AR081247A1 - Tratamiento de enfermedades relacionadas con metionina sulfoxido reductasa a (msra) mediante la inhibicion de la transcripcion antisentido natural para msra - Google Patents

Tratamiento de enfermedades relacionadas con metionina sulfoxido reductasa a (msra) mediante la inhibicion de la transcripcion antisentido natural para msra

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Publication number
AR081247A1
AR081247A1 ARP110101797A ARP110101797A AR081247A1 AR 081247 A1 AR081247 A1 AR 081247A1 AR P110101797 A ARP110101797 A AR P110101797A AR P110101797 A ARP110101797 A AR P110101797A AR 081247 A1 AR081247 A1 AR 081247A1
Authority
AR
Argentina
Prior art keywords
disease
msra
disorder
disorder associated
oligonucleotide
Prior art date
Application number
ARP110101797A
Other languages
English (en)
Spanish (es)
Original Assignee
Opko Curna Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Opko Curna Llc filed Critical Opko Curna Llc
Publication of AR081247A1 publication Critical patent/AR081247A1/es

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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
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    • A61K31/713—Double-stranded nucleic acids or oligonucleotides
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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    • A—HUMAN NECESSITIES
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    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1136—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against growth factors, growth regulators, cytokines, lymphokines or hormones
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    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0051—Oxidoreductases (1.) acting on a sulfur group of donors (1.8)
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    • C12Y108/00—Oxidoreductases acting on sulfur groups as donors (1.8)
    • C12Y108/04—Oxidoreductases acting on sulfur groups as donors (1.8) with a disulfide as acceptor (1.8.4)
    • C12Y108/04011—Peptide-methionine (S)-S-oxide reductase (1.8.4.11)
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    • C12N2330/00—Production
    • C12N2330/10—Production naturally occurring

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ARP110101797A 2010-05-26 2011-05-26 Tratamiento de enfermedades relacionadas con metionina sulfoxido reductasa a (msra) mediante la inhibicion de la transcripcion antisentido natural para msra AR081247A1 (es)

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US34865010P 2010-05-26 2010-05-26

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AR081247A1 true AR081247A1 (es) 2012-07-18

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ARP110101797A AR081247A1 (es) 2010-05-26 2011-05-26 Tratamiento de enfermedades relacionadas con metionina sulfoxido reductasa a (msra) mediante la inhibicion de la transcripcion antisentido natural para msra

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US (2) US8980858B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP2576784B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JP5917497B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (1) KR101902197B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CN (1) CN102971423B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AR (1) AR081247A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA2799596C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK2576784T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES2664585T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (1) NO2576784T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
RU (1) RU2620978C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SA (1) SA111320488B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
TW (1) TWI575068B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
WO (1) WO2011150007A2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

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EA201492120A1 (ru) 2012-05-16 2015-10-30 Рана Терапьютикс, Инк. Композиции и способы для модулирования экспрессии atp2a2
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WO2013173652A1 (en) 2012-05-16 2013-11-21 Rana Therapeutics, Inc. Compositions and methods for modulating gene expression
WO2016070060A1 (en) 2014-10-30 2016-05-06 The General Hospital Corporation Methods for modulating atrx-dependent gene repression
EP3271460A4 (en) 2015-03-17 2019-03-13 The General Hospital Corporation RNA INTERACTOM OF POLYCOMB REPRESSIVE COMPLEX 1 (PRC1)
WO2019112489A1 (en) * 2017-12-05 2019-06-13 Limited Liability Company "Gero" Methods and agents for treatment of aging and aging related conditions and diseases
CN110551731B (zh) * 2019-08-09 2023-04-14 深圳大学 一种白鳍鲨的MsrA基因、蛋白质与基因提取的方法

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ES2664585T3 (es) 2018-04-20
WO2011150007A2 (en) 2011-12-01
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