ATE138938T1 - Sulfatiertes polysaccharid, dessen pharmazeutisch verträgliche salze, dessen herstellung und medikament, das dieses als wirksstoff enthält - Google Patents
Sulfatiertes polysaccharid, dessen pharmazeutisch verträgliche salze, dessen herstellung und medikament, das dieses als wirksstoff enthältInfo
- Publication number
- ATE138938T1 ATE138938T1 AT90902694T AT90902694T ATE138938T1 AT E138938 T1 ATE138938 T1 AT E138938T1 AT 90902694 T AT90902694 T AT 90902694T AT 90902694 T AT90902694 T AT 90902694T AT E138938 T1 ATE138938 T1 AT E138938T1
- Authority
- AT
- Austria
- Prior art keywords
- reaction
- sulfated polysaccharide
- pharmaceutically acceptable
- active ingredient
- acceptable salts
- Prior art date
Links
- 150000004676 glycans Chemical class 0.000 title abstract 3
- 229920001282 polysaccharide Polymers 0.000 title abstract 3
- 239000005017 polysaccharide Substances 0.000 title abstract 3
- 239000004480 active ingredient Substances 0.000 title abstract 2
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- QAOWNCQODCNURD-UHFFFAOYSA-N sulfuric acid Substances OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 abstract 2
- MSWZFWKMSRAUBD-GASJEMHNSA-N 2-amino-2-deoxy-D-galactopyranose Chemical compound N[C@H]1C(O)O[C@H](CO)[C@H](O)[C@@H]1O MSWZFWKMSRAUBD-GASJEMHNSA-N 0.000 abstract 1
- ZRKHIAJIHKHTDY-UHFFFAOYSA-N 5-methylbenzene-1,3-diol;hydrochloride Chemical compound Cl.CC1=CC(O)=CC(O)=C1 ZRKHIAJIHKHTDY-UHFFFAOYSA-N 0.000 abstract 1
- AEMOLEFTQBMNLQ-AQKNRBDQSA-N D-glucopyranuronic acid Chemical compound OC1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O AEMOLEFTQBMNLQ-AQKNRBDQSA-N 0.000 abstract 1
- SHZGCJCMOBCMKK-UHFFFAOYSA-N D-mannomethylose Natural products CC1OC(O)C(O)C(O)C1O SHZGCJCMOBCMKK-UHFFFAOYSA-N 0.000 abstract 1
- PNNNRSAQSRJVSB-SLPGGIOYSA-N Fucose Natural products C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)C=O PNNNRSAQSRJVSB-SLPGGIOYSA-N 0.000 abstract 1
- IAJILQKETJEXLJ-UHFFFAOYSA-N Galacturonsaeure Natural products O=CC(O)C(O)C(O)C(O)C(O)=O IAJILQKETJEXLJ-UHFFFAOYSA-N 0.000 abstract 1
- 241000251511 Holothuroidea Species 0.000 abstract 1
- SHZGCJCMOBCMKK-DHVFOXMCSA-N L-fucopyranose Chemical compound C[C@@H]1OC(O)[C@@H](O)[C@H](O)[C@@H]1O SHZGCJCMOBCMKK-DHVFOXMCSA-N 0.000 abstract 1
- 208000007536 Thrombosis Diseases 0.000 abstract 1
- PGWTYMLATMNCCZ-UHFFFAOYSA-M azure A Chemical compound [Cl-].C1=CC(N)=CC2=[S+]C3=CC(N(C)C)=CC=C3N=C21 PGWTYMLATMNCCZ-UHFFFAOYSA-M 0.000 abstract 1
- MSWZFWKMSRAUBD-UHFFFAOYSA-N beta-D-galactosamine Natural products NC1C(O)OC(CO)C(O)C1O MSWZFWKMSRAUBD-UHFFFAOYSA-N 0.000 abstract 1
- 230000015271 coagulation Effects 0.000 abstract 1
- 238000005345 coagulation Methods 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 229940097043 glucuronic acid Drugs 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Polymers & Plastics (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Materials Engineering (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Birds (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2829989 | 1989-02-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE138938T1 true ATE138938T1 (de) | 1996-06-15 |
Family
ID=12244736
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT90902694T ATE138938T1 (de) | 1989-02-06 | 1990-02-06 | Sulfatiertes polysaccharid, dessen pharmazeutisch verträgliche salze, dessen herstellung und medikament, das dieses als wirksstoff enthält |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP0408770B1 (de) |
| JP (1) | JP2714718B2 (de) |
| KR (1) | KR970000528B1 (de) |
| AT (1) | ATE138938T1 (de) |
| AU (1) | AU634521B2 (de) |
| CA (1) | CA2026992C (de) |
| DD (1) | DD297165A5 (de) |
| DE (1) | DE69027256T2 (de) |
| DK (1) | DK0408770T3 (de) |
| ES (1) | ES2087907T3 (de) |
| HU (1) | HU211988A9 (de) |
| WO (1) | WO1990008784A1 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0491027A (ja) * | 1990-08-02 | 1992-03-24 | Taiho Yakuhin Kogyo Kk | 抗ヒト免疫不全症ウィルス剤 |
| AU644464B2 (en) * | 1990-08-02 | 1993-12-09 | Taiho Pharmaceutical Co., Ltd. | Anti-human immunodeficiency virus agent |
| US6255296B1 (en) * | 1994-01-11 | 2001-07-03 | Endomatrix, Inc. | Composition and method for treating a patient susceptible to or suffering from a cardiovascular disorder or disease |
| CA2212458C (en) * | 1995-12-20 | 2001-08-28 | Taiho Pharmaceutical Co., Ltd. | Vascular intimal hyperplasia-inhibitory composition |
| US5876762A (en) * | 1996-08-05 | 1999-03-02 | Coastside Bio Resources | Process for obtaining medically active fractions from sea cucumbers |
| US6399105B1 (en) | 1999-01-20 | 2002-06-04 | Peter Donald Collin | Sea cucumber carotenoid lipid fraction products and methods of use |
| FR2797768B1 (fr) * | 1999-09-01 | 2003-06-13 | Ifremer | Utilisation d'un polysaccharide sulfate de bas poids moleculaire pour l'obtention d'un medicament actif contre la thrombose vasculaire |
| EP2980103B1 (de) | 2013-03-26 | 2020-11-04 | Jiuzhitang Co., Ltd. | Glykosaminoglykanderivat von niedrigem molekulargewicht, pharmazeutische zusammensetzung daraus, herstellungsverfahren dafür und verwendung davon |
| CN103788222B (zh) | 2014-01-08 | 2016-08-31 | 中国科学院昆明植物研究所 | Fuc3S4S取代的低聚糖胺聚糖及其制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3118588C2 (de) * | 1981-05-11 | 1983-07-07 | Luitpold-Werk, Chemisch-Pharmazeutische Fabrik, 8000 München | Verfahren zur Herstellung eines injizierbaren hochreinen Chondroitinpolysulfates, hiernach erhältliches Produkt und pharmazeutische Zusammensetzung |
| JPS63128001A (ja) * | 1986-11-19 | 1988-05-31 | Taiho Yakuhin Kogyo Kk | Ｆｇａｇ及びその塩、その製造方法並びにそれを含有する播種性血管内凝固症候群治療剤 |
| JP2785611B2 (ja) * | 1992-10-13 | 1998-08-13 | 宇部興産株式会社 | 被処理鋼板材コイルの先端口出し装置 |
-
1990
- 1990-02-06 ES ES90902694T patent/ES2087907T3/es not_active Expired - Lifetime
- 1990-02-06 JP JP2502725A patent/JP2714718B2/ja not_active Expired - Fee Related
- 1990-02-06 WO PCT/JP1990/000141 patent/WO1990008784A1/ja not_active Ceased
- 1990-02-06 AT AT90902694T patent/ATE138938T1/de not_active IP Right Cessation
- 1990-02-06 DK DK90902694.0T patent/DK0408770T3/da active
- 1990-02-06 AU AU50325/90A patent/AU634521B2/en not_active Ceased
- 1990-02-06 EP EP90902694A patent/EP0408770B1/de not_active Expired - Lifetime
- 1990-02-06 CA CA002026992A patent/CA2026992C/en not_active Expired - Fee Related
- 1990-02-06 DE DE69027256T patent/DE69027256T2/de not_active Expired - Fee Related
- 1990-08-06 DD DD90343252A patent/DD297165A5/de unknown
- 1990-10-06 KR KR1019900702212A patent/KR970000528B1/ko not_active Expired - Fee Related
-
1995
- 1995-06-30 HU HU95P/P00729P patent/HU211988A9/hu unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU634521B2 (en) | 1993-02-25 |
| HU211988A9 (en) | 1996-01-29 |
| DD297165A5 (de) | 1992-01-02 |
| CA2026992A1 (en) | 1990-08-07 |
| EP0408770A1 (de) | 1991-01-23 |
| EP0408770B1 (de) | 1996-06-05 |
| KR970000528B1 (ko) | 1997-01-13 |
| DK0408770T3 (da) | 1996-10-07 |
| EP0408770A4 (en) | 1992-03-18 |
| CA2026992C (en) | 1998-11-10 |
| DE69027256D1 (de) | 1996-07-11 |
| DE69027256T2 (de) | 1996-12-19 |
| WO1990008784A1 (fr) | 1990-08-09 |
| AU5032590A (en) | 1990-08-24 |
| ES2087907T3 (es) | 1996-08-01 |
| JP2714718B2 (ja) | 1998-02-16 |
| KR910700269A (ko) | 1991-03-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |