ATE203904T1 - Immunomodulator, zelladhäsionsinhibitor und mittel zur behandlung und vorbeugung von autoimmunerkrankungen - Google Patents
Immunomodulator, zelladhäsionsinhibitor und mittel zur behandlung und vorbeugung von autoimmunerkrankungenInfo
- Publication number
- ATE203904T1 ATE203904T1 AT94912070T AT94912070T ATE203904T1 AT E203904 T1 ATE203904 T1 AT E203904T1 AT 94912070 T AT94912070 T AT 94912070T AT 94912070 T AT94912070 T AT 94912070T AT E203904 T1 ATE203904 T1 AT E203904T1
- Authority
- AT
- Austria
- Prior art keywords
- cell adhesion
- autoimmune diseases
- disease
- autoimmune
- general formula
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C07D311/24—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10746493 | 1993-04-09 | ||
PCT/JP1994/000585 WO1994023714A1 (en) | 1993-04-09 | 1994-04-07 | Immunomodulator, cell adhesion inhibitor, and agent for treating and preventing autoimmune diseases |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE203904T1 true ATE203904T1 (de) | 2001-08-15 |
Family
ID=14459856
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT94912070T ATE203904T1 (de) | 1993-04-09 | 1994-04-07 | Immunomodulator, zelladhäsionsinhibitor und mittel zur behandlung und vorbeugung von autoimmunerkrankungen |
Country Status (14)
Country | Link |
---|---|
US (2) | US5922755A (de) |
EP (1) | EP0695547B1 (de) |
JP (1) | JP3521145B2 (de) |
KR (1) | KR960701633A (de) |
AT (1) | ATE203904T1 (de) |
AU (1) | AU698990B2 (de) |
CA (1) | CA2159192C (de) |
DE (1) | DE69427907T2 (de) |
DK (1) | DK0695547T3 (de) |
ES (1) | ES2160626T3 (de) |
GR (1) | GR3036738T3 (de) |
NZ (1) | NZ263620A (de) |
PT (1) | PT695547E (de) |
WO (1) | WO1994023714A1 (de) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6306840B1 (en) | 1995-01-23 | 2001-10-23 | Biogen, Inc. | Cell adhesion inhibitors |
US7001921B1 (en) | 1995-01-23 | 2006-02-21 | Biogen Idec Ma Inc. | Cell adhesion inhibitors |
US6248713B1 (en) | 1995-07-11 | 2001-06-19 | Biogen, Inc. | Cell adhesion inhibitors |
US6239108B1 (en) | 1996-07-11 | 2001-05-29 | Biogen, Inc. | Cell adhesion inhibitors |
DK0914605T3 (da) | 1996-07-25 | 2007-09-10 | Biogen Idec Inc | Molekylemodel for VLA-4-inhibitorer |
US6686350B1 (en) | 1996-07-25 | 2004-02-03 | Biogen, Inc. | Cell adhesion inhibitors |
PL198189B1 (pl) | 1998-05-28 | 2008-06-30 | Biogen Idec Ma | (R)-N-{[4-{[(2-metylofenyloamino)-karbonylo]amino}fenylo]acetylo}-L-prolilo-3-metylo]-ß-alanina, jej zastosowanie i kompozycja farmaceutyczna ją zawierająca |
JP2001055331A (ja) * | 1999-06-11 | 2001-02-27 | Toyama Chem Co Ltd | アトピー性皮膚炎治療剤 |
JP2003506491A (ja) | 1999-08-13 | 2003-02-18 | バイオジェン インコーポレイテッド | 細胞接着インヒビター |
WO2002020509A2 (de) * | 2000-09-06 | 2002-03-14 | Bayer Aktiengesellschaft | Arzneimittel gegen virale erkrankungen |
US6875743B1 (en) | 2000-11-28 | 2005-04-05 | Biogen, Inc. | Cell adhesion inhibitors |
GB0119865D0 (en) * | 2001-08-14 | 2001-10-10 | Cancer Res Campaign Tech | DNA-PK inhibitors |
GB0119863D0 (en) * | 2001-08-14 | 2001-10-10 | Cancer Res Campaign Tech | DNA-PK inhibitors |
JP3972663B2 (ja) * | 2002-01-22 | 2007-09-05 | 松下電器産業株式会社 | 高周波信号受信装置 |
US7049313B2 (en) * | 2002-02-25 | 2006-05-23 | Kudos Pharmaceuticals Ltd. | ATM inhibitors |
CN100387231C (zh) * | 2003-03-24 | 2008-05-14 | 天津药物研究院 | 一种制备古拉替莫固体制剂的工艺及其固体制剂 |
NZ545919A (en) * | 2003-08-13 | 2009-07-31 | Kudos Pharm Ltd | Aminopyrones and their use as ATM inhibitors |
CN103356636A (zh) | 2004-05-23 | 2013-10-23 | 杰勒德·M·豪斯 | Theramutein调节剂 |
US7196112B2 (en) * | 2004-07-16 | 2007-03-27 | Biogen Idec Ma Inc. | Cell adhesion inhibitors |
AU2005286329A1 (en) * | 2004-09-20 | 2006-03-30 | Cancer Research Technology Limited | DNA-PK inhibitors |
EP1848712A1 (de) * | 2005-02-09 | 2007-10-31 | Kudos Pharmaceuticals Ltd | Atm-inhibitoren |
AR054438A1 (es) * | 2005-04-15 | 2007-06-27 | Kudos Pharm Ltd | Inhibidores de adn -pk |
US8431110B2 (en) | 2005-05-23 | 2013-04-30 | Hmi Medical Innovations, Llc. | Compounds and method of identifying, synthesizing, optimizing and profiling protein modulators |
TW200745094A (en) * | 2005-08-31 | 2007-12-16 | Kudos Pharm Ltd | ATM inhibitor |
JP4659769B2 (ja) * | 2007-01-25 | 2011-03-30 | トヨタ自動車株式会社 | 冷却装置 |
UY31232A1 (es) * | 2007-07-19 | 2009-03-02 | Compuestos derivados de dibenzotifenilamino-cromen-4-onas activas sustituidas y sus isomeros y aplicaciones | |
WO2013031831A1 (ja) | 2011-08-30 | 2013-03-07 | 富山化学工業株式会社 | 関節リウマチなどの自己免疫疾患の治療の改善方法 |
TWI583677B (zh) * | 2012-09-21 | 2017-05-21 | 日本臟器製藥股份有限公司 | 香豆素衍生物 |
RS55394B1 (sr) * | 2013-07-18 | 2017-04-28 | Toyama Chemical Co Ltd | Terapeutsko sredstvo protiv bolesti bazirano na inhibitornom efektu faktora inhibicije migracije makrofaga |
EP3106161B1 (de) | 2014-02-14 | 2019-09-25 | FUJIFILM Toyama Chemical Co., Ltd. | Präventions- oder behandlungsmittel für speicherkrankheiten von zerebraler amyloid-beta |
JP6089055B2 (ja) * | 2014-03-20 | 2017-03-01 | 日本臓器製薬株式会社 | クマリン誘導体を含有する医薬 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0753725B2 (ja) * | 1987-10-08 | 1995-06-07 | 富山化学工業株式会社 | 4h―1―ベンゾピラン―4―オン誘導体およびその塩、それらの製造法並びにそれらを含有する抗炎症剤 |
GB8907799D0 (en) * | 1989-04-06 | 1989-05-17 | Erba Carlo Spa | Heteroaryl-3-oxo-propanenitrile derivatives useful in the treatment of rheumatoid arthritis and other autoimmune diseases |
JP3086312B2 (ja) * | 1991-10-28 | 2000-09-11 | 富山化学工業株式会社 | インターロイキン6の産生抑制剤並びにその産生抑制作用が有効な疾患の治療・予防剤 |
-
1994
- 1994-04-07 DE DE69427907T patent/DE69427907T2/de not_active Expired - Lifetime
- 1994-04-07 WO PCT/JP1994/000585 patent/WO1994023714A1/ja active IP Right Grant
- 1994-04-07 ES ES94912070T patent/ES2160626T3/es not_active Expired - Lifetime
- 1994-04-07 JP JP52297194A patent/JP3521145B2/ja not_active Expired - Lifetime
- 1994-04-07 EP EP94912070A patent/EP0695547B1/de not_active Expired - Lifetime
- 1994-04-07 KR KR1019950704375A patent/KR960701633A/ko not_active Application Discontinuation
- 1994-04-07 NZ NZ263620A patent/NZ263620A/xx not_active IP Right Cessation
- 1994-04-07 US US08/530,177 patent/US5922755A/en not_active Expired - Lifetime
- 1994-04-07 CA CA002159192A patent/CA2159192C/en not_active Expired - Lifetime
- 1994-04-07 AT AT94912070T patent/ATE203904T1/de active
- 1994-04-07 AU AU64371/94A patent/AU698990B2/en not_active Expired
- 1994-04-07 PT PT94912070T patent/PT695547E/pt unknown
- 1994-04-07 DK DK94912070T patent/DK0695547T3/da active
-
1999
- 1999-07-02 US US09/346,932 patent/US6166068A/en not_active Expired - Lifetime
-
2001
- 2001-09-27 GR GR20010401595T patent/GR3036738T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
NZ263620A (en) | 1999-06-29 |
DK0695547T3 (da) | 2001-10-08 |
US6166068A (en) | 2000-12-26 |
CA2159192A1 (en) | 1994-10-27 |
ES2160626T3 (es) | 2001-11-16 |
WO1994023714A1 (en) | 1994-10-27 |
JP3521145B2 (ja) | 2004-04-19 |
EP0695547B1 (de) | 2001-08-08 |
AU698990B2 (en) | 1998-11-19 |
EP0695547A1 (de) | 1996-02-07 |
US5922755A (en) | 1999-07-13 |
EP0695547A4 (de) | 1997-05-28 |
PT695547E (pt) | 2001-12-28 |
KR960701633A (ko) | 1996-03-28 |
DE69427907T2 (de) | 2002-04-04 |
AU6437194A (en) | 1994-11-08 |
GR3036738T3 (en) | 2001-12-31 |
DE69427907D1 (de) | 2001-09-13 |
CA2159192C (en) | 2006-07-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification |