BR112016027797A2 - métodos e meios de cultura de células compreendendo n-acetilcisteína - Google Patents
métodos e meios de cultura de células compreendendo n-acetilcisteínaInfo
- Publication number
- BR112016027797A2 BR112016027797A2 BR112016027797A BR112016027797A BR112016027797A2 BR 112016027797 A2 BR112016027797 A2 BR 112016027797A2 BR 112016027797 A BR112016027797 A BR 112016027797A BR 112016027797 A BR112016027797 A BR 112016027797A BR 112016027797 A2 BR112016027797 A2 BR 112016027797A2
- Authority
- BR
- Brazil
- Prior art keywords
- cell
- cell culture
- acetylcysteine
- culture methods
- media
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0018—Culture media for cell or tissue culture
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
- C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/32—Amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/34—Sugars
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/36—Lipids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/44—Thiols, e.g. mercaptoethanol
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/999—Small molecules not provided for elsewhere
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2511/00—Cells for large scale production
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Abstract
este pedido proporciona meios de cultura de células e métodos de cultura de células melhorados compreendendo n-acetilcisteína. estes meios de cultura de células e métodos de cultura de células melhorados aumentam a viabilidade das células, taxa de crescimento celular e/ou reduzem o tempo de duplicação das células de células auxotróficas de colesterol, células de mieloma, e células de hibridoma.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201462013699P | 2014-06-18 | 2014-06-18 | |
PCT/US2015/036169 WO2015195758A1 (en) | 2014-06-18 | 2015-06-17 | Cell culture methods and media comprising n-acetylcysteine |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112016027797A2 true BR112016027797A2 (pt) | 2017-10-31 |
Family
ID=54936063
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112016027797A BR112016027797A2 (pt) | 2014-06-18 | 2015-06-17 | métodos e meios de cultura de células compreendendo n-acetilcisteína |
Country Status (14)
Country | Link |
---|---|
US (3) | US20170204362A1 (pt) |
EP (1) | EP3158077B1 (pt) |
JP (4) | JP2017518064A (pt) |
KR (2) | KR20220119179A (pt) |
CN (1) | CN106715707A (pt) |
AU (3) | AU2015277230A1 (pt) |
BR (1) | BR112016027797A2 (pt) |
CA (1) | CA2952241A1 (pt) |
ES (1) | ES2947286T3 (pt) |
IL (1) | IL249202A0 (pt) |
MX (1) | MX2016015785A (pt) |
RU (1) | RU2017101195A (pt) |
SG (2) | SG11201609980TA (pt) |
WO (1) | WO2015195758A1 (pt) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108697730A (zh) | 2015-12-18 | 2018-10-23 | 泰佳医疗公司 | 细胞糖胺聚糖组合物及其制备和使用方法 |
EP3492582A1 (en) | 2017-12-01 | 2019-06-05 | UCB Biopharma SPRL | Cell culture methods |
US20220305049A1 (en) * | 2019-08-27 | 2022-09-29 | Tega Therapeutics, Inc. | Heparin and heparan sulfate from modified mst cells and methods of making and using |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4927762A (en) * | 1986-04-01 | 1990-05-22 | Cell Enterprises, Inc. | Cell culture medium with antioxidant |
US5892019A (en) | 1987-07-15 | 1999-04-06 | The United States Of America, As Represented By The Department Of Health And Human Services | Production of a single-gene-encoded immunoglobulin |
US5859205A (en) * | 1989-12-21 | 1999-01-12 | Celltech Limited | Humanised antibodies |
CN1096540A (zh) * | 1993-06-15 | 1994-12-21 | 中国科学院化工冶金研究所 | 气升式悬浮微载体培养贴壁依赖细胞 |
US20030119185A1 (en) | 2000-02-24 | 2003-06-26 | Xcyte Therapies, Inc. | Activation and expansion of cells |
US7501231B2 (en) * | 2001-03-23 | 2009-03-10 | University Of Ottawa | Methods and compositions for cryopreservation of dissociated primary animal cells |
US20030096414A1 (en) | 2001-03-27 | 2003-05-22 | Invitrogen Corporation | Culture medium for cell growth and transfection |
AU2003226065B2 (en) | 2002-04-12 | 2009-02-26 | Ludwig Institute For Cancer Research, Ltd | Recombinant anti-interleukin-9 antibodies |
KR101044538B1 (ko) * | 2002-09-05 | 2011-06-27 | 버베리안 노딕 에이/에스 | 무혈청 조건하에서 일차세포의 배양 및 바이러스의 증식방법 |
KR20050088118A (ko) | 2002-12-13 | 2005-09-01 | 세로고스 | 배양 배지 조성물, 배양 방법, 및 얻어진 근원세포, 및그들의 용도 |
CN100402660C (zh) * | 2002-12-23 | 2008-07-16 | 布里斯托尔-迈尔斯斯奎布公司 | 用于蛋白质生产的哺乳动物细胞培养方法中产物质量提高 |
CA2521826C (en) | 2003-04-11 | 2013-08-06 | Jennifer L. Reed | Recombinant il-9 antibodies and uses thereof |
GB0407315D0 (en) * | 2003-07-15 | 2004-05-05 | Cambridge Antibody Tech | Human antibody molecules |
MXPA06000258A (es) * | 2003-07-15 | 2006-07-03 | Cambridge Antibody Tech | Moleculas de anticuerpo humano para interleucina-13. |
DK1711528T3 (da) * | 2003-12-23 | 2012-08-20 | Genentech Inc | Behandling af cancer med hidtil ukendte anti-il 13 monoklonale antistoffer |
NZ575328A (en) * | 2006-09-13 | 2012-06-29 | Abbott Lab | Cell culture improvements |
US20110262965A1 (en) * | 2010-04-23 | 2011-10-27 | Life Technologies Corporation | Cell culture medium comprising small peptides |
IE20110008A1 (en) | 2011-01-12 | 2012-08-01 | Patrick Thomas Prendergast | Compositions for alleviating:- stress, anxiety, depression and aiding with weight loss |
-
2015
- 2015-06-17 KR KR1020227028044A patent/KR20220119179A/ko not_active Application Discontinuation
- 2015-06-17 WO PCT/US2015/036169 patent/WO2015195758A1/en active Application Filing
- 2015-06-17 SG SG11201609980TA patent/SG11201609980TA/en unknown
- 2015-06-17 JP JP2016573817A patent/JP2017518064A/ja active Pending
- 2015-06-17 KR KR1020177001566A patent/KR102434588B1/ko active IP Right Grant
- 2015-06-17 US US15/318,798 patent/US20170204362A1/en not_active Abandoned
- 2015-06-17 CN CN201580032159.4A patent/CN106715707A/zh active Pending
- 2015-06-17 BR BR112016027797A patent/BR112016027797A2/pt not_active Application Discontinuation
- 2015-06-17 CA CA2952241A patent/CA2952241A1/en not_active Abandoned
- 2015-06-17 AU AU2015277230A patent/AU2015277230A1/en not_active Abandoned
- 2015-06-17 MX MX2016015785A patent/MX2016015785A/es unknown
- 2015-06-17 EP EP15809573.7A patent/EP3158077B1/en active Active
- 2015-06-17 SG SG10201811177SA patent/SG10201811177SA/en unknown
- 2015-06-17 RU RU2017101195A patent/RU2017101195A/ru not_active Application Discontinuation
- 2015-06-17 ES ES15809573T patent/ES2947286T3/es active Active
-
2016
- 2016-11-24 IL IL249202A patent/IL249202A0/en unknown
-
2019
- 2019-07-09 AU AU2019204934A patent/AU2019204934B2/en active Active
- 2019-11-11 US US16/679,713 patent/US11555175B2/en active Active
-
2020
- 2020-05-27 JP JP2020091887A patent/JP2020146051A/ja active Pending
- 2020-10-27 AU AU2020260408A patent/AU2020260408A1/en not_active Abandoned
-
2021
- 2021-12-22 JP JP2021207929A patent/JP2022046609A/ja active Pending
-
2022
- 2022-06-23 US US17/808,410 patent/US20230057856A1/en active Pending
-
2023
- 2023-12-08 JP JP2023207563A patent/JP2024035242A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
EP3158077A4 (en) | 2018-01-17 |
US20170204362A1 (en) | 2017-07-20 |
IL249202A0 (en) | 2017-01-31 |
KR20170020482A (ko) | 2017-02-22 |
RU2017101195A (ru) | 2018-07-20 |
MX2016015785A (es) | 2017-04-25 |
AU2019204934B2 (en) | 2020-11-12 |
WO2015195758A1 (en) | 2015-12-23 |
JP2017518064A (ja) | 2017-07-06 |
KR20220119179A (ko) | 2022-08-26 |
CN106715707A (zh) | 2017-05-24 |
JP2022046609A (ja) | 2022-03-23 |
SG11201609980TA (en) | 2016-12-29 |
JP2020146051A (ja) | 2020-09-17 |
EP3158077A1 (en) | 2017-04-26 |
SG10201811177SA (en) | 2019-01-30 |
AU2019204934A1 (en) | 2019-07-25 |
JP2024035242A (ja) | 2024-03-13 |
RU2017101195A3 (pt) | 2019-02-19 |
US11555175B2 (en) | 2023-01-17 |
CA2952241A1 (en) | 2015-12-23 |
ES2947286T3 (es) | 2023-08-04 |
EP3158077B1 (en) | 2023-04-05 |
US20230057856A1 (en) | 2023-02-23 |
US20200208100A1 (en) | 2020-07-02 |
KR102434588B1 (ko) | 2022-08-22 |
AU2015277230A1 (en) | 2017-01-05 |
AU2020260408A1 (en) | 2020-11-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
|
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
B11B | Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements |