AT386824B - Verfahren zur herstellung von n-sulfanyl-3(2-guanidinothazol-4-yl-methylthio)-propionamid n - Google Patents

Verfahren zur herstellung von n-sulfanyl-3(2-guanidinothazol-4-yl-methylthio)-propionamid n

Info

Publication number
AT386824B
AT386824B AT0243486A AT243486A AT386824B AT 386824 B AT386824 B AT 386824B AT 0243486 A AT0243486 A AT 0243486A AT 243486 A AT243486 A AT 243486A AT 386824 B AT386824 B AT 386824B
Authority
AT
Austria
Prior art keywords
guanidinothazol
sulfanyl
propionamide
methylthio
producing
Prior art date
Application number
AT0243486A
Other languages
English (en)
Other versions
ATA243486A (de
Inventor
Peter Dipl Ing Bod
Kalman Dipl Ing Dr Harsanyi
Eva Dipl Ing Agai
Erik Dipl Ing Bogsch
Eva Dipl Ing Fekecs
Ferenc Dr Trischler
Gyoergy Dipl Ing Dr Domany
Istvan Dipl Ing Szabadkai
Bela Dipl Ing Dr Hegedues
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10963968&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AT386824(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of ATA243486A publication Critical patent/ATA243486A/de
Application granted granted Critical
Publication of AT386824B publication Critical patent/AT386824B/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38Nitrogen atoms
    • C07D277/44Acylated amino or imino radicals
    • C07D277/48Acylated amino or imino radicals by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof, e.g. carbonylguanidines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/28Radicals substituted by nitrogen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT0243486A 1985-09-11 1986-09-10 Verfahren zur herstellung von n-sulfanyl-3(2-guanidinothazol-4-yl-methylthio)-propionamid n AT386824B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU853424A HU194845B (en) 1985-09-11 1985-09-11 Process for production of n-sulphamil-3-/2-guanidintiazolil-4-methil-tio/-propion-amidin

Publications (2)

Publication Number Publication Date
ATA243486A ATA243486A (de) 1988-03-15
AT386824B true AT386824B (de) 1988-10-25

Family

ID=10963968

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0243486A AT386824B (de) 1985-09-11 1986-09-10 Verfahren zur herstellung von n-sulfanyl-3(2-guanidinothazol-4-yl-methylthio)-propionamid n

Country Status (22)

Country Link
US (1) US4835281A (de)
JP (1) JPH0645609B2 (de)
KR (1) KR910000237B1 (de)
CN (1) CN1013674B (de)
AR (1) AR240319A1 (de)
AT (1) AT386824B (de)
AU (1) AU587279B2 (de)
BE (1) BE905409A (de)
CA (1) CA1263120A (de)
DD (1) DD249479A5 (de)
DK (1) DK169920B1 (de)
ES (1) ES2001677A6 (de)
FI (1) FI86423C (de)
GB (1) GB2180237B (de)
GE (1) GEP19960471B (de)
GR (1) GR862308B (de)
HU (1) HU194845B (de)
NL (1) NL8602225A (de)
NO (1) NO163010C (de)
PT (1) PT83348B (de)
SE (1) SE8603797L (de)
SU (1) SU1450743A3 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU194845B (en) * 1985-09-11 1988-03-28 Richter Gedeon Vegyeszet Process for production of n-sulphamil-3-/2-guanidintiazolil-4-methil-tio/-propion-amidin
HU196775B (en) * 1986-08-05 1989-01-30 Richter Gedeon Vegyeszet Process for production of morfologically unique new modifications of famotidin and medical compositions containing such substances
IL86330A0 (en) * 1987-06-22 1988-11-15 Marga Investigacion Famotidine polymorphic forms and their preparation
US5856500A (en) * 1997-03-11 1999-01-05 Albemarle Corporation Synthesis of thiazole derivatives
US5731442A (en) * 1997-03-11 1998-03-24 Albemarle Corporation Synthesis of thiazole derivatives
CA2349575A1 (en) * 1998-11-17 2000-05-25 Nitromed, Inc. Nitrosated and nitrosylated h2 receptor antagonist compounds, compositions and methods of use
US20110143340A1 (en) * 2007-11-01 2011-06-16 Biocept, Inc. Non-invasive isolation of fetal nucleic acid

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES8506664A1 (es) * 1984-10-17 1985-08-01 Inke Sa Procedimiento para la obtencion de la (1-amino-3(((2-((diamino-metilen) amino)-4-tiazolil)metil)tio)propiliden)sulfamida
ES8506665A1 (es) * 1984-05-07 1985-08-01 Inke Sa Procedimiento para la obtencion de la 1-amino-3-2-diamino-metilen-amino-4-tiazolil-metil-tio-propiliden-sulfamida.
ES8506666A1 (es) * 1984-09-27 1985-08-01 Bioiberica Procedimiento para la obtencion del n-aminosolfenil-3-(((2-guanidin-4-tiazonil)metil)tio) propionamidina
JPH08155383A (ja) * 1994-12-01 1996-06-18 Kansai Paint Co Ltd 自動車外板塗膜の一時保護方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6056143B2 (ja) * 1979-08-02 1985-12-09 山之内製薬株式会社 アミジン誘導体ならびにその製造法
US4808589A (en) * 1982-02-20 1989-02-28 Smith Kline & French Laboratories Limited Pyrimidone derivatives
US4496737A (en) * 1982-09-27 1985-01-29 Merck & Co., Inc. Process for preparing sulfamylamidine antisecretory agents
ES8504157A1 (es) * 1983-10-07 1985-04-01 Inke Sa Procedimiento para la obtencion de (-1amino-3-(((2-((diaminometileno) amino)-4-tiazolil)metil)tio)propilideno)sulfamida
HU194845B (en) * 1985-09-11 1988-03-28 Richter Gedeon Vegyeszet Process for production of n-sulphamil-3-/2-guanidintiazolil-4-methil-tio/-propion-amidin
HU193608B (en) * 1985-09-11 1987-11-30 Richter Gedeon Vegyeszet Process for production of new dervatives of n-sulphanol-propion-amidine

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES8506665A1 (es) * 1984-05-07 1985-08-01 Inke Sa Procedimiento para la obtencion de la 1-amino-3-2-diamino-metilen-amino-4-tiazolil-metil-tio-propiliden-sulfamida.
ES8506666A1 (es) * 1984-09-27 1985-08-01 Bioiberica Procedimiento para la obtencion del n-aminosolfenil-3-(((2-guanidin-4-tiazonil)metil)tio) propionamidina
ES8506664A1 (es) * 1984-10-17 1985-08-01 Inke Sa Procedimiento para la obtencion de la (1-amino-3(((2-((diamino-metilen) amino)-4-tiazolil)metil)tio)propiliden)sulfamida
JPH08155383A (ja) * 1994-12-01 1996-06-18 Kansai Paint Co Ltd 自動車外板塗膜の一時保護方法

Also Published As

Publication number Publication date
DK434586D0 (da) 1986-09-10
GEP19960471B (en) 1996-05-13
CA1263120A (en) 1989-11-21
AR240319A1 (es) 1990-03-30
NL8602225A (nl) 1987-04-01
KR870003078A (ko) 1987-04-15
NO163010C (no) 1990-03-21
FI863657A0 (fi) 1986-09-10
FI863657A (fi) 1987-03-12
ES2001677A6 (es) 1988-06-01
KR910000237B1 (ko) 1991-01-23
SU1450743A3 (ru) 1989-01-07
SE8603797L (sv) 1987-03-12
PT83348B (pt) 1988-07-29
JPS6296481A (ja) 1987-05-02
DD249479A5 (de) 1987-09-09
HUT42766A (en) 1987-08-28
DK434586A (da) 1987-03-12
GR862308B (en) 1987-01-02
FI86423C (fi) 1992-08-25
DK169920B1 (da) 1995-04-03
NO863616D0 (no) 1986-09-10
GB2180237A (en) 1987-03-25
GB8621742D0 (en) 1986-10-15
CN86105909A (zh) 1987-05-13
SE8603797D0 (sv) 1986-09-10
NO163010B (no) 1989-12-11
AU587279B2 (en) 1989-08-10
HU194845B (en) 1988-03-28
AU6256986A (en) 1987-03-12
JPH0645609B2 (ja) 1994-06-15
PT83348A (pt) 1986-10-01
ATA243486A (de) 1988-03-15
CN1013674B (zh) 1991-08-28
US4835281A (en) 1989-05-30
FI86423B (fi) 1992-05-15
GB2180237B (en) 1989-09-06
NO863616L (no) 1987-03-12
BE905409A (fr) 1986-12-31

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Legal Events

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ELA Expired due to lapse of time