IT1190888B - Procedimento per la preparazione della 2,4-diammino-5-(3',4',5',trimetossibenzil)-pirimidina - Google Patents

Procedimento per la preparazione della 2,4-diammino-5-(3',4',5',trimetossibenzil)-pirimidina

Info

Publication number
IT1190888B
IT1190888B IT22034/82A IT2203482A IT1190888B IT 1190888 B IT1190888 B IT 1190888B IT 22034/82 A IT22034/82 A IT 22034/82A IT 2203482 A IT2203482 A IT 2203482A IT 1190888 B IT1190888 B IT 1190888B
Authority
IT
Italy
Prior art keywords
trimetossibenzil
diamino
pyrimidine
procedure
preparation
Prior art date
Application number
IT22034/82A
Other languages
English (en)
Italian (it)
Other versions
IT8222034A0 (it
Inventor
Ivan Beck
Imre Biro
Andras Dietz
Elemer Jakfalvi
Laszlo Ladanyi
Istvan Simonyi
Zoltan Takacs
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of IT8222034A0 publication Critical patent/IT8222034A0/it
Application granted granted Critical
Publication of IT1190888B publication Critical patent/IT1190888B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • C07D239/49—Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Liquid Crystal Substances (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
IT22034/82A 1981-06-26 1982-06-24 Procedimento per la preparazione della 2,4-diammino-5-(3',4',5',trimetossibenzil)-pirimidina IT1190888B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU811868A HU186413B (en) 1981-06-26 1981-06-26 Process for producing 2,4-diamino-5-bracket-3-comma above,4-comma above,5-comma above-trimethoxy-benzyl-bracket closed-pyrimidine

Publications (2)

Publication Number Publication Date
IT8222034A0 IT8222034A0 (it) 1982-06-24
IT1190888B true IT1190888B (it) 1988-02-24

Family

ID=10956590

Family Applications (1)

Application Number Title Priority Date Filing Date
IT22034/82A IT1190888B (it) 1981-06-26 1982-06-24 Procedimento per la preparazione della 2,4-diammino-5-(3',4',5',trimetossibenzil)-pirimidina

Country Status (22)

Country Link
JP (1) JPS5838265A (cs)
AT (1) AT385033B (cs)
AU (1) AU547822B2 (cs)
BE (1) BE893609A (cs)
CA (1) CA1164458A (cs)
CH (1) CH651828A5 (cs)
CS (1) CS244907B2 (cs)
DD (1) DD202702A5 (cs)
DK (1) DK155668C (cs)
ES (1) ES513481A0 (cs)
FI (1) FI76789C (cs)
FR (1) FR2508449B1 (cs)
GB (1) GB2106098B (cs)
GR (1) GR76158B (cs)
HU (1) HU186413B (cs)
IE (1) IE53347B1 (cs)
IL (1) IL66131A (cs)
IT (1) IT1190888B (cs)
RO (1) RO85316B (cs)
SE (1) SE451134B (cs)
SU (1) SU1147252A3 (cs)
YU (1) YU42264B (cs)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1303727B (de) * 1959-09-03 1976-02-05 Ausscheidung aus: 14 45 176 The Wellcome Foundation Ltd., London Alpha-Arylidensubstituierte Propioni-Irile
NL122146C (cs) * 1960-09-02
DE2635765C3 (de) * 1976-08-09 1979-02-08 Ludwig Heumann & Co Gmbh, 8500 Nuernberg Verfahren zur Herstellung von 2,4-EMamino-5-(3',4'r5'-trimethoxybenzyl)-pyrimidin
US4115650A (en) * 1976-11-17 1978-09-19 Hoffmann-La Roche Inc. Process for preparing 2,4-diamino-5-(substituted benzyl)-pyrimidines
DE2730467A1 (de) * 1977-07-06 1979-01-18 Basf Ag Benzylpyrimidine, verfahren zu ihrer herstellung und diese enthaltende arzneimittel

Also Published As

Publication number Publication date
AU8534582A (en) 1983-01-06
RO85316B (ro) 1984-10-30
AT385033B (de) 1988-02-10
DD202702A5 (de) 1983-09-28
DK155668C (da) 1989-09-18
FI822267L (fi) 1982-12-27
RO85316A (ro) 1984-09-29
DK155668B (da) 1989-05-01
BE893609A (fr) 1982-12-23
GB2106098A (en) 1983-04-07
ES8304948A1 (es) 1983-04-01
FR2508449A1 (fr) 1982-12-31
IL66131A0 (en) 1982-09-30
YU42264B (en) 1988-06-30
IE821521L (en) 1982-12-20
GR76158B (cs) 1984-08-03
SE8203913D0 (sv) 1982-06-23
CS244907B2 (en) 1986-08-14
SU1147252A3 (ru) 1985-03-23
GB2106098B (en) 1984-12-19
CS471682A2 (en) 1985-09-17
SE451134B (sv) 1987-09-07
YU138482A (en) 1984-10-31
IE53347B1 (en) 1988-10-26
CA1164458A (en) 1984-03-27
ES513481A0 (es) 1983-04-01
HU186413B (en) 1985-07-29
FI76789C (fi) 1988-12-12
AU547822B2 (en) 1985-11-07
DK275682A (da) 1982-12-27
FI822267A0 (fi) 1982-06-24
IL66131A (en) 1985-03-31
ATA244882A (de) 1987-07-15
IT8222034A0 (it) 1982-06-24
FI76789B (fi) 1988-08-31
FR2508449B1 (fr) 1986-01-10
JPS5838265A (ja) 1983-03-05
CH651828A5 (de) 1985-10-15
SE8203913L (sv) 1982-12-27

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