AR106834A1 - Método de producción de l-metionina - Google Patents

Método de producción de l-metionina

Info

Publication number
AR106834A1
AR106834A1 ARP160103633A ARP160103633A AR106834A1 AR 106834 A1 AR106834 A1 AR 106834A1 AR P160103633 A ARP160103633 A AR P160103633A AR P160103633 A ARP160103633 A AR P160103633A AR 106834 A1 AR106834 A1 AR 106834A1
Authority
AR
Argentina
Prior art keywords
metionine
production method
methionine
production
homoserine
Prior art date
Application number
ARP160103633A
Other languages
English (en)
Inventor
Pedall Joanne
Hampel Michael
HASSELMEYER Marleen
Dr Bathe Brigitte
Dr Fischer Daniel
Dr Ochrombel Ines
Original Assignee
Evonik Degussa Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Evonik Degussa Gmbh filed Critical Evonik Degussa Gmbh
Publication of AR106834A1 publication Critical patent/AR106834A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/12—Methionine; Cysteine; Cystine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1085—Transferases (2.) transferring alkyl or aryl groups other than methyl groups (2.5)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y203/00—Acyltransferases (2.3)
    • C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/01031—Homoserine O-acetyltransferase (2.3.1.31)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y205/00—Transferases transferring alkyl or aryl groups, other than methyl groups (2.5)
    • C12Y205/01—Transferases transferring alkyl or aryl groups, other than methyl groups (2.5) transferring alkyl or aryl groups, other than methyl groups (2.5.1)
    • C12Y205/01049—O-acetylhomoserine aminocarboxypropyltransferase (2.5.1.49)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Método de producción de L-metionina en el cual se cultiva un microorganismo en la presencia de L-homoserina y metil mercaptano, una sal del mismo, o disulfuro de dimetilo, con lo cual se acumula L-metionina en el medio de cultivo.
ARP160103633A 2015-11-27 2016-11-25 Método de producción de l-metionina AR106834A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP15196776 2015-11-27

Publications (1)

Publication Number Publication Date
AR106834A1 true AR106834A1 (es) 2018-02-21

Family

ID=54705525

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP160103633A AR106834A1 (es) 2015-11-27 2016-11-25 Método de producción de l-metionina

Country Status (12)

Country Link
US (1) US11034985B2 (es)
EP (1) EP3380627B1 (es)
KR (1) KR20180086240A (es)
CN (1) CN108291243A (es)
AR (1) AR106834A1 (es)
BR (1) BR112018010747A8 (es)
ES (1) ES2748226T3 (es)
MX (1) MX2018006434A (es)
MY (1) MY186059A (es)
PL (1) PL3380627T3 (es)
RU (1) RU2729012C2 (es)
WO (1) WO2017089077A1 (es)

Family Cites Families (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH525863A (de) 1967-09-12 1972-07-31 Kyowa Hakko Kogyo Kk Verfahren zur Herstellung von L-Homoserin und L-Lysin
WO1993017112A1 (en) 1992-02-20 1993-09-02 Genencor International, Inc. Biosynthesis of methionine using a reduced source of sulfur
US5795776A (en) 1994-03-22 1998-08-18 Bio-Technology General Corp. Expression plasmids regulated by an OSMB promoter
JP4035855B2 (ja) 1996-06-05 2008-01-23 味の素株式会社 Ｌ−リジンの製造法
JP4075087B2 (ja) 1996-12-05 2008-04-16 味の素株式会社 Ｌ−リジンの製造法
RU2144564C1 (ru) 1998-10-13 2000-01-20 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" ФРАГМЕНТ ДНК rhtB, КОДИРУЮЩИЙ СИНТЕЗ БЕЛКА RhtB, ПРИДАЮЩЕГО УСТОЙЧИВОСТЬ К L-ГОМОСЕРИНУ БАКТЕРИЯМ ESCHERICHIA COLI, И СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТ
JP4110641B2 (ja) 1998-11-17 2008-07-02 味の素株式会社 発酵法によるｌ−メチオニンの製造法
JP2000157267A (ja) 1998-11-24 2000-06-13 Ajinomoto Co Inc 変異型ｍｅｔＪ遺伝子及びＬ−メチオニンの製造法
JP4623825B2 (ja) * 1999-12-16 2011-02-02 協和発酵バイオ株式会社 新規ポリヌクレオチド
RU2212447C2 (ru) 2000-04-26 2003-09-20 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" Штамм escherichia coli - продуцент аминокислоты (варианты) и способ получения аминокислот (варианты)
AU2001285844A1 (en) 2000-08-02 2002-02-13 Degussa A.G. Nucleotide sequences which code for the meth gene
DE10109690A1 (de) 2000-09-02 2002-03-14 Degussa Neue für das metY-Gen kodierende Nukleotidsequenzen
US6812016B2 (en) * 2000-09-02 2004-11-02 Degussa Ag Nucleotide sequences which code for the metY gene
EP1345714A1 (en) * 2000-12-22 2003-09-24 Basf Aktiengesellschaft Genes of corynebacterium
DE10303571A1 (de) 2003-01-30 2004-08-12 Degussa Ag Verfahren zur fermentativen Herstellung von L-Aminosäuren unter Verwendung von Stämmen der Familie Enterobacteriaceae
CN101208427A (zh) * 2003-05-30 2008-06-25 米克罗比亚股份有限公司 氨基酸制备的方法和组合物
DE10359594A1 (de) 2003-12-18 2005-07-28 Basf Ag PEF-TU-Expressionseinheiten
FR2864967B1 (fr) 2004-01-12 2006-05-19 Metabolic Explorer Sa Microorganisme evolue pour la production de 1,2-propanediol
WO2005111202A1 (en) 2004-05-12 2005-11-24 Metabolic Explorer Recombinant enzyme with altered feedback sensitivity
KR100651220B1 (ko) 2004-06-29 2006-11-29 씨제이 주식회사 Ｌ-메씨오닌 생산 균주 및 상기 균주를 이용한ｌ-메씨오닌의 생산방법
DE102004035065A1 (de) 2004-07-20 2006-02-16 Basf Ag P-ET-TS-Expressionseinheiten
KR20080036608A (ko) * 2005-07-18 2008-04-28 바스프 에스이 메티오닌 생산 재조합 미생물
ES2355942T3 (es) * 2005-07-18 2011-04-01 Evonik Degussa Gmbh Uso de disulfuro de dimetilo para la producción de metionina en microorganismos.
JP2009501548A (ja) * 2005-07-18 2009-01-22 ビーエーエスエフ ソシエタス・ヨーロピア 微生物におけるメチオニン生産のためのジメチルジスルフィドの使用
US7445879B2 (en) 2005-08-23 2008-11-04 Nukote International, Inc. Preparation of suspension polymerized toners
BRPI0620880B1 (pt) 2006-01-04 2018-10-09 Evonik Degussa Gmbh método para a produção de metionina, pelo cultivo de um microorganismo, e, microorganismo
DE102006004063A1 (de) * 2006-01-28 2007-08-02 Degussa Gmbh Verfahren zur Herstellung von Methionin aus Homoserin
KR100905381B1 (ko) * 2006-07-28 2009-06-30 씨제이제일제당 (주) Ｌ-메치오닌 전구체 생산 균주 및 상기 ｌ-메치오닌전구체로부터의 ｌ-메치오닌 및 유기산의 생산방법
CA2679989C (en) 2007-03-23 2015-07-07 Metabolic Explorer New micro-organisms for the production of 1,2-propanediol obtained by a combination of evolution and rational design
EP2808382B1 (en) 2007-04-11 2016-03-16 CJ CheilJedang Corporation Compositions and methods of producing methionine
WO2009043372A1 (en) 2007-10-02 2009-04-09 Metabolic Explorer Increasing methionine yield
US9005952B2 (en) 2008-04-04 2015-04-14 Cj Cheiljedang Corporation Microorganism producing L-methionine precursor and the method of producing L-methionine precursor using the microorganism
WO2010020290A1 (en) 2008-08-22 2010-02-25 Metabolic Explorer Producing methionine without n-acetyl methionine
KR101048593B1 (ko) * 2009-02-27 2011-07-12 씨제이제일제당 (주) 메칠머캅탄과 디메칠설파이드의 혼합물을 사용하여 메치오닌 생산능을 증가시키는 방법
US8609396B2 (en) 2009-08-28 2013-12-17 Cj Cheiljedang Corporation Microorganism producing O-acetyl-homoserine and the method of producing O-acetyl-homoserine using the microorganism
US8283152B2 (en) 2009-08-28 2012-10-09 Cj Cheiljedang Corporation Microorganism producing O-acetyl-homoserine and the method of producing O-acetyl-homoserine using the microorganism
WO2011073738A1 (en) 2009-12-14 2011-06-23 Metabolic Explorer Use of inducible promoters in the production of methionine
WO2011080301A2 (en) 2009-12-30 2011-07-07 Metabolic Explorer Strains and method for the production of methionine
MX2012007718A (es) 2009-12-30 2012-07-25 Metabolic Explorer Sa Aumento de la produccion de metionina mediante la sobreexpresion de succinato deshidrogenasa.
AR083468A1 (es) 2010-10-25 2013-02-27 Metabolic Explorer Sa Aumento de la disponibilidad de nadph para la produccion de metionina
MY173933A (en) 2010-12-21 2020-02-27 Cj Cheiljedang Corp Modified polypeptide having homoserine acetyltransferase activity and microorganism expressing the same
EP2479279A1 (de) 2011-01-20 2012-07-25 Evonik Degussa GmbH Verfahren zur fermentativen Herstellung schwefelhaltiger Aminosäuren
AR086790A1 (es) 2011-06-29 2014-01-22 Metabolic Explorer Sa Un microorganismo para la produccion de metionina con importacion de glucosa mejorada
US9506093B2 (en) 2012-06-18 2016-11-29 Metabolic Explorer Recombinant microorganism for the fermentative production of methionine
CN105658785B (zh) 2013-08-30 2019-12-06 赢创德固赛有限公司 具有增强的甲硫氨酸流出的用于甲硫氨酸生产的微生物
EP3039153B1 (en) 2013-08-30 2018-08-22 Evonik Degussa GmbH Microorganism for methionine production with improved methionine synthase activity and methionine efflux
SG11201608272RA (en) 2014-04-30 2016-11-29 Evonik Degussa Gmbh Method for producing l-amino acids using an alkaliphilic bacteria
EP2940039A1 (de) 2014-04-30 2015-11-04 Evonik Degussa GmbH Verfahren zur Produktion von L-Aminosäuren in Corynebakterien unter Verwendung eines Glycin spaltenden Systems
CA2959563A1 (en) 2014-09-01 2016-03-10 Metabolic Explorer Method and microorganism for methionine production by fermentation with improved methionine efflux
PL3331998T3 (pl) 2015-08-07 2020-12-28 Evonik Operations Gmbh Wytwarzanie przez fermentację l-metioniny zależne od tiokarboksylanu białka
EP3456833A1 (en) 2017-09-18 2019-03-20 Evonik Degussa GmbH Method for the fermentative production of l-amino acids
EP3498853A1 (en) 2017-12-14 2019-06-19 Evonik Degussa GmbH Method for the fermentative production of l-lysine

Also Published As

Publication number Publication date
MX2018006434A (es) 2018-09-28
CN108291243A (zh) 2018-07-17
BR112018010747A2 (pt) 2018-11-21
ES2748226T3 (es) 2020-03-16
RU2018123145A3 (es) 2020-02-28
US20180346946A1 (en) 2018-12-06
RU2729012C2 (ru) 2020-08-03
MY186059A (en) 2021-06-17
WO2017089077A1 (en) 2017-06-01
EP3380627B1 (en) 2019-08-14
RU2018123145A (ru) 2019-12-30
KR20180086240A (ko) 2018-07-30
US11034985B2 (en) 2021-06-15
PL3380627T3 (pl) 2020-01-31
EP3380627A1 (en) 2018-10-03
BR112018010747A8 (pt) 2019-02-26

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