ATE147776T1 - Verfahren zur chromatografischer fraktionierung von fettsäuren und ihre derivaten - Google Patents

Verfahren zur chromatografischer fraktionierung von fettsäuren und ihre derivaten

Info

Publication number
ATE147776T1
ATE147776T1 AT94914635T AT94914635T ATE147776T1 AT E147776 T1 ATE147776 T1 AT E147776T1 AT 94914635 T AT94914635 T AT 94914635T AT 94914635 T AT94914635 T AT 94914635T AT E147776 T1 ATE147776 T1 AT E147776T1
Authority
AT
Austria
Prior art keywords
pct
pufa
recovering
fatty acids
sec
Prior art date
Application number
AT94914635T
Other languages
English (en)
Inventor
Michel Perrut
Roger-Marc Nicoud
Harald Breivik
Original Assignee
Norsk Hydro As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB939308912A external-priority patent/GB9308912D0/en
Priority claimed from GB939322310A external-priority patent/GB9322310D0/en
Application filed by Norsk Hydro As filed Critical Norsk Hydro As
Application granted granted Critical
Publication of ATE147776T1 publication Critical patent/ATE147776T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B7/00—Separation of mixtures of fats or fatty oils into their constituents, e.g. saturated oils from unsaturated oils
    • C11B7/0008—Separation of mixtures of fats or fatty oils into their constituents, e.g. saturated oils from unsaturated oils by differences of solubilities, e.g. by extraction, by separation from a solution by means of anti-solvents
    • C11B7/005—Separation of mixtures of fats or fatty oils into their constituents, e.g. saturated oils from unsaturated oils by differences of solubilities, e.g. by extraction, by separation from a solution by means of anti-solvents in solvents used at superatmospheric pressures
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B3/00—Refining fats or fatty oils
    • C11B3/16—Refining fats or fatty oils by mechanical means
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11C—FATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
    • C11C1/00—Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids
    • C11C1/08—Refining

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Mechanical Engineering (AREA)
  • Analytical Chemistry (AREA)
  • Fats And Perfumes (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT94914635T 1993-04-29 1994-04-29 Verfahren zur chromatografischer fraktionierung von fettsäuren und ihre derivaten ATE147776T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB939308912A GB9308912D0 (en) 1993-04-29 1993-04-29 Process for chromatographic fractionation of fatty acids and their derivatives
GB939322310A GB9322310D0 (en) 1993-10-29 1993-10-29 Process for chromatographic fractionation of fatty acids and their derivatives

Publications (1)

Publication Number Publication Date
ATE147776T1 true ATE147776T1 (de) 1997-02-15

Family

ID=26302830

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94914635T ATE147776T1 (de) 1993-04-29 1994-04-29 Verfahren zur chromatografischer fraktionierung von fettsäuren und ihre derivaten

Country Status (10)

Country Link
US (1) US5719302A (de)
EP (1) EP0697034B1 (de)
JP (1) JPH08512336A (de)
AT (1) ATE147776T1 (de)
AU (1) AU676910B2 (de)
CA (1) CA2159823C (de)
DE (1) DE69401506T2 (de)
DK (1) DK0697034T3 (de)
ES (1) ES2097047T3 (de)
WO (1) WO1994025552A1 (de)

Families Citing this family (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08218091A (ja) * 1995-02-17 1996-08-27 Maruha Corp 高純度の高度不飽和脂肪酸およびその誘導体の製造方法
DK0760393T3 (da) * 1995-08-17 2003-09-29 Hoffmann La Roche Kromatografifremgangsmåde
FR2783021B1 (fr) * 1998-09-09 2000-10-13 Inst Francais Du Petrole Procede et systeme de pompage de fluide utilisant une pompe avec un debit constant a l'aspiration ou au refoulement
US6399803B1 (en) 1999-02-26 2002-06-04 Omegatech, Inc. Process for separating a triglyceride comprising a docosahexaenoic acid residue from a mixture of triglycerides
DE19923558A1 (de) * 1999-05-21 2000-11-23 K D Pharma Bexbach Gmbh Verfahren zur Herstellung von geruchs- und geschmacksfreien ungesättigten Fettsäuren aus Naturölen und deren Verwendung
US6740243B2 (en) 2000-11-15 2004-05-25 Purdue Research Foundation Systems and processes for performing separations using a simulated moving bed apparatus
RU2003133734A (ru) * 2001-04-20 2005-02-27 Дау Глобал Текнолоджиз Инк. (Us) Разделение смесей триглицеридов растительных масел адсорбцией на твердом слое
DE10159987A1 (de) * 2001-12-06 2003-06-26 Nutrinova Gmbh Verfahren zur Aufreinigung von Glycerolether enthaltenden Mischungen
EP2295529B2 (de) 2002-07-11 2022-05-18 Basf As Verfahren zur Verminderung von Umweltschadstoffen in einem Öl oder einem Fett und Fischfutterprodukt
SE0202188D0 (sv) * 2002-07-11 2002-07-11 Pronova Biocare As A process for decreasing environmental pollutants in an oil or a fat, a volatile fat or oil environmental pollutants decreasing working fluid, a health supplement, and an animal feed product
DE10235385B4 (de) * 2002-08-02 2006-10-05 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Verfahren zur chromatographischen Trennung von Komponenten
NZ523920A (en) 2003-01-31 2005-11-25 Fonterra Co Operative Group Methods for extracting lipids from diary products using a near critical phase fluid
FR2894772B1 (fr) * 2005-12-20 2008-03-14 Pierre Fabre Medicament Sa Procede d'enrichissement en dha
EP1982752B1 (de) * 2007-04-17 2010-08-25 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Verfahren und Vorrichtung zur chromatographischen Trennung von Komponenten mit teilweiser Rückführung von Gemischfraktionen
DE102007049718A1 (de) 2007-10-16 2009-04-23 Sepura Gmbh Verarbeitung von Harnstoffkristallisaten aus der Fischölverarbeitung
EP2247356A1 (de) 2008-02-21 2010-11-10 Dow Global Technologies Inc. Trennung natürlicher, aus öl abgeleiteter aldehyde oder hydroxymethylester mithilfe einer prozesschromatographie
KR101357298B1 (ko) * 2008-06-20 2014-01-28 에이케이 앤 엠엔 바이오팜 주식회사 오메가-3계 고도불포화 지방산의 고순도 정제방법
US8362080B2 (en) 2008-12-18 2013-01-29 Baylor College Of Medicine Increasing glutathione levels for therapy
ES2459951T3 (es) * 2009-12-30 2014-05-13 Basf Pharma (Callanish) Limited Proceso de separación cromatográfico de lecho móvil simulado para la purificación de ácidos grasos poliinsaturados
JP5416861B2 (ja) † 2011-03-03 2014-02-12 日本水産株式会社 リパーゼによる高度不飽和脂肪酸含有油脂の製造方法
GB201111595D0 (en) 2011-07-06 2011-08-24 Equateq Ltd Improved process
GB201111594D0 (en) * 2011-07-06 2011-08-24 Equateq Ltd New improved process
GB201111601D0 (en) * 2011-07-06 2011-08-24 Equateq Ltd New process
GB201111589D0 (en) * 2011-07-06 2011-08-24 Equateq Ltd New modified process
GB201111591D0 (en) * 2011-07-06 2011-08-24 Equateq Ltd Further new process
ES2395320B1 (es) 2011-07-14 2013-12-18 Soluciones Extractivas Alimentarias, S.L. Nuevo método para la reducción de contaminantes en grasas y aceites a partir de aceites y sus derivados.
WO2013083482A1 (en) * 2011-12-05 2013-06-13 Chromacon Ag Chromatographic method for the separation of fatty acid mixtures
US20150004224A1 (en) 2012-01-06 2015-01-01 Omthera Phrmaceuticals, Inc. Dpa-enriched compositions of omega-3 polyunsaturated fatty acids in free acid form
CN103508876A (zh) * 2012-06-27 2014-01-15 江苏汉邦科技有限公司 模拟移动床分离提纯epa的方法
EP2682168A1 (de) 2012-07-02 2014-01-08 Millipore Corporation Reinigung biologischer Moleküle
US9629820B2 (en) 2012-12-24 2017-04-25 Qualitas Health, Ltd. Eicosapentaenoic acid (EPA) formulations
US10123986B2 (en) 2012-12-24 2018-11-13 Qualitas Health, Ltd. Eicosapentaenoic acid (EPA) formulations
GB201300354D0 (en) * 2013-01-09 2013-02-20 Basf Pharma Callanish Ltd Multi-step separation process
EP2948751A4 (de) * 2013-01-25 2016-08-31 Waters Technologies Corp Verfahren und vorrichtung zur analyse von fettsäuren
CA2911273C (en) * 2013-05-07 2021-04-27 Groupe Novasep Chromatographic process for the production of highly purified polyunsaturated fatty acids
US9428711B2 (en) 2013-05-07 2016-08-30 Groupe Novasep Chromatographic process for the production of highly purified polyunsaturated fatty acids
US8802880B1 (en) 2013-05-07 2014-08-12 Group Novasep Chromatographic process for the production of highly purified polyunsaturated fatty acids
EP2801604B1 (de) 2013-05-07 2017-04-12 Groupe Novasep Chromatographisches Verfahren zur Herstellung von hochreinen, mehrfach ungesättigten Fettsäuren
JP6302310B2 (ja) * 2013-08-30 2018-03-28 備前化成株式会社 高純度オメガ３系脂肪酸エチルエステルの生産方法
EP3063260B1 (de) * 2013-10-28 2019-01-09 Totally Natural Solutions Ltd Fraktionierung von hopfenölen mit flüssigem und überkritischem kohlendioxid
KR101533508B1 (ko) * 2013-11-25 2015-07-22 연세대학교 산학협력단 혼합물 분리향상을 위한 세 구역 세 포트 유사 이동층 흡착 분리 공정의 운전 방법
FR3014435B1 (fr) * 2013-12-11 2016-10-21 Novasep Process Purification d'acides gras par un procede chromatographique
FR3014436B1 (fr) * 2013-12-11 2016-10-21 Novasep Process Procede de purification chromatographique d'un acide gras
EP3118186B1 (de) 2013-12-11 2022-02-09 Novasep Process Chromatografische anlage zur herstellung von mehrfach ungesättigten fettsäuren
US10975031B2 (en) 2014-01-07 2021-04-13 Novasep Process Method for purifying aromatic amino acids
US9163198B2 (en) * 2014-01-17 2015-10-20 Orochem Technologies, Inc. Process for purification of EPA (eicosapentanoic acid) ethyl ester from fish oil
US9546125B2 (en) 2015-02-11 2017-01-17 Orochem Technologies, Inc. Continuous process for extraction of unsaturated triglycerides from fish oil
SG10201912645TA (en) 2015-08-31 2020-02-27 Nippon Suisan Kaisha Ltd Free-polyunsaturated-fatty-acid-containing composition and method for manufacturing same
CN107543870A (zh) * 2016-06-29 2018-01-05 江苏汉邦科技有限公司 半制备型超临界流体色谱仪
TWI648258B (zh) * 2017-07-10 2019-01-21 喬璞科技有限公司 純化不飽和脂肪酸以及二十碳五烯酸的方法
TWI648393B (zh) * 2017-08-15 2019-01-21 喬璞科技有限公司 純化不飽和脂肪酸以及純化亞麻酸的方法
EP3586640A1 (de) 2018-06-21 2020-01-01 Nuseed Pty Ltd Dha-angereicherte mehrfach ungesättigte fettsäurezusammensetzungen
LU500141B1 (de) * 2021-05-10 2022-11-10 K D Pharma Bexbach Gmbh Chromatographieverfahren und -vorrichtung, insbesondere Verfahren und Vorrichtung zur superkritischen Flüssigkeitschromatographie
WO2022238046A1 (de) * 2021-05-10 2022-11-17 K.D. Pharma Bexbach Gmbh Chromatographieverfahren und -vorrichtung, insbesondere verfahren und vorrichtung zur superkritischen flüssigkeitschromatographie
CN114349638A (zh) * 2021-12-21 2022-04-15 江苏汉邦科技有限公司 一种乙酯型鱼油中欧米伽-3-酸乙酯的纯化方法
CN115010596B (zh) * 2022-07-01 2024-01-30 江苏汉邦科技股份有限公司 一种鱼油原料中二十碳五烯酸的富集方法

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2985589A (en) * 1957-05-22 1961-05-23 Universal Oil Prod Co Continuous sorption process employing fixed bed of sorbent and moving inlets and outlets
US3761533A (en) * 1970-07-23 1973-09-25 Toray Industries Separation process of components of feed mixture utilizing solid sorbent
US3706812A (en) * 1970-12-07 1972-12-19 Universal Oil Prod Co Fluid-solid contacting apparatus
US3696107A (en) * 1971-05-27 1972-10-03 Richard W Neuzil Improved hydrocarbon separation process
AT347551B (de) * 1972-06-26 1979-01-10 Studiengesellschaft Kohle Mbh Verfahren zur desodorisierung von fetten und oelen
AT328597B (de) * 1973-08-30 1976-03-25 Studiengesellschaft Kohle Mbh Verfahren zur gleichzeitigen hydrierung und desodorisierung von fetten und/oder olen
US4124528A (en) * 1974-10-04 1978-11-07 Arthur D. Little, Inc. Process for regenerating adsorbents with supercritical fluids
DE2609846C2 (de) * 1976-03-10 1982-05-19 Sachs Systemtechnik Gmbh, 8720 Schweinfurt Trinkwasser-Reinigungsgerät
US4147624A (en) * 1976-04-15 1979-04-03 Arthur D. Little, Inc. Wastewater treatment with desorbing of an adsorbate from an adsorbent with a solvent in the near critical state
FR2527934A1 (fr) * 1982-06-03 1983-12-09 Elf Aquitaine Procede de fractionnement de melanges par chromatographie d'elution avec fluide en etat supercritique et installation pour sa mise en oeuvre
JPH0664032B2 (ja) * 1985-10-12 1994-08-22 出光石油化学株式会社 超臨界流体による混合物からの特定成分の分離方法
JPS63112536A (ja) * 1986-10-30 1988-05-17 Agency Of Ind Science & Technol γ−リノレン酸の濃縮精製方法
JPS63216845A (ja) * 1987-03-05 1988-09-09 Agency Of Ind Science & Technol γ−リノレン酸の濃縮方法
JPH01169354A (ja) * 1987-12-25 1989-07-04 Hitachi Ltd 超臨界炭酸ガス抽出物の分取方法
NO163139C (no) * 1988-01-22 1990-04-11 Norsk Hydro As Fremgangsmaate for fremstilling av n-3 flerumettede fettsyrer og deres derivater, spesielt lavere alkylestere fra tidligere oppkonsentrert foede.
GB8819110D0 (en) * 1988-08-11 1988-09-14 Norsk Hydro As Antihypertensive drug & method for production
JPH0796508B2 (ja) * 1988-12-13 1995-10-18 三菱重工業株式会社 脂肪族アルコールエトキシレートの分画方法
JPH02289692A (ja) * 1989-02-16 1990-11-29 Shokuhin Sangyo Hai Separeeshiyon Syst Gijutsu Kenkyu Kumiai α―リノレン酸高含有トリグリセライドの濃縮方法
JPH0768169B2 (ja) * 1989-03-30 1995-07-26 千代田化工建設株式会社 エイコサペンタエン酸エステル及び／又はドコサヘキサエン酸エステルの分離方法
CH678181A5 (de) * 1989-05-22 1991-08-15 Nestle Sa
JP2742569B2 (ja) * 1989-08-08 1998-04-22 千代田化工建設株式会社 ω３位及びω６位に２重結合を有する高度不飽和脂肪酸エステルの分離方法
FR2651149B1 (fr) * 1989-08-28 1992-06-05 Inst Francais Du Petrole Procede continu et dispositif de separation chromatographique d'un melange d'au moins trois constituants en trois effluents purifies au moyen d'un seul solvant a deux temperatures et/ou a deux pressions differentes.
FR2651148B1 (fr) * 1989-08-28 1992-05-07 Inst Francais Du Petrole Procede continu et dispositif de separation chromatographique d'un melange d'au moins trois constituants en trois effluents purifies au moyen de deux solvants.
JP3400466B2 (ja) * 1991-10-28 2003-04-28 日本水産株式会社 高純度エイコサペンタエン酸またはそのエステルの製造方法
DE4200670C2 (de) * 1992-01-14 1994-06-23 Achenbach Buschhuetten Gmbh Anlage zur Entsorgung von bei der mechanischen Walzölfiltration anfallendem ölhaltigem Filterkuchen und Rückgewinnung des Walzöls
WO1993022022A1 (fr) * 1992-04-29 1993-11-11 Institut Français Du Petrole Procede et dispositif de fractionnement d'un melange en lit mobile simule en presence d'un gaz comprime, d'un fluide supercritique ou d'un liquide subcritique
FR2694208B1 (fr) * 1992-07-30 1994-09-23 Separex Sa Procédé et dispositif industriels de fractionnement de mélanges de composants par chromatographie.
FR2690630B1 (fr) * 1992-04-29 1994-07-22 Separex Sa Procede et dispositif de fractionnement de melanges de composants par voie chromatographique a l'aide d'un eluant a pression supercritique.
JP3614177B2 (ja) * 1992-07-21 2005-01-26 日本水産株式会社 高純度ドコサヘキサエン酸またはそのエステルの 製造方法

Also Published As

Publication number Publication date
CA2159823A1 (en) 1994-11-10
CA2159823C (en) 2004-08-31
DE69401506T2 (de) 1997-09-11
ES2097047T3 (es) 1997-03-16
JPH08512336A (ja) 1996-12-24
AU6691794A (en) 1994-11-21
DK0697034T3 (da) 1997-07-14
WO1994025552A1 (en) 1994-11-10
EP0697034A1 (de) 1996-02-21
EP0697034B1 (de) 1997-01-15
AU676910B2 (en) 1997-03-27
US5719302A (en) 1998-02-17
DE69401506D1 (de) 1997-02-27

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