ATA422281A - Verfahren zur herstellung des hydrochloridsalzes des h2-antagonisten n-(2-(((5-(dimethylamino)methyl)-2-furanyl)-methyl)-thio)-|thyl-n1-methy -2-nitro-1,1-aethendiamin - Google Patents

Verfahren zur herstellung des hydrochloridsalzes des h2-antagonisten n-(2-(((5-(dimethylamino)methyl)-2-furanyl)-methyl)-thio)-|thyl-n1-methy -2-nitro-1,1-aethendiamin

Info

Publication number
ATA422281A
ATA422281A AT0422281A AT422281A ATA422281A AT A422281 A ATA422281 A AT A422281A AT 0422281 A AT0422281 A AT 0422281A AT 422281 A AT422281 A AT 422281A AT A422281 A ATA422281 A AT A422281A
Authority
AT
Austria
Prior art keywords
methyl
aethendiamin
thyl
methy
furanyl
Prior art date
Application number
AT0422281A
Other languages
English (en)
Other versions
AT389696B (de
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10516407&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATA422281(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Priority to AT223188A priority Critical patent/AT407956B/de
Priority to AT109189A priority patent/AT402069B/de
Publication of ATA422281A publication Critical patent/ATA422281A/de
Application granted granted Critical
Publication of AT389696B publication Critical patent/AT389696B/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
AT0422281A 1980-10-01 1981-10-01 Verfahren zur herstellung des hydrochloridsalzes des h2-antagonisten n-(2-(((5-(dimethylamino)methyl)-2-furanyl)-methyl)-thio)-|thyl-n1-methy -2-nitro-1,1-aethendiamin AT389696B (de)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AT223188A AT407956B (de) 1980-10-01 1988-09-12 Verfahren zur herstellung eines arzneimittels
AT109189A AT402069B (de) 1980-10-01 1989-05-08 Eine neue kristallform des hydrochloridsalzes des h2-antagonisten n-(2-(((5-(dimethylamino)-methyl)-2-furanyl)-me hyl)-thio)-äthyl-n1-methyl-2-nitro- 1, 1-äthendiamin (ranitidin)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8031634 1980-10-01

Publications (2)

Publication Number Publication Date
ATA422281A true ATA422281A (de) 1989-06-15
AT389696B AT389696B (de) 1990-01-10

Family

ID=10516407

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0422281A AT389696B (de) 1980-10-01 1981-10-01 Verfahren zur herstellung des hydrochloridsalzes des h2-antagonisten n-(2-(((5-(dimethylamino)methyl)-2-furanyl)-methyl)-thio)-|thyl-n1-methy -2-nitro-1,1-aethendiamin

Country Status (29)

Country Link
US (2) US4521431A (de)
JP (1) JPS5791983A (de)
KR (1) KR870001431B1 (de)
AT (1) AT389696B (de)
AU (1) AU549119B2 (de)
BE (1) BE890574A (de)
CA (1) CA1202638A (de)
CH (1) CH652122A5 (de)
CZ (1) CZ280885B6 (de)
DE (1) DE3139134A1 (de)
DK (2) DK167794B1 (de)
ES (1) ES8301954A1 (de)
FR (1) FR2491067A1 (de)
GR (1) GR72499B (de)
HK (1) HK97985A (de)
IE (1) IE51604B1 (de)
IL (1) IL63968A (de)
IT (1) IT1143237B (de)
KE (1) KE3549A (de)
LU (1) LU83661A1 (de)
MY (1) MY8500747A (de)
NL (1) NL8104482A (de)
NZ (1) NZ198522A (de)
PH (2) PH19489A (de)
PT (1) PT73744B (de)
SE (1) SE453500B (de)
SK (1) SK403591A3 (de)
ZA (1) ZA816809B (de)
ZW (1) ZW24481A1 (de)

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US5338871A (en) * 1991-12-20 1994-08-16 Torcan Chemical Ltd. Preparation of form 1 ranitidine hydrochloride
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DE4341310A1 (de) * 1993-12-03 1995-06-08 Hexal Pharma Gmbh Tablette oder Kapsel mit einem Gehalt an stabilem Ranitidinhydrochlorid Form 1
US5407687A (en) * 1994-02-22 1995-04-18 Glaxo Inc. Ranitidine solid dosage form
EP0754182A1 (de) * 1994-04-08 1997-01-22 Brantford Chemicals Inc. Form 1 rantidinhydrochlorid mit erhöhter dichte
CA2120874E (en) * 1994-04-08 2002-01-08 Keshava Murthy Form of form 1 ranitidine
NZ282211A (en) 1994-04-15 1997-10-24 Upjohn Co Crystal form of piperazine compound; crystal forms of compound, identified by powder x-ray diffraction (xrd) spectrum
IN181698B (de) * 1994-05-13 1998-09-05 Ranbaxy Lab Ltd
NZ272054A (en) * 1994-05-13 1996-05-28 Ranbaxy Lab Ltd Process for producing form 1 ranitidine hydrochloride
IN181699B (de) * 1994-05-13 1998-09-05 Ranbaxy Lab Ltd
DK0766668T3 (da) * 1994-05-18 2002-10-28 Aventis Pharma Inc Fremgangsmåde til fremstilling af vandfrie og hydratformer af som antihistaminer anvendelige piperidinderivater, polymorfer og pseudo-morfer deraf
US20030045722A1 (en) * 1994-05-18 2003-03-06 Henton Daniel R. Processes for preparing anhydrous and hydrate forms of antihistaminic piperidine derivatives, polymorphs and pseudomorphs thereof
ES2122387T3 (es) 1994-06-24 1998-12-16 Ranbaxy Lab Ltd Procedimiento para la preparacion de la forma 1 del clorhidrato de ranitidina.
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US5538737A (en) * 1994-11-30 1996-07-23 Applied Analytical Industries, Inc. Oral compositions of H2 -antagonists
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AU1972097A (en) * 1996-03-25 1997-10-17 Hoechst Marion Roussel, Inc. Process for the preparation of form 1 ranitidine hydrochloride
ES2166205T3 (es) 1997-08-08 2002-04-01 Aventis Pharma Gmbh Forma cristalina de amida del acido n-(4-trifluorometilfenil)-5-metilisoxazol-4-carboxilico.
US6287693B1 (en) 1998-02-25 2001-09-11 John Claude Savoir Stable shaped particles of crystalline organic compounds
IT1317858B1 (it) * 2000-02-29 2003-07-15 Pharmexcel S R L Allomorfo del cloridrato dell'isomero z di derivato dialchilamminofurano, procedimento per la sua produzione e composizione
GB2357762B (en) * 2000-03-13 2002-01-30 Lundbeck & Co As H Crystalline base of citalopram
US20020183553A1 (en) * 2000-10-19 2002-12-05 Ben-Zion Dolitzky Crystalline venlafaxine base and novel polymorphs of venlafaxine hydrochloride, processes for preparing thereof
US20060173064A1 (en) * 2001-08-24 2006-08-03 Lippa Arnold S (-)-1-(3,4-Dichlorophenyl)-3-azabi cyclo[3.1.0]hexane, compositions thereof, and uses for treating alcohol-related disorders
US6569887B2 (en) * 2001-08-24 2003-05-27 Dov Pharmaceuticals Inc. (−)-1-(3,4-Dichlorophenyl)-3-azabicyclo[3.1.0]hexane, compositions thereof, and uses as a dopamine-reuptake
US7235655B2 (en) * 2002-03-22 2007-06-26 Pharmacia & Upjohn Company Processes to prepare eplerenone
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US20070043100A1 (en) 2005-08-16 2007-02-22 Hagen Eric J Novel polymorphs of azabicyclohexane
US20060100263A1 (en) * 2004-11-05 2006-05-11 Anthony Basile Antipyretic compositions and methods
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DE102005035891A1 (de) * 2005-07-30 2007-02-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg 8-(3-Amino-piperidin-1-yl)-xanthine, deren Herstellung und deren Verwendung als Arzneimittel
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US8138377B2 (en) 2006-11-07 2012-03-20 Dov Pharmaceutical, Inc. Arylbicyclo[3.1.0]hexylamines and methods and compositions for their preparation and use
US9133159B2 (en) 2007-06-06 2015-09-15 Neurovance, Inc. 1-heteroaryl-3-azabicyclo[3.1.0]hexanes, methods for their preparation and their use as medicaments
US20090069374A1 (en) * 2007-06-06 2009-03-12 Phil Skolnick Novel 1-Heteroaryl-3-Azabicyclo[3.1.0]Hexanes, Methods For Their Preparation And Their Use As Medicaments
TW201011043A (en) 2008-06-20 2010-03-16 Chugai Pharmaceutical Co Ltd Crystal of spiroketal derivatives and process for preparation of spiroketal derivatives
PT2727912T (pt) 2011-06-30 2017-07-25 Toray Industries Cristais de derivado de glicina e seu uso farmacêutico
US20140206740A1 (en) 2011-07-30 2014-07-24 Neurovance, Inc. Use Of (1R,5S)-(+)-(Napthalen-2-yl)-3-Azabicyclo[3.1.0]Hexane In The Treatment Of Conditions Affected By Monoamine Neurotransmitters
CN104817523B (zh) * 2015-05-26 2016-11-09 烟台市华文欣欣医药科技有限公司 一种治疗胃病的药物盐酸雷尼替丁化合物及其制备方法
CN105030694A (zh) * 2015-08-04 2015-11-11 青岛蓝盛洋医药生物科技有限责任公司 一种治疗胃溃疡的药物盐酸雷尼替丁组合物干混悬剂
CN104971053A (zh) * 2015-08-05 2015-10-14 青岛蓝盛洋医药生物科技有限责任公司 一种治疗消化系统疾病的药物盐酸雷尼替丁组合物片剂
CN105055331A (zh) * 2015-08-31 2015-11-18 青岛蓝盛洋医药生物科技有限责任公司 一种治疗消化性溃疡的药物盐酸雷尼替丁组合物颗粒剂
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Also Published As

Publication number Publication date
IL63968A (en) 1985-10-31
LU83661A1 (fr) 1983-06-08
IT8149407A0 (it) 1981-10-01
NZ198522A (en) 1985-07-12
ES505951A0 (es) 1983-01-01
FR2491067B1 (de) 1984-09-07
IT1143237B (it) 1986-10-22
AU549119B2 (en) 1986-01-16
PT73744B (en) 1983-10-31
KE3549A (en) 1985-08-16
JPH0443070B2 (de) 1992-07-15
FR2491067A1 (fr) 1982-04-02
PH21761A (en) 1988-02-18
KR870001431B1 (ko) 1987-08-06
AT389696B (de) 1990-01-10
CA1202638A (en) 1986-04-01
SK277922B6 (en) 1995-08-09
DE3139134C2 (de) 1990-04-19
DE3139134A1 (de) 1982-05-19
BE890574A (fr) 1982-04-01
DK167923B1 (da) 1994-01-03
CZ403591A3 (en) 1994-01-19
ES8301954A1 (es) 1983-01-01
MY8500747A (en) 1985-12-31
US4672133A (en) 1987-06-09
US4521431A (en) 1985-06-04
JPS5791983A (en) 1982-06-08
DK436281A (da) 1982-04-02
DK167794B1 (da) 1993-12-13
CH652122A5 (fr) 1985-10-31
HK97985A (en) 1985-12-13
KR830007070A (ko) 1983-10-14
ZW24481A1 (en) 1983-04-27
ZA816809B (en) 1983-05-25
GR72499B (de) 1983-11-15
NL8104482A (nl) 1982-05-03
IE51604B1 (en) 1987-01-21
IE812287L (en) 1982-04-01
CZ280885B6 (cs) 1996-04-17
AU7595581A (en) 1982-04-08
SE8105812L (sv) 1982-04-02
DK33792D0 (da) 1992-03-12
IL63968A0 (en) 1981-12-31
PH19489A (en) 1986-05-14
PT73744A (en) 1981-10-01
SK403591A3 (en) 1995-08-09
DK33792A (da) 1992-03-12
SE453500B (sv) 1988-02-08

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