AT339281B - Verfahren zur herstellung von neuen 1-aryloxy-2-hydroxy-4-sek.aminobutanen und deren nichttoxischen saureadditionssalzen - Google Patents

Verfahren zur herstellung von neuen 1-aryloxy-2-hydroxy-4-sek.aminobutanen und deren nichttoxischen saureadditionssalzen

Info

Publication number
AT339281B
AT339281B AT114075A AT114075A AT339281B AT 339281 B AT339281 B AT 339281B AT 114075 A AT114075 A AT 114075A AT 114075 A AT114075 A AT 114075A AT 339281 B AT339281 B AT 339281B
Authority
AT
Austria
Prior art keywords
aminobutanes
aryloxy
sec
hydroxy
preparation
Prior art date
Application number
AT114075A
Other languages
German (de)
English (en)
Other versions
ATA114075A (de
Inventor
Kalman Dr Chem Ing Harsanyi
Dezso Dr Chem Ing Korbonits
Erzsebet Dr Molnar
Jozsef Dr Szegi
Original Assignee
Chinoin Gyogyszer Es Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet
Priority to AT729676A priority Critical patent/AT340899B/de
Publication of ATA114075A publication Critical patent/ATA114075A/de
Application granted granted Critical
Publication of AT339281B publication Critical patent/AT339281B/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/28Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines
    • C07C217/30Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring
    • C07C217/32Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
    • C07C217/34Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted by halogen atoms, by trihalomethyl, nitro or nitroso groups, or by singly-bound oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/28Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines
    • C07C217/30Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/52Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups or amino groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated
AT114075A 1974-02-20 1975-02-17 Verfahren zur herstellung von neuen 1-aryloxy-2-hydroxy-4-sek.aminobutanen und deren nichttoxischen saureadditionssalzen AT339281B (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AT729676A AT340899B (de) 1974-02-20 1976-10-01 Verfahren zur herstellung von neuen 1-aryloxy-2-hydroxy-4-sek.aminobutanen und deren nichttoxischen saureadditionssalzen

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HUCI1449A HU169464B (ja) 1974-02-20 1974-02-20

Publications (2)

Publication Number Publication Date
ATA114075A ATA114075A (de) 1977-02-15
AT339281B true AT339281B (de) 1977-10-10

Family

ID=10994508

Family Applications (1)

Application Number Title Priority Date Filing Date
AT114075A AT339281B (de) 1974-02-20 1975-02-17 Verfahren zur herstellung von neuen 1-aryloxy-2-hydroxy-4-sek.aminobutanen und deren nichttoxischen saureadditionssalzen

Country Status (22)

Country Link
JP (1) JPS5929063B2 (ja)
AT (1) AT339281B (ja)
BE (1) BE825745A (ja)
BG (2) BG26367A4 (ja)
CA (1) CA1074338A (ja)
CH (1) CH619684A5 (ja)
CS (1) CS199578B2 (ja)
DD (1) DD119414A5 (ja)
DE (1) DE2506355C2 (ja)
DK (1) DK141935B (ja)
ES (2) ES434784A1 (ja)
FI (1) FI61304C (ja)
FR (1) FR2261001B1 (ja)
GB (1) GB1457086A (ja)
HU (1) HU169464B (ja)
IL (1) IL46634A (ja)
NL (1) NL182698C (ja)
NO (1) NO141754C (ja)
PL (2) PL99025B1 (ja)
SE (1) SE433935B (ja)
SU (1) SU1025327A3 (ja)
YU (2) YU36916B (ja)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL48309A (en) * 1974-10-25 1980-01-31 Robins Co Inc A H 1-aryloxy-4-amino-2-butanols and pharmaceutical compositions containing them
EP0097000B1 (en) * 1982-06-10 1987-09-09 Beecham Wuelfing GmbH & Co KG Amine derivatives

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1245148A (en) * 1968-11-18 1971-09-08 Pfizer Ltd Propanolamine derivatives
DE1957706C3 (de) * 1968-11-18 1978-06-29 Pfizer Corp., Colon (Panama) Kernsubstituierte 3-Phenoxy-l-phenoxyalkylamino-propan-2-ole und Arzneimittel auf deren Basis
SE384853B (sv) * 1972-04-04 1976-05-24 Haessle Ab Forfarande for framstellning av nya aminer
AT305245B (de) * 1969-09-24 1973-02-12 Ici Ltd Verfahren zur Herstellung von neuen substituierten 1-Phenoxy-2-hydroxy-3-alkylaminopropanen und von deren Säureadditionssalzen

Also Published As

Publication number Publication date
CS199578B2 (en) 1980-07-31
GB1457086A (en) 1976-12-01
DK141935C (ja) 1980-12-08
ES453326A1 (es) 1977-11-16
DE2506355A1 (de) 1975-08-21
IL46634A (en) 1979-01-31
BG26366A3 (ja) 1979-03-15
NL182698C (nl) 1988-05-02
YU37116B (en) 1984-08-31
DE2506355C2 (de) 1983-10-06
SE7501801L (ja) 1975-08-21
FI61304B (fi) 1982-03-31
NO750566L (ja) 1975-08-21
FI750443A (ja) 1975-08-21
NL7501951A (nl) 1975-08-22
FR2261001B1 (ja) 1978-07-21
FR2261001A1 (ja) 1975-09-12
JPS50117728A (ja) 1975-09-16
IL46634A0 (en) 1975-04-25
YU167681A (en) 1983-04-27
ATA114075A (de) 1977-02-15
DD119414A5 (ja) 1976-04-20
BE825745A (fr) 1975-06-16
BG26367A4 (ja) 1979-03-15
SE433935B (sv) 1984-06-25
JPS5929063B2 (ja) 1984-07-18
DK60875A (ja) 1975-10-20
FI61304C (fi) 1982-07-12
PL99025B1 (pl) 1978-06-30
CH619684A5 (en) 1980-10-15
YU37375A (en) 1982-06-18
HU169464B (ja) 1976-11-28
CA1074338A (en) 1980-03-25
ES434784A1 (es) 1977-03-16
NO141754B (no) 1980-01-28
YU36916B (en) 1984-08-31
SU1025327A3 (ru) 1983-06-23
PL99023B1 (pl) 1978-06-30
DK141935B (da) 1980-07-21
NO141754C (no) 1980-05-07

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Legal Events

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ELJ Ceased due to non-payment of the annual fee
REN Ceased due to non-payment of the annual fee