FI69841C - Foerfarande foer framstaellning av terapeutiskt anvaendbara 1-fenoxi- eller fenyltio- eller fenylalkyl)-4-bensimidoylpi peaziner - Google Patents

Foerfarande foer framstaellning av terapeutiskt anvaendbara 1-fenoxi- eller fenyltio- eller fenylalkyl)-4-bensimidoylpi peaziner Download PDF

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Publication number
FI69841C
FI69841C FI791350A FI791350A FI69841C FI 69841 C FI69841 C FI 69841C FI 791350 A FI791350 A FI 791350A FI 791350 A FI791350 A FI 791350A FI 69841 C FI69841 C FI 69841C
Authority
FI
Finland
Prior art keywords
ppm
group
formula
alkyl group
piperazine
Prior art date
Application number
FI791350A
Other languages
English (en)
Finnish (fi)
Other versions
FI791350A (fi
FI69841B (fi
Inventor
Jean-Claude Pascal
Henri Pinhas
Original Assignee
Laroche Navarron Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laroche Navarron Sa filed Critical Laroche Navarron Sa
Publication of FI791350A publication Critical patent/FI791350A/fi
Application granted granted Critical
Publication of FI69841B publication Critical patent/FI69841B/fi
Publication of FI69841C publication Critical patent/FI69841C/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/225—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/195—Radicals derived from nitrogen analogues of carboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI791350A 1978-04-27 1979-04-25 Foerfarande foer framstaellning av terapeutiskt anvaendbara 1-fenoxi- eller fenyltio- eller fenylalkyl)-4-bensimidoylpi peaziner FI69841C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB1674478 1978-04-27
GB1674478 1978-04-27

Publications (3)

Publication Number Publication Date
FI791350A FI791350A (fi) 1979-10-28
FI69841B FI69841B (fi) 1985-12-31
FI69841C true FI69841C (fi) 1986-05-26

Family

ID=10082882

Family Applications (1)

Application Number Title Priority Date Filing Date
FI791350A FI69841C (fi) 1978-04-27 1979-04-25 Foerfarande foer framstaellning av terapeutiskt anvaendbara 1-fenoxi- eller fenyltio- eller fenylalkyl)-4-bensimidoylpi peaziner

Country Status (16)

Country Link
US (1) US4259334A (de)
EP (1) EP0005385B1 (de)
JP (1) JPS55370A (de)
AT (1) AT375358B (de)
AU (1) AU521238B2 (de)
CA (1) CA1127156A (de)
CS (1) CS226185B2 (de)
DE (1) DE2963600D1 (de)
ES (2) ES8100282A1 (de)
FI (1) FI69841C (de)
HU (1) HU178272B (de)
IE (1) IE47950B1 (de)
NZ (1) NZ190293A (de)
OA (1) OA06247A (de)
PH (1) PH15270A (de)
ZA (1) ZA791944B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4374837A (en) * 1981-07-31 1983-02-22 Laroche Navarron, S.A. Piperazine derivatives of theobromine
US4400381A (en) * 1981-07-31 1983-08-23 Laroche-Navarron, S.A. Piperazine derivatives of theophylline
US4515947A (en) * 1982-08-11 1985-05-07 Eastman Kodak Company Cyanoalkylpiperazines and methods for their preparation and use
US4713382A (en) * 1985-05-30 1987-12-15 Syntex (U.S.A.) Inc. N-phenyl-4-phenyl-1-piperazinecarboxamidines and related compounds as antiarrhythmic agents
US6639109B1 (en) 1999-09-28 2003-10-28 Nihon Nohyaku Co., Ltd. Process for production of thioalkylamine derivatives

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1810836A1 (de) * 1967-12-28 1970-01-08 Chinoin Gyogyszer Es Vegyeszet Neue Benzamidinderivate und Verfahren zur Herstellung derselben
US4115569A (en) * 1971-11-19 1978-09-19 Hoechst Aktiengesellschaft Cyclic diamine derivatives
CA1012540A (en) * 1972-06-17 1977-06-21 Sumitomo Chemical Company 2-propanol derivatives and preparation thereof
US3793322A (en) * 1972-12-15 1974-02-19 Usv Pharma Corp 1,4-disubstituted piperazines

Also Published As

Publication number Publication date
CA1127156A (en) 1982-07-06
AU521238B2 (en) 1982-03-25
ES480637A0 (es) 1980-11-01
ES8103740A1 (es) 1981-03-16
IE47950B1 (en) 1984-07-25
AU4633179A (en) 1979-11-01
ES8100282A1 (es) 1980-11-01
NZ190293A (en) 1980-11-28
IE790872L (en) 1978-10-27
HU178272B (en) 1982-04-28
FI791350A (fi) 1979-10-28
EP0005385A1 (de) 1979-11-14
DE2963600D1 (en) 1982-10-28
OA06247A (fr) 1981-06-30
US4259334A (en) 1981-03-31
CS226185B2 (en) 1984-03-19
JPS55370A (en) 1980-01-05
ES488835A0 (es) 1981-03-16
FI69841B (fi) 1985-12-31
AT375358B (de) 1984-07-25
EP0005385B1 (de) 1982-09-01
ATA291379A (de) 1983-12-15
ZA791944B (en) 1980-04-30
PH15270A (en) 1982-11-02

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Legal Events

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MM Patent lapsed

Owner name: LAROCHE NAVARRON S.A.