ATE157666T1 - Verfahren zur selektiven herstellung von hydratkristallen - Google Patents
Verfahren zur selektiven herstellung von hydratkristallenInfo
- Publication number
- ATE157666T1 ATE157666T1 AT91103032T AT91103032T ATE157666T1 AT E157666 T1 ATE157666 T1 AT E157666T1 AT 91103032 T AT91103032 T AT 91103032T AT 91103032 T AT91103032 T AT 91103032T AT E157666 T1 ATE157666 T1 AT E157666T1
- Authority
- AT
- Austria
- Prior art keywords
- methyl
- selective production
- hydrate crystals
- benzoxazine
- pyrido
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/06—Peri-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP5045490 | 1990-03-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE157666T1 true ATE157666T1 (de) | 1997-09-15 |
Family
ID=12859314
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT91103032T ATE157666T1 (de) | 1990-03-01 | 1991-02-28 | Verfahren zur selektiven herstellung von hydratkristallen |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US5545737A (de) |
| EP (1) | EP0444678B1 (de) |
| KR (1) | KR970000045B1 (de) |
| AT (1) | ATE157666T1 (de) |
| DE (1) | DE69127485T2 (de) |
| ES (1) | ES2106739T3 (de) |
| GR (1) | GR3025276T3 (de) |
| HK (1) | HK1002730A1 (de) |
| IE (1) | IE910692A1 (de) |
| IN (1) | IN172207B (de) |
| PT (1) | PT96917B (de) |
| TW (1) | TW208013B (de) |
| YU (1) | YU48328B (de) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA946853B (en) * | 1993-09-10 | 1995-04-24 | Daiichi Seiyaku Co | Crystals of antimicrobial compound. |
| US6562974B2 (en) | 2000-02-01 | 2003-05-13 | The Procter & Gamble Company | Process for making geminal bisphosphonates |
| PE20011061A1 (es) | 2000-02-01 | 2001-11-20 | Procter & Gamble | Cristalizacion selectiva del acido 3-piridil-1-hidroxi-etiliden-1,1-bisfosfonico sodio como el hemipentahidrato o el monohidrato |
| US7425628B2 (en) * | 2001-10-03 | 2008-09-16 | Teva Pharmaceutical Industries Ltd. | Methods for the purification of levofloxacin |
| IL161164A0 (en) † | 2001-10-03 | 2004-08-31 | Teva Pharma | Preparation of levofloxacin and forms thereof |
| IL162172A0 (en) * | 2001-11-29 | 2005-11-20 | Teva Pharma | Methods for the purification of levofloxacin |
| WO2004055025A1 (en) * | 2002-12-16 | 2004-07-01 | Ranbaxy Laboratories Limited | Pure levofloxacin hemihydrate and processes for preparation thereof |
| KR100704641B1 (ko) * | 2004-07-21 | 2007-04-06 | 주식회사유한양행 | 고순도의 레보플록사신 제조방법 |
| WO2006030452A1 (en) * | 2004-09-17 | 2006-03-23 | Matrix Laboratories Ltd | An improved process for the preparation of levofloxacin hemihydrate |
| US20070244318A1 (en) * | 2004-11-08 | 2007-10-18 | Rao Davuluri R | Process for the Preparation of Levofloxacin Hemihydrate |
| ES2255871B1 (es) * | 2004-12-31 | 2007-08-16 | Quimica Sintetica, S.A. | Procedimiento para la obtencion de levofloxacino exento de sales. |
| CN1321121C (zh) * | 2005-04-21 | 2007-06-13 | 浙江医药股份有限公司新昌制药厂 | 左氧氟沙星制备及后处理方法 |
| US7964723B2 (en) * | 2008-08-02 | 2011-06-21 | Apeloa-Kangyu | And practical process for exclusively producing (S)-9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido-[1,2,3,de][1,4]benzoxazine-6-carboxylic acid hemihydrate |
| CN101863904A (zh) * | 2010-07-08 | 2010-10-20 | 浙江东亚药业有限公司 | 一种高纯度左氧氟沙星半水合物的制备方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE203719C (de) * | 1907-11-02 | 1908-10-20 | ||
| JPS5746986A (en) * | 1980-09-02 | 1982-03-17 | Dai Ichi Seiyaku Co Ltd | Pyrido(1,2,3-de)(1,4)benzoxazine derivative |
| JPS57131769A (en) * | 1981-02-10 | 1982-08-14 | Kissei Pharmaceut Co Ltd | 4-(1-imidazolylmethyl)cinnamic acid hydrochloride monohydrate, its preparation and drug containing the same |
| JPS5843977A (ja) * | 1981-09-09 | 1983-03-14 | Dai Ichi Seiyaku Co Ltd | ピリドベンズオキサジン誘導体の製法 |
| JPS60226855A (ja) * | 1984-04-26 | 1985-11-12 | Nippon Kayaku Co Ltd | Ｎ−ベンジルオキシカルボニル−ｌ−スレオニンアミド・１／２水和物およびその製造法 |
| ZA864518B (en) * | 1985-06-20 | 1987-03-25 | Daiichi Seiyaku Co | Optically active pyridobenzoxazine derivatives and intermediates thereof |
| DK170473B1 (da) * | 1985-06-20 | 1995-09-11 | Daiichi Seiyaku Co | S(-)-pyridobenzoxazinforbindelser |
| MY104139A (en) * | 1988-08-09 | 1994-02-28 | Daiichi Seiyaku Co | Antimicrobial agent for animals |
| FI82240C (fi) * | 1988-10-20 | 1991-02-11 | Huhtamaeki Oy | Foerfarande foer framstaellning av farmakologiskt vaerdefullt s-timolol-hemihydrat. |
| MTP1076B (en) * | 1990-01-12 | 1991-09-30 | Ciba Geigy Ag | Hemihydrate |
-
1990
- 1990-03-13 TW TW080108336A patent/TW208013B/zh active
-
1991
- 1991-02-28 DE DE69127485T patent/DE69127485T2/de not_active Expired - Lifetime
- 1991-02-28 AT AT91103032T patent/ATE157666T1/de not_active IP Right Cessation
- 1991-02-28 IN IN175/MAS/91A patent/IN172207B/en unknown
- 1991-02-28 PT PT96917A patent/PT96917B/pt not_active IP Right Cessation
- 1991-02-28 KR KR1019910003413A patent/KR970000045B1/ko not_active IP Right Cessation
- 1991-02-28 YU YU35491A patent/YU48328B/sh unknown
- 1991-02-28 EP EP91103032A patent/EP0444678B1/de not_active Expired - Lifetime
- 1991-02-28 ES ES91103032T patent/ES2106739T3/es not_active Expired - Lifetime
- 1991-03-01 IE IE069291A patent/IE910692A1/en not_active IP Right Cessation
-
1994
- 1994-01-18 US US08/182,364 patent/US5545737A/en not_active Expired - Lifetime
-
1997
- 1997-11-05 GR GR970402914T patent/GR3025276T3/el unknown
-
1998
- 1998-02-27 HK HK98101536A patent/HK1002730A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| GR3025276T3 (en) | 1998-02-27 |
| ES2106739T3 (es) | 1997-11-16 |
| KR970000045B1 (ko) | 1997-01-04 |
| DE69127485T2 (de) | 1998-04-02 |
| KR910016748A (ko) | 1991-11-05 |
| IE910692A1 (en) | 1991-09-11 |
| PT96917B (pt) | 1998-07-31 |
| PT96917A (pt) | 1991-10-31 |
| TW208013B (de) | 1993-06-21 |
| HK1002730A1 (en) | 1998-09-11 |
| EP0444678B1 (de) | 1997-09-03 |
| IN172207B (de) | 1993-05-01 |
| EP0444678A1 (de) | 1991-09-04 |
| YU48328B (sh) | 1998-05-15 |
| DE69127485D1 (de) | 1997-10-09 |
| YU35491A (sh) | 1994-04-05 |
| US5545737A (en) | 1996-08-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| EEIH | Change in the person of patent owner | ||
| EELA | Cancelled due to lapse of time |