Expired - Lifetime
-
2012
- 2012-08-29 US US13/598,556 patent/US20130273018A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20110014172A1 (en) | 2011-01-20 |
| US8029781B2 (en) | 2011-10-04 |
| US8277800B2 (en) | 2012-10-02 |
| US7811559B2 (en) | 2010-10-12 |
| JP2004519415A (ja) | 2004-07-02 |
| MXPA02011162A (es) | 2003-07-28 |
| US20020006400A1 (en) | 2002-01-17 |
| US20120014935A1 (en) | 2012-01-19 |
| DE60128084D1 (de) | 2007-06-06 |
| DE60128084T2 (de) | 2008-01-03 |
| EP1292326A2 (de) | 2003-03-19 |
| AU2001263085A1 (en) | 2001-11-20 |
| US20090022701A1 (en) | 2009-01-22 |
| EP1292326B1 (de) | 2007-04-25 |
| BR0110746A (pt) | 2003-07-22 |
| US20130273018A1 (en) | 2013-10-17 |
| CA2408380C (en) | 2012-04-17 |
| WO2001085200A2 (en) | 2001-11-15 |
| CA2408380A1 (en) | 2001-11-15 |
| JP4843774B2 (ja) | 2011-12-21 |
| WO2001085200A3 (en) | 2002-04-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |