ATE307817T1 - Verfahren zur herstellung von cefpodoxim-proxetil diastereoisomeren - Google Patents

Verfahren zur herstellung von cefpodoxim-proxetil diastereoisomeren

Info

Publication number
ATE307817T1
ATE307817T1 AT99906108T AT99906108T ATE307817T1 AT E307817 T1 ATE307817 T1 AT E307817T1 AT 99906108 T AT99906108 T AT 99906108T AT 99906108 T AT99906108 T AT 99906108T AT E307817 T1 ATE307817 T1 AT E307817T1
Authority
AT
Austria
Prior art keywords
cefpodoxim
proxetil
diastereoisomers
producing
proxetil diastereoisomers
Prior art date
Application number
AT99906108T
Other languages
English (en)
Inventor
Julia Greil
Johannes Ludescher
Klaus Totschnig
Siegfried Wolf
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Application granted granted Critical
Publication of ATE307817T1 publication Critical patent/ATE307817T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/34—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
AT99906108T 1998-01-09 1999-01-07 Verfahren zur herstellung von cefpodoxim-proxetil diastereoisomeren ATE307817T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AT0002198A AT413383B (de) 1998-01-09 1998-01-09 Verfahren zur isolierung eines diastereoisomerengemisches von cefpodoxim proxetil
PCT/EP1999/000057 WO1999035149A1 (en) 1998-01-09 1999-01-07 Process for the preparation of cefpodoxime proxetil diastereoisomers
EP99906108A EP1045852B1 (de) 1998-01-09 1999-01-07 Verfahren zur herstellung von cefpodoxim-proxetil diastereoisomeren

Publications (1)

Publication Number Publication Date
ATE307817T1 true ATE307817T1 (de) 2005-11-15

Family

ID=3479444

Family Applications (2)

Application Number Title Priority Date Filing Date
AT0002198A AT413383B (de) 1998-01-09 1998-01-09 Verfahren zur isolierung eines diastereoisomerengemisches von cefpodoxim proxetil
AT99906108T ATE307817T1 (de) 1998-01-09 1999-01-07 Verfahren zur herstellung von cefpodoxim-proxetil diastereoisomeren

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT0002198A AT413383B (de) 1998-01-09 1998-01-09 Verfahren zur isolierung eines diastereoisomerengemisches von cefpodoxim proxetil

Country Status (10)

Country Link
US (1) US6489470B1 (de)
EP (1) EP1045852B1 (de)
JP (1) JP3911124B2 (de)
KR (1) KR100407584B1 (de)
CN (1) CN1142938C (de)
AT (2) AT413383B (de)
AU (1) AU2615999A (de)
DE (1) DE69927943T2 (de)
ES (1) ES2251826T3 (de)
WO (1) WO1999035149A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT408226B (de) * 1999-05-05 2001-09-25 Biochemie Gmbh Kristalliner 7-(2-(2-formylaminothiazol-4-yl)-2
IN191496B (de) * 1999-07-30 2003-12-06 Ranbaxy Lab Ltd
WO2002068429A1 (en) 2001-02-27 2002-09-06 Ranbaxy Laboratories Limited Process for the preparation of cefpodoxime proxetil
AU2003282267A1 (en) * 2002-11-22 2004-06-18 Orchid Chemicals And Pharmaceuticals Ltd An improved process for the preparation of cefpodoxime proxetil
DE60222945T2 (de) * 2002-12-20 2008-02-07 Lupin Ltd., Mumbai Verfahren zur herstellung von cefpodoxim-proxetil
WO2004060896A1 (en) * 2003-01-06 2004-07-22 Lupin Limited A process for the manufacture of cefpodoxime proxetil
BRPI0614080A2 (pt) * 2005-05-16 2017-07-25 Elan Pharma Int Ltd Composição e método para a preparação de uma cefalosporina nanoparticulada, para o tratamento de doença bacteriana e para a prevenção e/ou tratamento de osteoporose
TWI575311B (zh) * 2011-03-08 2017-03-21 大賽璐股份有限公司 光阻製造用溶劑或溶劑組成物
EP2520578A1 (de) 2011-05-06 2012-11-07 Lupin Limited Verfahren zur Reinigung von Cephalosporinen
CN109232609B (zh) * 2018-09-27 2021-07-02 浙江普洛得邦制药有限公司 一种制备高纯度头孢泊肟酯的方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4409215A (en) 1979-11-19 1983-10-11 Fujisawa Pharmaceutical Co., Ltd. 7-Acylamino-3-substituted cephalosporanic acid derivatives and processes for the preparation thereof
EP0076528B1 (de) 1980-02-18 1990-05-23 Roussel-Uclaf Oximderivate von 3-alkyloxy oder 3-alkylthiomethyl-7-amino thiazolylacetamidocephalosporansaure und ihre Herstellung
US4486425A (en) 1980-09-30 1984-12-04 Sankyo Company Limited 7-[2-(2-Aminothiazol-4-yl)-2-(syn)-methoxyiminoacetamido]-3-methoxymethyl-3-cephem-4-carboxylates
JPS5896091A (ja) 1981-12-01 1983-06-07 Sankyo Co Ltd ３−アルコキシメチルセフアロスポリン類の製造法
DE59209994D1 (de) * 1991-09-07 2004-04-29 Aventis Pharma Gmbh Diastereomer des 3-Cephem-4-carbonsäure-1-(-isopropoxycarbonyloxy)ethylesters und Verfahren zu dessen Herstellung
AT408226B (de) * 1999-05-05 2001-09-25 Biochemie Gmbh Kristalliner 7-(2-(2-formylaminothiazol-4-yl)-2

Also Published As

Publication number Publication date
CN1142938C (zh) 2004-03-24
KR100407584B1 (ko) 2003-12-01
DE69927943D1 (de) 2005-12-01
EP1045852B1 (de) 2005-10-26
JP2002500226A (ja) 2002-01-08
AU2615999A (en) 1999-07-26
EP1045852A1 (de) 2000-10-25
KR20010024823A (ko) 2001-03-26
ATA2198A (de) 2005-07-15
US6489470B1 (en) 2002-12-03
ES2251826T3 (es) 2006-05-01
DE69927943T2 (de) 2006-07-27
WO1999035149A1 (en) 1999-07-15
AT413383B (de) 2006-02-15
JP3911124B2 (ja) 2007-05-09
CN1288466A (zh) 2001-03-21

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Legal Events

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