ES8204713A1 - Un procedimiento para aislar un polipeptido purificado - Google Patents

Un procedimiento para aislar un polipeptido purificado

Info

Publication number
ES8204713A1
ES8204713A1 ES504996A ES504996A ES8204713A1 ES 8204713 A1 ES8204713 A1 ES 8204713A1 ES 504996 A ES504996 A ES 504996A ES 504996 A ES504996 A ES 504996A ES 8204713 A1 ES8204713 A1 ES 8204713A1
Authority
ES
Spain
Prior art keywords
asp
pro
preparation
pharmaceutical compositions
compositions containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES504996A
Other languages
English (en)
Other versions
ES504996A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novo Nordisk AS
Original Assignee
Novo Industri AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Industri AS filed Critical Novo Industri AS
Publication of ES504996A0 publication Critical patent/ES504996A0/es
Publication of ES8204713A1 publication Critical patent/ES8204713A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

PROCEDIMIENTO PARA EL AISLAMIENTO DE UN POLIPEPTIDO Y DE SUS SALES FISIOLOGICAMENTE COMPATIBLES, CON UNA PUREZA MINIMA DEL 50 POR 100, QUE TIENE LA SECUENCIA DE AMINOACIDOS ARG SER LEU GLN ASN THR GLU LYS SER ARG SR PHE PRO ALA PRO GLN THR ASP PRO LEU ASP ASP PRO ASP GLN MET THR GLU ASP. CONSISTE EN LA EXTRACCION DEL POLIPEPTIDO A PARTIR DE GLANDULAS PANCREATICAS DE PORCINO CON UNA MEZCLA DE AGUA Y UN DISOLVENTE ORGANICO MISCIBLE EN AGUA QUE TIENE UN PH ENTRE 1,5 Y 4, SEGUIDA DE LA PURIFICACION DEL EXTRACTO POR CROMATOGRAFIA DE INTERCAMBIO ANIONICO Y CATIONICO, ELUCION CON ELUYENTES QUE TIENEN UN PH ENTRE 4 Y 9 Y ENTRE 2 Y 6, RESPECRIVAMENTE, Y FILTRACION A TRAVES DEL GEL. ESTE POLIPEPTIDO TIENE APLICACIONES TERAPEUTICAS POR SU EFECTO INHIBIDOR DE LA SECRECION DE ACIDO GASTRICO.
ES504996A 1980-08-28 1981-08-26 Un procedimiento para aislar un polipeptido purificado Expired ES8204713A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK366380A DK366380A (da) 1980-08-28 1980-08-28 Anvendelsen af grp og salte deraf

Publications (2)

Publication Number Publication Date
ES504996A0 ES504996A0 (es) 1982-05-16
ES8204713A1 true ES8204713A1 (es) 1982-05-16

Family

ID=8125416

Family Applications (1)

Application Number Title Priority Date Filing Date
ES504996A Expired ES8204713A1 (es) 1980-08-28 1981-08-26 Un procedimiento para aislar un polipeptido purificado

Country Status (13)

Country Link
US (1) US4405608A (es)
EP (1) EP0047149B1 (es)
JP (1) JPS5775960A (es)
AT (1) ATE6639T1 (es)
AU (1) AU542310B2 (es)
CA (1) CA1174972A (es)
DE (1) DE3162674D1 (es)
DK (1) DK366380A (es)
ES (1) ES8204713A1 (es)
GR (1) GR74351B (es)
NZ (1) NZ198184A (es)
PT (1) PT73587B (es)
ZA (1) ZA815094B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6019719A (ja) * 1983-07-15 1985-01-31 Asahi Chem Ind Co Ltd 抗腫瘍活性を有する蛋白質
WO2009033819A2 (en) * 2007-09-11 2009-03-19 Mondobiotech Laboratories Ag Use of a peptide as a therapeutic agent

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US81681A (en) * 1868-09-01 Pcters
US2115418A (en) * 1936-06-03 1938-04-26 Lester R Dragstedt Pancreas-derived product and process of producing it
US3069323A (en) * 1959-09-14 1962-12-18 Armour Pharma Insulin recovery process
US3803305A (en) * 1962-12-28 1974-04-09 Rolland A Lab Process for obtaining extracts from pancreas
US3493399A (en) * 1967-04-11 1970-02-03 Ezra Levin Pancreatic food product
NL6816599A (es) * 1968-11-20 1970-05-22
US3907676A (en) * 1970-07-28 1975-09-23 Novo Terapeutisk Labor As Process for purifying insulin
US3878186A (en) * 1973-05-09 1975-04-15 Lilly Co Eli Process for purifying insulin
DK311477A (da) * 1977-07-08 1979-01-09 Leo Lab Fremgangsmaade ved fremstilling af rent insulin
AU5397579A (en) * 1978-12-26 1980-07-03 Eli Lilly And Company Purifying insulin

Also Published As

Publication number Publication date
EP0047149A1 (en) 1982-03-10
ZA815094B (en) 1982-08-25
JPS5775960A (en) 1982-05-12
US4405608A (en) 1983-09-20
DK366380A (da) 1982-03-01
NZ198184A (en) 1985-08-16
PT73587A (en) 1981-09-01
GR74351B (es) 1984-06-26
EP0047149B1 (en) 1984-03-14
DE3162674D1 (en) 1984-04-19
PT73587B (en) 1982-11-10
AU7470681A (en) 1982-03-04
ATE6639T1 (de) 1984-03-15
ES504996A0 (es) 1982-05-16
CA1174972A (en) 1984-09-25
AU542310B2 (en) 1985-02-14

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