ATA113378A - Verfahren zur herstellung von mefloquin - Google Patents

Verfahren zur herstellung von mefloquin

Info

Publication number
ATA113378A
ATA113378A AT113378A AT113378A ATA113378A AT A113378 A ATA113378 A AT A113378A AT 113378 A AT113378 A AT 113378A AT 113378 A AT113378 A AT 113378A AT A113378 A ATA113378 A AT A113378A
Authority
AT
Austria
Prior art keywords
mefloquin
producing
producing mefloquin
Prior art date
Application number
AT113378A
Other languages
English (en)
Other versions
AT358044B (de
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of ATA113378A publication Critical patent/ATA113378A/de
Application granted granted Critical
Publication of AT358044B publication Critical patent/AT358044B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/233—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/18—Halogen atoms or nitro radicals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
AT113378A 1977-02-17 1978-02-16 Verfahren zur herstellung von mefloquin AT358044B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US76981677A 1977-02-17 1977-02-17

Publications (2)

Publication Number Publication Date
ATA113378A true ATA113378A (de) 1980-01-15
AT358044B AT358044B (de) 1980-08-11

Family

ID=25086585

Family Applications (1)

Application Number Title Priority Date Filing Date
AT113378A AT358044B (de) 1977-02-17 1978-02-16 Verfahren zur herstellung von mefloquin

Country Status (9)

Country Link
JP (1) JPS53103478A (de)
AT (1) AT358044B (de)
BE (1) BE864002A (de)
CH (2) CH640530A5 (de)
DE (1) DE2806909A1 (de)
FR (1) FR2381044A1 (de)
GB (1) GB1594282A (de)
IT (1) IT1158450B (de)
NL (1) NL7801787A (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2940443A1 (de) * 1979-10-05 1981-04-16 Basf Ag, 6700 Ludwigshafen Verfahren zur herstellung von erythro-(alpha)-2-piperidyl-2,8-bis-(trifluormethyl)-4-chinolin-methanol
FR2485014A1 (fr) * 1980-06-20 1981-12-24 Pharmindustrie Nouveaux derives de (quinolyl-2, -3 ou -4)-1 (piperidyl ou pyrrolidinyl-2 ou -3)-2 ou -3 ethanone ou propanone, procedes pour leur preparation, et leur utilisation comme medicaments
US4507482A (en) * 1982-04-14 1985-03-26 Hoffmann-La Roche Inc. Purification of mefloquin hydrochloride
DK160499C (da) * 1982-09-10 1991-08-26 Hoffmann La Roche Fremgangsmaade til fremstilling af mefloquin og mellemprodukt til anvendelse herved
JPH0234129U (de) * 1989-05-25 1990-03-05
HUT54363A (en) * 1989-07-25 1991-02-28 Alkaloida Vegyeszeti Gyar Process for producing pyridyl-methyl-quinolin derivatives
GB9819382D0 (en) * 1998-09-04 1998-10-28 Cerebrus Ltd Chemical compounds I

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH590274A5 (de) * 1970-03-16 1977-07-29 Hoffmann La Roche
CH605916A5 (de) * 1973-12-07 1978-10-13 Hoffmann La Roche

Also Published As

Publication number Publication date
FR2381044B1 (de) 1983-06-10
CH640531A5 (en) 1984-01-13
NL7801787A (nl) 1978-08-21
CH640530A5 (en) 1984-01-13
IT1158450B (it) 1987-02-18
DE2806909A1 (de) 1978-08-24
IT7820331A0 (it) 1978-02-16
GB1594282A (en) 1981-07-30
FR2381044A1 (fr) 1978-09-15
JPS6257631B2 (de) 1987-12-02
DE2806909C2 (de) 1988-04-07
JPS53103478A (en) 1978-09-08
AT358044B (de) 1980-08-11
BE864002A (fr) 1978-08-16

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties