ES2641862T3 - Proceso para la elaboración de inhibidores de CCR3 - Google Patents

Proceso para la elaboración de inhibidores de CCR3 Download PDF

Info

Publication number
ES2641862T3
ES2641862T3 ES13712567.0T ES13712567T ES2641862T3 ES 2641862 T3 ES2641862 T3 ES 2641862T3 ES 13712567 T ES13712567 T ES 13712567T ES 2641862 T3 ES2641862 T3 ES 2641862T3
Authority
ES
Spain
Prior art keywords
elaboration
ccr3 inhibitors
ccr3
inhibitors
image
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES13712567.0T
Other languages
English (en)
Inventor
Adil Duran
Rolf Schmid
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alkahest Inc
Original Assignee
Alkahest Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alkahest Inc filed Critical Alkahest Inc
Application granted granted Critical
Publication of ES2641862T3 publication Critical patent/ES2641862T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Cephalosporin Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Silver Salt Photography Or Processing Solution Therefor (AREA)

Description

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Claims (1)

  1. imagen1
    imagen2
ES13712567.0T 2012-04-02 2013-03-28 Proceso para la elaboración de inhibidores de CCR3 Active ES2641862T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12162852 2012-04-02
EP12162852 2012-04-02
PCT/EP2013/056638 WO2013149926A1 (en) 2012-04-02 2013-03-28 Process for the manufacturing of ccr3 inhibitors

Publications (1)

Publication Number Publication Date
ES2641862T3 true ES2641862T3 (es) 2017-11-14

Family

ID=47998462

Family Applications (1)

Application Number Title Priority Date Filing Date
ES13712567.0T Active ES2641862T3 (es) 2012-04-02 2013-03-28 Proceso para la elaboración de inhibidores de CCR3

Country Status (9)

Country Link
US (1) US8680280B2 (es)
EP (1) EP2834229B1 (es)
JP (1) JP6255550B2 (es)
AR (1) AR090566A1 (es)
DK (1) DK2834229T3 (es)
ES (1) ES2641862T3 (es)
TW (1) TW201400474A (es)
UY (1) UY34719A (es)
WO (1) WO2013149926A1 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8278302B2 (en) 2009-04-08 2012-10-02 Boehringer Ingelheim International Gmbh Substituted piperidines as CCR3 antagonists
UA109290C2 (uk) 2010-10-07 2015-08-10 Спільні кристали і солі інгібіторів ccr3
US8680280B2 (en) 2012-04-02 2014-03-25 Boehringer Ingelheim International Gmbh Process for the manufacturing of CRR inhibitors
US10213421B2 (en) 2012-04-04 2019-02-26 Alkahest, Inc. Pharmaceutical formulations comprising CCR3 antagonists
BR112019020798A2 (pt) 2017-04-05 2020-04-28 Alkahest Inc métodos e composições para tratamento de danos associados ao envelhecimento usando inibidores de ccr3
ES3046717T3 (en) 2017-04-05 2025-12-02 Alkahest Inc Compounds and pharmaceutical compositions for use in treating retina-associated disease using ccr3-inhibitors
US11426399B2 (en) 2018-05-15 2022-08-30 Alkahest, Inc. Treatment of aging-associated disease with modulators of leukotriene A4 hydrolase
US20230312697A1 (en) 2020-06-11 2023-10-05 Alkahest Inc. Methods of improving retina-associated disease outcome using ccr3-inhibitors
AU2022376563A1 (en) 2021-11-01 2023-12-07 Alkahest, Inc. Benzodioxane modulators of leukotriene a4 hydrolase (lta4h) for prevention and treatment of aging-associated diseases

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE7907121L (sv) 1979-08-27 1981-02-28 Astra Laekemedel Ab Ftalimidinderivat
JP2807577B2 (ja) 1990-06-15 1998-10-08 エーザイ株式会社 環状アミド誘導体
JPH08134041A (ja) * 1994-11-10 1996-05-28 Fuji Photo Film Co Ltd ピラゾールアミド類の製造方法
AU2335699A (en) 1998-01-21 1999-08-09 Kyowa Hakko Kogyo Co. Ltd. Chemokine receptor antagonists and methods of use therefor
US6140349A (en) 1998-02-02 2000-10-31 Merck & Co., Inc. Cyclic amine modulators of chemokine receptor activity
AU2654399A (en) 1998-02-02 1999-08-16 Merck & Co., Inc. Cyclic amine modulators of chemokine receptor activity
DE602005013931D1 (es) 2004-02-05 2009-05-28 Schering Corp
JP2006137718A (ja) 2004-11-12 2006-06-01 Astellas Pharma Inc インドール若しくはインダゾール誘導体
WO2006083390A2 (en) 2004-12-07 2006-08-10 Children's Hospital Medical Center Eotaxin-3 in eosinophilic esophagitis
DOP2006000051A (es) 2005-02-24 2006-08-31 Lilly Co Eli Inhibidores de vegf-r2 y métodos
WO2007116313A2 (en) 2006-04-12 2007-10-18 Pfizer Limited Pyrrolidine derivatives as modulators of chemokine ccr5 receptors
GB0701992D0 (en) 2007-02-02 2007-03-14 7Tm Pharma As Grehlin Receptor Modulators
US8008092B2 (en) 2007-10-09 2011-08-30 University Of Kentucky Research Foundation CCR3 inhibition for ocular angiogenesis and macular degeneration
TW201000446A (en) 2008-05-30 2010-01-01 Astrazeneca Ab New compounds useful in pain therapy
US8278302B2 (en) 2009-04-08 2012-10-02 Boehringer Ingelheim International Gmbh Substituted piperidines as CCR3 antagonists
UA109290C2 (uk) 2010-10-07 2015-08-10 Спільні кристали і солі інгібіторів ccr3
US8680280B2 (en) 2012-04-02 2014-03-25 Boehringer Ingelheim International Gmbh Process for the manufacturing of CRR inhibitors
US20130261153A1 (en) 2012-04-03 2013-10-03 Boehringer Ingelheim International Gmbh Use of ccr3-inhibitors
US10213421B2 (en) 2012-04-04 2019-02-26 Alkahest, Inc. Pharmaceutical formulations comprising CCR3 antagonists

Also Published As

Publication number Publication date
EP2834229A1 (en) 2015-02-11
TW201400474A (zh) 2014-01-01
WO2013149926A1 (en) 2013-10-10
UY34719A (es) 2013-10-31
AR090566A1 (es) 2014-11-19
JP6255550B2 (ja) 2018-01-10
US8680280B2 (en) 2014-03-25
US20130261307A1 (en) 2013-10-03
JP2015516959A (ja) 2015-06-18
DK2834229T3 (da) 2017-11-20
EP2834229B1 (en) 2017-08-09

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