ATE200224T1 - Neue medizinische zusammensetzung - Google Patents

Neue medizinische zusammensetzung

Info

Publication number
ATE200224T1
ATE200224T1 AT93916170T AT93916170T ATE200224T1 AT E200224 T1 ATE200224 T1 AT E200224T1 AT 93916170 T AT93916170 T AT 93916170T AT 93916170 T AT93916170 T AT 93916170T AT E200224 T1 ATE200224 T1 AT E200224T1
Authority
AT
Austria
Prior art keywords
ych3
medical composition
new medical
integer
ych
Prior art date
Application number
AT93916170T
Other languages
German (de)
English (en)
Inventor
Yasuhiko Koezuka
Koji Kabaya
Kazuhiro Motoki
Original Assignee
Kirin Brewery
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kirin Brewery filed Critical Kirin Brewery
Application granted granted Critical
Publication of ATE200224T1 publication Critical patent/ATE200224T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02Acyclic radicals, not substituted by cyclic structures
    • C07H15/04Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/10Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02Acyclic radicals, not substituted by cyclic structures
    • C07H15/04Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Genetics & Genomics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT93916170T 1992-07-16 1993-07-15 Neue medizinische zusammensetzung ATE200224T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP21201592 1992-07-16
JP8521993 1993-03-19
PCT/JP1993/000984 WO1994002168A1 (fr) 1992-07-16 1993-07-15 Nouvelle composition medicamenteuse

Publications (1)

Publication Number Publication Date
ATE200224T1 true ATE200224T1 (de) 2001-04-15

Family

ID=26426239

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93916170T ATE200224T1 (de) 1992-07-16 1993-07-15 Neue medizinische zusammensetzung

Country Status (12)

Country Link
US (3) US5767092A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0650732B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JP3088461B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (1) KR100277621B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CN (1) CN1084623C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) ATE200224T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU684466B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA2140013C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE69330096T2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI950166A7 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
TW (1) TW261533B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
WO (1) WO1994002168A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5936076A (en) * 1991-08-29 1999-08-10 Kirin Beer Kabushiki Kaisha αgalactosylceramide derivatives
ATE191916T1 (de) * 1992-10-22 2000-05-15 Kirin Brewery Neues sphingolglycolipid und verwendung davon
CA2160566C (en) * 1993-04-15 2004-07-13 Tatsuo Higa Novel sphingoglycolipids and uses thereof
US6026815A (en) * 1996-10-10 2000-02-22 Gholam A. Peyman Radiopaque liquid as radiation blocking agent
JP2002226377A (ja) * 1996-10-14 2002-08-14 Kirin Brewery Co Ltd 配糖体含有末梢血幹細胞増加剤
TW555562B (en) * 1996-12-27 2003-10-01 Kirin Brewery Method for activation of human antigen-presenting cells, activated human antigen-presenting cells and use thereof
JP3382957B2 (ja) * 1997-02-05 2003-03-04 麒麟麦酒株式会社 スフィンゴ糖脂質含有凍結乾燥組成物およびその製造法
US6417167B1 (en) 1997-02-05 2002-07-09 Kirin Beer Kabushiki Kaisha Lyophilized compositions containing shingoglycolipid and process for preparing them
CN1222293C (zh) 1997-04-10 2005-10-12 麒麟麦酒株式会社 含有α-糖基神经酰胺的NKT细胞活化剂
TW575420B (en) * 1997-09-22 2004-02-11 Kirin Brewery Composition for enhancing cellular immunogenicity comprising alpha-glycosylceramides
AU2001268564A1 (en) * 2000-06-22 2002-01-02 The Brigham And Women's Hospital, Inc. Alpha-glycosylceramides for treating bacterial and fungal infections
CA2453880A1 (en) * 2001-07-25 2003-02-06 New York University Use of glycosylceramides as adjuvants for vaccines against infections and cancer
JP4064346B2 (ja) * 2001-08-16 2008-03-19 アスビオファーマ株式会社 新規な糖脂質及びこれを有効成分とする自己免疫疾患治療薬
US8443383B2 (en) * 2002-05-03 2013-05-14 Time Warner Cable Enterprises Llc Use of messages in program signal streams by set-top terminals
WO2004026318A1 (ja) * 2002-09-20 2004-04-01 Kirin Beer Kabushiki Kaisha α-グリコシルセラミドを有効成分とするC型肝炎ウイルス抑制剤
US7645873B2 (en) * 2003-03-20 2010-01-12 The Scripps Research Institute 6″-amino-6″-deoxygalactosylceramides
EP1611147A4 (en) * 2003-03-20 2007-10-17 Univ Brigham Young 6 "amino-6" -DEOXYGALACTOSYLCERAMIDE
US7309015B2 (en) * 2004-07-14 2007-12-18 Scanbuy, Inc. Mobile device gateway providing access to instant information
US8513008B2 (en) 2004-10-07 2013-08-20 Argos Therapeutics, Inc. Mature dendritic cell compositions and methods for culturing same
CN101080487B (zh) 2004-10-07 2012-11-14 阿戈斯治疗公司 成熟树突细胞组合物及其培养方法
US7923013B2 (en) * 2004-12-28 2011-04-12 The Rockefeller University Glycolipids and analogues thereof as antigens for NKT cells
US7534434B2 (en) * 2004-12-28 2009-05-19 The Rockefeller University Glycolipids and analogues thereof as antigens for NK T cells
BRPI0607299A2 (pt) 2005-01-28 2009-08-25 Univ Brigham Young ativação de glicolipìdio bacteriano de células nkt restritas a cd1d
US20090036658A1 (en) * 2005-03-04 2009-02-05 The Regents Of The University Of California Highly efficient synthesis of alpha-O-galactosyl ceramides
EP1905766A1 (en) * 2005-07-01 2008-04-02 Japan as represented by President of National Center of Neurology and Psychiatry Glycolipid derivative and therapeutic agent comprising the same as active ingredient
EP1776963A1 (en) 2005-10-19 2007-04-25 Gbf-Gesellschaft Für Biotechnologische Forschung Mbh Hexosylceramides as adjuvants and their uses in pharmaceutical compositions
US20070231344A1 (en) * 2005-10-28 2007-10-04 The Brigham And Women's Hospital, Inc. Conjugate vaccines for non-proteinaceous antigens
AU2007234753B2 (en) 2006-04-07 2013-02-21 Brigham Young University Modified -galactosyl ceramides for staining and stimulating Natural Killer T cells
BRPI0713330A2 (pt) * 2006-06-30 2012-04-17 The Scripps Research Institute adjuvantes e métodos de uso
US8263576B2 (en) * 2006-08-15 2012-09-11 Mayo Foundation For Medical Education And Research Non-natural sphingolipid analogs and uses thereof
US8916164B2 (en) * 2007-08-29 2014-12-23 Abivax Methods of enhancing adjuvaticity of vaccine compositions
EP2483287B1 (en) * 2007-10-12 2016-03-16 Luigi Panza Analogues of glycolipids useful as immunoadjuvants
EP2058011A1 (en) * 2007-11-07 2009-05-13 Wittycell Nkt cell activating gycolipids covalently bound antigens and/or drug
WO2009101475A2 (en) * 2007-12-05 2009-08-20 Wittycell S.A.S. Compositions for and methods of enhancing the immune response to antigens
JP5809560B2 (ja) * 2008-10-08 2015-11-11 アビヴァックス インフルエンザに対して使用するためのワクチン組成物
KR101688547B1 (ko) 2009-02-16 2016-12-21 세레니스 쎄라퓨틱스 홀딩 에스에이 아포리포단백질 a-i 모방체
NZ621551A (en) 2010-10-18 2015-09-25 Cerenis Therapeutics Holding Sa Compounds, compositions and methods useful for cholesterol mobilisation
ES2675582T3 (es) 2010-12-02 2018-07-11 Riken Inmunoterapia utilizando células alo-NKT, células para inmunoterapia en las que la cadena alfa del gen del receptor de las células T (TCR) ha sido redistribuida a V alfa-J alfa uniforme, y banco de células NKT derivadas de dichas células
WO2013119857A1 (en) 2012-02-07 2013-08-15 The Regents Of The University Of California Glycosphingolipids for use in modulating immune responses
CA2882553A1 (en) 2012-08-22 2013-08-22 Regimmune Corporation Preparation for preventing or treating type i diabetes
WO2014059220A1 (en) 2012-10-12 2014-04-17 The Brigham And Women's Hospital, Inc. Glycosphingolipids and methods of use thereof
AU2013339046A1 (en) 2012-11-05 2015-05-21 Regimmune Corporation Immune-tolerance inducer
JP6599233B2 (ja) 2012-11-21 2019-10-30 アンセルム(アンスティチュート・ナシオナル・ドゥ・ラ・サンテ・エ・ドゥ・ラ・ルシェルシュ・メディカル) 急性移植片対宿主病のリスクを決定する方法
JP2015205835A (ja) * 2014-04-21 2015-11-19 国立大学法人福井大学 中性子線障害防護剤
AU2021392472A1 (en) 2020-12-04 2023-07-06 Osaka University Cd1d-ligand-compound-containing liposome preparation having improved pharmacokinetics

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3622666A (en) * 1968-03-04 1971-11-23 Stanley Drug Products Inc Methods for treating bacterial infections with phrenosin
US4598051A (en) * 1980-03-12 1986-07-01 The Regents Of The University Of California Liposome conjugates and diagnostic methods therewith
US4806466A (en) * 1981-10-29 1989-02-21 The Regents Of The University Of California Cell agglutination reagent comprising conjugates of antibody covalently bound to liposomes
IT1168205B (it) * 1983-07-21 1987-05-20 Wellcome Italia Derivato di monsialo ganglioside dotato di attivita' antibatterica, antifungina ed antitumorale, composizioni che lo contengono e procedimento per la loro preparazione
EP0146810A3 (de) * 1983-12-05 1987-05-13 Solco Basel AG Verfahren zur Herstellung von Sphingosinderivaten
JPS6157594A (ja) * 1984-08-30 1986-03-24 Suntory Ltd ガラクトスフインゴ脂質及びその製造法
DK17885D0 (da) * 1985-01-14 1985-01-14 Karlsson Karl Anders Antiviralt middel
ZA866023B (en) * 1985-08-13 1987-03-25 Solco Basel Ag New process for the preparation of sphingosine derivatives
JPH07116209B2 (ja) * 1986-04-11 1995-12-13 メクト株式会社 シアロシルセラミド類及びその製造方法
US4990603A (en) * 1986-07-04 1991-02-05 Mect Corporation Sialic acid derivatives and process therefor
US4937232A (en) * 1986-09-15 1990-06-26 Duke University Inhibition of protein kinase C by long-chain bases
US4816450A (en) * 1986-09-15 1989-03-28 Duke University Inhibition of protein kinase C by long-chain bases
JPS6495A (en) * 1986-12-19 1989-01-05 Tosoh Corp Alpha-glycosyl ceramide derivative
US5026557A (en) * 1987-09-09 1991-06-25 The Liposome Company, Inc. Adjuvant composition
JP2588729B2 (ja) * 1987-10-05 1997-03-12 塩野義製薬株式会社 スフィンゴシン誘導体
US5041441A (en) * 1988-04-04 1991-08-20 The Regents Of The University Of Michigan Method of chemotherapy using 1-phenyl-2-decanoylamino-3-morpholino-1-propanol
US5073543A (en) * 1988-07-21 1991-12-17 G. D. Searle & Co. Controlled release formulations of trophic factors in ganglioside-lipsome vehicle
JP2631532B2 (ja) * 1988-10-14 1997-07-16 富士写真フイルム株式会社 熱転写受像材料
DE3840044A1 (de) * 1988-11-27 1990-06-07 Behringwerke Ag Glykosphingolipide mit kopplungsfaehiger gruppe im sphingoidanteil, ihre herstellung und verwendung
IT1235162B (it) * 1988-12-02 1992-06-22 Fidia Farmaceutici Derivati di lisosfingolipidi
US5028715A (en) * 1989-02-06 1991-07-02 Southwest Research Institute Radioprotective agents and their method of manufacture
US5210073A (en) * 1989-09-29 1993-05-11 Ajinomoto Co., Inc. Method for treating cancer therapy radiation damage or arteriosclerosis using human adf
JP3068910B2 (ja) * 1990-11-08 2000-07-24 麒麟麦酒株式会社 新規スフィンゴ糖脂質、その製造法および使用
JPH06145189A (ja) * 1991-01-23 1994-05-24 Kitasato Inst:The スフィンゴ糖脂質
JP3034650B2 (ja) * 1991-06-19 2000-04-17 株式会社ジーシー 歯質用接着剤
JPH0559081A (ja) * 1991-08-29 1993-03-09 Kirin Brewery Co Ltd 新規スフインゴ糖脂質、その製造法および使用
CA2160566C (en) * 1993-04-15 2004-07-13 Tatsuo Higa Novel sphingoglycolipids and uses thereof

Also Published As

Publication number Publication date
EP0650732A1 (en) 1995-05-03
US6017892A (en) 2000-01-25
DE69330096D1 (de) 2001-05-10
US5767092A (en) 1998-06-16
FI950166A0 (fi) 1995-01-13
CN1088093A (zh) 1994-06-22
US6071884A (en) 2000-06-06
TW261533B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1995-11-01
KR950702431A (ko) 1995-07-29
KR100277621B1 (ko) 2001-02-01
AU684466B2 (en) 1997-12-18
AU4583593A (en) 1994-02-14
JP3088461B2 (ja) 2000-09-18
CA2140013C (en) 2002-08-27
HK1009937A1 (en) 1999-09-17
EP0650732A4 (en) 1998-04-01
CA2140013A1 (en) 1994-02-03
CN1084623C (zh) 2002-05-15
FI950166A7 (fi) 1995-01-31
DE69330096T2 (de) 2001-10-18
EP0650732B1 (en) 2001-04-04
WO1994002168A1 (fr) 1994-02-03

Similar Documents

Publication Publication Date Title
ATE200224T1 (de) Neue medizinische zusammensetzung
FI941986A0 (fi) Antifungaaliset tri-substituoidut tetrahydrofuraanit
ATE167857T1 (de) Azolverbindungen, deren herstellung und verwendung
DE69111619D1 (de) 1,4-benzothiazedinderivat.
ATE161873T1 (de) Strahlungshärtbare zusammensetzungen
EP0632031A4 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES2072223B1 (es) Liposomas encapsulando doxorubicina.
NO922674L (no) Spikamycinderivater og anvendelse derav
ATE153666T1 (de) Phosphono-arylethanolamin-verbindungen mit antihyperglykämischer und/oder antiobeser wirkung
ATE109770T1 (de) Derivate der coffeinsäure und pharmazeutische zusammensetzungen, die sie enthalten.
EP0712398A1 (en) BENZOPYRANS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
HUT49887A (en) Process for producing new cefem compounds
TW198031B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA2052020A1 (en) Pradimicin derivatives
NO933691L (no) Tiokarbamatsulfoksydsammensetning for avholdenhet fra inntakelse av etanol
TW218020B (en) A protective agent against irradiation damage
MY115174A (en) N-hydroxyureas as antiinflammatory agents

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties