ATE22657T1 - Prostaglandin e1, enthaltende emulsion und verfahren zu ihrer herstellung. - Google Patents
Prostaglandin e1, enthaltende emulsion und verfahren zu ihrer herstellung.Info
- Publication number
- ATE22657T1 ATE22657T1 AT83303427T AT83303427T ATE22657T1 AT E22657 T1 ATE22657 T1 AT E22657T1 AT 83303427 T AT83303427 T AT 83303427T AT 83303427 T AT83303427 T AT 83303427T AT E22657 T1 ATE22657 T1 AT E22657T1
- Authority
- AT
- Austria
- Prior art keywords
- prostaglandin
- preparation
- emulsion containing
- emulsion
- action
- Prior art date
Links
- 239000000839 emulsion Substances 0.000 title abstract 3
- GMVPRGQOIOIIMI-UHFFFAOYSA-N (8R,11R,12R,13E,15S)-11,15-Dihydroxy-9-oxo-13-prostenoic acid Natural products CCCCCC(O)C=CC1C(O)CC(=O)C1CCCCCCC(O)=O GMVPRGQOIOIIMI-UHFFFAOYSA-N 0.000 title abstract 2
- 229960000711 alprostadil Drugs 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- GMVPRGQOIOIIMI-DWKJAMRDSA-N prostaglandin E1 Chemical compound CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(O)=O GMVPRGQOIOIIMI-DWKJAMRDSA-N 0.000 title abstract 2
- XEYBRNLFEZDVAW-UHFFFAOYSA-N prostaglandin E2 Natural products CCCCCC(O)C=CC1C(O)CC(=O)C1CC=CCCCC(O)=O XEYBRNLFEZDVAW-UHFFFAOYSA-N 0.000 title abstract 2
- 230000001684 chronic effect Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000001077 hypotensive effect Effects 0.000 abstract 1
- 238000002347 injection Methods 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
- 239000002960 lipid emulsion Substances 0.000 abstract 1
- 230000000304 vasodilatating effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Dispersion Chemistry (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP57104814A JPS58222014A (ja) | 1982-06-18 | 1982-06-18 | プロスタグランジンe↓1脂肪乳剤 |
EP83303427A EP0097481B1 (de) | 1982-06-18 | 1983-06-14 | Prostaglandin E1, enthaltende Emulsion und Verfahren zu ihrer Herstellung |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE22657T1 true ATE22657T1 (de) | 1986-10-15 |
Family
ID=14390874
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT83303427T ATE22657T1 (de) | 1982-06-18 | 1983-06-14 | Prostaglandin e1, enthaltende emulsion und verfahren zu ihrer herstellung. |
Country Status (8)
Country | Link |
---|---|
US (1) | US4493847A (de) |
EP (1) | EP0097481B1 (de) |
JP (1) | JPS58222014A (de) |
KR (1) | KR880001756B1 (de) |
AT (1) | ATE22657T1 (de) |
CA (1) | CA1203173A (de) |
DE (1) | DE3366662D1 (de) |
ZA (1) | ZA834458B (de) |
Families Citing this family (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS59216820A (ja) * | 1983-05-20 | 1984-12-06 | Taisho Pharmaceut Co Ltd | プロスタグランジン脂肪乳剤 |
JPH0818989B2 (ja) * | 1984-01-12 | 1996-02-28 | 株式会社ミドリ十字 | 脂肪乳剤中のプロスタグランジンの安定化方法 |
JPS61289034A (ja) * | 1985-06-17 | 1986-12-19 | Teijin Ltd | イソカルバサイクリン類脂肪乳剤 |
JPS6253922A (ja) * | 1985-09-02 | 1987-03-09 | Tetsuzo Sugizaki | 腎炎予防・治療剤 |
JPS63246330A (ja) * | 1987-03-31 | 1988-10-13 | Isamu Koyama | 腎臓温阻血障害改善剤 |
US5262168A (en) * | 1987-05-22 | 1993-11-16 | The Liposome Company, Inc. | Prostaglandin-lipid formulations |
US5925375A (en) * | 1987-05-22 | 1999-07-20 | The Liposome Company, Inc. | Therapeutic use of multilamellar liposomal prostaglandin formulations |
US5811118A (en) * | 1987-05-22 | 1998-09-22 | The Liposome Company, Inc. | Methods of treatment using unilamellar liposomal arachidonic acid metabolite formulations |
US5082664A (en) * | 1987-05-22 | 1992-01-21 | The Liposome Company, Inc. | Prostaglandin-lipid formulations |
JP2600726B2 (ja) * | 1987-11-30 | 1997-04-16 | 大正製薬株式会社 | 微粒子脂肪乳剤 |
JP2926749B2 (ja) | 1989-04-25 | 1999-07-28 | 吉富製薬株式会社 | プロスタグランジン含有液状組成物 |
JPH0669966B2 (ja) * | 1989-07-05 | 1994-09-07 | 株式会社ミドリ十字 | 血管造影補助剤 |
JPH03101622A (ja) * | 1989-09-11 | 1991-04-26 | Green Cross Corp:The | 肝炎予防治療剤 |
US5194670A (en) * | 1989-10-16 | 1993-03-16 | Yutaka Mizushima, Asahi Glass Company Ltd. | Emulsion of lipid containing a prostaglandin analogue |
JP2602964B2 (ja) * | 1989-10-16 | 1997-04-23 | 裕 水島 | プロスタグランジン類縁体およびその脂肪乳剤 |
KR0151704B1 (ko) * | 1989-11-27 | 1998-10-15 | 아만 히데아키 | 지방 유제 |
US4966779A (en) * | 1989-12-21 | 1990-10-30 | Basf Corporation | Stable, water miscible emulsion comprising a fat-soluble vitamin |
US5882678A (en) * | 1990-01-12 | 1999-03-16 | The Liposome Co, Inc. | Interdigitation-fusion liposomes containing arachidonic acid metabolites |
ES2128343T3 (es) * | 1991-05-07 | 1999-05-16 | Liposome Co Inc | Formulaciones de prostaglandina liposomica. |
DK0634171T3 (da) * | 1993-02-03 | 1999-11-01 | Teijin Ltd | Farmaceutisk præparat til behandling af cerebral thrombose |
JPH0769897A (ja) * | 1993-09-01 | 1995-03-14 | Green Cross Corp:The | 血中トリグリセリド低下作用剤 |
SE9303281D0 (sv) * | 1993-10-07 | 1993-10-07 | Astra Ab | New formulation |
US5840328A (en) * | 1994-01-11 | 1998-11-24 | The Liposome Company, Inc. | Treatment using arachidonic acid metabolite and particulate formulations |
EP0857484A4 (de) * | 1995-09-13 | 2000-12-06 | Nippon Shinyaku Co Ltd | Pge1- enthaltende gefriergetrocknete zubereitung und verfahren zu deren herstellung |
US5718917A (en) * | 1995-12-15 | 1998-02-17 | Harvard Scientific Corporation | PGE-1 containing lyophilized liposomes for use in the treatment of erectile dysfunction |
DE19607296A1 (de) * | 1996-02-27 | 1997-08-28 | Kodak Ag | Heftvorrichtung zum Zusammenheften von Blättern |
DE19645657A1 (de) * | 1996-11-06 | 1998-05-28 | Rhone Poulenc Rorer Gmbh | Phospholipidische Zusammensetzung, Verfahren zur Herstellung einer derartigen Zusammensetzung und Verwendung derselben |
US6288113B1 (en) | 1997-08-27 | 2001-09-11 | Welfide Corporation | Angiogenesis promoters |
US7160660B2 (en) * | 2003-04-07 | 2007-01-09 | Canon Kabushiki Kaisha | Magnetic toner |
JP5193870B2 (ja) | 2006-09-05 | 2013-05-08 | キユーピー株式会社 | プロスタグランジン脂肪乳剤およびその製造方法、ならびにその安定化方法および乳化剤 |
WO2011144722A1 (en) | 2010-05-21 | 2011-11-24 | Nestec S.A. | Storable hot water or steam delivery device |
CN103536532A (zh) * | 2013-10-25 | 2014-01-29 | 北京蓝丹医药科技有限公司 | 一种前列地尔组合物及其制备方法 |
WO2018158179A1 (en) | 2017-02-28 | 2018-09-07 | Nestec Sa | Dispenser with parallel dispensing paths |
CN107137351B (zh) * | 2017-06-05 | 2020-08-04 | 辅必成(上海)医药科技有限公司 | 一种稳定的前列地尔乳剂注射液 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GT196914163A (es) * | 1968-08-29 | 1971-01-26 | Composicion y proceso | |
US4016290A (en) * | 1973-11-12 | 1977-04-05 | The United States Of America As Represented By The United States Energy Research And Development Administration | Method of encapsulating polyaminopolycarboxylic acid chelating agents in liposomes |
GB1575343A (en) * | 1977-05-10 | 1980-09-17 | Ici Ltd | Method for preparing liposome compositions containing biologically active compounds |
JPS6030652B2 (ja) * | 1979-05-07 | 1985-07-17 | 株式会社ミドリ十字 | 静脈注射用脂肪乳剤 |
JPS56127308A (en) * | 1980-03-11 | 1981-10-06 | Green Cross Corp:The | Blood-coagulation factor 8 pharmaceutical |
US4302459A (en) * | 1980-03-19 | 1981-11-24 | The United States Of America As Represented By The Secretary Of The Army | Liposome carriers in leishmaniasis chemotherapy with 8-aminoquinoline derivatives |
JPS609726B2 (ja) * | 1980-05-15 | 1985-03-12 | 株式会社 ミドリ十字 | ステロイド製剤 |
-
1982
- 1982-06-18 JP JP57104814A patent/JPS58222014A/ja active Granted
-
1983
- 1983-06-13 US US06/503,599 patent/US4493847A/en not_active Expired - Lifetime
- 1983-06-14 DE DE8383303427T patent/DE3366662D1/de not_active Expired
- 1983-06-14 AT AT83303427T patent/ATE22657T1/de not_active IP Right Cessation
- 1983-06-14 EP EP83303427A patent/EP0097481B1/de not_active Expired
- 1983-06-16 CA CA000430549A patent/CA1203173A/en not_active Expired
- 1983-06-17 KR KR1019830002716A patent/KR880001756B1/ko not_active IP Right Cessation
- 1983-06-17 ZA ZA834458A patent/ZA834458B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
DE3366662D1 (en) | 1986-11-13 |
JPH0157094B2 (de) | 1989-12-04 |
US4493847A (en) | 1985-01-15 |
CA1203173A (en) | 1986-04-15 |
KR840005019A (ko) | 1984-11-03 |
EP0097481A1 (de) | 1984-01-04 |
ZA834458B (en) | 1984-03-28 |
EP0097481B1 (de) | 1986-10-08 |
KR880001756B1 (ko) | 1988-09-12 |
JPS58222014A (ja) | 1983-12-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
RZN | Patent revoked |