AR248284A1 - Procedimiento para producir peptidos. - Google Patents

Procedimiento para producir peptidos.

Info

Publication number
AR248284A1
AR248284A1 AR84297748A AR29774884A AR248284A1 AR 248284 A1 AR248284 A1 AR 248284A1 AR 84297748 A AR84297748 A AR 84297748A AR 29774884 A AR29774884 A AR 29774884A AR 248284 A1 AR248284 A1 AR 248284A1
Authority
AR
Argentina
Prior art keywords
protective group
formula
grf analogs
compound
atoxica
Prior art date
Application number
AR84297748A
Other languages
English (en)
Original Assignee
Salk Inst For Biological Studi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/527,292 external-priority patent/US4610976A/en
Priority claimed from US06/541,167 external-priority patent/US4585756A/en
Priority claimed from US06/585,814 external-priority patent/US4605643A/en
Application filed by Salk Inst For Biological Studi filed Critical Salk Inst For Biological Studi
Application granted granted Critical
Publication of AR248284A1 publication Critical patent/AR248284A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/60—Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Fodder In General (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

PROCEDIMIENTO PARA PRODUCIR PEPTIDOS DE FORMULA (I), DONDE R13 ES VAL O ILE; R28 ES SER O ASN; R41 ES ARG O LYS; E Y ES OH O NH2, QUE COMPRENDE: (A) FORMAR UN COMPUESTO DE FORMULA (II) QUE TENGA UN GRUPO PROTECTOR, DONDE (X1), (X2), (X3), (X4), (X5), (X6) Y (X7) SON HIDROGENO O UN GRUPO PROTECTOR Y (X8) ES AMIDA O HIDROXILO O UN GRUPO PROTECTOR, Y (B) SEPARAR EL GRUPO PROTECTOR O GRUPO PROTECTORES DEL COMPUESTO ANTERIOR, (C) CONVERTIR EL PEPTIDO RESULTANTE EN UNA SAL DE ADICION ATOXICA DEL MISMO.
AR84297748A 1983-08-29 1984-08-29 Procedimiento para producir peptidos. AR248284A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US06/527,292 US4610976A (en) 1983-08-29 1983-08-29 Porcine GRF
US06/541,167 US4585756A (en) 1983-10-12 1983-10-12 Bovine GRF
US06/585,814 US4605643A (en) 1984-03-02 1984-03-02 Ovine GRF

Publications (1)

Publication Number Publication Date
AR248284A1 true AR248284A1 (es) 1995-07-12

Family

ID=27414960

Family Applications (1)

Application Number Title Priority Date Filing Date
AR84297748A AR248284A1 (es) 1983-08-29 1984-08-29 Procedimiento para producir peptidos.

Country Status (20)

Country Link
EP (1) EP0137689B1 (es)
JP (1) JPH0676437B2 (es)
KR (1) KR900006560B1 (es)
AR (1) AR248284A1 (es)
AU (1) AU577542B2 (es)
CS (1) CS251085B2 (es)
DD (1) DD228266A5 (es)
DE (1) DE3461641D1 (es)
DK (1) DK161835C (es)
EG (1) EG17263A (es)
ES (1) ES8606401A1 (es)
FI (1) FI81589C (es)
GR (1) GR80227B (es)
HU (1) HU190973B (es)
IE (1) IE57730B1 (es)
IL (1) IL72717A (es)
NO (1) NO167867C (es)
PT (1) PT79094B (es)
SU (1) SU1423000A3 (es)
YU (1) YU45907B (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4518586A (en) * 1983-01-13 1985-05-21 The Salk Institute For Biological Studies GRF Analogs III
IL70530A (en) * 1983-01-13 1986-09-30 Salk Inst For Biological Studi Synthetic peptides having growth hormone releasing factor activity and compositions containing them
DE3436819A1 (de) * 1984-10-06 1986-04-17 Hoechst Ag, 6230 Frankfurt Arzneimittel mit grf-wirkung
DK173350B1 (da) * 1985-02-26 2000-08-07 Sankyo Co Thiazolidinderivater, deres fremstilling og farmaceutisk paæparat indeholdende dem
AU599922B2 (en) * 1985-09-10 1990-08-02 Natinco Nv Improving carcass quality
US4880778A (en) * 1986-05-12 1989-11-14 Eastman Kodak Company Combinations having synergistic growth hormone releasing activity and methods for use thereof
EP0289186A3 (en) * 1987-04-23 1990-04-04 International Minerals And Chemical Corporation Process for increasing the growth rate and enhancing the feed efficiency of meat producing livestock
FR2622455B1 (fr) * 1987-11-04 1991-07-12 Agronomique Inst Nat Rech Application du facteur de stimulation de la secretion de l'hormone de croissance humaine, de ses fragments actifs et des analogues correspondants, pour augmenter la production laitiere et le poids des nouveau-nes chez les mammiferes
JPH01174387A (ja) * 1987-12-28 1989-07-10 Onoda Cement Co Ltd ヤギの成長ホルモン
NZ566267A (en) * 2003-05-01 2009-04-30 Merial Ltd Canine GHRH gene, polypeptides and methods of use
US7468273B2 (en) 2003-05-01 2008-12-23 Meial Limited Canine GHRH gene, polypeptides and methods of use
AU2015346277B2 (en) * 2014-11-12 2020-03-26 Centre Hospitalier Universitaire De Liège Treatment of hormonal disorders of growth
EP3249149B1 (en) * 2015-09-04 2020-02-12 Pica Corp. Extendable device

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ204456A (en) * 1982-06-16 1987-05-29 Salk Inst For Biological Studi Synthetic pancreatic growth-hormone releasing factor
IL70530A (en) * 1983-01-13 1986-09-30 Salk Inst For Biological Studi Synthetic peptides having growth hormone releasing factor activity and compositions containing them
AU575843B2 (en) * 1983-08-10 1988-08-11 The Administrators Of The Tulane Eductional Fund Growth hormone releasing peptides

Also Published As

Publication number Publication date
IL72717A0 (en) 1984-11-30
KR900006560B1 (ko) 1990-09-13
AU577542B2 (en) 1988-09-29
DK161835C (da) 1992-01-20
DK161835B (da) 1991-08-19
DE3461641D1 (en) 1987-01-22
ES535455A0 (es) 1986-04-01
FI843355A0 (fi) 1984-08-24
EG17263A (en) 1991-08-30
FI81589B (fi) 1990-07-31
NO843381L (no) 1985-03-01
HUT35000A (en) 1985-05-28
CS251085B2 (en) 1987-06-11
GR80227B (en) 1985-01-02
AU3244984A (en) 1985-03-07
PT79094A (en) 1984-09-01
EP0137689B1 (en) 1986-12-10
SU1423000A3 (ru) 1988-09-07
JPH0676437B2 (ja) 1994-09-28
EP0137689A1 (en) 1985-04-17
DD228266A5 (de) 1985-10-09
DK413084A (da) 1985-03-01
FI81589C (fi) 1990-11-12
NO167867B (no) 1991-09-09
IE842199L (en) 1985-02-28
YU45907B (sh) 1992-09-07
KR850001536A (ko) 1985-03-30
FI843355A (fi) 1985-03-01
NO167867C (no) 1991-12-18
DK413084D0 (da) 1984-08-29
PT79094B (en) 1986-08-14
YU148884A (en) 1988-04-30
IE57730B1 (en) 1993-03-24
ES8606401A1 (es) 1986-04-01
JPS6072900A (ja) 1985-04-24
IL72717A (en) 1988-01-31
HU190973B (en) 1986-12-28

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