AT337362B - Verfahren zur herstellung von 7beta-amino-3-cephem-3(bzw.-2)-o1-4-carbonsaureverbindungen und deren derivaten - Google Patents

Verfahren zur herstellung von 7beta-amino-3-cephem-3(bzw.-2)-o1-4-carbonsaureverbindungen und deren derivaten

Info

Publication number
AT337362B
AT337362B AT108275A AT108275A AT337362B AT 337362 B AT337362 B AT 337362B AT 108275 A AT108275 A AT 108275A AT 108275 A AT108275 A AT 108275A AT 337362 B AT337362 B AT 337362B
Authority
AT
Austria
Prior art keywords
7beta
cephem
derivatives
amino
production
Prior art date
Application number
AT108275A
Other languages
German (de)
English (en)
Other versions
ATA108275A (de
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH269374A external-priority patent/CH601310A5/de
Priority claimed from CH776674A external-priority patent/CH610584A5/de
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Priority to AT488776A priority Critical patent/AT350581B/de
Priority to AT488876A priority patent/AT350066B/de
Priority to AT488676A priority patent/AT350065B/de
Publication of ATA108275A publication Critical patent/ATA108275A/de
Application granted granted Critical
Publication of AT337362B publication Critical patent/AT337362B/de
Priority to AT28178A priority patent/AT350068B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C313/00—Sulfinic acids; Sulfenic acids; Halides, esters or anhydrides thereof; Amides of sulfinic or sulfenic acids, i.e. compounds having singly-bound oxygen atoms of sulfinic or sulfenic groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C313/02—Sulfinic acids; Derivatives thereof
    • C07C313/04—Sulfinic acids; Esters thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
    • C07D205/095—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4 and with a nitrogen atom directly attached in position 3
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT108275A 1974-02-26 1975-02-13 Verfahren zur herstellung von 7beta-amino-3-cephem-3(bzw.-2)-o1-4-carbonsaureverbindungen und deren derivaten AT337362B (de)

Priority Applications (4)

Application Number Priority Date Filing Date Title
AT488776A AT350581B (de) 1974-02-26 1975-02-13 Verfahren zur herstellung von 3-methylenbutter- saeureazetidinderivaten und deren salzen
AT488876A AT350066B (de) 1974-02-26 1975-02-13 Verfahren zur herstellung von neuen 3-hydroxycrotonsaeureazetidinderivaten und deren salzen
AT488676A AT350065B (de) 1974-02-26 1975-02-13 Verfahren zur herstellung von neuen veraetherten 3-hydroxycrotonsaeureazetidin- derivaten und deren salzen
AT28178A AT350068B (de) 1974-02-26 1978-01-16 Verfahren zur herstellung von neuen 3-methylenbuttersaeureazetidinderivaten und deren salzen

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH269374A CH601310A5 (en) 1974-02-26 1974-02-26 7-Amino-3-hydroxy-2(or 3)-cephem-4-carboxylic acid derivs prepn
CH776674A CH610584A5 (en) 1974-02-26 1974-06-05 Process for the preparation of 2-(3-amino-2-oxo-4-sulphonylthio-1- azetidinyl)-3-methylenebutyric acid derivatives
CH1100074 1974-08-12

Publications (2)

Publication Number Publication Date
ATA108275A ATA108275A (de) 1976-10-15
AT337362B true AT337362B (de) 1977-06-27

Family

ID=27173851

Family Applications (2)

Application Number Title Priority Date Filing Date
AT108275A AT337362B (de) 1974-02-26 1975-02-13 Verfahren zur herstellung von 7beta-amino-3-cephem-3(bzw.-2)-o1-4-carbonsaureverbindungen und deren derivaten
AT28178A AT350068B (de) 1974-02-26 1978-01-16 Verfahren zur herstellung von neuen 3-methylenbuttersaeureazetidinderivaten und deren salzen

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT28178A AT350068B (de) 1974-02-26 1978-01-16 Verfahren zur herstellung von neuen 3-methylenbuttersaeureazetidinderivaten und deren salzen

Country Status (21)

Country Link
JP (1) JPS625919B2 (fr)
AR (1) AR208538A1 (fr)
AT (2) AT337362B (fr)
AU (1) AU498131B2 (fr)
BE (1) BE825919A (fr)
BG (1) BG26201A3 (fr)
CA (2) CA1059988A (fr)
DD (1) DD117074A5 (fr)
DE (1) DE2506330A1 (fr)
DK (2) DK73475A (fr)
ES (2) ES435110A1 (fr)
FI (1) FI66389C (fr)
FR (1) FR2261761B1 (fr)
GB (1) GB1503581A (fr)
HU (1) HU175212B (fr)
IE (1) IE40695B1 (fr)
IL (1) IL46699A (fr)
NL (1) NL7502292A (fr)
NO (1) NO750625L (fr)
NZ (1) NZ176623A (fr)
SE (3) SE431652B (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1044247B (it) * 1974-08-02 1980-03-20 Farmaceutici Italia Intermedi per la sintesi di derivati b lattamici e procedimento per la loro preparazone
JPS5198265A (fr) * 1975-02-17 1976-08-30
CA1136132A (fr) * 1975-02-17 1982-11-23 Teruji Tsuji Cyclisation pour fermer des noyaux cephem et intermediaires ainsi obtenus
AT342197B (de) * 1975-02-20 1978-03-28 Ciba Geigy Ag Neues verfahren zur herstellung von 3-cephemverbindungen
US4029645A (en) * 1975-11-17 1977-06-14 E. R. Squibb & Sons, Inc. Mercury intermediates useful in the preparation of 2-alkoxy cephalosporins
JPH0639474B2 (ja) * 1983-03-04 1994-05-25 大塚化学株式会社 セファロスポリン化合物の製造法
JPS59228854A (ja) * 1983-06-08 1984-12-22 真井　康博 薬液収納兼即効注出器
JPS60237061A (ja) * 1984-05-08 1985-11-25 Otsuka Chem Co Ltd アゼチジノン誘導体の製造法
GB2152497B (en) * 1983-11-28 1987-08-05 Otsuka Kagaku Kk Process for the preparation of azetidinone derivatives
JPS60115562A (ja) * 1983-11-28 1985-06-22 Otsuka Chem Co Ltd アゼチジノン誘導体の製造法
JPS60126263A (ja) * 1983-12-12 1985-07-05 Otsuka Chem Co Ltd アゼチジノン誘導体の製造法
JPS61178961A (ja) * 1985-02-01 1986-08-11 Otsuka Chem Co Ltd アゼチジノン誘導体の製造法
DE3725375A1 (de) * 1987-07-31 1989-02-09 Bayer Ag Stabile oxapenem-3-carbonsaeuren
JP3195959B2 (ja) * 1991-03-13 2001-08-06 大塚化学株式会社 ３−ヒドロキシセフェム誘導体の製造法
WO2004039813A1 (fr) * 2002-11-01 2004-05-13 Orchid Chemicals & Pharmaceuticals Ltd Procede ameliore de preparation de derives de chloromethylcepheme
EA024847B1 (ru) 2011-12-20 2016-10-31 Рибосайенс Ллк 4'-азидо,3'-фторзамещенные производные нуклеозидов в качестве ингибиторов репликации рнк вируса гепатита с
CN104011061B (zh) 2011-12-20 2017-06-13 里博科学有限责任公司 作为hcv rna复制抑制剂的2‘,4’‑二氟‑2‘‑甲基取代的核苷衍生物
US20180200280A1 (en) 2013-05-16 2018-07-19 Riboscience Llc 4'-Fluoro-2'-Methyl Substituted Nucleoside Derivatives as Inhibitors of HCV RNA Replication
CN105307661A (zh) 2013-05-16 2016-02-03 里博科学有限责任公司 4’-叠氮基,3’-脱氧基-3’-氟取代的核苷衍生物
UA123533C2 (uk) 2013-05-16 2021-04-21 Рібосаєнс Ллс 4'-фтор-2'-метилзаміщені нуклеозидні похідні
AR112702A1 (es) 2017-09-21 2019-11-27 Riboscience Llc Derivados de nucleósidos sustituidos con 4’-fluoro-2’-metilo como inhibidores de la replicación de hcv arn

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2230372A1 (de) * 1972-06-21 1973-01-11 Fujisawa Pharmaceutical Co Verfahren zur herstellung von oxidierten penam-derivaten
SE428022B (sv) * 1972-06-29 1983-05-30 Ciba Geigy Ag 7beta-amino-cefam-3-on-4-karboxylsyraforeningar till anvendning for framstellning av cefalosporinderivat
AR206201A1 (es) * 1972-06-29 1976-07-07 Ciba Geigy Ag Procedimiento para la obtencion de compuestos de acido 7beta-amino-3-cefem-3-01-4-carboxilico0-substituidos

Also Published As

Publication number Publication date
SE7807811L (sv) 1978-07-13
NZ176623A (en) 1978-04-03
SE7807810L (sv) 1978-07-13
JPS50129590A (fr) 1975-10-13
CA1080713A (fr) 1980-07-01
FR2261761B1 (fr) 1978-08-18
BE825919A (fr) 1975-08-25
ES452915A1 (es) 1977-11-01
SE7501317L (fr) 1975-08-27
NL7502292A (nl) 1975-08-28
IL46699A0 (en) 1975-04-25
IL46699A (en) 1977-11-30
DD117074A5 (fr) 1975-12-20
JPS625919B2 (fr) 1987-02-07
SE438854B (sv) 1985-05-13
AU498131B2 (en) 1979-02-15
SE431652B (sv) 1984-02-20
IE40695B1 (en) 1979-08-01
BG26201A3 (bg) 1979-02-15
ATA28178A (de) 1978-10-15
IE40695L (en) 1975-08-26
FI66389B (fi) 1984-06-29
DE2506330A1 (de) 1975-09-04
DK73475A (fr) 1975-10-20
GB1503581A (en) 1978-03-15
AR208538A1 (es) 1977-02-15
FI750503A (fr) 1975-08-27
ES435110A1 (es) 1977-03-16
HU175212B (hu) 1980-06-28
SE438855B (sv) 1985-05-13
ATA108275A (de) 1976-10-15
FI66389C (fi) 1984-10-10
CA1059988A (fr) 1979-08-07
DK348678A (da) 1978-08-07
AT350068B (de) 1979-05-10
FR2261761A1 (fr) 1975-09-19
AU7849875A (en) 1976-08-26
NO750625L (fr) 1975-08-27

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee