AR096629A1 - Métodos para analizar composiciones de cisteamina - Google Patents
Métodos para analizar composiciones de cisteaminaInfo
- Publication number
- AR096629A1 AR096629A1 ARP140102286A ARP140102286A AR096629A1 AR 096629 A1 AR096629 A1 AR 096629A1 AR P140102286 A ARP140102286 A AR P140102286A AR P140102286 A ARP140102286 A AR P140102286A AR 096629 A1 AR096629 A1 AR 096629A1
- Authority
- AR
- Argentina
- Prior art keywords
- compositions
- cysteamine
- methods
- cisteamine
- analyze
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 3
- UFULAYFCSOUIOV-UHFFFAOYSA-N cysteamine Chemical compound NCCS UFULAYFCSOUIOV-UHFFFAOYSA-N 0.000 abstract 4
- 229960003151 mercaptamine Drugs 0.000 abstract 4
- WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 abstract 3
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
- 239000000523 sample Substances 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 238000004458 analytical method Methods 0.000 abstract 1
- 239000000872 buffer Substances 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 238000010828 elution Methods 0.000 abstract 1
- 239000012535 impurity Substances 0.000 abstract 1
- 238000002347 injection Methods 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
- 238000005259 measurement Methods 0.000 abstract 1
- 238000004007 reversed phase HPLC Methods 0.000 abstract 1
- 239000012488 sample solution Substances 0.000 abstract 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/62—Detectors specially adapted therefor
- G01N30/74—Optical detectors
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/32—Bonded phase chromatography
- B01D15/325—Reversed phase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
- G01N21/33—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using ultraviolet light
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/04—Preparation or injection of sample to be analysed
- G01N30/06—Preparation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/04—Preparation or injection of sample to be analysed
- G01N30/16—Injection
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/15—Medicinal preparations ; Physical properties thereof, e.g. dissolubility
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N2030/022—Column chromatography characterised by the kind of separation mechanism
- G01N2030/027—Liquid chromatography
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
- G01N2030/8809—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
- G01N2030/8813—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials
- G01N2030/8818—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials involving amino acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
- G01N30/28—Control of physical parameters of the fluid carrier
- G01N30/34—Control of physical parameters of the fluid carrier of fluid composition, e.g. gradient
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/17—Nitrogen containing
- Y10T436/173845—Amine and quaternary ammonium
Landscapes
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Pathology (AREA)
- Immunology (AREA)
- General Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Se describen métodos de análisis de la pureza de composiciones que comprenden cisteamina y detección de impurezas en composiciones de cisteamina. Reivindicación 1: Un método de análisis de la pureza de una composición que comprende cisteamina, caracterizado porque comprende: (i) inyección de una solución de muestra que comprende cisteamina en una columna de HPLC en fase inversa; (ii) elución de la muestra de la columna usando una fase móvil que comprende un ácido alquilsulfónico, un tampón, acetonitrilo y metanol; y (iii) medición de la muestra eluida usando un detector UV en una longitud de onda de aproximadamente 170 nm a aproximadamente 250 nm.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361835987P | 2013-06-17 | 2013-06-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR096629A1 true AR096629A1 (es) | 2016-01-20 |
Family
ID=52105169
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP140102286A AR096629A1 (es) | 2013-06-17 | 2014-06-16 | Métodos para analizar composiciones de cisteamina |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US9435785B2 (es) |
| EP (1) | EP3011312B8 (es) |
| JP (1) | JP6518658B2 (es) |
| AR (1) | AR096629A1 (es) |
| CA (1) | CA2914674C (es) |
| ES (1) | ES2931310T3 (es) |
| HK (1) | HK1224012A1 (es) |
| IL (1) | IL242843B (es) |
| MX (1) | MX370192B (es) |
| PL (1) | PL3011312T3 (es) |
| TW (1) | TWI659209B (es) |
| WO (1) | WO2014204887A1 (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109633055B (zh) * | 2018-12-29 | 2023-01-13 | 贵州长生药业有限责任公司 | 杀菌止痒洗剂多成分含量测定方法 |
| US11782040B1 (en) * | 2023-05-12 | 2023-10-10 | Michele Glinn | Cannabis potency testing method |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6050186B2 (ja) * | 1980-07-15 | 1985-11-07 | 三井東圧化学株式会社 | ２−メルカプトエチルアミンハロゲン化水素酸塩類の製造法 |
| US5011608A (en) * | 1988-11-18 | 1991-04-30 | Dragana Damjanovic | Biogenic amine assay using HPLC-ECD |
| US5256362A (en) * | 1989-07-14 | 1993-10-26 | Nippon Shokubai Co., Ltd. | Method for production of granular cysteamine hydrochloride |
| WO1997014711A1 (en) * | 1995-10-19 | 1997-04-24 | Receptagen Corporation | Vitamin b12 receptor modulating agents and methods related thereto |
| JP3523207B2 (ja) * | 2000-02-14 | 2004-04-26 | ファイザー・プロダクツ・インク | ＲＰ−ＨＰＬＣカラムを介してのＬｏｇＰ係数の測定 |
| PT1531794T (pt) * | 2002-06-28 | 2017-09-14 | Civitas Therapeutics Inc | Epinefrina inalável |
| US20050250838A1 (en) * | 2004-05-04 | 2005-11-10 | Challapalli Prasad V | Formulation for sustained delivery |
| EP1893632B1 (en) * | 2005-06-17 | 2015-08-12 | Novo Nordisk Health Care AG | Selective reduction and derivatization of engineered factor vii proteins comprising at least one non-native cysteine |
| WO2007089670A2 (en) * | 2006-01-27 | 2007-08-09 | The Regents Of The University Of California | Enterically coated cysteamine, cystamine and derivatives thereof |
| WO2007092331A2 (en) * | 2006-02-02 | 2007-08-16 | Esa Biosciences, Inc. | Detection methods and devices |
| SG138487A1 (en) * | 2006-06-19 | 2008-01-28 | Singapore Polytechnic | Method for catalysing a fusion polypeptide undergoing a cleavage reaction |
| US20080103169A1 (en) * | 2006-10-27 | 2008-05-01 | The Curators Of The University Of Missouri | Compositions comprising acid labile proton pump inhibiting agents, at least one other pharmaceutically active agent and methods of using same |
| SG176525A1 (en) * | 2006-12-22 | 2011-12-29 | Sigma Tau Ind Farmaceuti | Gel useful for the delivery of ophthalmic drugs |
| US20080206883A1 (en) | 2007-02-26 | 2008-08-28 | Cody Laboratories, Inc. | Hplc method for separation and detection of hydromorphone and related opioid pharmacophores |
| JP2010133807A (ja) * | 2008-12-03 | 2010-06-17 | Dainippon Sumitomo Pharma Co Ltd | 錠剤の粉砕方法およびこれをもちいた錠剤成分の分析方法 |
| PT2464655T (pt) * | 2009-08-11 | 2017-05-25 | Biocon Ltd | Processos cromatográficos |
| CA2732440C (en) * | 2011-02-23 | 2017-10-31 | Universite Laval | Cystamine analogues for the treatment of parkinson`s disease |
| CN103018359B (zh) | 2012-11-30 | 2014-06-11 | 华南理工大学 | 一种测定食品或蔬菜中草酸含量的方法 |
| AR096628A1 (es) * | 2013-06-17 | 2016-01-20 | Raptor Pharmaceuticals Inc | Formulación en perlas de cisteamina de liberación retardada y métodos de preparación y uso de ella |
-
2014
- 2014-06-16 TW TW103120754A patent/TWI659209B/zh active
- 2014-06-16 AR ARP140102286A patent/AR096629A1/es active IP Right Grant
- 2014-06-17 ES ES14814315T patent/ES2931310T3/es active Active
- 2014-06-17 JP JP2016521492A patent/JP6518658B2/ja active Active
- 2014-06-17 EP EP14814315.9A patent/EP3011312B8/en active Active
- 2014-06-17 WO PCT/US2014/042616 patent/WO2014204887A1/en active Application Filing
- 2014-06-17 CA CA2914674A patent/CA2914674C/en active Active
- 2014-06-17 MX MX2015017413A patent/MX370192B/es active IP Right Grant
- 2014-06-17 PL PL14814315.9T patent/PL3011312T3/pl unknown
- 2014-06-17 US US14/306,820 patent/US9435785B2/en active Active
-
2015
- 2015-11-30 IL IL242843A patent/IL242843B/en not_active IP Right Cessation
-
2016
- 2016-08-05 US US15/229,777 patent/US20160341706A1/en not_active Abandoned
- 2016-10-21 HK HK16112155.8A patent/HK1224012A1/zh unknown
-
2018
- 2018-01-02 US US15/860,461 patent/US20180292366A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US9435785B2 (en) | 2016-09-06 |
| HK1224012A1 (zh) | 2017-08-11 |
| JP2016523364A (ja) | 2016-08-08 |
| JP6518658B2 (ja) | 2019-05-22 |
| MX2015017413A (es) | 2016-06-21 |
| EP3011312B8 (en) | 2022-11-02 |
| TW201534920A (zh) | 2015-09-16 |
| PL3011312T3 (pl) | 2023-04-11 |
| EP3011312B1 (en) | 2022-09-28 |
| MX370192B (es) | 2019-12-04 |
| EP3011312A1 (en) | 2016-04-27 |
| TWI659209B (zh) | 2019-05-11 |
| US20160341706A1 (en) | 2016-11-24 |
| CA2914674C (en) | 2019-08-27 |
| WO2014204887A1 (en) | 2014-12-24 |
| IL242843B (en) | 2019-01-31 |
| ES2931310T3 (es) | 2022-12-28 |
| CA2914674A1 (en) | 2014-12-24 |
| EP3011312A4 (en) | 2017-01-25 |
| US20180292366A1 (en) | 2018-10-11 |
| US20150056712A1 (en) | 2015-02-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration |