AR088513A1 - Inmunoenlazantes dirigidos contra esclerostina - Google Patents

Inmunoenlazantes dirigidos contra esclerostina

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Publication number
AR088513A1
AR088513A1 ARP120103978A ARP120103978A AR088513A1 AR 088513 A1 AR088513 A1 AR 088513A1 AR P120103978 A ARP120103978 A AR P120103978A AR P120103978 A ARP120103978 A AR P120103978A AR 088513 A1 AR088513 A1 AR 088513A1
Authority
AR
Argentina
Prior art keywords
sclerostin
sclerostine
immuno
linkers
tnf
Prior art date
Application number
ARP120103978A
Other languages
English (en)
Spanish (es)
Inventor
Hsieh Chung
Ming-Ivanov Alexander
Waegell Wendy
Original Assignee
Abbvie Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbvie Inc filed Critical Abbvie Inc
Publication of AR088513A1 publication Critical patent/AR088513A1/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
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    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
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CN104203978A (zh) 2014-12-10
US20130171096A1 (en) 2013-07-04
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TW201323440A (zh) 2013-06-16
CA2853258A1 (en) 2013-05-02
US20150266977A1 (en) 2015-09-24
SG11201401791WA (en) 2014-08-28
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JP2014533659A (ja) 2014-12-15
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