ES467158A1 - Un procedimiento de preparacion de derivados 17 alfa-aceti- lenicos del androst-4-eno. - Google Patents
Un procedimiento de preparacion de derivados 17 alfa-aceti- lenicos del androst-4-eno.Info
- Publication number
- ES467158A1 ES467158A1 ES78467158A ES467158A ES467158A1 ES 467158 A1 ES467158 A1 ES 467158A1 ES 78467158 A ES78467158 A ES 78467158A ES 467158 A ES467158 A ES 467158A ES 467158 A1 ES467158 A1 ES 467158A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- carbon atoms
- see formula
- compound
- alcohol radical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001875 compounds Chemical class 0.000 abstract 4
- 125000004432 carbon atom Chemical group C* 0.000 abstract 3
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 238000005903 acid hydrolysis reaction Methods 0.000 abstract 1
- -1 alkynyl magnesium halide Chemical class 0.000 abstract 1
- 150000001433 androst-4-enes Chemical class 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000000468 ketone group Chemical group 0.000 abstract 1
- 229910052749 magnesium Inorganic materials 0.000 abstract 1
- 239000011777 magnesium Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 150000002923 oximes Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0033—Androstane derivatives substituted in position 17 alfa and 17 beta
- C07J1/004—Androstane derivatives substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
- C07J1/0048—Alkynyl derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Rheumatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Pain & Pain Management (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7705066A FR2380781A1 (fr) | 1977-02-22 | 1977-02-22 | Derives 17a-acetyleniques de l'androst 4-ene a titre de medicaments |
| FR7800405A FR2414054A2 (fr) | 1978-01-09 | 1978-01-09 | Nouveaux derives 17a-acetyleniques de l'androst 4-ene, leur procede de preparation et leur application comme medicaments |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES467158A1 true ES467158A1 (es) | 1978-11-16 |
Family
ID=26219859
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES78467158A Expired ES467158A1 (es) | 1977-02-22 | 1978-02-21 | Un procedimiento de preparacion de derivados 17 alfa-aceti- lenicos del androst-4-eno. |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US4168306A (es) |
| JP (1) | JPS53103462A (es) |
| AT (1) | AT357280B (es) |
| AU (1) | AU514875B2 (es) |
| CA (1) | CA1114366A (es) |
| CH (1) | CH633714A5 (es) |
| DE (1) | DE2807611A1 (es) |
| DK (1) | DK160559C (es) |
| ES (1) | ES467158A1 (es) |
| GB (1) | GB1598023A (es) |
| GR (1) | GR71701B (es) |
| HU (1) | HU175028B (es) |
| IE (1) | IE46562B1 (es) |
| IL (1) | IL54070A0 (es) |
| LU (1) | LU79100A1 (es) |
| NL (1) | NL7801919A (es) |
| OA (1) | OA05890A (es) |
| PH (1) | PH13909A (es) |
| PT (1) | PT67685B (es) |
| SE (1) | SE7801152L (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2430952A1 (fr) * | 1978-07-13 | 1980-02-08 | Roussel Uclaf | Nouveaux derives acetyleniques de l'androst 4-ene, leur procede de preparation et leur application comme medicament |
| FR2433536A1 (fr) * | 1978-08-16 | 1980-03-14 | Roussel Uclaf | Nouveaux derives de l'androst 4-ene, leur procede de preparation et leur application comme medicament |
| FR2468617A1 (fr) * | 1979-10-26 | 1981-05-08 | Roussel Uclaf | Nouveaux derives acetyleniques chlores de l'androst-4-ene leur procede de preparation, et leur application a titre de medicament et les compositions pharmaceutiques les renfermant |
| CL2004000574A1 (es) * | 2003-03-21 | 2005-02-11 | Pharmacia Corp Sa Organizada B | Proceso para preparar un compuesto 17-espirolactona o la sal de lactona abierta por carbonilacion del correspondiente 17-alquenil o alquinil derivado, los intermediarios que se usan y su proceso de obtencion. |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3127314A (en) * | 1964-03-31 | Method of reducing hyperlipemia by | ||
| US2740798A (en) * | 1953-05-25 | 1956-04-03 | Searle & Co | 11 beta-hydroxy-17-ethynyl testosterone and esters thereof |
| US2702811A (en) * | 1953-08-28 | 1955-02-22 | Searle & Co | 19-nor-steroids |
| US3308025A (en) * | 1963-04-30 | 1967-03-07 | Roussel Uclaf | Method for the treatment of estrogen deficiencies |
| GB1081494A (en) * | 1965-09-14 | 1967-08-31 | British Drug Houses Ltd | 17ª-(alka-1',3'-diynyl)-steroids |
| US3793308A (en) * | 1972-11-08 | 1974-02-19 | Upjohn Co | 4-spiro(cyclopropyl)androstenes and process for their production |
-
1978
- 1978-01-31 SE SE7801152A patent/SE7801152L/xx unknown
- 1978-02-17 IL IL54070A patent/IL54070A0/xx not_active IP Right Cessation
- 1978-02-17 US US05/878,907 patent/US4168306A/en not_active Expired - Lifetime
- 1978-02-17 JP JP1666678A patent/JPS53103462A/ja active Granted
- 1978-02-17 OA OA56411A patent/OA05890A/xx unknown
- 1978-02-20 GR GR55501A patent/GR71701B/el unknown
- 1978-02-20 AT AT121078A patent/AT357280B/de not_active IP Right Cessation
- 1978-02-21 NL NL7801919A patent/NL7801919A/xx not_active Application Discontinuation
- 1978-02-21 ES ES78467158A patent/ES467158A1/es not_active Expired
- 1978-02-21 HU HU78RO964A patent/HU175028B/hu not_active IP Right Cessation
- 1978-02-21 PT PT67685A patent/PT67685B/pt unknown
- 1978-02-21 AU AU33468/78A patent/AU514875B2/en not_active Expired
- 1978-02-21 CA CA297,372A patent/CA1114366A/fr not_active Expired
- 1978-02-21 DK DK075778A patent/DK160559C/da not_active IP Right Cessation
- 1978-02-21 LU LU79100A patent/LU79100A1/xx unknown
- 1978-02-22 IE IE386/78A patent/IE46562B1/en not_active IP Right Cessation
- 1978-02-22 GB GB6984/78A patent/GB1598023A/en not_active Expired
- 1978-02-22 PH PH20808A patent/PH13909A/en unknown
- 1978-02-22 DE DE19782807611 patent/DE2807611A1/de active Granted
- 1978-02-22 CH CH193178A patent/CH633714A5/fr not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| US4168306A (en) | 1979-09-18 |
| JPS53103462A (en) | 1978-09-08 |
| AT357280B (de) | 1980-06-25 |
| IE780386L (en) | 1978-08-22 |
| DE2807611A1 (de) | 1978-08-24 |
| CA1114366A (fr) | 1981-12-15 |
| GR71701B (es) | 1983-06-21 |
| HU175028B (hu) | 1980-04-28 |
| ATA121078A (de) | 1979-11-15 |
| NL7801919A (nl) | 1978-08-24 |
| PT67685A (fr) | 1979-05-16 |
| AU514875B2 (en) | 1981-03-05 |
| DK75778A (da) | 1978-08-23 |
| JPS6249280B2 (es) | 1987-10-19 |
| IL54070A0 (en) | 1978-04-30 |
| OA05890A (fr) | 1981-05-31 |
| SE7801152L (sv) | 1978-08-23 |
| DK160559B (da) | 1991-03-25 |
| AU3346878A (en) | 1979-08-30 |
| DK160559C (da) | 1991-09-09 |
| PT67685B (fr) | 1980-03-04 |
| GB1598023A (en) | 1981-09-16 |
| IE46562B1 (en) | 1983-07-27 |
| CH633714A5 (fr) | 1982-12-31 |
| DE2807611C2 (es) | 1989-04-20 |
| PH13909A (en) | 1980-10-27 |
| LU79100A1 (fr) | 1978-09-28 |
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