SG138487A1 - Method for catalysing a fusion polypeptide undergoing a cleavage reaction - Google Patents

Method for catalysing a fusion polypeptide undergoing a cleavage reaction

Info

Publication number
SG138487A1
SG138487A1 SG200604173-5A SG2006041735A SG138487A1 SG 138487 A1 SG138487 A1 SG 138487A1 SG 2006041735 A SG2006041735 A SG 2006041735A SG 138487 A1 SG138487 A1 SG 138487A1
Authority
SG
Singapore
Prior art keywords
fusion polypeptide
cleavage reaction
catalysing
undergoing
reaction
Prior art date
Application number
SG200604173-5A
Inventor
Cui Taian
Puah Chum Mok
Liew Oi Wah
Lee Siew Hui
Original Assignee
Singapore Polytechnic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Singapore Polytechnic filed Critical Singapore Polytechnic
Priority to SG200604173-5A priority Critical patent/SG138487A1/en
Priority to PCT/SG2007/000169 priority patent/WO2007149053A1/en
Publication of SG138487A1 publication Critical patent/SG138487A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/63—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from plants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/12—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by hydrolysis, i.e. solvolysis in general
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/50—Fusion polypeptide containing protease site

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Botany (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

There is disclosed a method of increasing the reaction rate of a fusion polypeptide undergoing a cleavage reaction. The method comprises the step of providing an oxidant to a reactant solution of the fusion polypeptide as it undergoes the cleavage reaction to increase the rate of the reaction.
SG200604173-5A 2006-06-19 2006-06-19 Method for catalysing a fusion polypeptide undergoing a cleavage reaction SG138487A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
SG200604173-5A SG138487A1 (en) 2006-06-19 2006-06-19 Method for catalysing a fusion polypeptide undergoing a cleavage reaction
PCT/SG2007/000169 WO2007149053A1 (en) 2006-06-19 2007-06-19 Method for catalysing a fusion polypeptide undergoing a cleavage reaction

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SG200604173-5A SG138487A1 (en) 2006-06-19 2006-06-19 Method for catalysing a fusion polypeptide undergoing a cleavage reaction

Publications (1)

Publication Number Publication Date
SG138487A1 true SG138487A1 (en) 2008-01-28

Family

ID=38833698

Family Applications (1)

Application Number Title Priority Date Filing Date
SG200604173-5A SG138487A1 (en) 2006-06-19 2006-06-19 Method for catalysing a fusion polypeptide undergoing a cleavage reaction

Country Status (2)

Country Link
SG (1) SG138487A1 (en)
WO (1) WO2007149053A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI659209B (en) * 2013-06-17 2019-05-11 地平線罕見醫學製藥有限責任公司 Methods for analyzing cysteamine compositions

Also Published As

Publication number Publication date
WO2007149053A1 (en) 2007-12-27

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