DK0483704T3 - Fremgangsmåde til fremstilling af et radiofarmaceutisk præparat - Google Patents

Fremgangsmåde til fremstilling af et radiofarmaceutisk præparat

Info

Publication number
DK0483704T3
DK0483704T3 DK91118291.3T DK91118291T DK0483704T3 DK 0483704 T3 DK0483704 T3 DK 0483704T3 DK 91118291 T DK91118291 T DK 91118291T DK 0483704 T3 DK0483704 T3 DK 0483704T3
Authority
DK
Denmark
Prior art keywords
water
radiopharmaceutical composition
nhch2co
reducing agent
preparation
Prior art date
Application number
DK91118291.3T
Other languages
English (en)
Inventor
Susumu Kondo
Sakae Okano
Makoto Azuma
Original Assignee
Nihon Mediphysics Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nihon Mediphysics Co Ltd filed Critical Nihon Mediphysics Co Ltd
Application granted granted Critical
Publication of DK0483704T3 publication Critical patent/DK0483704T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK91118291.3T 1990-10-31 1991-10-26 Fremgangsmåde til fremstilling af et radiofarmaceutisk præparat DK0483704T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2296563A JP2860157B2 (ja) 1990-10-31 1990-10-31 腎機能測定用の既放射能標識テクネチウムキレート注射剤の製造方法

Publications (1)

Publication Number Publication Date
DK0483704T3 true DK0483704T3 (da) 1995-05-22

Family

ID=17835168

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91118291.3T DK0483704T3 (da) 1990-10-31 1991-10-26 Fremgangsmåde til fremstilling af et radiofarmaceutisk præparat

Country Status (10)

Country Link
US (1) US5245018A (da)
EP (1) EP0483704B1 (da)
JP (1) JP2860157B2 (da)
KR (1) KR0175305B1 (da)
AT (1) ATE121632T1 (da)
AU (1) AU638363B2 (da)
CA (1) CA2054263C (da)
DE (1) DE69109235T2 (da)
DK (1) DK0483704T3 (da)
ES (1) ES2074200T3 (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5208007A (en) * 1988-11-22 1993-05-04 Board Of Regents Of The University Of Oklahoma Isotopic tracer composition and method for making and using same
US7238340B1 (en) 1991-11-27 2007-07-03 Cis Bio International Monoamine, diamide, thiol-containing metal chelating agents
US5443815A (en) * 1991-11-27 1995-08-22 Diatech, Inc. Technetium-99m labeled peptides for imaging
US5849261A (en) * 1991-02-08 1998-12-15 Diatide, Inc. Radiolabeled vasoactive intestinal peptides for diagnosis and therapy
US5783170A (en) * 1991-11-27 1998-07-21 Diatide, Inc. Peptide-metal chelate conjugates
DE69529988T2 (de) * 1994-05-02 2003-12-11 Diatide Inc Technetium-99m markierte bildformungsmittel
US5746996A (en) * 1994-06-03 1998-05-05 Immunomedics, Inc. Thiolation of peptides for radionuclide-based radiodetection and radiotherapy
IL113610A0 (en) * 1994-06-03 1995-08-31 Immunomedics Inc A method of radiolabeling a protein, radiolabeled proteins prepared thereby and diagnostic kits containing the same
US5986074A (en) * 1996-05-06 1999-11-16 Emory University Metal chelates as pharmaceutical imaging agents, processes of making such and uses thereof
US5924973A (en) 1996-09-26 1999-07-20 The Trustees Of Columbia University In The City Of New York Method of treating a disease process in a luminal structure
CA2526556C (en) * 2003-07-24 2012-09-25 Bracco Imaging S.P.A. Stable radiopharmaceutical compositions and methods for their preparation
JP2007537152A (ja) * 2004-02-13 2007-12-20 マリンクロッド・インコーポレイテッド メルカプトアセチルトリグリシン用のリガンド保護の改良
GB0427392D0 (en) 2004-12-15 2005-01-19 Amersham Plc Stabilised 99mTc compositions
WO2008115337A1 (en) * 2007-03-19 2008-09-25 Mallinckrodt Inc. Sulfur-protected mercaptoacetylglycylglycylglycine
BRPI0800492B8 (pt) * 2008-01-31 2021-05-25 Univ Minas Gerais radiofármaco e sua composição farmacêutica para tratamento e diagnóstico de câncer
GB201402132D0 (en) * 2014-02-07 2014-03-26 South African Nuclear Energy A method of producing ethylenedicysteine deoxyglucosamine (ECDG) or a salt thereof and its application in a kit
WO2015200187A1 (en) 2014-06-27 2015-12-30 Reiley Pharmaceuticals, Inc. Conjugates derived from non-steroidal anti-inflammatory drugs and methods of use thereof in imaging
EP3242688B1 (en) 2015-01-09 2020-01-29 Reiley Pharmaceuticals, Inc. Cox-2-targeting, platinum-containing conjugates and their use in the treatment of tumors and cancers

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3171920D1 (en) * 1981-09-16 1985-09-26 Nihon Mediphysics Co Ltd Radioactive diagnostic agent and its preparation
JPS5896031A (ja) * 1981-12-03 1983-06-07 Nippon Mejifuijitsukusu Kk 放射性診断剤およびその製造用組成物
US4510125A (en) * 1982-12-08 1985-04-09 Mallinckrodt, Inc. Process for making lyophilized radiographic imaging kit
US4638051A (en) * 1984-04-30 1987-01-20 The Johns Hopkins University Brain imaging radiopharmaceuticals
US4980147A (en) * 1984-06-25 1990-12-25 University Of Utah Research Foundation Radiolabeled technetium chelates for use in renal function determinations
ATE52516T1 (de) * 1986-05-28 1990-05-15 Mallinckrodt Inc Technetiumchelate fuer die bestimmung der nierenfunktion.
US4883862A (en) * 1988-04-13 1989-11-28 Albert Einstein College Of Medicine - Of Yeshiva University Mercaptosuccinyl glycyl-glycyl-glycine a complex thereof with Tc-99m, and methods of making the same
US4925650A (en) * 1988-11-16 1990-05-15 Mallinckrodt, Inc. Technetium -99m complex for examining the renal function
DE122005000028I2 (de) * 1989-10-30 2007-08-16 Rotop Pharmaka Ag Kit (nichtradioaktive Vorstufe) zur Herstellung einer enantiomeren Form des Nierenfunktionsdiagnostikums Technetium-99m-Mercaptoacetyltriglycin (99m-Tc-MAG-3) und Verfahren zur Herstellung des Kits
EP0639082B1 (en) * 1990-04-17 1998-09-09 Mallinckrodt Medical, Inc. Method and kit for preparing technetium-99m complexes

Also Published As

Publication number Publication date
CA2054263A1 (en) 1992-05-01
ES2074200T3 (es) 1995-09-01
EP0483704B1 (en) 1995-04-26
AU638363B2 (en) 1993-06-24
JP2860157B2 (ja) 1999-02-24
KR0175305B1 (ko) 1999-02-18
KR920007639A (ko) 1992-05-27
CA2054263C (en) 2001-05-29
JPH04169540A (ja) 1992-06-17
ATE121632T1 (de) 1995-05-15
DE69109235T2 (de) 1995-09-28
EP0483704A1 (en) 1992-05-06
US5245018A (en) 1993-09-14
AU8690991A (en) 1992-05-07
DE69109235D1 (de) 1995-06-01

Similar Documents

Publication Publication Date Title
DK0483704T3 (da) Fremgangsmåde til fremstilling af et radiofarmaceutisk præparat
DE3889956T2 (de) Metall-Radionuklid-markierte Proteine und Glykoproteine zur Diagnose und Therapie.
Anderson et al. Preparation, biodistribution and dosimetry of copper-64-labeled anti-colorectal carcinoma monoclonal antibody fragments 1A3-F (ab′) 2
US5053493A (en) Method for labeling antibodies with a metal ion
IE791203L (en) Radioactive scanning agents with hydroquinone as stabilizer
WO1992000759A3 (en) Stabilized therapeutic radiopharmaceutical complexes
US4851515A (en) Preparation of 99m Tc radiopharmaceuticals
Lin et al. Effect of reaction conditions on preparations of rhenium-188 hydroxyethylidene diphosphonate complexes
PH30975A (en) Radiopharmaceutical formulation, their method of administration and process of preparation.
US4560548A (en) Bone seeking Tc-99m complexes of phosphonate derivatives of bis(aminoalkyl)piperazine
SE7706126L (sv) Radioaktivt preparat
ATE179076T1 (de) Chelatbildner vom typ xn 1?s 1?o 1? für radioaktive isotope, deren metallkomplexe und ihre verwendung in diagnostik und therapie
Paik et al. Transchelation of 99mTc from low affinity sites to high affinity sites of antibody
EP1307239B1 (en) Radiopharmaceutical for diagnostic imaging containing a technetium-99m nitride heterocomplex
JPS52105222A (en) Stabilized alcoholic solution of reducible salt composition for making radioactive isotope indication scanning agent technetium 999m colloid for liver scanning and method of making same
JPS585887B2 (ja) ホウシヤセイイヤクヒン オヨビソノ セイゾウホウホウ
CA2051699A1 (en) 99mtc (iii) myocardial imaging agents that are effective in humans
US5177192A (en) Method for labeling antibodies with a metal ion
EP0176288B1 (en) Aminocarboxylic acid complexes for the treatment of calcific tumors
Finn et al. Technical challenges associated with the radiolabeling of monoclonal antibodies utilizing short-lived, positron emitting radionuclides
ATE4423T1 (de) 3-(3'-amino-2'-hydroxy-n-prop-1'-oxy)-6isopropylidenhydrazinopyridazine, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel.
JPS5396539A (en) Manufacture of flat heater
Shani et al. Labeling and comparative biodistribution of the monoclonal antibody KS14 in nude mice bearing human lung adenocarcinoma
CA1286086C (en) Preparation of __ tc radiopharmaceuticals
Kono et al. Complex Formed from 3-Hydroxy-4-formylpyridine, Glutamic Acid, and Technetium—A Possible Cholescintigraphic Agent