ATE102071T1 - Entfernen von verfahrenschemikalien aus labilen biologischen gemischen durch hydrophobe austauschchromatographie. - Google Patents

Entfernen von verfahrenschemikalien aus labilen biologischen gemischen durch hydrophobe austauschchromatographie.

Info

Publication number
ATE102071T1
ATE102071T1 AT89118199T AT89118199T ATE102071T1 AT E102071 T1 ATE102071 T1 AT E102071T1 AT 89118199 T AT89118199 T AT 89118199T AT 89118199 T AT89118199 T AT 89118199T AT E102071 T1 ATE102071 T1 AT E102071T1
Authority
AT
Austria
Prior art keywords
laborable
removal
exchange chromatography
process chemicals
biological mixtures
Prior art date
Application number
AT89118199T
Other languages
English (en)
Inventor
Richard J Bonomo
Bernard Horowitz
Original Assignee
New York Blood Center Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22971853&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE102071(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by New York Blood Center Inc filed Critical New York Blood Center Inc
Application granted granted Critical
Publication of ATE102071T1 publication Critical patent/ATE102071T1/de

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/32—Bonded phase chromatography
    • B01D15/325—Reversed phase
    • B01D15/327—Reversed phase with hydrophobic interaction
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/16—Blood plasma; Blood serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0082—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances
    • A61L2/0088—Liquid substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
    • Y10T436/255—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.] including use of a solid sorbent, semipermeable membrane, or liquid extraction

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Anesthesiology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • External Artificial Organs (AREA)
  • Steroid Compounds (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Fats And Perfumes (AREA)
AT89118199T 1988-10-07 1989-09-30 Entfernen von verfahrenschemikalien aus labilen biologischen gemischen durch hydrophobe austauschchromatographie. ATE102071T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/256,332 US5094960A (en) 1988-10-07 1988-10-07 Removal of process chemicals from labile biological mixtures by hydrophobic interaction chromatography
EP89118199A EP0366946B1 (de) 1988-10-07 1989-09-30 Entfernen von Verfahrenschemikalien aus labilen biologischen Gemischen durch hydrophobe Austauschchromatographie

Publications (1)

Publication Number Publication Date
ATE102071T1 true ATE102071T1 (de) 1994-03-15

Family

ID=22971853

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89118199T ATE102071T1 (de) 1988-10-07 1989-09-30 Entfernen von verfahrenschemikalien aus labilen biologischen gemischen durch hydrophobe austauschchromatographie.

Country Status (9)

Country Link
US (1) US5094960A (de)
EP (1) EP0366946B1 (de)
JP (1) JP2799747B2 (de)
KR (1) KR970007941B1 (de)
AT (1) ATE102071T1 (de)
AU (1) AU621148B2 (de)
CA (1) CA1337052C (de)
DE (1) DE68913422T2 (de)
ES (1) ES2051951T3 (de)

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DE4008852A1 (de) * 1990-03-20 1991-09-26 Octapharma Ag Verfahren zur herstellung von nicht-infektioesem blutplasma
DE4125625C2 (de) * 1991-08-02 1999-12-02 Octapharma Ag Glarus Verfahren zur Herstellung von virusinaktivierten Immunglobulinlösungen
ATE180492T1 (de) * 1991-09-05 1999-06-15 Baxter Int Topischer fibrinogenkomplex
FR2690444B1 (fr) * 1992-04-22 1995-07-13 Rucheton Marcel Procede de preparation d'une solution d'albumine plasmatique purifiee.
AU667530B2 (en) * 1992-05-28 1996-03-28 New York Blood Center, Inc., The Removal of antibodies from blood-derived compositions while retaining coagulation factors
JPH06166634A (ja) * 1992-12-01 1994-06-14 Green Cross Corp:The プラスミノーゲン含有組成物の製造方法
DE4302163A1 (de) * 1993-01-27 1994-07-28 Thomae Gmbh Dr K Verfahren zur Reinigung von Proteinen und Peptiden
AU698154B2 (en) * 1993-06-23 1998-10-22 New York Blood Center, Inc., The System for viral inactivation of blood
US6319662B1 (en) * 1993-12-17 2001-11-20 Baxter International Inc. Method and apparatus for removing viral contaminants from a body fluid
JPH08257115A (ja) * 1995-03-20 1996-10-08 Kanegafuchi Chem Ind Co Ltd 腫瘍壊死因子の吸着剤および吸着除去方法
AU6267796A (en) * 1995-06-07 1996-12-30 Cerus Corporation Methods and devices for the removal of psoralens from blood products
US6544727B1 (en) * 1995-06-07 2003-04-08 Cerus Corporation Methods and devices for the removal of psoralens from blood products
DE19544297A1 (de) 1995-11-28 1997-06-05 Behringwerke Ag Verfahren zur Entfernung von aromatischen Verbindungen aus produkthaltigen Lösungen
US5747639A (en) * 1996-03-06 1998-05-05 Amgen Boulder Inc. Use of hydrophobic interaction chromatography to purify polyethylene glycols
US20020115585A1 (en) * 1996-06-07 2002-08-22 Hei Derek J. Method and devices for the removal of psoralens from blood products
US5811403A (en) 1996-09-30 1998-09-22 Vanderbilt University Polysaccharide toxin from Group B β-hemolytic Streptococcus (GBS) having improved purity
JP4630405B2 (ja) * 1997-01-06 2011-02-09 セラス コーポレーション 血液製剤から小有機化合物を減少させるための方法および装置
US20010018179A1 (en) 1998-01-06 2001-08-30 Derek J. Hei Batch devices for the reduction of compounds from biological compositions containing cells and methods of use
US20010009756A1 (en) 1998-01-06 2001-07-26 Derek Hei Flow devices for the reduction of compounds from biological compositions and methods of use
US5952235A (en) * 1997-04-14 1999-09-14 Case Western Reserve University Detection of teratogen exposure
US7611831B2 (en) * 1998-01-06 2009-11-03 Cerus Corporation Adsorbing pathogen-inactivating compounds with porous particles immobilized in a matrix
ES2224415T3 (es) 1998-01-06 2005-03-01 Cerus Corporation Metodos para inhibir desactivadores patogenos en materiales biologicos.
US6495140B1 (en) 1998-01-12 2002-12-17 Her Majesty In Right Of Canada As Represented By The Minister Of Agriculture And Agri-Food Canada Process for the isolation, recovery and purification of non-polar extractives
AT408613B (de) 1998-06-17 2002-01-25 Immuno Ag Pharmazeutisches faktor vii-präparat
DE19834053A1 (de) * 1998-07-29 2000-03-30 Centeon Pharma Gmbh Verfahren und Mittel zur Sanatisierung von durch Viren verursachten Kontaminationen
IL136552A (en) 2000-06-05 2005-05-17 Omrix Biopharmaceuticals Ltd Method for the inactivation of viruses by a solvent - detergent combination and by nanofiltration
ES2285427T3 (es) * 2003-02-13 2007-11-16 Octapharma Ag Procedimiento de preparacion de una solucion de albumina.
CN1748351B (zh) 2003-09-10 2010-11-03 爱信艾达株式会社 旋转电机制造装置以及旋转电机制造方法
US6881573B2 (en) * 2003-09-12 2005-04-19 Allan L. Louderback Augmented solvent/detergent method for inactivating enveloped and non-enveloped viruses
US20060234907A1 (en) * 2004-02-13 2006-10-19 Werner Gehringer Albumin solution and process for the production thereof
DE102004009400A1 (de) 2004-02-24 2005-09-08 Zlb Behring Gmbh Fibrinogen Reinigung
AU2005265960B8 (en) * 2004-06-29 2012-01-12 Reliance Life Sciences Pvt Ltd Process for improvement of virus-safe biological fluids
GB0423196D0 (en) * 2004-10-19 2004-11-24 Nat Blood Authority Method
PL1838355T3 (pl) * 2004-10-29 2014-01-31 Cerus Corp Ulepszone sposoby wygaszania dla procesu inaktywacji czerwonych krwinek
AU2005229674B2 (en) * 2004-11-18 2010-11-04 Kedrion Melville Inc. Low concentration solvent/detergent process of immuneglobulin with pre-treatment
EP1685852A1 (de) 2005-02-01 2006-08-02 Fondation pour la Recherche Diagnostique Set von Einwegbeuteln zur Virusinaktivierung von biologischen Fluids
WO2007054297A2 (de) * 2005-11-11 2007-05-18 Csl Behring Gmbh Verwendung hydrophober interaktionschromatographie zur virusabreichung
US8480889B2 (en) * 2006-04-27 2013-07-09 Agilent Technologies, Inc. Chromatographic stationary phase
AU2007268396B2 (en) 2006-05-30 2011-02-03 Lg Electronics Inc. Apparatus for preventing leakage of cooling air for refrigerator
US20080293623A1 (en) * 2007-04-30 2008-11-27 Nhs Blood And Transplant Enriched haptoglobin polymers for the treatment of disease
SG10201605663UA (en) 2008-04-09 2016-09-29 Cerus Corp Improved quenching methods for red blood cell pathogen inactivation
US20120039920A1 (en) * 2009-03-31 2012-02-16 Rasmussen Jerald K Hydrophobic monomers, hydrophobically-derivatized supports, and methods of making and using the same
EP2640834B1 (de) * 2010-11-16 2017-06-28 Cadila Healthcare Limited Neues verfahren zur reinigung von tpa
IL210162A0 (en) 2010-12-21 2011-03-31 Omrix Biopharmaceuticals Viral inactivated platelet extract, use and preparation thereof
US20130172536A1 (en) * 2011-08-16 2013-07-04 Shenzhen Weiguang Biological Products Co.,Ltd. Intravenous Cytomegalovirus Human Immune Globulin and Manufacturing Method Thereof
CH706420A1 (fr) * 2012-04-19 2013-10-31 Valerie Soulie Procédé d'inactivation virale d'un fluide biologique, dispositif et récipient pour la mise en œuvre d'un tel procédé.
WO2014097289A1 (en) 2012-12-20 2014-06-26 Omrix Biopharmaceuticals Ltd. Viral inactivated biological mixture
KR102317930B1 (ko) 2015-02-06 2021-10-29 광저우 바이오실 바이오테크 캄파니 리미티드 트롬빈의 제조 방법

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DE2750045A1 (de) * 1977-11-09 1979-05-10 Behringwerke Ag Verfahren zur entfernung von detergentien aus virusantigensuspensionen
US4464474A (en) * 1980-07-09 1984-08-07 Connaught Laboratories Limited Non-A, non-B hepatitis assay and vaccine
US4591505A (en) * 1982-04-14 1986-05-27 New York Blood Center, Inc. Process for inactivating hepatitis B virus
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US4677196A (en) * 1985-09-06 1987-06-30 International Minerals & Chemical Corp. Purification and activation of proteins from insoluble inclusion bodies
US4789545A (en) * 1986-03-31 1988-12-06 New York Blood Center, Inc. Removal of lipid soluble process chemicals from biological materials by extraction with naturally occurring oils or synthetic substitutes thereof
US4773458A (en) * 1986-10-08 1988-09-27 William Touzani Collapsible hollow articles with improved latching and dispensing configurations
US4894330A (en) * 1986-12-23 1990-01-16 Cetus Corporation Purification of recombinant beta-interferon incorporating RP-HPLC
US4909940A (en) * 1987-12-30 1990-03-20 New York Blood Center, Inc. Extraction of process chemicals from labile biological mixtures with organic alcohols or with halogenated hydrocarbons

Also Published As

Publication number Publication date
JP2799747B2 (ja) 1998-09-21
CA1337052C (en) 1995-09-19
KR900006010A (ko) 1990-05-07
DE68913422D1 (de) 1994-04-07
AU621148B2 (en) 1992-03-05
AU4155989A (en) 1990-09-13
EP0366946A1 (de) 1990-05-09
DE68913422T2 (de) 1994-06-01
US5094960A (en) 1992-03-10
ES2051951T3 (es) 1994-07-01
EP0366946B1 (de) 1994-03-02
KR970007941B1 (ko) 1997-05-19
JPH02198561A (ja) 1990-08-07

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time