AT394721B - Verfahren zur herstellung neuer chinazolinonverbindungen - Google Patents
Verfahren zur herstellung neuer chinazolinonverbindungen Download PDFInfo
- Publication number
- AT394721B AT394721B AT215987A AT215987A AT394721B AT 394721 B AT394721 B AT 394721B AT 215987 A AT215987 A AT 215987A AT 215987 A AT215987 A AT 215987A AT 394721 B AT394721 B AT 394721B
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- AT
- Austria
- Prior art keywords
- hydrogen
- compounds
- methyl
- alkyl
- formula
- Prior art date
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- 150000001875 compounds Chemical class 0.000 title claims description 63
- 238000004519 manufacturing process Methods 0.000 title claims description 7
- 229910052739 hydrogen Inorganic materials 0.000 claims description 36
- 239000001257 hydrogen Substances 0.000 claims description 36
- -1 methylenedioxy Chemical group 0.000 claims description 36
- 150000002431 hydrogen Chemical class 0.000 claims description 26
- 125000000217 alkyl group Chemical group 0.000 claims description 23
- 150000003839 salts Chemical class 0.000 claims description 21
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims description 20
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- 229910052801 chlorine Inorganic materials 0.000 claims description 19
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims description 16
- 229910052736 halogen Inorganic materials 0.000 claims description 14
- 150000002367 halogens Chemical class 0.000 claims description 14
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- 238000000034 method Methods 0.000 claims description 13
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- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims description 8
- 125000004453 alkoxycarbonyl group Chemical group 0.000 claims description 8
- 239000007858 starting material Substances 0.000 claims description 8
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- 238000002360 preparation method Methods 0.000 claims description 6
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- 229910052759 nickel Inorganic materials 0.000 description 1
- PXHVJJICTQNCMI-UHFFFAOYSA-N nickel Substances [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 125000003884 phenylalkyl group Chemical group 0.000 description 1
- LFSXCDWNBUNEEM-UHFFFAOYSA-N phthalazine Chemical class C1=NN=CC2=CC=CC=C21 LFSXCDWNBUNEEM-UHFFFAOYSA-N 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 229910000027 potassium carbonate Inorganic materials 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 201000003004 ptosis Diseases 0.000 description 1
- 229960000948 quinine Drugs 0.000 description 1
- 125000002914 sec-butyl group Chemical group [H]C([H])([H])C([H])([H])C([H])(*)C([H])([H])[H] 0.000 description 1
- WXMKPNITSTVMEF-UHFFFAOYSA-M sodium benzoate Chemical compound [Na+].[O-]C(=O)C1=CC=CC=C1 WXMKPNITSTVMEF-UHFFFAOYSA-M 0.000 description 1
- 239000004299 sodium benzoate Substances 0.000 description 1
- 235000010234 sodium benzoate Nutrition 0.000 description 1
- 235000017557 sodium bicarbonate Nutrition 0.000 description 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 1
- 239000001509 sodium citrate Substances 0.000 description 1
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 1
- HYHCSLBZRBJJCH-UHFFFAOYSA-M sodium hydrosulfide Chemical compound [Na+].[SH-] HYHCSLBZRBJJCH-UHFFFAOYSA-M 0.000 description 1
- 235000019333 sodium laurylsulphate Nutrition 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 125000003003 spiro group Chemical group 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- 150000003548 thiazolidines Chemical class 0.000 description 1
- 230000008719 thickening Effects 0.000 description 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT201389A AT394722B (de) | 1986-08-29 | 1989-08-25 | Verfahren zur herstellung neuer chinazolinonverbindungen |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP20466386A JPS6360987A (ja) | 1986-08-29 | 1986-08-29 | キナゾリノン誘導体の製法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ATA215987A ATA215987A (de) | 1991-11-15 |
| AT394721B true AT394721B (de) | 1992-06-10 |
Family
ID=16494219
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT215987A AT394721B (de) | 1986-08-29 | 1987-08-27 | Verfahren zur herstellung neuer chinazolinonverbindungen |
Country Status (4)
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GR1000821B (el) * | 1988-11-22 | 1993-01-25 | Tanabe Seiyaku Co | Μεθοδος παραγωγης παραγωγων κιναζολινονης. |
| US8686011B2 (en) | 2004-05-24 | 2014-04-01 | Amgen Inc. | Inhibitors of 11-β-hydroxy steroid dehydrogenase type 1 |
| AR049344A1 (es) * | 2004-05-24 | 2006-07-19 | Amgen Inc | Inhibidores de la 11-beta-hidroxi esteroide deshidrogenasa de tipo 1 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0204534A2 (en) * | 1985-06-06 | 1986-12-10 | Tanabe Seiyaku Co., Ltd. | Quinazolinone compounds and processes for the preparation thereof |
-
1986
- 1986-08-29 JP JP20466386A patent/JPS6360987A/ja active Granted
-
1987
- 1987-08-26 CA CA000545406A patent/CA1300623C/en not_active Expired - Lifetime
- 1987-08-27 AT AT215987A patent/AT394721B/de not_active IP Right Cessation
- 1987-08-28 ES ES8702505A patent/ES2004991A6/es not_active Expired
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0204534A2 (en) * | 1985-06-06 | 1986-12-10 | Tanabe Seiyaku Co., Ltd. | Quinazolinone compounds and processes for the preparation thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| ATA215987A (de) | 1991-11-15 |
| CA1300623C (en) | 1992-05-12 |
| JPS6360987A (ja) | 1988-03-17 |
| ES2004991A6 (es) | 1989-02-16 |
| JPH0312067B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1991-02-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ELJ | Ceased due to non-payment of the annual fee | ||
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |