ATE237578T1 - Verfahren zur herstellung von iodhaltigen kontrastmitteln und zwischenprodukten dafür - Google Patents

Verfahren zur herstellung von iodhaltigen kontrastmitteln und zwischenprodukten dafür

Info

Publication number
ATE237578T1
ATE237578T1 AT98903137T AT98903137T ATE237578T1 AT E237578 T1 ATE237578 T1 AT E237578T1 AT 98903137 T AT98903137 T AT 98903137T AT 98903137 T AT98903137 T AT 98903137T AT E237578 T1 ATE237578 T1 AT E237578T1
Authority
AT
Austria
Prior art keywords
contrast agents
intermediate products
iodine contrast
producing iodine
products therefor
Prior art date
Application number
AT98903137T
Other languages
English (en)
Inventor
David Redick Lane
Janis Vasilevskis
Original Assignee
Amersham Health As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amersham Health As filed Critical Amersham Health As
Application granted granted Critical
Publication of ATE237578T1 publication Critical patent/ATE237578T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00Preparation of carboxylic acid amides
    • C07C231/12Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/04Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reaction of ammonia or amines with olefin oxides or halohydrins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00Preparation of carboxylic acid amides
    • C07C231/14Preparation of carboxylic acid amides by formation of carboxamide groups together with reactions not involving the carboxamide groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/64Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C233/65Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/30Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having the nitrogen atom of the carboxamide group bound to hydrogen atoms or to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/42Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT98903137T 1997-02-07 1998-02-05 Verfahren zur herstellung von iodhaltigen kontrastmitteln und zwischenprodukten dafür ATE237578T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/796,212 US5824821A (en) 1997-02-07 1997-02-07 Process for the preparation of iodinated contrast agents and intermediates therefor
PCT/GB1998/000356 WO1998034905A1 (en) 1997-02-07 1998-02-05 Process for the preparation of iodinated contrast agents and intermediates therefor

Publications (1)

Publication Number Publication Date
ATE237578T1 true ATE237578T1 (de) 2003-05-15

Family

ID=25167625

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98903137T ATE237578T1 (de) 1997-02-07 1998-02-05 Verfahren zur herstellung von iodhaltigen kontrastmitteln und zwischenprodukten dafür

Country Status (15)

Country Link
US (2) US5824821A (de)
EP (1) EP0968173B1 (de)
JP (1) JP2001511173A (de)
CN (1) CN1246844A (de)
AT (1) ATE237578T1 (de)
AU (1) AU5996498A (de)
BR (1) BR9807154A (de)
CA (1) CA2280235A1 (de)
DE (1) DE69813534D1 (de)
HU (1) HUP0000845A3 (de)
IL (1) IL131423A0 (de)
NO (1) NO993806L (de)
PL (1) PL334954A1 (de)
SK (1) SK106799A3 (de)
WO (1) WO1998034905A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100358855B1 (ko) * 2000-02-29 2002-10-31 광주과학기술원 사이클로덱스트린 또는 그 유도체와 조영제의 포접 착체형성 방법
KR100362080B1 (ko) * 2000-03-29 2002-11-23 광주과학기술원 고리 올리고당과 그들의 유도체를 이용한 조영제의 새로운포접 착체
US7300986B2 (en) * 2001-10-12 2007-11-27 Dow3Global Technologies Inc. Polyepoxy compounds having an amide linkage
EP1434771A1 (de) * 2001-10-12 2004-07-07 Dow Global Technologies Inc. Polyepoxyverbindungen mit amidbindung
KR100700701B1 (ko) 2004-10-28 2007-03-28 동국정밀화학(주) 이오딕사놀의 제조방법
US20070148096A1 (en) * 2005-12-15 2007-06-28 Lars-Goran Wistrand Contrast Agents
KR101098553B1 (ko) * 2008-04-30 2011-12-26 주식회사 엘지생명과학 이오프로마이드의 신규한 제조방법
CN101921209B (zh) * 2010-09-09 2013-01-30 江苏省原子医学研究所 5-硝基-n,n′-双(2,3-二羟丙基)-1,3-苯二甲酰胺的制备方法
US9006486B2 (en) * 2013-01-15 2015-04-14 Liebel-Flarsheim Company Llc Synthesis of N1,N3-bis(2,3-dihydroxypropyl)-5-nitroisophthalamide
US11412835B2 (en) 2015-06-08 2022-08-16 Cosmetic Technologies, L.L.C. Automated delivery system of a cosmetic sample

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1548594A (en) * 1976-06-11 1979-07-18 Nyegaard & Co As Triiodoisophthalic acid amides
DE2720968C2 (de) * 1977-05-10 1986-05-07 Kali-Chemie Pharma Gmbh, 3000 Hannover N↓1↓-Acyl-2-hydroxy-1,3-diaminopropane und Arzneimittel
ES469020A1 (es) * 1977-05-10 1979-09-01 Kali Chemie Pharma Gmbh Procedimiento para la preparacion de nuevos 1-acil-2-hidroxi-1,3-diaminopropanos
US4115350A (en) * 1977-07-27 1978-09-19 Allied Chemical Corporation Production of thermally stabilized polyester
DE3014109A1 (de) * 1980-04-12 1981-10-22 Degussa Ag, 6000 Frankfurt Verfahren zur herstellung von 1-aminopropandiol-2,3 (ii)
JPS59191720A (ja) * 1983-04-14 1984-10-30 Unitika Ltd 耐熱性ポリエステルの製造法
JPS6042376A (ja) * 1983-08-18 1985-03-06 Mitsubishi Chem Ind Ltd Ν−(2,3−エポキシプロピレン)スルホンアミド誘導体及びそれを有効成分とする選択性除草剤
US5191119A (en) * 1983-10-20 1993-03-02 Cook Imaging Corp. Process for producing non-ionic radiographic contrast media utilizing N-allylation

Also Published As

Publication number Publication date
BR9807154A (pt) 2000-01-25
NO993806L (no) 1999-09-08
EP0968173A1 (de) 2000-01-05
HUP0000845A2 (hu) 2002-02-28
HUP0000845A3 (en) 2002-07-29
IL131423A0 (en) 2001-01-28
WO1998034905A1 (en) 1998-08-13
JP2001511173A (ja) 2001-08-07
AU5996498A (en) 1998-08-26
DE69813534D1 (de) 2003-05-22
US6153771A (en) 2000-11-28
CN1246844A (zh) 2000-03-08
NO993806D0 (no) 1999-08-06
CA2280235A1 (en) 1998-08-13
PL334954A1 (en) 2000-03-27
US5824821A (en) 1998-10-20
SK106799A3 (en) 2000-01-18
EP0968173B1 (de) 2003-04-16

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