ATE170757T1 - Methode und reagentien um technetium-99m-komplexe herzustellen - Google Patents

Methode und reagentien um technetium-99m-komplexe herzustellen

Info

Publication number
ATE170757T1
ATE170757T1 AT91909080T AT91909080T ATE170757T1 AT E170757 T1 ATE170757 T1 AT E170757T1 AT 91909080 T AT91909080 T AT 91909080T AT 91909080 T AT91909080 T AT 91909080T AT E170757 T1 ATE170757 T1 AT E170757T1
Authority
AT
Austria
Prior art keywords
group
carboxy
alkyl group
hydrogen atom
pct
Prior art date
Application number
AT91909080T
Other languages
English (en)
Inventor
Alfons Verbruggen
Original Assignee
Mallinckrodt Medical Inc
Alfons Verbruggen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mallinckrodt Medical Inc, Alfons Verbruggen filed Critical Mallinckrodt Medical Inc
Application granted granted Critical
Publication of ATE170757T1 publication Critical patent/ATE170757T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT91909080T 1990-04-17 1991-04-10 Methode und reagentien um technetium-99m-komplexe herzustellen ATE170757T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP90200928 1990-04-17

Publications (1)

Publication Number Publication Date
ATE170757T1 true ATE170757T1 (de) 1998-09-15

Family

ID=8204992

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91909080T ATE170757T1 (de) 1990-04-17 1991-04-10 Methode und reagentien um technetium-99m-komplexe herzustellen

Country Status (8)

Country Link
US (1) US5268163A (de)
EP (1) EP0639082B1 (de)
JP (1) JP3005943B2 (de)
AT (1) ATE170757T1 (de)
AU (1) AU653153B2 (de)
CA (1) CA2080685A1 (de)
DE (1) DE69130182T2 (de)
WO (1) WO1991016076A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4965392A (en) * 1987-03-26 1990-10-23 Neorx Corporation Chelating compounds for metal-radionuclide labeled proteins
US5208007A (en) * 1988-11-22 1993-05-04 Board Of Regents Of The University Of Oklahoma Isotopic tracer composition and method for making and using same
JP2860157B2 (ja) * 1990-10-31 1999-02-24 日本メジフィジックス株式会社 腎機能測定用の既放射能標識テクネチウムキレート注射剤の製造方法
EP0618191A1 (de) * 1993-04-02 1994-10-05 AMERSHAM INTERNATIONAL plc Metall-chelatierende Verbindungen
JPH09500140A (ja) * 1993-07-19 1997-01-07 レゾリューション・ファーマスーティカルズ・インコーポレーテッド Ｎ▲下３▼ｓ立体配置を有するヒドラジノ型放射性核種キレート形成剤
US5858327A (en) * 1993-09-03 1999-01-12 Resolutions Pharmaceuticals, Inc. Hydrazino-type N2 S2 radionuclide chelating compounds
US5574140A (en) * 1993-09-03 1996-11-12 Resolution Pharmaceutical Inc. Hydrazino-type N2 S2 chelators
US5986074A (en) * 1996-05-06 1999-11-16 Emory University Metal chelates as pharmaceutical imaging agents, processes of making such and uses thereof
US5886142A (en) * 1997-05-20 1999-03-23 Thomas Jefferson University Radiolabeled thrombus imaging agents
NL1006164C2 (nl) * 1997-05-29 1998-12-01 Univ Leiden Antimicrobiële peptiden.
US7067111B1 (en) * 1999-10-25 2006-06-27 Board Of Regents, University Of Texas System Ethylenedicysteine (EC)-drug conjugates, compositions and methods for tissue specific disease imaging
US6841370B1 (en) 1999-11-18 2005-01-11 Cornell Research Foundation, Inc. Site-directed mutagenesis of Escherichia coli phytase
WO2001091807A2 (en) 2000-06-02 2001-12-06 Board Of Regents Ethylenedicysteine (ec)-drug conjugates
WO2004044227A2 (en) 2002-11-07 2004-05-27 Board Of Regents, The University Of Texas System Ethylenedicysteine (ec)-drug conjugates, compositions and methods for tissue specific disease imaging
US9050378B2 (en) 2003-12-10 2015-06-09 Board Of Regents, The University Of Texas System N2S2 chelate-targeting ligand conjugates
JP2008531755A (ja) * 2005-01-05 2008-08-14 ボード オブ リージェンツ， ザ ユニバーシティ オブ テキサス システム 二重画像化および放射線化学療法のためのコンジュゲート：組成物、製造および適応
US8758723B2 (en) * 2006-04-19 2014-06-24 The Board Of Regents Of The University Of Texas System Compositions and methods for cellular imaging and therapy
US10925977B2 (en) 2006-10-05 2021-02-23 Ceil>Point, LLC Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
GB201402132D0 (en) * 2014-02-07 2014-03-26 South African Nuclear Energy A method of producing ethylenedicysteine deoxyglucosamine (ECDG) or a salt thereof and its application in a kit

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4571430A (en) * 1982-11-08 1986-02-18 Medi-Physics, Inc. Homocysteine and homocysteinamide derivatives
US4638051A (en) * 1984-04-30 1987-01-20 The Johns Hopkins University Brain imaging radiopharmaceuticals
IT1176481B (it) * 1984-07-25 1987-08-18 Vittorio Pastro Nuovo tipo di aste di poligonazione per linee aeree di contatto per trazione elettrica
GB8426845D0 (en) * 1984-10-24 1984-11-28 Amersham Int Plc Complexes of technetium-99m
CA1243329A (en) * 1985-03-11 1988-10-18 Amersham Int Plc TECHNETIUM COMPLEXES WITH PROPYLENE-AMINE-OXIMES
ATE52516T1 (de) * 1986-05-28 1990-05-15 Mallinckrodt Inc Technetiumchelate fuer die bestimmung der nierenfunktion.
US4988496A (en) * 1988-05-31 1991-01-29 Neorx Corporation Metal radionuclide chelating compounds for improved chelation kinetics
US4925650A (en) * 1988-11-16 1990-05-15 Mallinckrodt, Inc. Technetium -99m complex for examining the renal function

Also Published As

Publication number Publication date
CA2080685A1 (en) 1991-10-18
WO1991016076A1 (en) 1991-10-31
JPH05505617A (ja) 1993-08-19
DE69130182D1 (de) 1998-10-15
EP0639082A1 (de) 1995-02-22
AU653153B2 (en) 1994-09-22
AU7799891A (en) 1991-11-11
JP3005943B2 (ja) 2000-02-07
EP0639082A4 (de) 1994-02-02
EP0639082B1 (de) 1998-09-09
US5268163A (en) 1993-12-07
DE69130182T2 (de) 1999-01-28

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