ATE126220T1 - 3-aryl-oxazolidinone-derivate, verfahren zu ihrer herstellung und ihre anwendung in der therapie. - Google Patents

3-aryl-oxazolidinone-derivate, verfahren zu ihrer herstellung und ihre anwendung in der therapie.

Info

Publication number
ATE126220T1
ATE126220T1 AT90402892T AT90402892T ATE126220T1 AT E126220 T1 ATE126220 T1 AT E126220T1 AT 90402892 T AT90402892 T AT 90402892T AT 90402892 T AT90402892 T AT 90402892T AT E126220 T1 ATE126220 T1 AT E126220T1
Authority
AT
Austria
Prior art keywords
group
alkyl
chain
groups
therapy
Prior art date
Application number
AT90402892T
Other languages
English (en)
Inventor
Francois-Xavier Jarreau
Vincenzo Rovei
Jean-Jacques Koenig
Alain Schoofs
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo filed Critical Synthelabo
Application granted granted Critical
Publication of ATE126220T1 publication Critical patent/ATE126220T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • C07D263/24—Oxygen atoms attached in position 2 with hydrocarbon radicals, substituted by oxygen atoms, attached to other ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Epidemiology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
AT90402892T 1989-10-17 1990-10-16 3-aryl-oxazolidinone-derivate, verfahren zu ihrer herstellung und ihre anwendung in der therapie. ATE126220T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8913555A FR2653017B1 (fr) 1989-10-17 1989-10-17 Derives d'aryl-3 oxazolidinone-2, leur procede de preparation et leur application en therapeutique.

Publications (1)

Publication Number Publication Date
ATE126220T1 true ATE126220T1 (de) 1995-08-15

Family

ID=9386480

Family Applications (2)

Application Number Title Priority Date Filing Date
AT90402891T ATE126792T1 (de) 1989-10-17 1990-10-16 3-aryl-oxazolidinone, verfahren zu ihrer herstellung und ihre anwendung in der therapie.
AT90402892T ATE126220T1 (de) 1989-10-17 1990-10-16 3-aryl-oxazolidinone-derivate, verfahren zu ihrer herstellung und ihre anwendung in der therapie.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT90402891T ATE126792T1 (de) 1989-10-17 1990-10-16 3-aryl-oxazolidinone, verfahren zu ihrer herstellung und ihre anwendung in der therapie.

Country Status (16)

Country Link
US (3) US5036091A (de)
EP (3) EP0428421A1 (de)
JP (3) JPH04502333A (de)
KR (3) KR0149508B1 (de)
AT (2) ATE126792T1 (de)
AU (3) AU637413B2 (de)
CA (3) CA2027715A1 (de)
DE (2) DE69021823T2 (de)
DK (1) DK0424244T3 (de)
ES (1) ES2078958T3 (de)
FR (1) FR2653017B1 (de)
GR (1) GR3017708T3 (de)
HK (1) HK1005591A1 (de)
NZ (3) NZ235728A (de)
WO (3) WO1991005774A1 (de)
ZA (3) ZA908284B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5196543A (en) * 1989-10-17 1993-03-23 Delalande S.A. 3-aryloxazolidinone derivatives, process for their preparation and their use in therapy
US5235063A (en) * 1989-10-17 1993-08-10 Delalande S.A. Process of preparing by condensation certain
FR2653017B1 (fr) * 1989-10-17 1995-05-05 Delalande Sa Derives d'aryl-3 oxazolidinone-2, leur procede de preparation et leur application en therapeutique.
FR2675504B1 (fr) * 1991-04-16 1995-01-27 Delalande Sa Derives d'aryl-3 oxazolidinone, leur procede de preparation et leur application en therapeutique.
TW286317B (de) * 1993-12-13 1996-09-21 Hoffmann La Roche
FR2715155B1 (fr) * 1994-01-19 1996-07-26 Mayoly Spindler Inhibiteurs de la monoamine oxydase B et leurs procédés de préparation.
FR2732679B1 (fr) * 1995-04-07 1997-04-30 Synthelabo Procede de preparation enzymatique d'un intermediaire de synthese de la befloxatone
ES2138346T3 (es) * 1995-06-02 2000-01-01 Sanofi Synthelabo Derivados de 5-(hidroximetil)oxazolidin-2-ona.
FR2734821B1 (fr) * 1995-06-02 1997-07-11 Synthelabo Derives de 5-methoxymethyl-3-(1,2-benzisoxazol-3-yl) oxazolidin-2-one, leur preparation et leur application en therapeutique
FR2734820B1 (fr) * 1995-06-02 1997-07-11 Synthelabo Derives de 3-(1,2-benzisoxazol-3-yl)oxazolidin-2-one, leur preparation et leur application en therapeutique
FR2737206B1 (fr) * 1995-07-24 1997-08-22 Synthelabo Derives d'oxazoloquinoleinone, leur preparation et leur application en therapeutique
FR2741072B1 (fr) * 1995-11-09 1997-12-12 Synthelabo Derives d'oxazolidin-2-one, leur preparation et leur application en therapeutique
FR2741071B1 (fr) * 1995-11-09 1997-12-12 Synthelabo Derives de 3-(benzofuran-5-yl)oxazolidin-2-one, leur preparation et leur application en therapeutique
US6642409B2 (en) 2000-01-27 2003-11-04 Central Glass Company, Limited Process for producing 4,4,4-trifluoro-3-hydroxybutyric acid derivatives
US6444813B2 (en) * 2000-02-02 2002-09-03 Pharmacia & Upjohn Company Linezolid-crystal form II
WO2002018354A1 (en) * 2000-08-31 2002-03-07 Abbott Laboratories Oxazolidinones and their use as antibacterial agents
EP2316468A1 (de) 2002-02-22 2011-05-04 Shire LLC Abgabesystem und Verfahren zum Schutz und zur Verabreichung von Dextroamphetamin

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU80081A1 (fr) * 1977-08-26 1979-05-15 Delalande Sa Nouvelles hydroxymethyl-5 oxazolidinones-2,leur procede de preparation et leur application therapeutique
FR2506769A2 (fr) * 1978-06-09 1982-12-03 Delalande Sa Para-((cyano-5 n pentyl-1) phenyl)-3 methoxymethyl-5 oxazolidinone-2, son procede de preparation et ses applications en therapeutique
FR2458547B2 (fr) * 1978-06-09 1986-05-16 Delalande Sa Nouvelles n-aryle azolones, leur procede de preparation et leur application en therapeutique
US4348393A (en) * 1978-06-09 1982-09-07 Delalande S.A. N-Aryl oxazolidinones, oxazolidinethiones, pyrrolidinones, pyrrolidines and thiazolidinones
CA1171865A (en) * 1980-06-04 1984-07-31 Alain Lacour N-aryl azolone derivatives, the process for preparing the same and their application in therapeutics
FR2608604B1 (fr) * 1986-12-19 1989-04-28 Delalande Sa Derives 5-hydroxyethyles de l'oxazolidinone-2, leurs procedes de preparation et leurs applications en therapeutique
FR2653017B1 (fr) * 1989-10-17 1995-05-05 Delalande Sa Derives d'aryl-3 oxazolidinone-2, leur procede de preparation et leur application en therapeutique.

Also Published As

Publication number Publication date
CA2027782A1 (en) 1991-04-18
AU6471590A (en) 1991-06-20
FR2653017A1 (fr) 1991-04-19
ZA908283B (en) 1991-08-28
AU6471390A (en) 1991-06-20
AU637150B2 (en) 1993-05-20
ATE126792T1 (de) 1995-09-15
ZA908284B (en) 1991-08-28
JPH04502335A (ja) 1992-04-23
EP0424244A1 (de) 1991-04-24
EP0424243A1 (de) 1991-04-24
US5036091A (en) 1991-07-30
US5171747A (en) 1992-12-15
ES2078958T3 (es) 1996-01-01
JPH07103114B2 (ja) 1995-11-08
KR920701176A (ko) 1992-08-11
CA2027783C (en) 1996-04-30
KR920701178A (ko) 1992-08-11
NZ235727A (en) 1992-04-28
CA2027782C (en) 1996-04-30
HK1005591A1 (en) 1999-01-15
AU6471490A (en) 1991-07-18
DE69021823T2 (de) 1996-07-11
DE69021498D1 (de) 1995-09-14
KR0149508B1 (ko) 1998-10-15
AU637413B2 (en) 1993-05-27
NZ235729A (en) 1992-05-26
NZ235728A (en) 1992-04-28
EP0428421A1 (de) 1991-05-22
KR920701177A (ko) 1992-08-11
FR2653017B1 (fr) 1995-05-05
EP0424243B1 (de) 1995-08-23
DE69021823D1 (de) 1995-09-28
WO1991005776A1 (fr) 1991-05-02
DE69021498T2 (de) 1996-03-28
US5036090A (en) 1991-07-30
WO1991005775A1 (fr) 1991-05-02
DK0424244T3 (da) 1996-01-02
WO1991005774A1 (fr) 1991-05-02
GR3017708T3 (en) 1996-01-31
AU635779B2 (en) 1993-04-01
JPH04502333A (ja) 1992-04-23
CA2027783A1 (en) 1991-04-18
EP0424244B1 (de) 1995-08-09
ZA908285B (en) 1991-08-28
JPH04502334A (ja) 1992-04-23
CA2027715A1 (en) 1991-04-18

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EEIH Change in the person of patent owner
EELA Cancelled due to lapse of time