BE864002A - Procede pour la preparation de mefloquine - Google Patents

Procede pour la preparation de mefloquine

Info

Publication number
BE864002A
BE864002A BE185206A BE185206A BE864002A BE 864002 A BE864002 A BE 864002A BE 185206 A BE185206 A BE 185206A BE 185206 A BE185206 A BE 185206A BE 864002 A BE864002 A BE 864002A
Authority
BE
Belgium
Prior art keywords
mefloquine
preparation
Prior art date
Application number
BE185206A
Other languages
English (en)
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of BE864002A publication Critical patent/BE864002A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/233—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/18—Halogen atoms or nitro radicals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
BE185206A 1977-02-17 1978-02-16 Procede pour la preparation de mefloquine BE864002A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US76981677A 1977-02-17 1977-02-17

Publications (1)

Publication Number Publication Date
BE864002A true BE864002A (fr) 1978-08-16

Family

ID=25086585

Family Applications (1)

Application Number Title Priority Date Filing Date
BE185206A BE864002A (fr) 1977-02-17 1978-02-16 Procede pour la preparation de mefloquine

Country Status (9)

Country Link
JP (1) JPS53103478A (fr)
AT (1) AT358044B (fr)
BE (1) BE864002A (fr)
CH (2) CH640530A5 (fr)
DE (1) DE2806909A1 (fr)
FR (1) FR2381044A1 (fr)
GB (1) GB1594282A (fr)
IT (1) IT1158450B (fr)
NL (1) NL7801787A (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2940443A1 (de) * 1979-10-05 1981-04-16 Basf Ag, 6700 Ludwigshafen Verfahren zur herstellung von erythro-(alpha)-2-piperidyl-2,8-bis-(trifluormethyl)-4-chinolin-methanol
FR2485014A1 (fr) * 1980-06-20 1981-12-24 Pharmindustrie Nouveaux derives de (quinolyl-2, -3 ou -4)-1 (piperidyl ou pyrrolidinyl-2 ou -3)-2 ou -3 ethanone ou propanone, procedes pour leur preparation, et leur utilisation comme medicaments
US4507482A (en) * 1982-04-14 1985-03-26 Hoffmann-La Roche Inc. Purification of mefloquin hydrochloride
DK160499C (da) * 1982-09-10 1991-08-26 Hoffmann La Roche Fremgangsmaade til fremstilling af mefloquin og mellemprodukt til anvendelse herved
JPH0234129U (fr) * 1989-05-25 1990-03-05
HUT54363A (en) * 1989-07-25 1991-02-28 Alkaloida Vegyeszeti Gyar Process for producing pyridyl-methyl-quinolin derivatives
GB9819382D0 (en) * 1998-09-04 1998-10-28 Cerebrus Ltd Chemical compounds I

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH590275A5 (fr) * 1970-03-16 1977-07-29 Hoffmann La Roche
CH605916A5 (fr) * 1973-12-07 1978-10-13 Hoffmann La Roche

Also Published As

Publication number Publication date
IT7820331A0 (it) 1978-02-16
DE2806909C2 (fr) 1988-04-07
FR2381044A1 (fr) 1978-09-15
FR2381044B1 (fr) 1983-06-10
JPS53103478A (en) 1978-09-08
CH640530A5 (en) 1984-01-13
CH640531A5 (en) 1984-01-13
JPS6257631B2 (fr) 1987-12-02
NL7801787A (nl) 1978-08-21
AT358044B (de) 1980-08-11
GB1594282A (en) 1981-07-30
ATA113378A (de) 1980-01-15
DE2806909A1 (de) 1978-08-24
IT1158450B (it) 1987-02-18

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: F. HOFFMANN-LA ROCHE A.G.

Effective date: 19930228