AT351041B - Verfahren zum herstellen von neuen cyclischen derivaten von 1,4-benzoxazinen und 1,4-benzo- thiazinen sowie von deren salzen und stereo- isomeren - Google Patents

Verfahren zum herstellen von neuen cyclischen derivaten von 1,4-benzoxazinen und 1,4-benzo- thiazinen sowie von deren salzen und stereo- isomeren

Info

Publication number
AT351041B
AT351041B AT985776A AT985776A AT351041B AT 351041 B AT351041 B AT 351041B AT 985776 A AT985776 A AT 985776A AT 985776 A AT985776 A AT 985776A AT 351041 B AT351041 B AT 351041B
Authority
AT
Austria
Prior art keywords
benzoxazines
thiazines
benzo
stereo
isomers
Prior art date
Application number
AT985776A
Other languages
English (en)
Other versions
ATA985776A (de
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Priority to AT331978A priority Critical patent/AT358596B/de
Publication of ATA985776A publication Critical patent/ATA985776A/de
Application granted granted Critical
Publication of AT351041B publication Critical patent/AT351041B/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36Oxygen or sulfur atoms
    • C07D207/402,5-Pyrrolidine-diones
    • C07D207/4042,5-Pyrrolidine-diones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. succinimide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/27Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups
    • C07C205/35Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C205/36Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton to carbon atoms of the same non-condensed six-membered aromatic ring or to carbon atoms of six-membered aromatic rings being part of the same condensed ring system
    • C07C205/37Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton to carbon atoms of the same non-condensed six-membered aromatic ring or to carbon atoms of six-membered aromatic rings being part of the same condensed ring system the oxygen atom of at least one of the etherified hydroxy groups being further bound to an acyclic carbon atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00Sulfones; Sulfoxides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D265/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/281,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/341,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/361,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT985776A 1975-12-30 1976-12-30 Verfahren zum herstellen von neuen cyclischen derivaten von 1,4-benzoxazinen und 1,4-benzo- thiazinen sowie von deren salzen und stereo- isomeren AT351041B (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AT331978A AT358596B (de) 1975-12-30 1978-05-08 Verfahren zum herstellen von neuen cyclischen derivaten von 1,4-benzoxazinen und deren salzen und stereoisomeren

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT30829/75A IT1052009B (it) 1975-12-30 1975-12-30 Imidazo 4.3 c 1.4 benzossazino imidazo 4.3 c 1.4 benzotiazino pirazo 2.1 c 1.4 benzossazino e pirazo 2.1 c 1.4 benzotiazino derivati

Publications (2)

Publication Number Publication Date
ATA985776A ATA985776A (de) 1978-12-15
AT351041B true AT351041B (de) 1979-07-10

Family

ID=11232353

Family Applications (1)

Application Number Title Priority Date Filing Date
AT985776A AT351041B (de) 1975-12-30 1976-12-30 Verfahren zum herstellen von neuen cyclischen derivaten von 1,4-benzoxazinen und 1,4-benzo- thiazinen sowie von deren salzen und stereo- isomeren

Country Status (22)

Country Link
US (1) US4134974A (de)
JP (1) JPS5283397A (de)
AT (1) AT351041B (de)
AU (1) AU504565B2 (de)
BE (1) BE849919A (de)
CA (1) CA1099267A (de)
CH (1) CH630383A5 (de)
CS (1) CS197301B2 (de)
DE (1) DE2658806A1 (de)
DK (1) DK587476A (de)
FI (1) FI61902C (de)
FR (1) FR2336929A1 (de)
GB (1) GB1533020A (de)
HU (1) HU176510B (de)
IL (1) IL51091A (de)
IT (1) IT1052009B (de)
NL (1) NL7614445A (de)
NO (1) NO150882C (de)
NZ (1) NZ182952A (de)
SE (1) SE7613778L (de)
SU (1) SU812181A3 (de)
ZA (1) ZA767588B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4049422A (en) * 1976-03-29 1977-09-20 United States Borax & Chemical Corporation Herbicidal morpholinobenzimidazoles
SE444319B (sv) * 1977-11-18 1986-04-07 Roussel Uclaf Nya imidazobensoxazinderivat, forfarande for framstellning derav och farmaceutiska kompositioner innehallande dessa foreningar
US4254118A (en) * 1979-08-13 1981-03-03 Ayerst, Mckenna & Harrison Inc. 1-Oxo-5H-pyrimido[2,1-c][1,4]benzthiazine-2-carboxylic acid esters
US4254121A (en) * 1979-08-13 1981-03-03 Ayerst, Mckenna & Harrison Inc. 3-Oxo-5H-pyrimido[2,1-c][1,4 ]benzoxazines
US5166343A (en) * 1988-02-05 1992-11-24 Riker Laboratories, Inc. Triazolo[1,5-c]pyrimido[1,4]-azines as bronchodilators
US5089493A (en) * 1988-02-05 1992-02-18 Riker Laboratories, Inc. Triazolo[1,5-C]pyrimido[1,4]azines as bronchodilators
PT625982E (pt) * 1992-02-13 2002-10-31 Upjohn Co 4-oxo- e 4h-imidazo(5,1-c)(1,4)benzoxazinas uteis como agentes de ligacao ao receptor de benzodiazepina
GB9212486D0 (en) * 1992-06-12 1992-07-22 Erba Carlo Spa Derivatives of substituted imidazo benzoxazin-1-one and process for their preparation
US5512566A (en) * 1993-10-25 1996-04-30 Ortho Pharmaceutical Corporation Tricyclic compounds having affinity for the 5-HT1A receptor
GB9410469D0 (en) * 1994-05-25 1994-07-13 Erba Farmitalia Imidazolylalkyl derivatives of imidazo (5,1-c) (1,4) benzoxazin-1-one and process for their preparation
AU4547796A (en) * 1995-02-03 1996-08-21 Sankyo Company Limited Hexahydropyrazinoquinoline derivatives
WO2007087250A2 (en) * 2006-01-23 2007-08-02 Amira Pharmaceuticals, Inc. Tricyclic inhibitors of 5-lipoxygenase
WO2014089904A1 (en) 2012-12-10 2014-06-19 Abbvie Inc. Triazinone compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3929783A (en) * 1974-12-06 1975-12-30 Squibb & Sons Inc 1-Substituted-4-phenyl-4H-{8 1,2,4{9 triazolo{8 3,4-C{9 {8 1,4{9 {0 benzothiazines or benzoxazines
US4035495A (en) * 1975-02-10 1977-07-12 Ayerst Mckenna And Harrison Ltd. Pyrrolobenzoxazines, pyrrolobenzothiazines and process therefor

Also Published As

Publication number Publication date
CS197301B2 (en) 1980-04-30
FR2336929A1 (fr) 1977-07-29
FI61902B (fi) 1982-06-30
AU2086376A (en) 1978-06-29
US4134974A (en) 1979-01-16
NL7614445A (nl) 1977-07-04
BE849919A (fr) 1977-04-15
ATA985776A (de) 1978-12-15
FR2336929B1 (de) 1980-04-18
CH630383A5 (de) 1982-06-15
DK587476A (da) 1977-07-01
JPS5283397A (en) 1977-07-12
IT1052009B (it) 1981-06-20
CA1099267A (en) 1981-04-14
DE2658806A1 (de) 1977-07-14
IL51091A (en) 1984-01-31
NO150882C (no) 1985-01-09
HU176510B (en) 1981-03-28
NO764395L (de) 1977-07-01
GB1533020A (en) 1978-11-22
SE7613778L (sv) 1977-07-01
SU812181A3 (ru) 1981-03-07
FI763752A (de) 1977-07-01
NZ182952A (en) 1980-05-08
ZA767588B (en) 1977-11-30
IL51091A0 (en) 1977-02-28
FI61902C (fi) 1982-10-11
NO150882B (no) 1984-09-24
AU504565B2 (en) 1979-10-18

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties