AR090566A1 - Proceso para la produccion de inhibidores de crr - Google Patents
Proceso para la produccion de inhibidores de crrInfo
- Publication number
- AR090566A1 AR090566A1 ARP130101059A ARP130101059A AR090566A1 AR 090566 A1 AR090566 A1 AR 090566A1 AR P130101059 A ARP130101059 A AR P130101059A AR P130101059 A ARP130101059 A AR P130101059A AR 090566 A1 AR090566 A1 AR 090566A1
- Authority
- AR
- Argentina
- Prior art keywords
- formula
- inhibitors
- crr
- production
- alkyl
- Prior art date
Links
- 239000003112 inhibitor Substances 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 4
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 2
- OCQAXYHNMWVLRH-UHFFFAOYSA-N 2,3-dibenzoyl-2,3-dihydroxybutanedioic acid Chemical compound C=1C=CC=CC=1C(=O)C(O)(C(O)=O)C(O)(C(=O)O)C(=O)C1=CC=CC=C1 OCQAXYHNMWVLRH-UHFFFAOYSA-N 0.000 abstract 1
- 102100024167 C-C chemokine receptor type 3 Human genes 0.000 abstract 1
- 101710149862 C-C chemokine receptor type 3 Proteins 0.000 abstract 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 abstract 1
- 150000001450 anions Chemical group 0.000 abstract 1
- 230000001419 dependent effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Cephalosporin Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Silver Salt Photography Or Processing Solution Therefor (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12162852 | 2012-04-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR090566A1 true AR090566A1 (es) | 2014-11-19 |
Family
ID=47998462
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP130101059A AR090566A1 (es) | 2012-04-02 | 2013-03-27 | Proceso para la produccion de inhibidores de crr |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US8680280B2 (OSRAM) |
| EP (1) | EP2834229B1 (OSRAM) |
| JP (1) | JP6255550B2 (OSRAM) |
| AR (1) | AR090566A1 (OSRAM) |
| DK (1) | DK2834229T3 (OSRAM) |
| ES (1) | ES2641862T3 (OSRAM) |
| TW (1) | TW201400474A (OSRAM) |
| UY (1) | UY34719A (OSRAM) |
| WO (1) | WO2013149926A1 (OSRAM) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8278302B2 (en) | 2009-04-08 | 2012-10-02 | Boehringer Ingelheim International Gmbh | Substituted piperidines as CCR3 antagonists |
| UA109290C2 (uk) | 2010-10-07 | 2015-08-10 | Спільні кристали і солі інгібіторів ccr3 | |
| US8680280B2 (en) | 2012-04-02 | 2014-03-25 | Boehringer Ingelheim International Gmbh | Process for the manufacturing of CRR inhibitors |
| US10213421B2 (en) | 2012-04-04 | 2019-02-26 | Alkahest, Inc. | Pharmaceutical formulations comprising CCR3 antagonists |
| BR112019020798A2 (pt) | 2017-04-05 | 2020-04-28 | Alkahest Inc | métodos e composições para tratamento de danos associados ao envelhecimento usando inibidores de ccr3 |
| JP7179755B2 (ja) | 2017-04-05 | 2022-11-29 | アルカヘスト インコーポレイテッド | Ｃｃｒ３阻害剤を使用した網膜関連疾患を治療するための方法および組成物 |
| US11426399B2 (en) | 2018-05-15 | 2022-08-30 | Alkahest, Inc. | Treatment of aging-associated disease with modulators of leukotriene A4 hydrolase |
| US11957671B2 (en) | 2021-11-01 | 2024-04-16 | Alkahest, Inc. | Benzodioxane modulators of leukotriene A4 hydrolase (LTA4H) for prevention and treatment of aging-associated diseases |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE7907121L (sv) | 1979-08-27 | 1981-02-28 | Astra Laekemedel Ab | Ftalimidinderivat |
| JP2807577B2 (ja) | 1990-06-15 | 1998-10-08 | エーザイ株式会社 | 環状アミド誘導体 |
| JPH08134041A (ja) * | 1994-11-10 | 1996-05-28 | Fuji Photo Film Co Ltd | ピラゾールアミド類の製造方法 |
| US6433165B1 (en) | 1998-01-21 | 2002-08-13 | Millennium Pharmaceuticals, Inc. | Chemokine receptor antagonists and methods of use therefor |
| CA2319781A1 (en) | 1998-02-02 | 1999-08-05 | Liping Wang | Cyclic amine modulators of chemokine receptor activity |
| US6140349A (en) | 1998-02-02 | 2000-10-31 | Merck & Co., Inc. | Cyclic amine modulators of chemokine receptor activity |
| ATE428422T1 (de) | 2004-02-05 | 2009-05-15 | Schering Corp | Piperidin-derivate als ccr3-antagonisten |
| JP2006137718A (ja) | 2004-11-12 | 2006-06-01 | Astellas Pharma Inc | インドール若しくはインダゾール誘導体 |
| US8030003B2 (en) | 2004-12-07 | 2011-10-04 | Children's Hospital Medical Center | Diagnosis of eosinophilic esophagitis based on presence of an elevated level of eotaxin-3 |
| DOP2006000051A (es) | 2005-02-24 | 2006-08-31 | Lilly Co Eli | Inhibidores de vegf-r2 y métodos |
| JP2009533416A (ja) | 2006-04-12 | 2009-09-17 | ファイザー・リミテッド | ケモカインｃｃｒ５受容体の調節剤としてのピロリジン誘導体 |
| GB0701992D0 (en) | 2007-02-02 | 2007-03-14 | 7Tm Pharma As | Grehlin Receptor Modulators |
| US8008092B2 (en) | 2007-10-09 | 2011-08-30 | University Of Kentucky Research Foundation | CCR3 inhibition for ocular angiogenesis and macular degeneration |
| TW201000446A (en) | 2008-05-30 | 2010-01-01 | Astrazeneca Ab | New compounds useful in pain therapy |
| US8278302B2 (en) | 2009-04-08 | 2012-10-02 | Boehringer Ingelheim International Gmbh | Substituted piperidines as CCR3 antagonists |
| UA109290C2 (uk) | 2010-10-07 | 2015-08-10 | Спільні кристали і солі інгібіторів ccr3 | |
| US8680280B2 (en) | 2012-04-02 | 2014-03-25 | Boehringer Ingelheim International Gmbh | Process for the manufacturing of CRR inhibitors |
| US20130261153A1 (en) | 2012-04-03 | 2013-10-03 | Boehringer Ingelheim International Gmbh | Use of ccr3-inhibitors |
| US10213421B2 (en) | 2012-04-04 | 2019-02-26 | Alkahest, Inc. | Pharmaceutical formulations comprising CCR3 antagonists |
-
2013
- 2013-03-27 US US13/851,547 patent/US8680280B2/en active Active
- 2013-03-27 AR ARP130101059A patent/AR090566A1/es unknown
- 2013-03-28 WO PCT/EP2013/056638 patent/WO2013149926A1/en not_active Ceased
- 2013-03-28 JP JP2015503828A patent/JP6255550B2/ja active Active
- 2013-03-28 DK DK13712567.0T patent/DK2834229T3/da active
- 2013-03-28 EP EP13712567.0A patent/EP2834229B1/en active Active
- 2013-03-28 ES ES13712567.0T patent/ES2641862T3/es active Active
- 2013-04-01 TW TW102111742A patent/TW201400474A/zh unknown
- 2013-04-02 UY UY0001034719A patent/UY34719A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| UY34719A (es) | 2013-10-31 |
| TW201400474A (zh) | 2014-01-01 |
| WO2013149926A1 (en) | 2013-10-10 |
| JP2015516959A (ja) | 2015-06-18 |
| DK2834229T3 (da) | 2017-11-20 |
| US20130261307A1 (en) | 2013-10-03 |
| ES2641862T3 (es) | 2017-11-14 |
| EP2834229A1 (en) | 2015-02-11 |
| EP2834229B1 (en) | 2017-08-09 |
| US8680280B2 (en) | 2014-03-25 |
| JP6255550B2 (ja) | 2018-01-10 |
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| IN2014DN10440A (OSRAM) |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |