ATE121632T1 - Verfahren zur herstellung einer radiopharmazeutischer zubereitung. - Google Patents

Verfahren zur herstellung einer radiopharmazeutischer zubereitung.

Info

Publication number
ATE121632T1
ATE121632T1 AT91118291T AT91118291T ATE121632T1 AT E121632 T1 ATE121632 T1 AT E121632T1 AT 91118291 T AT91118291 T AT 91118291T AT 91118291 T AT91118291 T AT 91118291T AT E121632 T1 ATE121632 T1 AT E121632T1
Authority
AT
Austria
Prior art keywords
water
nhch2co
reducing agent
producing
soluble
Prior art date
Application number
AT91118291T
Other languages
English (en)
Inventor
Susumu Kondo
Sakae Okano
Makoto Azuma
Original Assignee
Nihon Mediphysics Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nihon Mediphysics Co Ltd filed Critical Nihon Mediphysics Co Ltd
Application granted granted Critical
Publication of ATE121632T1 publication Critical patent/ATE121632T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT91118291T 1990-10-31 1991-10-26 Verfahren zur herstellung einer radiopharmazeutischer zubereitung. ATE121632T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2296563A JP2860157B2 (ja) 1990-10-31 1990-10-31 腎機能測定用の既放射能標識テクネチウムキレート注射剤の製造方法

Publications (1)

Publication Number Publication Date
ATE121632T1 true ATE121632T1 (de) 1995-05-15

Family

ID=17835168

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91118291T ATE121632T1 (de) 1990-10-31 1991-10-26 Verfahren zur herstellung einer radiopharmazeutischer zubereitung.

Country Status (10)

Country Link
US (1) US5245018A (de)
EP (1) EP0483704B1 (de)
JP (1) JP2860157B2 (de)
KR (1) KR0175305B1 (de)
AT (1) ATE121632T1 (de)
AU (1) AU638363B2 (de)
CA (1) CA2054263C (de)
DE (1) DE69109235T2 (de)
DK (1) DK0483704T3 (de)
ES (1) ES2074200T3 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5208007A (en) * 1988-11-22 1993-05-04 Board Of Regents Of The University Of Oklahoma Isotopic tracer composition and method for making and using same
US5443815A (en) * 1991-11-27 1995-08-22 Diatech, Inc. Technetium-99m labeled peptides for imaging
US5849261A (en) * 1991-02-08 1998-12-15 Diatide, Inc. Radiolabeled vasoactive intestinal peptides for diagnosis and therapy
US7238340B1 (en) 1991-11-27 2007-07-03 Cis Bio International Monoamine, diamide, thiol-containing metal chelating agents
US5783170A (en) * 1991-11-27 1998-07-21 Diatide, Inc. Peptide-metal chelate conjugates
DE69529988T2 (de) * 1994-05-02 2003-12-11 Diatide, Inc. Technetium-99m markierte bildformungsmittel
IL113610A0 (en) * 1994-06-03 1995-08-31 Immunomedics Inc A method of radiolabeling a protein, radiolabeled proteins prepared thereby and diagnostic kits containing the same
US5746996A (en) * 1994-06-03 1998-05-05 Immunomedics, Inc. Thiolation of peptides for radionuclide-based radiodetection and radiotherapy
US5986074A (en) * 1996-05-06 1999-11-16 Emory University Metal chelates as pharmaceutical imaging agents, processes of making such and uses thereof
US5924973A (en) * 1996-09-26 1999-07-20 The Trustees Of Columbia University In The City Of New York Method of treating a disease process in a luminal structure
KR101106533B1 (ko) * 2003-07-24 2012-01-20 브라코 이미징 에스.피.에이. 안정한 방사성의약 조성물 및 제조 방법
CA2555953A1 (en) * 2004-02-13 2005-09-01 Mallinckrodt Inc. Improvement in the ligand protection for mercaptoacetyl triglycine
GB0427392D0 (en) 2004-12-15 2005-01-19 Amersham Plc Stabilised 99mTc compositions
WO2008115337A1 (en) * 2007-03-19 2008-09-25 Mallinckrodt Inc. Sulfur-protected mercaptoacetylglycylglycylglycine
BRPI0800492B8 (pt) * 2008-01-31 2021-05-25 Univ Minas Gerais radiofármaco e sua composição farmacêutica para tratamento e diagnóstico de câncer
GB201402132D0 (en) * 2014-02-07 2014-03-26 South African Nuclear Energy A method of producing ethylenedicysteine deoxyglucosamine (ECDG) or a salt thereof and its application in a kit
WO2015200187A1 (en) 2014-06-27 2015-12-30 Reiley Pharmaceuticals, Inc. Conjugates derived from non-steroidal anti-inflammatory drugs and methods of use thereof in imaging
WO2016111834A1 (en) 2015-01-09 2016-07-14 Reiley Pharmaceuticals, Inc. Cox-2-targeting, platinum-containing conjugates and their use in the treatment of tumors and cancers

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3171920D1 (en) * 1981-09-16 1985-09-26 Nihon Mediphysics Co Ltd Radioactive diagnostic agent and its preparation
JPS5896031A (ja) * 1981-12-03 1983-06-07 Nippon Mejifuijitsukusu Kk 放射性診断剤およびその製造用組成物
US4510125A (en) * 1982-12-08 1985-04-09 Mallinckrodt, Inc. Process for making lyophilized radiographic imaging kit
US4638051A (en) * 1984-04-30 1987-01-20 The Johns Hopkins University Brain imaging radiopharmaceuticals
US4980147A (en) * 1984-06-25 1990-12-25 University Of Utah Research Foundation Radiolabeled technetium chelates for use in renal function determinations
DE3762624D1 (de) * 1986-05-28 1990-06-13 Mallinckrodt Inc Technetiumchelate fuer die bestimmung der nierenfunktion.
US4883862A (en) * 1988-04-13 1989-11-28 Albert Einstein College Of Medicine - Of Yeshiva University Mercaptosuccinyl glycyl-glycyl-glycine a complex thereof with Tc-99m, and methods of making the same
US4925650A (en) * 1988-11-16 1990-05-15 Mallinckrodt, Inc. Technetium -99m complex for examining the renal function
EP0427360B1 (de) * 1989-10-30 1994-06-15 Verein für Kernverfahrenstechnik und Analytik Rossendorf e.V. Kit (nichtradioaktive Vorstufe) zur Herstellung einer enantiomeren Form des Nierenfunktionsdiagnostikums Technetium-99m-Mercaptoacetyltriglycin (99m-Tc-MAG-3) und Verfahren zur Herstellung des Kits
ATE170757T1 (de) * 1990-04-17 1998-09-15 Mallinckrodt Medical Inc Methode und reagentien um technetium-99m-komplexe herzustellen

Also Published As

Publication number Publication date
JP2860157B2 (ja) 1999-02-24
JPH04169540A (ja) 1992-06-17
AU638363B2 (en) 1993-06-24
CA2054263A1 (en) 1992-05-01
AU8690991A (en) 1992-05-07
KR920007639A (ko) 1992-05-27
ES2074200T3 (es) 1995-09-01
CA2054263C (en) 2001-05-29
DE69109235D1 (de) 1995-06-01
DK0483704T3 (da) 1995-05-22
US5245018A (en) 1993-09-14
DE69109235T2 (de) 1995-09-28
EP0483704A1 (de) 1992-05-06
EP0483704B1 (de) 1995-04-26
KR0175305B1 (ko) 1999-02-18

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee