AT375358B - Verfahren zum herstellen von neuen piperazinmethaniminderivaten und von deren saeureadditionssalzen - Google Patents

Verfahren zum herstellen von neuen piperazinmethaniminderivaten und von deren saeureadditionssalzen

Info

Publication number
AT375358B
AT375358B AT0291379A AT291379A AT375358B AT 375358 B AT375358 B AT 375358B AT 0291379 A AT0291379 A AT 0291379A AT 291379 A AT291379 A AT 291379A AT 375358 B AT375358 B AT 375358B
Authority
AT
Austria
Prior art keywords
methanine
derivatives
acid addition
addition salts
producing new
Prior art date
Application number
AT0291379A
Other languages
English (en)
Other versions
ATA291379A (de
Original Assignee
Laroche Navarron Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laroche Navarron Sa filed Critical Laroche Navarron Sa
Publication of ATA291379A publication Critical patent/ATA291379A/de
Application granted granted Critical
Publication of AT375358B publication Critical patent/AT375358B/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • C07D295/03Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00Ethers; Compounds having groups, groups or groups
    • C07C43/02Ethers
    • C07C43/20Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/225Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/195Radicals derived from nitrogen analogues of carboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT0291379A 1978-04-27 1979-04-18 Verfahren zum herstellen von neuen piperazinmethaniminderivaten und von deren saeureadditionssalzen AT375358B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1674478 1978-04-27

Publications (2)

Publication Number Publication Date
ATA291379A ATA291379A (de) 1983-12-15
AT375358B true AT375358B (de) 1984-07-25

Family

ID=10082882

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0291379A AT375358B (de) 1978-04-27 1979-04-18 Verfahren zum herstellen von neuen piperazinmethaniminderivaten und von deren saeureadditionssalzen

Country Status (16)

Country Link
US (1) US4259334A (de)
EP (1) EP0005385B1 (de)
JP (1) JPS55370A (de)
AT (1) AT375358B (de)
AU (1) AU521238B2 (de)
CA (1) CA1127156A (de)
CS (1) CS226185B2 (de)
DE (1) DE2963600D1 (de)
ES (2) ES8100282A1 (de)
FI (1) FI69841C (de)
HU (1) HU178272B (de)
IE (1) IE47950B1 (de)
NZ (1) NZ190293A (de)
OA (1) OA06247A (de)
PH (1) PH15270A (de)
ZA (1) ZA791944B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4400381A (en) * 1981-07-31 1983-08-23 Laroche-Navarron, S.A. Piperazine derivatives of theophylline
US4374837A (en) * 1981-07-31 1983-02-22 Laroche Navarron, S.A. Piperazine derivatives of theobromine
US4515947A (en) * 1982-08-11 1985-05-07 Eastman Kodak Company Cyanoalkylpiperazines and methods for their preparation and use
US4713382A (en) * 1985-05-30 1987-12-15 Syntex (U.S.A.) Inc. N-phenyl-4-phenyl-1-piperazinecarboxamidines and related compounds as antiarrhythmic agents
EP1216988A4 (de) 1999-09-28 2005-04-20 Nihon Nohyaku Co Ltd Thioalkylamin-derivate und verfahren zu ihrer herstellung

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1810836A1 (de) * 1967-12-28 1970-01-08 Chinoin Gyogyszer Es Vegyeszet Neue Benzamidinderivate und Verfahren zur Herstellung derselben
US4115569A (en) * 1971-11-19 1978-09-19 Hoechst Aktiengesellschaft Cyclic diamine derivatives
SE397088B (sv) * 1972-06-17 1977-10-17 Sumitomo Chemical Co Forfarande for framstellning av nya 2-propanolderivat
US3793322A (en) * 1972-12-15 1974-02-19 Usv Pharma Corp 1,4-disubstituted piperazines

Also Published As

Publication number Publication date
ES8103740A1 (es) 1981-03-16
CA1127156A (en) 1982-07-06
DE2963600D1 (en) 1982-10-28
IE790872L (en) 1978-10-27
ZA791944B (en) 1980-04-30
US4259334A (en) 1981-03-31
ES488835A0 (es) 1981-03-16
EP0005385B1 (de) 1982-09-01
JPS55370A (en) 1980-01-05
ATA291379A (de) 1983-12-15
PH15270A (en) 1982-11-02
FI69841B (fi) 1985-12-31
EP0005385A1 (de) 1979-11-14
HU178272B (en) 1982-04-28
OA06247A (fr) 1981-06-30
FI69841C (fi) 1986-05-26
CS226185B2 (en) 1984-03-19
ES480637A0 (es) 1980-11-01
AU521238B2 (en) 1982-03-25
IE47950B1 (en) 1984-07-25
FI791350A (fi) 1979-10-28
NZ190293A (en) 1980-11-28
AU4633179A (en) 1979-11-01
ES8100282A1 (es) 1980-11-01

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee