ATE113299T1 - Verbindungen. - Google Patents

Verbindungen.

Info

Publication number
ATE113299T1
ATE113299T1 AT89312898T AT89312898T ATE113299T1 AT E113299 T1 ATE113299 T1 AT E113299T1 AT 89312898 T AT89312898 T AT 89312898T AT 89312898 T AT89312898 T AT 89312898T AT E113299 T1 ATE113299 T1 AT E113299T1
Authority
AT
Austria
Prior art keywords
links
unit
2alkyl
4alkyl
aralkyl
Prior art date
Application number
AT89312898T
Other languages
English (en)
Inventor
Deirdre Mary Bernadette Hickey
Limited The Frythe Research
Albert Andrzej Jaxa-Chamiec
David Alston
Original Assignee
Smith Kline French Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith Kline French Lab filed Critical Smith Kline French Lab
Application granted granted Critical
Publication of ATE113299T1 publication Critical patent/ATE113299T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F265/00—Macromolecular compounds obtained by polymerising monomers on to polymers of unsaturated monocarboxylic acids or derivatives thereof as defined in group C08F20/00
    • C08F265/04—Macromolecular compounds obtained by polymerising monomers on to polymers of unsaturated monocarboxylic acids or derivatives thereof as defined in group C08F20/00 on to polymers of esters
    • C08F265/06—Polymerisation of acrylate or methacrylate esters on to polymers thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/03—Preparation of carboxylic acid esters by reacting an ester group with a hydroxy group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/62—Halogen-containing esters
    • C07C69/65—Halogen-containing esters of unsaturated acids
    • C07C69/653—Acrylic acid esters; Methacrylic acid esters; Haloacrylic acid esters; Halomethacrylic acid esters
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/44—Preparation of metal salts or ammonium salts

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Polymers & Plastics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Liquid Crystal (AREA)
  • Piezo-Electric Or Mechanical Vibrators, Or Delay Or Filter Circuits (AREA)
  • Electrically Driven Valve-Operating Means (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Manufacture Of Macromolecular Shaped Articles (AREA)
AT89312898T 1988-12-13 1989-12-11 Verbindungen. ATE113299T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888829088A GB8829088D0 (en) 1988-12-13 1988-12-13 Compounds

Publications (1)

Publication Number Publication Date
ATE113299T1 true ATE113299T1 (de) 1994-11-15

Family

ID=10648421

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89312898T ATE113299T1 (de) 1988-12-13 1989-12-11 Verbindungen.

Country Status (21)

Country Link
US (1) US5441731A (de)
EP (1) EP0373852B1 (de)
JP (1) JPH02212505A (de)
KR (1) KR900009725A (de)
CN (1) CN1044105A (de)
AT (1) ATE113299T1 (de)
AU (1) AU620183B2 (de)
CA (1) CA2004706A1 (de)
DE (1) DE68919061T2 (de)
DK (1) DK621289A (de)
ES (1) ES2063829T3 (de)
FI (1) FI895936A0 (de)
GB (1) GB8829088D0 (de)
HU (1) HU209397B (de)
IE (1) IE893966L (de)
MY (1) MY105079A (de)
NO (1) NO894995L (de)
NZ (1) NZ231728A (de)
PT (1) PT92531B (de)
ZA (1) ZA899467B (de)
ZW (1) ZW16589A1 (de)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2140449T3 (es) * 1992-01-14 2000-03-01 Hisamitsu Pharmaceutical Co Reductor del nivel de colesterol.
US5556619A (en) * 1992-08-20 1996-09-17 The Du Pont Merck Pharmaceutical Company Crosslinked polymeric ammonium salts
US5618530A (en) * 1994-06-10 1997-04-08 Geltex Pharmaceuticals, Inc. Hydrophobic amine polymer sequestrant and method of cholesterol depletion
US5703188A (en) * 1993-06-02 1997-12-30 Geltex Pharmaceuticals, Inc. Process for removing bile salts from a patient and compositions therefor
US5929184A (en) * 1993-06-02 1999-07-27 Geltex Pharmaceuticals, Inc. Hydrophilic nonamine-containing and amine-containing copolymers and their use as bile acid sequestrants
US5624963A (en) * 1993-06-02 1997-04-29 Geltex Pharmaceuticals, Inc. Process for removing bile salts from a patient and compositions therefor
US5900475A (en) * 1994-06-10 1999-05-04 Geltex Pharmaceuticals, Inc. Hydrophobic sequestrant for cholesterol depletion
US5607669A (en) * 1994-06-10 1997-03-04 Geltex Pharmaceuticals, Inc. Amine polymer sequestrant and method of cholesterol depletion
WO1994027620A1 (en) * 1993-06-02 1994-12-08 Geltex Pharmaceuticals, Inc. Compositions and process for removing bile salts
US6129910A (en) * 1993-06-02 2000-10-10 Geltex Pharmaceuticals, Inc. Water-insoluble noncrosslinked bile acid sequestrants
ZA95390B (en) * 1994-01-18 1996-07-18 Du Pont Crosslinked polymeric ammonium salts
US6395303B1 (en) 1996-06-10 2002-05-28 Edward Mendell Co., Inc. Process for preparing a directly compressible solid dosage form containing microcrystalline cellulose
US6471994B1 (en) 1995-01-09 2002-10-29 Edward Mendell Co., Inc. Pharmaceutical excipient having improved compressibility
IL116674A (en) * 1995-01-09 2003-05-29 Mendell Co Inc Edward Microcrystalline cellulose-based excipient having improved compressibility, pharmaceutical compositions containing the same and methods for the preparation of said excipient and of solid dosage form thereof
US5585115A (en) 1995-01-09 1996-12-17 Edward H. Mendell Co., Inc. Pharmaceutical excipient having improved compressability
US6936277B2 (en) * 1995-01-09 2005-08-30 J. Rettenmaier & Soehne Gmbh & Co. Kg Pharmaceutical excipient having improved compressibility
US5948438A (en) * 1995-01-09 1999-09-07 Edward Mendell Co., Inc. Pharmaceutical formulations having improved disintegration and/or absorptivity
US6203785B1 (en) 1996-12-30 2001-03-20 Geltex Pharmaceuticals, Inc. Poly(diallylamine)-based bile acid sequestrants
US5936003A (en) * 1997-03-03 1999-08-10 Dionex Corporation Hydrolytically stable resins for use in anion-exchange chromatography
US6423754B1 (en) 1997-06-18 2002-07-23 Geltex Pharmaceuticals, Inc. Method for treating hypercholesterolemia with polyallylamine polymers
US6726905B1 (en) 1997-11-05 2004-04-27 Genzyme Corporation Poly (diallylamines)-based phosphate binders
KR100381512B1 (ko) * 2000-09-21 2003-04-26 굿젠 주식회사 유전자 및 생물학적 활성 약물 전달용 양이온성 지질과이의 용도
US7335795B2 (en) 2004-03-22 2008-02-26 Ilypsa, Inc. Crosslinked amine polymers
US7767768B2 (en) 2003-11-03 2010-08-03 Ilypsa, Inc. Crosslinked amine polymers
US7608674B2 (en) 2003-11-03 2009-10-27 Ilypsa, Inc. Pharmaceutical compositions comprising cross-linked small molecule amine polymers
US7385012B2 (en) 2003-11-03 2008-06-10 Ilypsa, Inc. Polyamine polymers
US7449605B2 (en) 2003-11-03 2008-11-11 Ilypsa, Inc. Crosslinked amine polymers
US7459502B2 (en) 2003-11-03 2008-12-02 Ilypsa, Inc. Pharmaceutical compositions comprising crosslinked polyamine polymers
PT3219312T (pt) 2004-03-30 2019-03-01 Relypsa Inc Polímeros de ligação a ião e seus usos
WO2005097072A1 (en) 2004-03-30 2005-10-20 Ilypsa, Inc. Ion binding compositions
CN101321519A (zh) 2005-09-30 2008-12-10 伊立普萨公司 制备含有交联壳的核-壳型复合物的方法及其得到的核-壳型复合物
US8617609B2 (en) 2005-09-30 2013-12-31 Relypsa, Inc. Methods and compositions for selectively removing potassium ion from the gastrointestinal tract of a mammal
CN102202670B (zh) † 2008-08-22 2014-04-30 瑞立普萨公司 交联阳离子交换聚合物、组合物及在制备治疗高钾血症药物中的应用

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2843573A (en) * 1955-03-21 1958-07-15 Rohm & Haas New quaternary ammonium compounds in which the nitrogen atom carries an alkoxymethyl group
DE1065181B (de) * 1956-11-28 1959-09-10 Rohm S. Haas Company, Philadelphia, Pa. (V. St. A.) Verfahren zur Herstellung eines sowohl schwachbasischen anionenadsorbierenden, als auch stark-basischen, quaternäre Ammoniumgruppen enthaltenden Anionenaustauscherharzes
DE1233604B (de) * 1961-09-08 1967-02-02 Du Pont Verfahren zur Herstellung Aminoxydgruppen enthaltender Mischpolymerisate
BE756035A (fr) * 1969-09-12 1971-03-11 Inveresk Res Int Polymeres pontes
GB1309496A (en) * 1970-05-20 1973-03-14 Mitsubishi Gas Chemical Co Process for producing cationic synthetic latex
CS171962B1 (de) * 1974-02-01 1976-11-29
JPS50110482A (de) * 1974-02-13 1975-08-30
JPS52127995A (en) * 1976-04-19 1977-10-27 Johnson & Johnson Hydrophilic random copolymers composition and process for producing same
US4393145A (en) * 1979-05-01 1983-07-12 Etablissement Texcontor Anionic ion exchange resins with cholesterol-decreasing properties
JPS58154709A (ja) * 1982-03-09 1983-09-14 Kyoritsu Yuki Kogyo Kenkyusho:Kk カチオン性高吸水性樹脂の製法
DE3587419T2 (de) * 1985-01-07 1993-12-16 Rhone Poulenc Spec Chim Karboxylgruppenhaltige Polymere, Verfahren zu deren Herstellung und ihre Verwendung.
US4621120A (en) * 1985-04-01 1986-11-04 Eastman Kodak Company Polymeric antibacterial compositions
JPH075683B2 (ja) * 1986-09-09 1995-01-25 三菱レイヨン株式会社 帯電防止性に優れたメタクリル樹脂キヤスト板の製造方法
US4981936A (en) * 1989-04-14 1991-01-01 Polypure, Inc. Terpolymer of oxyalkyene acrylates, acrylamides and quaternary monomers

Also Published As

Publication number Publication date
HU896510D0 (en) 1990-02-28
ES2063829T3 (es) 1995-01-16
CN1044105A (zh) 1990-07-25
MY105079A (en) 1994-07-30
FI895936A0 (fi) 1989-12-12
CA2004706A1 (en) 1990-06-13
DE68919061D1 (de) 1994-12-01
EP0373852A2 (de) 1990-06-20
IE893966L (en) 1990-06-13
NO894995L (no) 1990-06-14
DK621289A (da) 1990-06-14
HUT53135A (en) 1990-09-28
AU620183B2 (en) 1992-02-13
PT92531A (pt) 1990-06-29
ZA899467B (en) 1991-07-31
NZ231728A (en) 1992-03-26
NO894995D0 (no) 1989-12-12
US5441731A (en) 1995-08-15
EP0373852B1 (de) 1994-10-26
JPH02212505A (ja) 1990-08-23
AU4608089A (en) 1990-06-21
DE68919061T2 (de) 1995-04-06
EP0373852A3 (de) 1991-12-27
ZW16589A1 (en) 1990-10-10
GB8829088D0 (en) 1989-01-25
DK621289D0 (da) 1989-12-08
KR900009725A (ko) 1990-07-05
HU209397B (en) 1994-05-30
PT92531B (pt) 1995-08-09

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee