ATA2198A - Verfahren zur isolierung eines diastereoisomerengemisches von cefpodoxim proxetil - Google Patents

Verfahren zur isolierung eines diastereoisomerengemisches von cefpodoxim proxetil

Info

Publication number
ATA2198A
ATA2198A AT0002198A AT2198A ATA2198A AT A2198 A ATA2198 A AT A2198A AT 0002198 A AT0002198 A AT 0002198A AT 2198 A AT2198 A AT 2198A AT A2198 A ATA2198 A AT A2198A
Authority
AT
Austria
Prior art keywords
isolating
diastereoisomer mixture
cefpodoxim
proxetil
cefpodoxim proxetil
Prior art date
Application number
AT0002198A
Other languages
English (en)
Other versions
AT413383B (de
Inventor
Julia Greil
Johannes Dr Ludescher
Klaus Dr Totschnig
Siegfried Wolf
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to AT0002198A priority Critical patent/AT413383B/de
Application filed by Sandoz Ag filed Critical Sandoz Ag
Priority to JP2000527547A priority patent/JP3911124B2/ja
Priority to PCT/EP1999/000057 priority patent/WO1999035149A1/en
Priority to DE69927943T priority patent/DE69927943T2/de
Priority to AT99906108T priority patent/ATE307817T1/de
Priority to KR10-2000-7007324A priority patent/KR100407584B1/ko
Priority to US09/582,896 priority patent/US6489470B1/en
Priority to AU26159/99A priority patent/AU2615999A/en
Priority to ES99906108T priority patent/ES2251826T3/es
Priority to CNB99802080XA priority patent/CN1142938C/zh
Priority to EP99906108A priority patent/EP1045852B1/de
Publication of ATA2198A publication Critical patent/ATA2198A/de
Application granted granted Critical
Publication of AT413383B publication Critical patent/AT413383B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/34—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
AT0002198A 1998-01-09 1998-01-09 Verfahren zur isolierung eines diastereoisomerengemisches von cefpodoxim proxetil AT413383B (de)

Priority Applications (11)

Application Number Priority Date Filing Date Title
AT0002198A AT413383B (de) 1998-01-09 1998-01-09 Verfahren zur isolierung eines diastereoisomerengemisches von cefpodoxim proxetil
PCT/EP1999/000057 WO1999035149A1 (en) 1998-01-09 1999-01-07 Process for the preparation of cefpodoxime proxetil diastereoisomers
DE69927943T DE69927943T2 (de) 1998-01-09 1999-01-07 Verfahren zur herstellung von cefpodoxim-proxetil diastereoisomeren
AT99906108T ATE307817T1 (de) 1998-01-09 1999-01-07 Verfahren zur herstellung von cefpodoxim-proxetil diastereoisomeren
JP2000527547A JP3911124B2 (ja) 1998-01-09 1999-01-07 セフポドキシムプロクセチルジアステレオ異性体の調製プロセス
KR10-2000-7007324A KR100407584B1 (ko) 1998-01-09 1999-01-07 세포독심 프록세틸 디아스테레오이성체의 제조 방법
US09/582,896 US6489470B1 (en) 1998-01-09 1999-01-07 Process for the preparation of cefpodoxime proxetil diastereoisomers
AU26159/99A AU2615999A (en) 1998-01-09 1999-01-07 Process for the preparation of cefpodoxime proxetil diastereoisomers
ES99906108T ES2251826T3 (es) 1998-01-09 1999-01-07 Procedimiento para la preparacion de diastereoisomeros de cefpodoxima proxetil.
CNB99802080XA CN1142938C (zh) 1998-01-09 1999-01-07 制备头孢丙肟酯非对映异构体的方法
EP99906108A EP1045852B1 (de) 1998-01-09 1999-01-07 Verfahren zur herstellung von cefpodoxim-proxetil diastereoisomeren

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT0002198A AT413383B (de) 1998-01-09 1998-01-09 Verfahren zur isolierung eines diastereoisomerengemisches von cefpodoxim proxetil

Publications (2)

Publication Number Publication Date
ATA2198A true ATA2198A (de) 2005-07-15
AT413383B AT413383B (de) 2006-02-15

Family

ID=3479444

Family Applications (2)

Application Number Title Priority Date Filing Date
AT0002198A AT413383B (de) 1998-01-09 1998-01-09 Verfahren zur isolierung eines diastereoisomerengemisches von cefpodoxim proxetil
AT99906108T ATE307817T1 (de) 1998-01-09 1999-01-07 Verfahren zur herstellung von cefpodoxim-proxetil diastereoisomeren

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT99906108T ATE307817T1 (de) 1998-01-09 1999-01-07 Verfahren zur herstellung von cefpodoxim-proxetil diastereoisomeren

Country Status (10)

Country Link
US (1) US6489470B1 (de)
EP (1) EP1045852B1 (de)
JP (1) JP3911124B2 (de)
KR (1) KR100407584B1 (de)
CN (1) CN1142938C (de)
AT (2) AT413383B (de)
AU (1) AU2615999A (de)
DE (1) DE69927943T2 (de)
ES (1) ES2251826T3 (de)
WO (1) WO1999035149A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT408226B (de) * 1999-05-05 2001-09-25 Biochemie Gmbh Kristalliner 7-(2-(2-formylaminothiazol-4-yl)-2
IN191496B (de) * 1999-07-30 2003-12-06 Ranbaxy Lab Ltd
KR100342944B1 (ko) * 1999-11-08 2002-07-02 민경윤 고순도 세프포독심 프록세틸의 제조방법
EP1373276A4 (de) 2001-02-27 2005-03-02 Ranbaxy Lab Ltd Verfahren zur herstellung von cefpodoxim-proxetil
AU2003282267A1 (en) * 2002-11-22 2004-06-18 Orchid Chemicals And Pharmaceuticals Ltd An improved process for the preparation of cefpodoxime proxetil
WO2004056834A1 (en) * 2002-12-20 2004-07-08 Lupin Limited A process for the preparation of cefpodoxime proxetil
AU2003303657A1 (en) * 2003-01-06 2004-07-29 Lupin Limited A process for the manufacture of cefpodoxime proxetil
MX2007014363A (es) * 2005-05-16 2009-04-15 Elan Pharma Int Ltd Composiciones de liberacion controlada y en forma de nanoparticulas que comprenden una cefalosporina.
JP5829952B2 (ja) * 2011-03-08 2015-12-09 株式会社ダイセル フォトレジスト製造用組成物の製造方法
EP2520578A1 (de) 2011-05-06 2012-11-07 Lupin Limited Verfahren zur Reinigung von Cephalosporinen
CN109232609B (zh) * 2018-09-27 2021-07-02 浙江普洛得邦制药有限公司 一种制备高纯度头孢泊肟酯的方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4409215A (en) 1979-11-19 1983-10-11 Fujisawa Pharmaceutical Co., Ltd. 7-Acylamino-3-substituted cephalosporanic acid derivatives and processes for the preparation thereof
EP0104671B1 (de) 1980-02-18 1990-05-23 Roussel-Uclaf Oximverbindungen von 3-Alkyloxy- oder 3-Alkylthiomethyl-7-amino-thiazolylacetamido-cephalosporansäure, ihre Herstellung, ihre Verwendung als Medikamente und sie enthaltende Präparate
US4486425A (en) 1980-09-30 1984-12-04 Sankyo Company Limited 7-[2-(2-Aminothiazol-4-yl)-2-(syn)-methoxyiminoacetamido]-3-methoxymethyl-3-cephem-4-carboxylates
JPS5896091A (ja) 1981-12-01 1983-06-07 Sankyo Co Ltd ３−アルコキシメチルセフアロスポリン類の製造法
EP0531875B1 (de) * 1991-09-07 2004-03-24 Aventis Pharma Deutschland GmbH Diastereomer des 3-Cephem-4-carbonsäure-1-(-isopropoxycarbonyloxy)ethylesters und Verfahren zu dessen Herstellung
AT408226B (de) * 1999-05-05 2001-09-25 Biochemie Gmbh Kristalliner 7-(2-(2-formylaminothiazol-4-yl)-2

Also Published As

Publication number Publication date
DE69927943T2 (de) 2006-07-27
ES2251826T3 (es) 2006-05-01
KR100407584B1 (ko) 2003-12-01
EP1045852A1 (de) 2000-10-25
DE69927943D1 (de) 2005-12-01
AU2615999A (en) 1999-07-26
US6489470B1 (en) 2002-12-03
JP2002500226A (ja) 2002-01-08
ATE307817T1 (de) 2005-11-15
KR20010024823A (ko) 2001-03-26
EP1045852B1 (de) 2005-10-26
WO1999035149A1 (en) 1999-07-15
AT413383B (de) 2006-02-15
JP3911124B2 (ja) 2007-05-09
CN1142938C (zh) 2004-03-24
CN1288466A (zh) 2001-03-21

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Legal Events

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