AT385033B - Verfahren zur herstellung von 2,4-diamino-5(3',4',5'-trimethoxy-benzyl)-pyrimidin - Google Patents

Verfahren zur herstellung von 2,4-diamino-5(3',4',5'-trimethoxy-benzyl)-pyrimidin

Info

Publication number
AT385033B
AT385033B AT0244882A AT244882A AT385033B AT 385033 B AT385033 B AT 385033B AT 0244882 A AT0244882 A AT 0244882A AT 244882 A AT244882 A AT 244882A AT 385033 B AT385033 B AT 385033B
Authority
AT
Austria
Prior art keywords
trimethoxy
diamino
pyrimidine
benzyl
producing
Prior art date
Application number
AT0244882A
Other languages
German (de)
English (en)
Other versions
ATA244882A (de
Inventor
Ivan Dr Beck
Imre Biro
Andras Dietz
Elemer Jakfalvi
Laszlo Dr Ladanyi
Istvan Dr Simonyi
Zoltan Chem Ing Takacs
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of ATA244882A publication Critical patent/ATA244882A/de
Application granted granted Critical
Publication of AT385033B publication Critical patent/AT385033B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • C07D239/49—Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Liquid Crystal Substances (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
AT0244882A 1981-06-26 1982-06-24 Verfahren zur herstellung von 2,4-diamino-5(3',4',5'-trimethoxy-benzyl)-pyrimidin AT385033B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU811868A HU186413B (en) 1981-06-26 1981-06-26 Process for producing 2,4-diamino-5-bracket-3-comma above,4-comma above,5-comma above-trimethoxy-benzyl-bracket closed-pyrimidine

Publications (2)

Publication Number Publication Date
ATA244882A ATA244882A (de) 1987-07-15
AT385033B true AT385033B (de) 1988-02-10

Family

ID=10956590

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0244882A AT385033B (de) 1981-06-26 1982-06-24 Verfahren zur herstellung von 2,4-diamino-5(3',4',5'-trimethoxy-benzyl)-pyrimidin

Country Status (22)

Country Link
JP (1) JPS5838265A (cs)
AT (1) AT385033B (cs)
AU (1) AU547822B2 (cs)
BE (1) BE893609A (cs)
CA (1) CA1164458A (cs)
CH (1) CH651828A5 (cs)
CS (1) CS244907B2 (cs)
DD (1) DD202702A5 (cs)
DK (1) DK155668C (cs)
ES (1) ES513481A0 (cs)
FI (1) FI76789C (cs)
FR (1) FR2508449B1 (cs)
GB (1) GB2106098B (cs)
GR (1) GR76158B (cs)
HU (1) HU186413B (cs)
IE (1) IE53347B1 (cs)
IL (1) IL66131A (cs)
IT (1) IT1190888B (cs)
RO (1) RO85316B (cs)
SE (1) SE451134B (cs)
SU (1) SU1147252A3 (cs)
YU (1) YU42264B (cs)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT230379B (de) * 1959-09-03 1963-12-10 Wellcome Found Verfahren zur Herstellung von 2,4-Diamino-5-arylmethylpyrimidinen
DE2635765B2 (de) * 1976-08-09 1978-06-22 Ludwig Heumann & Co Gmbh, 8500 Nuernberg Verfahren zur Herstellung von 2,4-Diamino-5-(3>,4'3'-trimethoxybenzyD-pyrimidin
EP0000334A1 (de) * 1977-07-06 1979-01-24 BASF Aktiengesellschaft 2,4--Diamino-5-benzylpyrimidine, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL122146C (cs) * 1960-09-02
US4115650A (en) * 1976-11-17 1978-09-19 Hoffmann-La Roche Inc. Process for preparing 2,4-diamino-5-(substituted benzyl)-pyrimidines

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT230379B (de) * 1959-09-03 1963-12-10 Wellcome Found Verfahren zur Herstellung von 2,4-Diamino-5-arylmethylpyrimidinen
DE2635765B2 (de) * 1976-08-09 1978-06-22 Ludwig Heumann & Co Gmbh, 8500 Nuernberg Verfahren zur Herstellung von 2,4-Diamino-5-(3>,4'3'-trimethoxybenzyD-pyrimidin
EP0000334A1 (de) * 1977-07-06 1979-01-24 BASF Aktiengesellschaft 2,4--Diamino-5-benzylpyrimidine, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel

Also Published As

Publication number Publication date
AU8534582A (en) 1983-01-06
RO85316B (ro) 1984-10-30
DD202702A5 (de) 1983-09-28
DK155668C (da) 1989-09-18
FI822267L (fi) 1982-12-27
RO85316A (ro) 1984-09-29
DK155668B (da) 1989-05-01
BE893609A (fr) 1982-12-23
GB2106098A (en) 1983-04-07
ES8304948A1 (es) 1983-04-01
FR2508449A1 (fr) 1982-12-31
IT1190888B (it) 1988-02-24
IL66131A0 (en) 1982-09-30
YU42264B (en) 1988-06-30
IE821521L (en) 1982-12-20
GR76158B (cs) 1984-08-03
SE8203913D0 (sv) 1982-06-23
CS244907B2 (en) 1986-08-14
SU1147252A3 (ru) 1985-03-23
GB2106098B (en) 1984-12-19
CS471682A2 (en) 1985-09-17
SE451134B (sv) 1987-09-07
YU138482A (en) 1984-10-31
IE53347B1 (en) 1988-10-26
CA1164458A (en) 1984-03-27
ES513481A0 (es) 1983-04-01
HU186413B (en) 1985-07-29
FI76789C (fi) 1988-12-12
AU547822B2 (en) 1985-11-07
DK275682A (da) 1982-12-27
FI822267A0 (fi) 1982-06-24
IL66131A (en) 1985-03-31
ATA244882A (de) 1987-07-15
IT8222034A0 (it) 1982-06-24
FI76789B (fi) 1988-08-31
FR2508449B1 (fr) 1986-01-10
JPS5838265A (ja) 1983-03-05
CH651828A5 (de) 1985-10-15
SE8203913L (sv) 1982-12-27

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee