AT357280B - Verfahren zur herstellung von 17alpha- -alkinyl-androst-4-enderivaten - Google Patents

Verfahren zur herstellung von 17alpha- -alkinyl-androst-4-enderivaten

Info

Publication number
AT357280B
AT357280B AT121078A AT121078A AT357280B AT 357280 B AT357280 B AT 357280B AT 121078 A AT121078 A AT 121078A AT 121078 A AT121078 A AT 121078A AT 357280 B AT357280 B AT 357280B
Authority
AT
Austria
Prior art keywords
enderivaten
17alpha
androst
alkinyl
production
Prior art date
Application number
AT121078A
Other languages
English (en)
Other versions
ATA121078A (de
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR7705066A external-priority patent/FR2380781A1/fr
Priority claimed from FR7800405A external-priority patent/FR2414054A2/fr
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of ATA121078A publication Critical patent/ATA121078A/de
Application granted granted Critical
Publication of AT357280B publication Critical patent/AT357280B/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003Androstane derivatives
    • C07J1/0033Androstane derivatives substituted in position 17 alfa and 17 beta
    • C07J1/004Androstane derivatives substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
    • C07J1/0048Alkynyl derivatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT121078A 1977-02-22 1978-02-20 Verfahren zur herstellung von 17alpha- -alkinyl-androst-4-enderivaten AT357280B (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7705066A FR2380781A1 (fr) 1977-02-22 1977-02-22 Derives 17a-acetyleniques de l'androst 4-ene a titre de medicaments
FR7800405A FR2414054A2 (fr) 1978-01-09 1978-01-09 Nouveaux derives 17a-acetyleniques de l'androst 4-ene, leur procede de preparation et leur application comme medicaments

Publications (2)

Publication Number Publication Date
ATA121078A ATA121078A (de) 1979-11-15
AT357280B true AT357280B (de) 1980-06-25

Family

ID=26219859

Family Applications (1)

Application Number Title Priority Date Filing Date
AT121078A AT357280B (de) 1977-02-22 1978-02-20 Verfahren zur herstellung von 17alpha- -alkinyl-androst-4-enderivaten

Country Status (20)

Country Link
US (1) US4168306A (de)
JP (1) JPS53103462A (de)
AT (1) AT357280B (de)
AU (1) AU514875B2 (de)
CA (1) CA1114366A (de)
CH (1) CH633714A5 (de)
DE (1) DE2807611A1 (de)
DK (1) DK160559C (de)
ES (1) ES467158A1 (de)
GB (1) GB1598023A (de)
GR (1) GR71701B (de)
HU (1) HU175028B (de)
IE (1) IE46562B1 (de)
IL (1) IL54070A0 (de)
LU (1) LU79100A1 (de)
NL (1) NL7801919A (de)
OA (1) OA05890A (de)
PH (1) PH13909A (de)
PT (1) PT67685B (de)
SE (1) SE7801152L (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2430952A1 (fr) * 1978-07-13 1980-02-08 Roussel Uclaf Nouveaux derives acetyleniques de l'androst 4-ene, leur procede de preparation et leur application comme medicament
FR2433536A1 (fr) * 1978-08-16 1980-03-14 Roussel Uclaf Nouveaux derives de l'androst 4-ene, leur procede de preparation et leur application comme medicament
FR2468617A1 (fr) * 1979-10-26 1981-05-08 Roussel Uclaf Nouveaux derives acetyleniques chlores de l'androst-4-ene leur procede de preparation, et leur application a titre de medicament et les compositions pharmaceutiques les renfermant
CL2004000574A1 (es) * 2003-03-21 2005-02-11 Pharmacia Corp Sa Organizada B Proceso para preparar un compuesto 17-espirolactona o la sal de lactona abierta por carbonilacion del correspondiente 17-alquenil o alquinil derivado, los intermediarios que se usan y su proceso de obtencion.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3127314A (en) * 1964-03-31 Method of reducing hyperlipemia by
US2740798A (en) * 1953-05-25 1956-04-03 Searle & Co 11 beta-hydroxy-17-ethynyl testosterone and esters thereof
US2702811A (en) * 1953-08-28 1955-02-22 Searle & Co 19-nor-steroids
US3308025A (en) * 1963-04-30 1967-03-07 Roussel Uclaf Method for the treatment of estrogen deficiencies
GB1081494A (en) * 1965-09-14 1967-08-31 British Drug Houses Ltd 17ª‡-(alka-1',3'-diynyl)-steroids
US3793308A (en) * 1972-11-08 1974-02-19 Upjohn Co 4-spiro(cyclopropyl)androstenes and process for their production

Also Published As

Publication number Publication date
SE7801152L (sv) 1978-08-23
GB1598023A (en) 1981-09-16
HU175028B (hu) 1980-04-28
LU79100A1 (fr) 1978-09-28
JPS6249280B2 (de) 1987-10-19
NL7801919A (nl) 1978-08-24
ATA121078A (de) 1979-11-15
PH13909A (en) 1980-10-27
DK75778A (da) 1978-08-23
IL54070A0 (en) 1978-04-30
DE2807611C2 (de) 1989-04-20
ES467158A1 (es) 1978-11-16
PT67685A (fr) 1979-05-16
DK160559C (da) 1991-09-09
CH633714A5 (fr) 1982-12-31
PT67685B (fr) 1980-03-04
IE46562B1 (en) 1983-07-27
JPS53103462A (en) 1978-09-08
GR71701B (de) 1983-06-21
CA1114366A (fr) 1981-12-15
DK160559B (da) 1991-03-25
OA05890A (fr) 1981-05-31
US4168306A (en) 1979-09-18
IE780386L (en) 1978-08-22
AU3346878A (en) 1979-08-30
DE2807611A1 (de) 1978-08-24
AU514875B2 (en) 1981-03-05

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee