ATE25383T1 - Indoloquinolizinderivate, verfahren zu ihrer herstellung und ihre therapeutische anwendung. - Google Patents
Indoloquinolizinderivate, verfahren zu ihrer herstellung und ihre therapeutische anwendung.Info
- Publication number
- ATE25383T1 ATE25383T1 AT81401811T AT81401811T ATE25383T1 AT E25383 T1 ATE25383 T1 AT E25383T1 AT 81401811 T AT81401811 T AT 81401811T AT 81401811 T AT81401811 T AT 81401811T AT E25383 T1 ATE25383 T1 AT E25383T1
- Authority
- AT
- Austria
- Prior art keywords
- hydrogen atom
- group
- indoloquinolizin
- derivatives
- production
- Prior art date
Links
- DBVVQINTNHWWGH-UHFFFAOYSA-N indolo[3,2-a]quinolizine Chemical class C1=CC=CC2=C3C4=CC=CC=C4N=C3C=CN21 DBVVQINTNHWWGH-UHFFFAOYSA-N 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 5
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 abstract 2
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000003287 optical effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP81401811A EP0079411B1 (de) | 1981-11-18 | 1981-11-18 | Indoloquinolizinderivate, Verfahren zu ihrer Herstellung und ihre therapeutische Anwendung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE25383T1 true ATE25383T1 (de) | 1987-02-15 |
Family
ID=8188566
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT81401811T ATE25383T1 (de) | 1981-11-18 | 1981-11-18 | Indoloquinolizinderivate, verfahren zu ihrer herstellung und ihre therapeutische anwendung. |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP0079411B1 (de) |
| AT (1) | ATE25383T1 (de) |
| DE (1) | DE3175900D1 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU191454B (en) * | 1984-10-05 | 1987-02-27 | Richter Gedeon Vegyeszeti Gyar Rt.,Hu | Process for producing amides of oktahydro-indolo/2,3-a/quinolyzin-1-yl-alkanecarboxylic acids and pharmaceutically acceptable acid additional salts thereof |
| HU194220B (en) * | 1985-04-19 | 1988-01-28 | Richter Gedeon Vegyeszet | Process for production of derivatives of 1,12 b disubstituated-octahydro-indolo /2,3-a/ quinolisine and medical compounds containing thereof |
| US4624954A (en) * | 1985-12-20 | 1986-11-25 | American Home Products Corporation | 6,7,8,9-tetrahydro-10-methylpyrido[1,2-a]indol-9-amines and derivatives thereof, useful for the treatment of cognitive impairments |
| US4665183A (en) * | 1985-12-20 | 1987-05-12 | American Home Products Corp. | Process for preparing 6,7,8,9-tetrahydro-10-methylpyrido[1,2-a]indol-9-amines and derivatives thereof useful for the treatment of cognitive impairments |
| FR2713643B1 (fr) * | 1993-12-14 | 1996-06-07 | Adir | Nouveaux analogues de l'éburnane, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent. |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1435573A (en) * | 1973-05-25 | 1976-05-12 | Wyeth John & Brother Ltd | Indoloquinolizines |
| ZA786426B (en) * | 1977-11-25 | 1979-10-31 | Scras | New indulo(2,3-a)quinolizidines,preparation and therapeutic use |
| US4181657A (en) * | 1978-07-14 | 1980-01-01 | Miles Laboratories, Inc. | 2-Aminooctahydroindolo[2,3-a]quinolizines useful in treating cardiovascular disorders |
-
1981
- 1981-11-18 AT AT81401811T patent/ATE25383T1/de not_active IP Right Cessation
- 1981-11-18 EP EP81401811A patent/EP0079411B1/de not_active Expired
- 1981-11-18 DE DE8181401811T patent/DE3175900D1/de not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| EP0079411B1 (de) | 1987-02-04 |
| DE3175900D1 (en) | 1987-03-12 |
| EP0079411A1 (de) | 1983-05-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |