ATA913578A - Verfahren zur o-metylierung von hydroxy- aporphinen - Google Patents
Verfahren zur o-metylierung von hydroxy- aporphinenInfo
- Publication number
- ATA913578A ATA913578A AT913578A AT913578A ATA913578A AT A913578 A ATA913578 A AT A913578A AT 913578 A AT913578 A AT 913578A AT 913578 A AT913578 A AT 913578A AT A913578 A ATA913578 A AT A913578A
- Authority
- AT
- Austria
- Prior art keywords
- metylation
- aporphines
- hydroxy
- hydroxy aporphines
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
- A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
- A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2757335A DE2757335C3 (de) | 1977-12-22 | 1977-12-22 | Verfahren zur O-Methylierung von Hydroxyaporphinen |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ATA913578A true ATA913578A (de) | 1980-10-15 |
| AT362535B AT362535B (de) | 1981-05-25 |
Family
ID=6026924
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT913578A AT362535B (de) | 1977-12-22 | 1978-12-21 | Verfahren zur o-methylierung von hydroxy- aporphinen |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US4309542A (de) |
| JP (1) | JPS54119474A (de) |
| AT (1) | AT362535B (de) |
| BE (1) | BE872843A (de) |
| CH (1) | CH645629A5 (de) |
| CS (1) | CS238601B2 (de) |
| DD (1) | DD141830A5 (de) |
| DE (1) | DE2757335C3 (de) |
| FI (1) | FI68222C (de) |
| FR (1) | FR2430942A1 (de) |
| GB (1) | GB2010841B (de) |
| HU (1) | HU177060B (de) |
| NL (1) | NL7812394A (de) |
| SU (1) | SU925249A3 (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3118521A1 (de) * | 1981-05-09 | 1982-12-02 | Gödecke AG, 1000 Berlin | Dibenzo(de,g)chinolin-derivate, verfahren zu deren herstellung und deren verwendung bei der bekaempfung von erkaeltungskrankheiten und allergien |
| US4795759A (en) * | 1985-07-27 | 1989-01-03 | Sandoz Ltd. | Use of dibenz(CD,F)indoles |
| US6210680B1 (en) | 1999-06-11 | 2001-04-03 | Univera Pharmaceuticals, Inc. | Method for the prevention and treatment of chronic venous insufficiency |
| TWI225397B (en) * | 2000-05-04 | 2004-12-21 | Nat Science Council | Uses of thaliporphine or its derivatives in treatment of cardiac diseases and preparation of the same |
| DE60119336T2 (de) * | 2000-08-23 | 2007-05-10 | Lotus Pharmaceutical Co., Ltd. | Verwendungen von thaliporphin oder seinen derivaten in der behandlung von herzkrankheiten und seine herstellung |
| JP2006527699A (ja) * | 2003-06-19 | 2006-12-07 | 美時化学製薬股▲ふん▼有限公司 | アポルフィン、及び、ケトンアポルフィン化合物とその用途 |
| CN1884265A (zh) * | 2005-06-20 | 2006-12-27 | 美时化学制药股份有限公司 | 治疗糖尿病的阿朴芬及次阿朴芬化合物 |
| WO2007134485A1 (en) * | 2006-05-22 | 2007-11-29 | Lotus Pharmaceutical Co., Ltd. | Aporphine and oxoaporphine compounds and pharmaceutical use thereof |
| TWI531369B (zh) * | 2014-05-30 | 2016-05-01 | 資元堂生物科技股份有限公司 | 阿朴啡生物鹼衍生物用於製備促進ａｍｐｋ活性的藥物之用途 |
| CN111196801B (zh) * | 2020-01-14 | 2022-10-14 | 中国药科大学 | 阿朴菲类生物碱衍生物及其制备方法与用途 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1100998A (en) * | 1912-05-06 | 1914-06-23 | Firm Of Mckesson & Robbins | Process of manufacuring alkyl-ethers of morphin. |
| GB1364318A (en) * | 1971-03-15 | 1974-08-21 | Bellon Labor Sa Roger | Laurotetanine derivatives |
| DE2337507A1 (de) * | 1973-07-24 | 1975-02-13 | Research Corp | Verfahren zur herstellung von aporphinen ueber neue zwischenprodukte |
| DE2625116C2 (de) * | 1976-06-04 | 1984-01-26 | Gödecke AG, 1000 Berlin | Verfahren zur Herstellung von 4-Hydroxy-aporphin-Derivaten |
-
1977
- 1977-12-22 DE DE2757335A patent/DE2757335C3/de not_active Expired
-
1978
- 1978-12-14 FR FR7835193A patent/FR2430942A1/fr active Granted
- 1978-12-18 BE BE192382A patent/BE872843A/xx not_active IP Right Cessation
- 1978-12-19 GB GB7849004A patent/GB2010841B/en not_active Expired
- 1978-12-19 US US05/971,143 patent/US4309542A/en not_active Expired - Lifetime
- 1978-12-20 DD DD78209943A patent/DD141830A5/de unknown
- 1978-12-21 FI FI783951A patent/FI68222C/fi not_active IP Right Cessation
- 1978-12-21 NL NL7812394A patent/NL7812394A/xx not_active Application Discontinuation
- 1978-12-21 JP JP15695578A patent/JPS54119474A/ja active Pending
- 1978-12-21 AT AT913578A patent/AT362535B/de not_active IP Right Cessation
- 1978-12-21 SU SU782700555A patent/SU925249A3/ru active
- 1978-12-21 HU HU78WA355A patent/HU177060B/hu unknown
- 1978-12-21 CH CH1305678A patent/CH645629A5/de not_active IP Right Cessation
- 1978-12-22 CS CS788857A patent/CS238601B2/cs unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US4309542A (en) | 1982-01-05 |
| CS238601B2 (en) | 1985-12-16 |
| FR2430942A1 (fr) | 1980-02-08 |
| FI68222C (fi) | 1985-08-12 |
| GB2010841A (en) | 1979-07-04 |
| FI783951A (fi) | 1979-06-23 |
| SU925249A3 (ru) | 1982-04-30 |
| DD141830A5 (de) | 1980-05-21 |
| BE872843A (fr) | 1979-04-17 |
| DE2757335A1 (de) | 1979-06-28 |
| FI68222B (fi) | 1985-04-30 |
| CH645629A5 (de) | 1984-10-15 |
| HU177060B (hu) | 1981-06-28 |
| DE2757335C3 (de) | 1982-03-25 |
| FR2430942B1 (de) | 1985-02-22 |
| NL7812394A (nl) | 1979-06-26 |
| JPS54119474A (en) | 1979-09-17 |
| GB2010841B (en) | 1982-08-18 |
| AT362535B (de) | 1981-05-25 |
| DE2757335B2 (de) | 1981-05-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ELJ | Ceased due to non-payment of the annual fee |