AR123779A1 - Método para preparar l-glufosinato - Google Patents
Método para preparar l-glufosinatoInfo
- Publication number
- AR123779A1 AR123779A1 ARP210102829A ARP210102829A AR123779A1 AR 123779 A1 AR123779 A1 AR 123779A1 AR P210102829 A ARP210102829 A AR P210102829A AR P210102829 A ARP210102829 A AR P210102829A AR 123779 A1 AR123779 A1 AR 123779A1
- Authority
- AR
- Argentina
- Prior art keywords
- carbon atoms
- substituted
- unsubstituted
- preparing
- aryl
- Prior art date
Links
- IAJOBQBIJHVGMQ-BYPYZUCNSA-N glufosinate-P Chemical compound CP(O)(=O)CC[C@H](N)C(O)=O IAJOBQBIJHVGMQ-BYPYZUCNSA-N 0.000 title abstract 3
- 125000004432 carbon atom Chemical group C* 0.000 abstract 13
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 125000003118 aryl group Chemical group 0.000 abstract 4
- 125000003342 alkenyl group Chemical group 0.000 abstract 3
- 125000000304 alkynyl group Chemical group 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 3
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 125000001072 heteroaryl group Chemical group 0.000 abstract 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
- C07F9/301—Acyclic saturated acids which can have further substituents on alkyl
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/46—Phosphinous acids [R2POH], [R2P(= O)H]: Thiophosphinous acids including[R2PSH]; [R2P(=S)H]; Aminophosphines [R2PNH2]; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/48—Phosphonous acids [RP(OH)2] including [RHP(=O)(OH)]; Thiophosphonous acids including [RP(SH)2], [RHP(=S)(SH)]; Derivatives thereof
- C07F9/4883—Amides or esteramides thereof, e.g. RP(NR'2)2 or RP(XR')(NR''2) (X = O, S)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/50—Organo-phosphines
- C07F9/5004—Acyclic saturated phosphines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/535—Organo-phosphoranes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
- C07F9/6581—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
- C07F9/6581—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms
- C07F9/6584—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms having one phosphorus atom as ring hetero atom
- C07F9/65842—Cyclic amide derivatives of acids of phosphorus, in which one nitrogen atom belongs to the ring
- C07F9/65844—Cyclic amide derivatives of acids of phosphorus, in which one nitrogen atom belongs to the ring the phosphorus atom being part of a five-membered ring which may be condensed with another ring system
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Catalysts (AREA)
Abstract
Reivindicación 1: Un método para preparar L-glufosinato de fórmula (1), caracterizado porque el método comprende las siguientes etapas: a) preparar un compuesto de fórmula (3) a partir de un compuesto de fórmula (2), y b) preparar L-glufosinato a partir del compuesto de fórmula (3), en donde: X es halógeno; Y es -OR¹ o -N(R²)(R³); R¹, R² y R³ son cada uno independientemente alquilo que tiene 1 - 6 átomos de carbono sustituido o no sustituido, alquenilo que tiene 1 - 6 átomos de carbono sustituido o no sustituido (preferentemente, alquenilo que tiene 2 - 6 átomos de carbono sustituido o no sustituido), alquinilo que tiene 1 - 6 átomos de carbono sustituido o no sustituido (preferentemente, alquinilo que tiene 2 - 6 átomos de carbono sustituido o no sustituido), cicloalquilo que tiene 3 - 10 átomos de carbono sustituido o no sustituido, arilo que tiene 6 - 20 átomos de carbono sustituido o no sustituido, o heteroarilo que tiene 2 - 10 átomos de carbono sustituido o no sustituido, o -Si(R⁴)(R⁵)(R⁶); R⁴, R⁵ y R⁶ son cada uno independientemente alquilo que tiene 1 - 6 átomos de carbono sustituido o no sustituido o arilo que tiene 6 - 20 átomos de carbono sustituido o no sustituido; y los sustituyentes para los grupos alquilo, alquenilo, alquinilo, cicloalquilo, arilo y heteroarilo, son cada uno independientemente halógeno, carboxilo, amino, nitro, ciano, alquilo que tiene 1 - 6 átomos de carbono, arilo que tiene 6 - 10 átomos de carbono, o cicloalquilo que tiene 3 - 10 átomos de carbono.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011093594 | 2020-10-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR123779A1 true AR123779A1 (es) | 2023-01-11 |
Family
ID=81207661
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP210102829A AR123779A1 (es) | 2020-10-14 | 2021-10-13 | Método para preparar l-glufosinato |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US11655265B2 (es) |
| EP (1) | EP4063374B1 (es) |
| JP (1) | JP7404598B2 (es) |
| KR (1) | KR102693943B1 (es) |
| CN (2) | CN114650997B (es) |
| AR (1) | AR123779A1 (es) |
| AU (1) | AU2021360429B2 (es) |
| BR (1) | BR112022012512A2 (es) |
| CA (1) | CA3163462C (es) |
| IL (1) | IL294193B2 (es) |
| MX (1) | MX2022007888A (es) |
| TW (1) | TWI804006B (es) |
| WO (1) | WO2022077989A1 (es) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR126484A1 (es) | 2021-07-20 | 2023-10-11 | Lier Chemical Co Ltd | Método para preparar glufosinato o análogos del mismo |
| CA3240868A1 (en) * | 2021-12-13 | 2023-06-22 | Lei Zhou | L-glufosinate derivative, composition comprising same, preparation method therefor and use thereof |
| CN115636849B (zh) * | 2022-09-09 | 2024-09-20 | 河北威远生物化工有限公司 | 一种l-草铵膦的合成方法 |
| CN116041387B (zh) * | 2022-11-17 | 2023-07-14 | 永农生物科学有限公司 | 一种草铵膦的制备方法 |
| WO2024113549A1 (zh) * | 2022-12-02 | 2024-06-06 | 利尔化学股份有限公司 | 草铵膦或其衍生物的制备方法 |
| TW202423293A (zh) * | 2022-12-02 | 2024-06-16 | 中國大陸商利爾化學股份有限公司 | 草銨膦或其衍生物的製備方法 |
| WO2024146621A1 (zh) * | 2023-01-06 | 2024-07-11 | 利尔化学股份有限公司 | 草铵膦或其衍生物的制备方法 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3846374A (en) * | 1969-02-24 | 1974-11-05 | American Cyanamid Co | 1,2-azaphospholanes and their 2-oxides, 2-sulfides and salts and preparation thereof |
| JP2615791B2 (ja) * | 1988-03-31 | 1997-06-04 | 日産化学工業株式会社 | 有機燐化合物の製造法 |
| CN103396440B (zh) * | 2013-08-23 | 2016-03-16 | 重庆紫光化工股份有限公司 | 一种草铵膦的制备方法 |
| CN105131032A (zh) * | 2015-07-28 | 2015-12-09 | 西安近代化学研究所 | 一种合成l-草铵膦的方法 |
| CN105218579B (zh) * | 2015-09-28 | 2017-11-07 | 江苏七洲绿色化工股份有限公司 | 一种l‑型草铵膦铵盐的合成方法 |
| CN109384811B (zh) * | 2017-08-02 | 2021-06-08 | 四川利尔生物科技有限公司 | 一种l-草铵膦的制备方法 |
| BR112021013271B1 (pt) * | 2019-01-11 | 2024-02-20 | Cj Cheiljedang Corporation | Método de preparação de intermediário de l-glufosinato e de lglufosinato |
| KR102582675B1 (ko) * | 2019-01-11 | 2023-09-25 | 씨제이제일제당 주식회사 | 글루포시네이트 제조 방법 |
| CN111662324B (zh) * | 2019-03-05 | 2023-02-24 | 利尔化学股份有限公司 | 一种制备l-草铵膦的方法 |
| CN111662326B (zh) * | 2019-03-05 | 2023-03-24 | 利尔化学股份有限公司 | 一种制备l-草铵膦的方法 |
| CN111662325B (zh) * | 2019-03-05 | 2023-03-24 | 利尔化学股份有限公司 | 一种制备l-草铵膦的方法 |
| CN109912649A (zh) * | 2019-04-11 | 2019-06-21 | 利尔化学股份有限公司 | L-草铵膦中间体的合成方法 |
| CN110386882A (zh) * | 2019-08-12 | 2019-10-29 | 利尔化学股份有限公司 | (s)-4-氯-2-((乙氧基羰基)氨基)丁酸乙酯的制备方法 |
| CN110845347B (zh) | 2019-11-21 | 2021-10-15 | 利尔化学股份有限公司 | 一种氯代高丝氨酸烷基酯的制备方法 |
-
2021
- 2021-07-20 BR BR112022012512A patent/BR112022012512A2/pt active Search and Examination
- 2021-07-20 CA CA3163462A patent/CA3163462C/en active Active
- 2021-07-20 CN CN202180005915.XA patent/CN114650997B/zh active Active
- 2021-07-20 EP EP21879036.8A patent/EP4063374B1/en active Active
- 2021-07-20 AU AU2021360429A patent/AU2021360429B2/en active Active
- 2021-07-20 JP JP2022544805A patent/JP7404598B2/ja active Active
- 2021-07-20 IL IL294193A patent/IL294193B2/en unknown
- 2021-07-20 WO PCT/CN2021/107238 patent/WO2022077989A1/zh active Application Filing
- 2021-07-20 MX MX2022007888A patent/MX2022007888A/es unknown
- 2021-07-20 KR KR1020227020426A patent/KR102693943B1/ko active IP Right Grant
- 2021-07-20 CN CN202410675691.9A patent/CN118652271A/zh active Pending
- 2021-10-13 AR ARP210102829A patent/AR123779A1/es unknown
- 2021-10-14 TW TW110138220A patent/TWI804006B/zh active
-
2022
- 2022-06-15 US US17/841,410 patent/US11655265B2/en active Active
-
2023
- 2023-04-12 US US18/299,605 patent/US20230399348A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| TW202224561A (zh) | 2022-07-01 |
| EP4063374A4 (en) | 2023-09-27 |
| AU2021360429A1 (en) | 2022-06-23 |
| BR112022012512A2 (pt) | 2023-03-28 |
| KR102693943B1 (ko) | 2024-08-08 |
| KR20220098244A (ko) | 2022-07-11 |
| CA3163462C (en) | 2023-02-28 |
| AU2021360429B2 (en) | 2022-12-01 |
| JP7404598B2 (ja) | 2023-12-26 |
| CN118652271A (zh) | 2024-09-17 |
| CA3163462A1 (en) | 2022-04-21 |
| TWI804006B (zh) | 2023-06-01 |
| IL294193B2 (en) | 2024-02-01 |
| JP2023511204A (ja) | 2023-03-16 |
| US11655265B2 (en) | 2023-05-23 |
| IL294193B1 (en) | 2023-10-01 |
| IL294193A (en) | 2022-08-01 |
| CN114650997B (zh) | 2024-04-26 |
| US20230399348A1 (en) | 2023-12-14 |
| EP4063374A1 (en) | 2022-09-28 |
| CN114650997A (zh) | 2022-06-21 |
| WO2022077989A1 (zh) | 2022-04-21 |
| MX2022007888A (es) | 2022-07-19 |
| EP4063374B1 (en) | 2024-07-17 |
| US20220324888A1 (en) | 2022-10-13 |
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