UY34719A - Proceso para la producción de inhibidores de crr - Google Patents

Proceso para la producción de inhibidores de crr

Info

Publication number
UY34719A
UY34719A UY0001034719A UY34719A UY34719A UY 34719 A UY34719 A UY 34719A UY 0001034719 A UY0001034719 A UY 0001034719A UY 34719 A UY34719 A UY 34719A UY 34719 A UY34719 A UY 34719A
Authority
UY
Uruguay
Prior art keywords
crr
inhibitors
production
pág
escanear
Prior art date
Application number
UY0001034719A
Other languages
English (en)
Inventor
Duran Adil
Schmid Rolf
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of UY34719A publication Critical patent/UY34719A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Silver Salt Photography Or Processing Solution Therefor (AREA)
  • Cephalosporin Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

La presente invención se refiere a un proceso para preparar inhibidores de CCR3 de la fórmula 1en donde R1 es H, alquilo C1-6, alquil C0-4-cicloalqui lo C3-6, haloalquilo C1-6; R2 es H, alquilo C1-6; X es un anión seleccionado del grupo que consiste en cloruro o ½ dibenzoiltartrato j es 1 ó 2.
UY0001034719A 2012-04-02 2013-04-02 Proceso para la producción de inhibidores de crr UY34719A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP12162852 2012-04-02

Publications (1)

Publication Number Publication Date
UY34719A true UY34719A (es) 2013-10-31

Family

ID=47998462

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001034719A UY34719A (es) 2012-04-02 2013-04-02 Proceso para la producción de inhibidores de crr

Country Status (9)

Country Link
US (1) US8680280B2 (es)
EP (1) EP2834229B1 (es)
JP (1) JP6255550B2 (es)
AR (1) AR090566A1 (es)
DK (1) DK2834229T3 (es)
ES (1) ES2641862T3 (es)
TW (1) TW201400474A (es)
UY (1) UY34719A (es)
WO (1) WO2013149926A1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8278302B2 (en) 2009-04-08 2012-10-02 Boehringer Ingelheim International Gmbh Substituted piperidines as CCR3 antagonists
UA109290C2 (uk) 2010-10-07 2015-08-10 Спільні кристали і солі інгібіторів ccr3
AR090566A1 (es) 2012-04-02 2014-11-19 Boehringer Ingelheim Int Proceso para la produccion de inhibidores de crr
US10213421B2 (en) 2012-04-04 2019-02-26 Alkahest, Inc. Pharmaceutical formulations comprising CCR3 antagonists
UA125658C2 (uk) 2017-04-05 2022-05-11 Алкахест Інк. Спосіб та композиція для лікування захворювання, пов'язаного з сітківкою ока, з використанням інгібітора ccr3
SG11201909245PA (en) 2017-04-05 2019-11-28 Alkahest Inc Methods and compositions for treating aging-associated impairments using ccr3-inhibitors
SG11202010115RA (en) 2018-05-15 2020-11-27 Alkahest Inc Treatment of aging-associated disease with modulators of leukotriene a4 hydrolase
EP4426284A1 (en) 2021-11-01 2024-09-11 Alkahest, Inc. Benzodioxane modulators of leukotriene a4 hydrolase (lta4h) for prevention and treatment of aging-associated diseases

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE7907121L (sv) 1979-08-27 1981-02-28 Astra Laekemedel Ab Ftalimidinderivat
JP2807577B2 (ja) 1990-06-15 1998-10-08 エーザイ株式会社 環状アミド誘導体
JPH08134041A (ja) * 1994-11-10 1996-05-28 Fuji Photo Film Co Ltd ピラゾールアミド類の製造方法
AU2335699A (en) 1998-01-21 1999-08-09 Kyowa Hakko Kogyo Co. Ltd. Chemokine receptor antagonists and methods of use therefor
US6140349A (en) 1998-02-02 2000-10-31 Merck & Co., Inc. Cyclic amine modulators of chemokine receptor activity
CA2319781A1 (en) 1998-02-02 1999-08-05 Liping Wang Cyclic amine modulators of chemokine receptor activity
ES2324224T3 (es) 2004-02-05 2009-08-03 Schering Corporation Derivados de piperidina que se pueden utilizar como antagonistas ccr3.
JP2006137718A (ja) 2004-11-12 2006-06-01 Astellas Pharma Inc インドール若しくはインダゾール誘導体
US8030003B2 (en) 2004-12-07 2011-10-04 Children's Hospital Medical Center Diagnosis of eosinophilic esophagitis based on presence of an elevated level of eotaxin-3
DOP2006000051A (es) 2005-02-24 2006-08-31 Lilly Co Eli Inhibidores de vegf-r2 y métodos
EP2059515A2 (en) 2006-04-12 2009-05-20 Pfizer Limited Pyrrolidine derivatives as modulators of chemokine ccr5 receptors
GB0701992D0 (en) 2007-02-02 2007-03-14 7Tm Pharma As Grehlin Receptor Modulators
US8008092B2 (en) 2007-10-09 2011-08-30 University Of Kentucky Research Foundation CCR3 inhibition for ocular angiogenesis and macular degeneration
TW201000446A (en) 2008-05-30 2010-01-01 Astrazeneca Ab New compounds useful in pain therapy
US8278302B2 (en) 2009-04-08 2012-10-02 Boehringer Ingelheim International Gmbh Substituted piperidines as CCR3 antagonists
UA109290C2 (uk) 2010-10-07 2015-08-10 Спільні кристали і солі інгібіторів ccr3
AR090566A1 (es) 2012-04-02 2014-11-19 Boehringer Ingelheim Int Proceso para la produccion de inhibidores de crr
US20130261153A1 (en) 2012-04-03 2013-10-03 Boehringer Ingelheim International Gmbh Use of ccr3-inhibitors
US10213421B2 (en) 2012-04-04 2019-02-26 Alkahest, Inc. Pharmaceutical formulations comprising CCR3 antagonists

Also Published As

Publication number Publication date
ES2641862T3 (es) 2017-11-14
AR090566A1 (es) 2014-11-19
TW201400474A (zh) 2014-01-01
EP2834229A1 (en) 2015-02-11
WO2013149926A1 (en) 2013-10-10
JP2015516959A (ja) 2015-06-18
US8680280B2 (en) 2014-03-25
DK2834229T3 (da) 2017-11-20
US20130261307A1 (en) 2013-10-03
EP2834229B1 (en) 2017-08-09
JP6255550B2 (ja) 2018-01-10

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