ATE218205T1 - Vorrichtung zur simulation des einflusses des lebenden organismus auf die formveraenderung; das zufalls- und aufloeseverhalten bzw. die wirkstoffabgabe einer pharmazeutischen darreichungsform - Google Patents

Vorrichtung zur simulation des einflusses des lebenden organismus auf die formveraenderung; das zufalls- und aufloeseverhalten bzw. die wirkstoffabgabe einer pharmazeutischen darreichungsform

Info

Publication number
ATE218205T1
ATE218205T1 AT94925402T AT94925402T ATE218205T1 AT E218205 T1 ATE218205 T1 AT E218205T1 AT 94925402 T AT94925402 T AT 94925402T AT 94925402 T AT94925402 T AT 94925402T AT E218205 T1 ATE218205 T1 AT E218205T1
Authority
AT
Austria
Prior art keywords
dosage form
container
pct
head portion
piston
Prior art date
Application number
AT94925402T
Other languages
English (en)
Inventor
Joel Sinnreich
Christian Bosshard
Original Assignee
Novartis Erfind Verwalt Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Erfind Verwalt Gmbh filed Critical Novartis Erfind Verwalt Gmbh
Application granted granted Critical
Publication of ATE218205T1 publication Critical patent/ATE218205T1/de

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F21/00—Dissolving
    • B01F21/10—Dissolving using driven stirrers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N13/00—Investigating surface or boundary effects, e.g. wetting power; Investigating diffusion effects; Analysing materials by determining surface, boundary, or diffusion effects
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/44—Mixers with shaking, oscillating, or vibrating mechanisms with stirrers performing an oscillatory, vibratory or shaking movement
    • B01F31/441—Mixers with shaking, oscillating, or vibrating mechanisms with stirrers performing an oscillatory, vibratory or shaking movement performing a rectilinear reciprocating movement
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/44—Mixers with shaking, oscillating, or vibrating mechanisms with stirrers performing an oscillatory, vibratory or shaking movement
    • B01F31/445—Mixers with shaking, oscillating, or vibrating mechanisms with stirrers performing an oscillatory, vibratory or shaking movement performing an oscillatory movement about an axis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/15—Medicinal preparations ; Physical properties thereof, e.g. dissolubility
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N13/00—Investigating surface or boundary effects, e.g. wetting power; Investigating diffusion effects; Analysing materials by determining surface, boundary, or diffusion effects
    • G01N2013/006—Dissolution of tablets or the like

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Medicinal Preparation (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
AT94925402T 1993-08-06 1994-07-28 Vorrichtung zur simulation des einflusses des lebenden organismus auf die formveraenderung; das zufalls- und aufloeseverhalten bzw. die wirkstoffabgabe einer pharmazeutischen darreichungsform ATE218205T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH234993 1993-08-06
PCT/EP1994/002485 WO1995004923A1 (en) 1993-08-06 1994-07-28 Apparatus for simulating the effect of the living organism on the change in shape, the disintegration and dissolution behaviour and the active-ingredient release of a pharmaceutical dosage form

Publications (1)

Publication Number Publication Date
ATE218205T1 true ATE218205T1 (de) 2002-06-15

Family

ID=4231718

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94925402T ATE218205T1 (de) 1993-08-06 1994-07-28 Vorrichtung zur simulation des einflusses des lebenden organismus auf die formveraenderung; das zufalls- und aufloeseverhalten bzw. die wirkstoffabgabe einer pharmazeutischen darreichungsform

Country Status (8)

Country Link
US (1) US5827984A (de)
EP (1) EP0712490B1 (de)
JP (1) JP3421770B2 (de)
AT (1) ATE218205T1 (de)
AU (1) AU7533494A (de)
CA (1) CA2167196A1 (de)
DE (1) DE69430701T2 (de)
WO (1) WO1995004923A1 (de)

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US6336739B1 (en) * 2001-03-02 2002-01-08 Luke Lee Air bath dissolution tester
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US20030091630A1 (en) * 2001-10-25 2003-05-15 Jenny Louie-Helm Formulation of an erodible, gastric retentive oral dosage form using in vitro disintegration test data
DE60316344T2 (de) * 2002-12-16 2008-06-12 N.V. Organon Behälter ,vorrichtung und verfahren zur prüfung des auflösens von pharmazeutischen zusammensetzungen
US7357046B2 (en) * 2002-12-16 2008-04-15 N. V. Organon Method for dissolution testing of a pharmaceutical delivery device
US7051606B2 (en) * 2004-01-30 2006-05-30 Andrx Labs Llc Dosage form holder device and methods for immersion testing
NZ554829A (en) * 2004-11-05 2008-10-31 Smithkline Beecham Corp Dissolution device to simulate gastro-intestinal tract and analyze release rate of active agent in a pharmaceutical
FI20050385A0 (fi) * 2005-04-14 2005-04-14 Jukka Rantanen Menetelmä ja laitteisto kiinteän aineen liuottamiseksi nesteeseen
US7862552B2 (en) 2005-05-09 2011-01-04 Boston Scientific Scimed, Inc. Medical devices for treating urological and uterine conditions
JPWO2007086470A1 (ja) * 2006-01-30 2009-06-18 富山産業株式会社 口腔内崩壊錠試験器
KR20100022030A (ko) 2007-05-04 2010-02-26 스미스클라인 비참 코포레이션 약제 분석 기기 및 방법
JP5612474B2 (ja) * 2007-10-17 2014-10-22 トランスファーマ メディカル リミテッド 溶出速度の検証
DE102008024840B3 (de) * 2008-05-23 2009-11-12 Merck Patent Gmbh Vorrichtung zur Aufnahme eines Feststoffes in einer Messzelle
US7938032B2 (en) * 2008-10-30 2011-05-10 Agilent Technologies, Inc. Dissolution testing with in-situ gravimetric volume measurement
EP2284821A1 (de) * 2009-08-07 2011-02-16 Nederlandse Organisatie voor toegepast -natuurwetenschappelijk onderzoek TNO Verfahren, Vorrichtung und Computerprogrammprodukt zur Beurteilung der Desintegration einer Dosierform im Verdauungstrakt
JP5576337B2 (ja) * 2010-06-30 2014-08-20 ローム アンド ハース カンパニー 医薬剤形を溶出試験装置に分配するための送達装置
US8689439B2 (en) 2010-08-06 2014-04-08 Abbott Laboratories Method for forming a tube for use with a pump delivery system
US8377001B2 (en) 2010-10-01 2013-02-19 Abbott Laboratories Feeding set for a peristaltic pump system
US8377000B2 (en) 2010-10-01 2013-02-19 Abbott Laboratories Enteral feeding apparatus having a feeding set
KR101094962B1 (ko) * 2011-10-21 2011-12-15 한국지질자원연구원 광물 용해실험 장치
ITTO20120730A1 (it) * 2012-08-14 2014-02-15 Fond Istituto Italiano Di Tecnologia Dispositivo e metodo per determinare la cinetica di dissoluzione di nanoparticelle colloidali
ITRM20130163A1 (it) * 2013-03-18 2014-09-19 Univ Roma Dispositivi e metodo per testare film sottili e strisce
GB2515197B (en) * 2014-07-10 2015-06-24 Cambtek Ltd Improved extraction apparatus
WO2016168445A1 (en) 2015-04-17 2016-10-20 Pion Inc. Apparatus and method for the assessment of concentration profiling and permeability rates
JP6213933B2 (ja) * 2015-05-29 2017-10-18 有限会社サキダス 攪拌装置、メタン発酵装置及びバイオマス処理システム
CN105784952A (zh) * 2016-05-25 2016-07-20 延边大学 简易型流通池溶出度试验装置
ES2868885T3 (es) * 2016-08-01 2021-10-22 Hoefliger Harro Verpackung Dispositivo de calibración y procedimiento de dosificación de unidades de administración
EP3954989A4 (de) * 2019-04-08 2022-12-28 Shionogi & Co., Ltd Auflösungstestnetz
JP7261655B2 (ja) * 2019-05-15 2023-04-20 日立造船株式会社 消化器官における薬剤の溶解試験装置
US10732080B1 (en) * 2019-10-14 2020-08-04 Sotax Corporation Integrated dissolution processing and sample transfer system
CN113058448A (zh) * 2021-03-26 2021-07-02 南昌大学第二附属医院 一种体外诊断试剂的预溶解装置
CN113433277B (zh) * 2021-08-08 2022-04-01 湖南慧泽生物医药科技有限公司 药物体外溶出的循环溶出仪系统及检测药物溶出的方法

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Also Published As

Publication number Publication date
EP0712490B1 (de) 2002-05-29
WO1995004923A1 (en) 1995-02-16
JP3421770B2 (ja) 2003-06-30
DE69430701D1 (de) 2002-07-04
CA2167196A1 (en) 1995-02-16
US5827984A (en) 1998-10-27
AU7533494A (en) 1995-02-28
DE69430701T2 (de) 2002-11-07
EP0712490A1 (de) 1996-05-22
JPH09501238A (ja) 1997-02-04

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