AR080525A1 - Un proceso usando reactivos de grignard - Google Patents

Un proceso usando reactivos de grignard

Info

Publication number
AR080525A1
AR080525A1 ARP110100825A ARP110100825A AR080525A1 AR 080525 A1 AR080525 A1 AR 080525A1 AR P110100825 A ARP110100825 A AR P110100825A AR P110100825 A ARP110100825 A AR P110100825A AR 080525 A1 AR080525 A1 AR 080525A1
Authority
AR
Argentina
Prior art keywords
formula
compound
alkyl
group
alkynyl
Prior art date
Application number
ARP110100825A
Other languages
English (en)
Original Assignee
Basf Se
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Se filed Critical Basf Se
Publication of AR080525A1 publication Critical patent/AR080525A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
    • A01N43/647—Triazoles; Hydrogenated triazoles
    • A01N43/653—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N55/00—Biocides, pest repellants or attractants, or plant growth regulators, containing organic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen and sulfur
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F3/00—Compounds containing elements of Groups 2 or 12 of the Periodic Table
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F3/00—Compounds containing elements of Groups 2 or 12 of the Periodic Table
    • C07F3/003—Compounds containing elements of Groups 2 or 12 of the Periodic Table without C-Metal linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F3/00—Compounds containing elements of Groups 2 or 12 of the Periodic Table
    • C07F3/02—Magnesium compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Plant Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Agronomy & Crop Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pest Control & Pesticides (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)

Abstract

Un proceso usando reactivos de Grignard para proporcionar compuestos que contienen grupo tio-triazoIo. Reivindicacion 1: Un proceso caracterizado porque es para la preparacion de un compuesto (3a) que comprende la etapa de: (i) hacer reaccionar un compuesto de triazolo de la formula (4) con un reactivo de Grignard R1MgQ (5), en donde las variables se definen de la siguiente manera: R es un grupo orgánico; Q es R1 o X, en donde X es halogeno; y R1 es alquilo C1-10, alquenilo C2-10, alquinilo C2-10, cicloalquilo C3-8 o arilo C6-10, en donde el arilo no está sustituido o está sustituido con uno, dos o tres grupos seleccionados, de modo independiente, del grupo que consiste en halogeno y alquilo C1-4. Reivindicacion 2: Un proceso para la preparacion de un compuesto con contenido de un grupo tio-triazolo caracterizado por la formula (1) que comprende ya sea la etapa (ii) junto con (iii-1) o (iii-2); o que comprende la etapa (iv); (ii) hacer reaccionar un compuesto de la formula (3a) con azufre, a fin de obtener un compuesto de la formula (2a) y (iii-1) protonar dicho compuesto de la formula (2a), a fin de obtener los compuestos de la formula (1), en donde Y es hidrogeno; o (iii-2) hacer reaccionar dicho compuesto de la formula (2a) con un compuesto electrofílico; Y1-LG a fin de obtener los compuestos de la formula (1), en donde Y es Y1, en donde Y1 es alquilo C1-8, haloalquilo C1-8, alquenilo C2-8, haloalquenilo C2-8, alquinilo C2-8, haloalquinilo C2-8, C(=S)R9, SO2R10 o CN; en donde R9 y R10 son como se definen a continuacion; y LG es un grupo saliente; o (iv) hacer reaccionar un compuesto de la formula (3a) con un electrofilo seleccionado de (VI) un disulfuro R2-S-S-R2, a fin de obtener un compuesto de la formula (1), en donde Y es R2; (VII) R3-S-SO2-R3, a fin de obtener un compuesto de la formula (1), en donde Y es R3 o (VIII) R4-S-Hal, en donde Hal es halogeno, a fin de obtener un compuesto de la formula (1), en donde Y es R4; en donde R y Q son como se definen en la reivindicacion 1 y las demás variables tienen los siguientes significados: Y es hidrogeno, halogeno, alquilo C1-8, haloalquilo C1-8, alquenilo C2-8, haloalquenilo C2-8, alquinilo C2-8, haloalquinilo C2-8, arilo C6-10, un heterociclo aromático de cinco, seis, siete, ocho, nueve o diez miembros que contiene uno, dos, tres o cuatro heteroátomos del grupo que consiste en O, N y S, C(=S)R9, SO2R10 o CN; en donde R9 es NA3A4 en donde A3, A4 son, de modo independiente entre sí, hidrogeno, alquilo C1-8, haloalquilo C1-8, alquenilo C2-8, haloalquenilo C2-8, alquinilo C2-8, haloalquinilo C2-8, cicloalquilo C3-8, halocicloalquilo C3-8, cicloalquenilo C3-8, halocicloalquenilo C3-8, arilo C6-10, un heterociclo aromático de cinco, seis, siete, ocho, nueve o diez miembros que contiene uno, dos, tres o cuatro heteroátomos del grupo que consiste en O, N y S; R10 es alquilo C1-8, fenil-alquilo C1-8 o fenilo, donde los grupos fenilo están en cada caso no sustituidos o sustituidos con uno, dos o tres grupos seleccionados, de modo independiente, del grupo que consiste en halogeno y alquilo C1-4; R2, R3 son, de modo independiente entre sí, alquilo C1-8, haloalquilo C1-8, alquenilo C2-8, haloalquenilo C2-8, alquinilo C2-8, haloalquinilo C2-5, arilo C6-10, un heterociclo aromático de cinco, seis, siete, ocho, nueve o diez miembros que contiene uno, dos, tres o cuatro heteroátomos del grupo que consiste en O, N y S, C(=S)R9 o CN; y R4 es halogeno, alquilo C1-8, haloalquilo C1-8, alquenilo C2-8, haloalquenilo C2-8, alquinilo C2-8, haloalquinilo C2-8, arilo C6-10 o un heterociclo aromático de cinco, seis, siete, ocho, nueve o diez miembros que contiene uno, dos, tres o cuatro heteroátomos del grupo que consiste en O, N y S o CN.
ARP110100825A 2010-03-16 2011-03-15 Un proceso usando reactivos de grignard AR080525A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP10156601 2010-03-16
EP10159510 2010-04-09

Publications (1)

Publication Number Publication Date
AR080525A1 true AR080525A1 (es) 2012-04-11

Family

ID=43901138

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP110100825A AR080525A1 (es) 2010-03-16 2011-03-15 Un proceso usando reactivos de grignard

Country Status (15)

Country Link
US (2) US8729272B2 (es)
EP (1) EP2547687B1 (es)
JP (1) JP2013522268A (es)
KR (1) KR20130034020A (es)
CN (1) CN102791720B (es)
AR (1) AR080525A1 (es)
AU (1) AU2011229200A1 (es)
BR (1) BR112012023157B1 (es)
CA (1) CA2791606A1 (es)
CL (1) CL2012002464A1 (es)
CR (1) CR20120444A (es)
EA (1) EA201201288A1 (es)
MX (1) MX2012009805A (es)
WO (1) WO2011113820A1 (es)
ZA (1) ZA201207676B (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013167633A1 (en) 2012-05-09 2013-11-14 Basf Se Acrylamide compounds for combating invertebrate pests
WO2013182433A1 (en) * 2012-06-05 2013-12-12 Basf Se A process using grignard reagents
EP2746256A1 (en) 2012-12-19 2014-06-25 Basf Se Fungicidal imidazolyl and triazolyl compounds
EP2746255A1 (en) 2012-12-19 2014-06-25 Basf Se Substituted [1,2,4]triazole and imidazole compounds
WO2014095249A1 (en) 2012-12-19 2014-06-26 Basf Se Fungicidal imidazolyl and triazolyl compounds
EP2746277A1 (en) 2012-12-19 2014-06-25 Basf Se Fungicidal imidazolyl and triazolyl compounds
EP2746279A1 (en) 2012-12-19 2014-06-25 Basf Se Fungicidal imidazolyl and triazolyl compounds
WO2014095381A1 (en) 2012-12-19 2014-06-26 Basf Se Fungicidal imidazolyl and triazolyl compounds
EP2746264A1 (en) 2012-12-19 2014-06-25 Basf Se Substituted [1,2,4]triazole and imidazole compounds
EP2746259A1 (en) 2012-12-21 2014-06-25 Basf Se Substituted [1,2,4]triazole and imidazole compounds
EP2746257A1 (en) 2012-12-21 2014-06-25 Basf Se Substituted [1,2,4]triazole and imidazole compounds
EP2746260A1 (en) 2012-12-21 2014-06-25 Basf Se Substituted [1,2,4]triazole and imidazole compounds
EP2746258A1 (en) 2012-12-21 2014-06-25 Basf Se Substituted [1,2,4]triazole and imidazole compounds
JP2016522800A (ja) 2013-04-12 2016-08-04 バイエル・クロップサイエンス・アクチェンゲゼルシャフト 新規トリアゾリンチオン誘導体
WO2018054832A1 (en) 2016-09-22 2018-03-29 Bayer Cropscience Aktiengesellschaft Novel triazole derivatives
CN110267946A (zh) * 2016-11-18 2019-09-20 美国陶氏益农公司 4-((6-(2-(2,4-二氟苯基)-1,1-二氟-2-羟基-3-(5-巯基-1h-1,2,4-三唑-1-基)丙基)吡啶-3-基)氧基)苄腈及制备方法
PL3541794T3 (pl) * 2016-11-18 2022-01-17 Corteva Agriscience Llc 4-((6-(2-(2,4-difluorofenylo)-1,1-difluoro-2-hydroksy-3-(5-merkapto-1h-1,2,4-triazol-1- ilo)propylo)pirydyn-3-ylo)oksy)benzonitryl i sposoby wytwarzania
CN109952294A (zh) * 2016-11-18 2019-06-28 美国陶氏益农公司 4-((6-(2-(2,4-二氟苯基)-1,1-二氟-2-羟基-3-(5-巯基-1h-1,2,4-三唑-1-基)丙基)吡啶-3-基)氧基)苄腈及制备方法
EP3541795A4 (en) * 2016-11-18 2020-04-29 Dow AgroSciences LLC PROCESSES FOR THE PREPARATION OF 4 - ((6- (2,4-DIFLUOROPHENYL) -1,1-DIFLUORO-2-HYDROXY-3 (5-MERCAPTO-1H-1,2,4-TRIAZOL-1-YL) PROPYL) PYRIDIN-3-YL) OXY) BENZONITRILE
CN106674138B (zh) * 2016-11-21 2018-11-27 河南科技大学 一种戊唑醇新型半抗原及其合成方法和应用
MX2019009310A (es) 2017-02-08 2019-12-09 Bayer Ag Derivados de triazoletiona.
WO2019171160A1 (en) * 2018-03-06 2019-09-12 Upl Ltd A process for preparation of fungicidally active triazole compounds
CN109232363B (zh) * 2018-09-21 2021-08-13 安徽理工大学 一种3-硒氰基吲哚化合物的合成方法
US11002177B2 (en) 2018-11-15 2021-05-11 Caterpillar Inc. System and method for staged pre-chamber purging

Family Cites Families (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4414210A (en) 1979-10-02 1983-11-08 Rohm And Haas Company 2-Hydroxyarylethyltriazole fungicides
DE3337937A1 (de) 1982-10-28 1984-05-03 Sandoz-Patent-GmbH, 7850 Lörrach Neue azolderivate
DE3315681A1 (de) 1983-04-29 1984-10-31 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von oxiranen
DE3601927A1 (de) 1986-01-23 1987-07-30 Basf Ag Alpha, beta-substituierte acroleine, verfahren zu deren herstellung und deren verwendung
CA2006309C (fr) 1988-12-29 2001-12-18 Jean Hutt Azolylmethylcyclopentane benzylidene fongicide
DE3907729A1 (de) 1989-03-10 1990-09-13 Basf Ag Trifluormethylphenylazolylmethyloxirane, verfahren zu ihrer herstellung und deren verwendung als pflanzenschutzmittel
US5268517A (en) 1989-07-14 1993-12-07 Basf Aktiengesellschaft Stereoselective preparation of Z-1,2-diarylallyl chlorides and the conversion thereof into azolylmethyloxiranes, and novel intermediates
JP2975058B2 (ja) 1989-07-18 1999-11-10 ビーエーエスエフ アクチェンゲゼルシャフト 新規のｚ―１，２―ジアリール―アリルクロリド及びその立体配置選択的製造方法ならびにこれから製造される新規のクロルメチル―ジアリール―オキシラン
IL95493A0 (en) 1989-09-09 1991-06-30 Basf Ag Azolylmethyloxiranes,their manufacture and their use as fungicides
DE4030039A1 (de) 1990-09-22 1992-03-26 Bayer Ag Verfahren zur herstellung von 2-(1-chlor-cyclopropyl)-1- (2-chlor-phenyl)-3-(1,2,4-triazol-1-yl- propan-2-ol
JPH07138234A (ja) 1993-11-11 1995-05-30 Kureha Chem Ind Co Ltd アゾリルメチルシクロアルカノール誘導体の製造方法
DE19528046A1 (de) 1994-11-21 1996-05-23 Bayer Ag Triazolyl-Derivate
DE19520097A1 (de) 1995-06-01 1996-12-05 Bayer Ag Triazolylmethyl-oxirane
DE19520098A1 (de) 1995-06-01 1996-12-05 Bayer Ag Triazolylmethyl-cyclopentanole
DE19521487A1 (de) 1995-06-13 1996-12-19 Bayer Ag Mercapto-triazolyl-dioxacycloalkane
DE19528300A1 (de) 1995-08-02 1997-02-06 Bayer Ag 2-Phenylethyl-mercapto-triazole
DE19529089A1 (de) 1995-08-08 1997-02-13 Bayer Ag Mercapto-triazolyl-nitrile
DE19529091A1 (de) 1995-08-08 1997-02-13 Bayer Ag Mercapto-triazolyl-ketone
DE19617282A1 (de) 1996-04-30 1997-11-06 Bayer Ag Triazolyl-mercaptide
DE19617461A1 (de) 1996-05-02 1997-11-06 Bayer Ag Acylmercapto-triazolyl-Derivate
DE19619544A1 (de) 1996-05-15 1997-11-20 Bayer Ag Triazolyl-Disulfide
DE19620590A1 (de) 1996-05-22 1997-11-27 Bayer Ag Sulfonyl-mercapto-triazolyl-Derivate
DE19732033A1 (de) 1997-07-25 1999-01-28 Bayer Ag Triazolinthion-phosphorsäure-Derivate
DE19744706A1 (de) 1997-10-10 1999-04-15 Bayer Ag Verfahren zur Herstellung von Triazolinthion-Derivaten
IL135316A (en) 1997-10-24 2003-05-29 Bayer Ag Oxiranyl-triazoline thiones, their preparation and microbicidal compositions comprising them
US6041122A (en) 1998-02-27 2000-03-21 Intel Corporation Method and apparatus for hiding crytographic keys utilizing autocorrelation timing encoding and computation
WO2005056548A1 (en) 2003-12-11 2005-06-23 Cheminova A/S Enantiomerically pure epoxiconazole and its use as crop protection agent
EP1810974A1 (en) * 2006-01-18 2007-07-25 Ludwig-Maximilians-Universität München Preparation and use of magnesium amides
WO2008083070A1 (en) * 2006-12-29 2008-07-10 Neurogen Corporation Crf1 receptor ligands comprising fused bicyclic heteroaryl moieties
KR20100093127A (ko) 2007-12-19 2010-08-24 바스프 에스이 아졸릴메틸옥시란, 이의 용도 및 이를 포함하는 작용제
WO2009077497A2 (de) 2007-12-19 2009-06-25 Basf Se Azolylmethyloxirane, ihre verwendung sowie sie enthaltende mittel
US20100273651A1 (en) 2007-12-19 2010-10-28 Basf Se Azolylmethyloxiranes, use Thereof and Agents Containing the Same
EP2224812A2 (de) 2007-12-19 2010-09-08 Basf Se Azolylmethyloxirane, ihre verwendung sowie sie enthaltende mittel
EP2328878A1 (de) 2008-09-09 2011-06-08 Basf Se Triazolverbindungen, ihre verwendung sowie sie enthaltende mittel
WO2010029002A1 (de) 2008-09-09 2010-03-18 Basf Se Triazolverbindungen, ihre verwendung sowie sie enthaltende mittel
BRPI0918230A2 (pt) 2008-09-09 2015-12-08 Basf Se composto, composição de composto ativo, método para controlar fungos fitopatogênicos, medicamento, e, método para preparar um antimicótico
WO2010029003A1 (de) 2008-09-09 2010-03-18 Basf Se Triazolverbindungen, ihre verwendung sowie sie enthaltende mittel
BRPI0918990A2 (pt) 2008-09-22 2015-09-22 Basf Se composto, combinação de composto ativo, semente, processo para combater fungos fitopatogênicos, medicamento, e, processo para prepara um antimicótico.
WO2010031721A1 (de) 2008-09-22 2010-03-25 Basf Se Imidazol- und triazolverbindungen, ihre verwendung sowie sie enthaltende mittel
WO2010031842A1 (de) 2008-09-22 2010-03-25 Basf Se Imidazol- und triazolverbindungen, ihre verwendung sowie sie enthaltende mittel
US20110172097A1 (en) 2008-09-22 2011-07-14 Basf Se Imidazole and Triazole Compounds, Their Use and Agents Containing The Same
CN102177143A (zh) 2008-10-07 2011-09-07 巴斯夫欧洲公司 三唑和咪唑化合物、其应用和含有它们的试剂
US20110190122A1 (en) 2008-10-07 2011-08-04 Basf Se Triazole and Imidazole Compounds, Use Thereof and Agents Containing Them
WO2011069912A1 (de) 2009-12-07 2011-06-16 Basf Se Triazolverbindungen, ihre verwendung sowie sie enthaltende mittel
WO2011069916A1 (de) 2009-12-08 2011-06-16 Basf Se Triazolverbindungen, ihre verwendung als fungizide sowie sie enthaltende mittel
WO2011069894A1 (de) 2009-12-08 2011-06-16 Basf Se Triazolverbindungen, ihre verwendung sowie sie enthaltende mittel
BR112012015040A2 (pt) 2009-12-18 2015-09-22 Basf Se processo para a preparação de grupos tio-triazol substituídos da fórmula geral (i) e compostos (lla)

Also Published As

Publication number Publication date
US20140206884A1 (en) 2014-07-24
AU2011229200A1 (en) 2012-10-11
BR112012023157B1 (pt) 2018-08-07
JP2013522268A (ja) 2013-06-13
EP2547687B1 (en) 2015-07-01
EA201201288A1 (ru) 2013-04-30
US20130005985A1 (en) 2013-01-03
BR112012023157A2 (pt) 2016-05-31
CN102791720B (zh) 2015-04-29
CL2012002464A1 (es) 2013-01-11
MX2012009805A (es) 2012-09-12
CA2791606A1 (en) 2011-09-22
US9167817B2 (en) 2015-10-27
CR20120444A (es) 2012-10-04
ZA201207676B (en) 2013-12-23
KR20130034020A (ko) 2013-04-04
US8729272B2 (en) 2014-05-20
EP2547687A1 (en) 2013-01-23
WO2011113820A1 (en) 2011-09-22
CN102791720A (zh) 2012-11-21

Similar Documents

Publication Publication Date Title
AR080525A1 (es) Un proceso usando reactivos de grignard
AR052568A1 (es) Derivados de pirazolo -pirimidina como antagonstas de mglur2
AR054560A1 (es) Espiropiperidina como inhibidores de beta-secretasa para el tratamiento de la enfermedad de alzheimer
CO6300861A2 (es) Compuestos inhibidores de dipeptidil peptidasa iv metodos de preparacion de los mismos y composiciones farmaceuticas que los contienen como agentes activos
CO6270309A2 (es) Inhibidores tetrahidropiranocromeno de gamma secretasa
AR075717A1 (es) Compuestos de 3- aril quinazolin -4- ona para combatir plagas de invertebrados
CO6612267A2 (es) Nuevos derivados de 1,1 dióxido- 5 fenil- 2,3,4-5tetrahidro- 1,4-benzotiazepina y composiciones farmaceúticas que los comprenden
AR079224A1 (es) Compuestos insecticidas basados en derivados de isoxazolina
CO6190521A2 (es) Derivados de azacicloalcanos como inhibidores de estearoil-coenzima a delta -9 desaturasa
PE20141191A1 (es) Compuestos como inhibidores de bace
AR072545A1 (es) Fenilpirazinonas como inhibidores de la btk, composicion farmaceutica que las contiene y su uso en la fabricacion de un medicamento para el tratamiento de enfermedades autoinmunes e inflamatorias.
EA200970379A1 (ru) Бициклические гетероароматические соединения
AR084011A1 (es) Compuestos nitrogenados heterociclicos utiles para el tratamiento de infecciones por el virus sincitial respiratorio (rsv), proceso para prepararlos y composiciones farmaceuticas que los contienen
AR066107A1 (es) Derivados de triazolopiridin - carboxamidas y triazolopirimidin-carboxamidas, su preparacion y su aplicacion en terapeutica como inhibidores de la enzimamonoacil glicerol lipasa y composiciones qu los contienen.
AR080596A1 (es) Compuestos alquilamido y composiciones farmaceuticas
AR061106A1 (es) Pteridinas sustituidas y composiciones farmaceuticas que las contienen.
BR112013008675A2 (pt) métodos e composições para o tratamento de diabetes e dislipidemia
PE20120657A1 (es) Compuesto para el tratamiento de trastornos metabolicos
BR112012033690A2 (pt) sais de cálcio de compostos como agentes anti-inflamatórios, imunomodulares e antitroliferativos
AR070264A1 (es) Derivados de oxazepinopirimidona heteroarilamida sustituidos
PE20120223A1 (es) Compuestos heterociclicos como inhibidores del transportador de glicina-1 (glyt-1)
AR077510A1 (es) Derivados de dihidroindolonas, su procedimiento de preparacion y las com-posiciones farmaceuticas que los contienen
BR112013010850A8 (pt) Composto de etinilfenilamidina ou sal do mesmo, método para produzir o mesmo e fungicida para uso agrícola e em horticultura
AR061455A1 (es) Acidos fosfinicos y sus derivados de azufre y metodos para su preparacion
AR043427A1 (es) Derivados de acido alcanoico sustituidos con aril-cicloalquilo, procedimientos para su obtencion, y su empleo como medicamentos

Legal Events

Date Code Title Description
FB Suspension of granting procedure