AR246971A1 - Procedimiento para la preparacion de heteroalquilen quinolinaminas fusionadas. - Google Patents
Procedimiento para la preparacion de heteroalquilen quinolinaminas fusionadas.Info
- Publication number
- AR246971A1 AR246971A1 AR88310621A AR31062188A AR246971A1 AR 246971 A1 AR246971 A1 AR 246971A1 AR 88310621 A AR88310621 A AR 88310621A AR 31062188 A AR31062188 A AR 31062188A AR 246971 A1 AR246971 A1 AR 246971A1
- Authority
- AR
- Argentina
- Prior art keywords
- compound
- formula
- hydrogen
- preparation
- quinolinamines
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Hydrogenated Pyridines (AREA)
- Pyrrole Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE UN COMPUESTO DE LA FORMULA (I), DONDE N ES 1-3; R1 ES HIDROGENO, ALQUILO O FENILALQUILO; A ES UN ENLACE DIRECTO O -CH2; X ES HIDROGENO, ALQUILO, HALOGENO O TRIFLUORMETILO; Y ES O O S; UN ESTEREO ISOMERO, ISOMERO OPTICO O GEOMETRICO RESPECTIVO, O UNA SAL DE ADICION DE ACIDO FARMACEUTICAMENTE ACEPTABLE RESPECTIVA, QUE COMPRENDE: A) HACER REACCIONAR UN COMPUESTO DE LA FORMULA (VI), CON TETRAHIDRO-4H-PIRAN-4 ONA O CON TETRAHIDRO-4H-TIOPIRAN-2-3- O 4-ONA PARA PROPORCIONAR UN COMPUESTO DE FORMULA (I), DONDE R1 ES HIDROGENO Y B) OPCIONALMENTE REACCIONAR UN COMPUESTO DE LA FORMULA (I) DONDE R1 ES HIDROGENO, CON FENIL ALCANOILO Y REDUCIR EL COMPUESTO OBTENIDO PARA PROPORCIONAR UN COMPUESTO DE FORMULA (I) DONDE R1 ES FENILALQUILO(C1-C6)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US4156287A | 1987-04-23 | 1987-04-23 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR246971A1 true AR246971A1 (es) | 1994-10-31 |
Family
ID=21917178
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AR88310621A AR246971A1 (es) | 1987-04-23 | 1988-04-21 | Procedimiento para la preparacion de heteroalquilen quinolinaminas fusionadas. |
Country Status (18)
Country | Link |
---|---|
EP (1) | EP0287977B1 (es) |
JP (1) | JP2835050B2 (es) |
KR (1) | KR960006392B1 (es) |
AR (1) | AR246971A1 (es) |
AT (1) | ATE107930T1 (es) |
AU (1) | AU609122B2 (es) |
CA (1) | CA1322368C (es) |
DE (1) | DE3850436T2 (es) |
DK (1) | DK174628B1 (es) |
ES (1) | ES2056849T3 (es) |
FI (1) | FI89801C (es) |
IE (1) | IE64197B1 (es) |
IL (1) | IL86158A (es) |
NO (1) | NO166324C (es) |
NZ (1) | NZ224313A (es) |
PH (1) | PH24884A (es) |
PT (1) | PT87287B (es) |
ZA (1) | ZA882811B (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5202440A (en) * | 1987-10-05 | 1993-04-13 | Pfizer Inc. | Certain 9-amino-2-(or 4)-oxa 1,2,3,4-tetrahydro- or 1,2,3,4,5,6,7,8-octahydro-acridines |
IL87861A0 (en) * | 1987-10-05 | 1989-03-31 | Pfizer | 4-aminopyridine derivatives |
JP2720517B2 (ja) * | 1989-05-31 | 1998-03-04 | 三菱化学株式会社 | 9―アシルアミノーテトラヒドロアクリジン誘導体および該誘導体を有効成分とする記憶障害改善剤 |
ES2042384B1 (es) * | 1991-12-26 | 1994-06-01 | Boehringer Ingelheim Espana | Procedimiento para obtener derivados bis-piridinicos. |
EP1604653A1 (en) | 1998-09-30 | 2005-12-14 | Takeda Pharmaceutical Company Limited | Acetylcholinesterase inhibitors for improving excretory potency of urinary bladder |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3674790A (en) * | 1970-05-01 | 1972-07-04 | American Home Prod | 2,10-disubstituted-1,2,3,4-tetrahydrobenzo(bhq (1,6)naphthyridines useful as cns depressants |
ES431307A1 (es) * | 1973-11-16 | 1976-09-01 | Thomae Gmbh Dr K | Procedimiento para la preparacion de nuevos derivados de quinoleina. |
GB8610980D0 (en) * | 1986-05-06 | 1986-06-11 | Ici America Inc | Heterocyclic fused tricyclic compounds |
JPS63264485A (ja) * | 1986-12-29 | 1988-11-01 | Sumitomo Pharmaceut Co Ltd | アミノキノリン誘導体 |
-
1988
- 1988-04-16 DE DE3850436T patent/DE3850436T2/de not_active Expired - Lifetime
- 1988-04-16 EP EP88106095A patent/EP0287977B1/en not_active Expired - Lifetime
- 1988-04-16 AT AT88106095T patent/ATE107930T1/de not_active IP Right Cessation
- 1988-04-16 ES ES88106095T patent/ES2056849T3/es not_active Expired - Lifetime
- 1988-04-21 PT PT87287A patent/PT87287B/pt not_active IP Right Cessation
- 1988-04-21 PH PH36825A patent/PH24884A/en unknown
- 1988-04-21 ZA ZA882811A patent/ZA882811B/xx unknown
- 1988-04-21 AR AR88310621A patent/AR246971A1/es active
- 1988-04-21 KR KR1019880004516A patent/KR960006392B1/ko not_active IP Right Cessation
- 1988-04-21 FI FI881873A patent/FI89801C/fi not_active IP Right Cessation
- 1988-04-21 NZ NZ224313A patent/NZ224313A/xx unknown
- 1988-04-22 IE IE121488A patent/IE64197B1/en not_active IP Right Cessation
- 1988-04-22 NO NO881775A patent/NO166324C/no unknown
- 1988-04-22 AU AU15099/88A patent/AU609122B2/en not_active Expired
- 1988-04-22 DK DK198802228A patent/DK174628B1/da not_active IP Right Cessation
- 1988-04-22 IL IL8615888A patent/IL86158A/en not_active IP Right Cessation
- 1988-04-22 JP JP63098466A patent/JP2835050B2/ja not_active Expired - Lifetime
- 1988-04-22 CA CA000564915A patent/CA1322368C/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0287977A2 (en) | 1988-10-26 |
NO166324B (no) | 1991-03-25 |
FI89801C (fi) | 1993-11-25 |
IL86158A0 (en) | 1988-11-15 |
EP0287977A3 (en) | 1989-09-06 |
AU1509988A (en) | 1988-10-27 |
NO166324C (no) | 1991-07-03 |
DK222888A (da) | 1988-10-24 |
IE881214L (en) | 1988-10-23 |
EP0287977B1 (en) | 1994-06-29 |
DK222888D0 (da) | 1988-04-22 |
DE3850436T2 (de) | 1994-11-17 |
NO881775D0 (no) | 1988-04-22 |
ATE107930T1 (de) | 1994-07-15 |
NZ224313A (en) | 1991-01-29 |
CA1322368C (en) | 1993-09-21 |
ES2056849T3 (es) | 1994-10-16 |
IE64197B1 (en) | 1995-07-12 |
FI881873A (fi) | 1988-10-24 |
PT87287B (pt) | 1992-08-31 |
DE3850436D1 (de) | 1994-08-04 |
NO881775L (no) | 1988-10-24 |
FI881873A0 (fi) | 1988-04-21 |
KR880012606A (ko) | 1988-11-28 |
KR960006392B1 (ko) | 1996-05-15 |
JPS63284175A (ja) | 1988-11-21 |
DK174628B1 (da) | 2003-07-28 |
PH24884A (en) | 1990-12-26 |
ZA882811B (en) | 1988-10-20 |
FI89801B (fi) | 1993-08-13 |
JP2835050B2 (ja) | 1998-12-14 |
IL86158A (en) | 1994-08-26 |
AU609122B2 (en) | 1991-04-26 |
PT87287A (pt) | 1988-05-01 |
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