AR065837A1 - Composicion para el tratamiento del sindrome metabolico - Google Patents
Composicion para el tratamiento del sindrome metabolicoInfo
- Publication number
- AR065837A1 AR065837A1 ARP080100202A ARP080100202A AR065837A1 AR 065837 A1 AR065837 A1 AR 065837A1 AR P080100202 A ARP080100202 A AR P080100202A AR P080100202 A ARP080100202 A AR P080100202A AR 065837 A1 AR065837 A1 AR 065837A1
- Authority
- AR
- Argentina
- Prior art keywords
- agent
- composition
- serotonin
- inhibitor
- possesses
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
- A61K31/612—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid
- A61K31/616—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Biomedical Technology (AREA)
- Reproductive Health (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Emergency Medicine (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Child & Adolescent Psychology (AREA)
- Psychology (AREA)
- Heart & Thoracic Surgery (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Una composicion que incluye un primer agente seleccionado del grupo que consiste de un inhibidor de fosforilacion oxidativa, un ionoforo, y un activador de proteínas quinasa activadas por adenosina 5'-monofosfato (AMPK); un segundo agente que poseeactividad anti-inflamatoria; y un tercer agente que posee una actividad serotonina. Reivindicacion 2: La composicion de la reivindicacion 1, en donde el primer agente es metformina, fenformina, buformina, efedrina, tiroxina, salicilanilida, oácido salicílico. Reivindicacion 4: La composicion de la reivindicacion 1, en donde el segundo agente es un compuesto anti-inflamatorio no-esteroide. Reivindicacion 5: La composicion de la reivindicacion 1, en donde el segundo agente esaspirina, diclofenac, ibuprofeno, indometacina, acetaminofeno, nimesulida, o un inhibidor de COX-2. Reivindicacion 7: La composicion de la reivindicacion 1, en donde el tercer agente es serotonina o un inhibidor de la reabsorcion de la serotonina. Reivindicacion 8: La composicion de la reivindicacion 7, en donde el tercer agente es sulfato de serotonina, un complejo de serotonina-creatinina sulfato, o hidrocloruro de serotonina.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US88521207P | 2007-01-16 | 2007-01-16 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR065837A1 true AR065837A1 (es) | 2009-07-08 |
Family
ID=39636359
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP080100202A AR065837A1 (es) | 2007-01-16 | 2008-01-17 | Composicion para el tratamiento del sindrome metabolico |
Country Status (22)
Country | Link |
---|---|
US (1) | US8431552B2 (es) |
EP (2) | EP2494967A1 (es) |
JP (1) | JP5271918B2 (es) |
KR (1) | KR101460820B1 (es) |
CN (1) | CN101631859B (es) |
AR (1) | AR065837A1 (es) |
AU (1) | AU2008206328B2 (es) |
BR (1) | BRPI0806774A2 (es) |
CA (1) | CA2675638C (es) |
DK (1) | DK2118279T3 (es) |
ES (1) | ES2660173T3 (es) |
IL (1) | IL199903A (es) |
MX (1) | MX2009007720A (es) |
MY (1) | MY154869A (es) |
NO (1) | NO2118279T3 (es) |
NZ (1) | NZ578891A (es) |
RU (1) | RU2486902C2 (es) |
SG (1) | SG178716A1 (es) |
TR (1) | TR201802359T4 (es) |
TW (2) | TWI629058B (es) |
WO (1) | WO2008089212A1 (es) |
ZA (1) | ZA200904972B (es) |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007041643A1 (en) * | 2005-10-03 | 2007-04-12 | University Of Tennessee Research Foundation | Dietary calcium for reducing the production of reactive oxygen species |
US20100047177A1 (en) * | 2007-01-26 | 2010-02-25 | Washington University | Methods and compositions for treating neuropathies |
CN103251631A (zh) * | 2008-05-13 | 2013-08-21 | 根梅迪卡治疗公司 | 用于治疗代谢性病症的水杨酸盐(酯)缀合物 |
CA2666036C (en) * | 2008-05-16 | 2017-09-12 | Chien-Hung Chen | Novel compositions and methods for treating hyperproliferative diseases |
WO2010053949A1 (en) * | 2008-11-04 | 2010-05-14 | Metaproteomics, Llc | Phytochemical compositions and methods for activating amp-kinase |
KR100922519B1 (ko) * | 2008-11-12 | 2009-10-20 | 대원제약주식회사 | 펠루비프로펜을 함유하는 용출률 및 안정성이 개선된 경구투여용 약제학적 제제 |
EP2408443A1 (en) * | 2009-03-16 | 2012-01-25 | Genmedica Therapeutics SL | Anti-inflammatory and antioxidant conjugates useful for treating metabolic disorders |
AU2010224867A1 (en) * | 2009-03-16 | 2011-10-06 | Genmedica Therapeutics Sl | Combination therapies for treating metabolic disorders |
AU2010225923B2 (en) * | 2009-03-16 | 2016-10-27 | Ipintl, Llc | Treating Alzheimer's disease and osteoporosis and reducing aging |
US8486922B2 (en) * | 2010-04-28 | 2013-07-16 | Chien-Hung Chen | Composition |
US8466197B2 (en) | 2010-12-14 | 2013-06-18 | Genmedica Therapeutics Sl | Thiocarbonates as anti-inflammatory and antioxidant compounds useful for treating metabolic disorders |
EP2705842A1 (en) * | 2012-09-05 | 2014-03-12 | Pharnext | Therapeutic approaches for treating parkinson's disease |
CN103889411B (zh) | 2011-07-15 | 2018-03-16 | 纽斯尔特科学公司 | 用于调节代谢途径的组合物和方法 |
US9198454B2 (en) | 2012-03-08 | 2015-12-01 | Nusirt Sciences, Inc. | Compositions, methods, and kits for regulating energy metabolism |
BR112014027983B1 (pt) * | 2012-05-08 | 2022-05-24 | Aeromics, Inc | Uso de inibidores de aquaporina seletivos |
WO2014014530A1 (en) * | 2012-07-17 | 2014-01-23 | Mylari Banavara L | Ursolic acid salts for treating diabetes and obesity |
US9636329B2 (en) * | 2012-11-06 | 2017-05-02 | Northwestern University | Methods of treating cancer with glut inhibitors and oxidative phosphorylation inhibitors |
MX2015006023A (es) | 2012-11-13 | 2016-03-31 | Nusirt Sciences Inc | Composiciones y metodos para incrementar el metabolismo energetico. |
US20140314778A1 (en) | 2013-03-13 | 2014-10-23 | Genentech, Inc. | Formulations with reduced oxidation |
AR095399A1 (es) | 2013-03-13 | 2015-10-14 | Genentech Inc | Formulaciones con oxidación reducida, método |
JP6389236B2 (ja) * | 2013-03-13 | 2018-09-12 | ジェネンテック, インコーポレイテッド | 酸化還元製剤 |
WO2014152016A1 (en) | 2013-03-15 | 2014-09-25 | Nusirt Sciences, Inc. | Leucine and nicotinic acid reduces lipid levels |
AU2014227807B2 (en) * | 2013-03-15 | 2018-03-08 | Als Mountain Llc | Pharmaceutical composition comprising an AMPK activator and a serotonergic agent and methods of use thereof |
AU2014346682B2 (en) | 2013-11-06 | 2020-03-12 | Aeromics, Inc. | Novel formulations |
SG11201607075TA (en) | 2014-02-27 | 2016-09-29 | Nusirt Sciences Inc | Compositions and methods for the reduction or prevention of hepatic steatosis |
EP3139910B1 (en) * | 2014-05-05 | 2019-11-27 | The Board of Regents of The University of Texas System | Compositions comprising ursolic acid and/or resveratrol for treating obesity |
US9839644B2 (en) | 2014-09-09 | 2017-12-12 | ARKAY Therapeutics, LLC | Formulations and methods for treatment of metabolic syndrome |
AU2015328044A1 (en) * | 2014-10-01 | 2017-04-20 | Als Mountain Llc | Pharmaceutical composition comprising Aspirin, Metformin, and Serotonin with non-ionic surfactant |
WO2016141279A1 (en) * | 2015-03-04 | 2016-09-09 | Dana-Farber Cancer Institute, Inc. | Salicylate inhibitors of melk and methods of use |
AU2017384392B2 (en) | 2016-12-20 | 2023-05-25 | Lts Lohmann Therapie-Systeme Ag | Transdermal therapeutic system containing asenapine and polysiloxane or polyisobutylene |
PL3338768T3 (pl) | 2016-12-20 | 2020-05-18 | Lts Lohmann Therapie-Systeme Ag | Transdermalny system terapeutyczny zawierający asenapinę |
JP2020525545A (ja) | 2017-06-26 | 2020-08-27 | エルテーエス ローマン テラピー−ジステーメ アーゲー | アセナピンおよびシリコーンアクリルハイブリッドポリマーを含有する経皮治療システム |
MX2020014286A (es) | 2018-06-20 | 2021-03-25 | Lts Lohmann Therapie Systeme Ag | Sistema terapeutico transdermico que contiene asenapina. |
WO2020115765A1 (en) | 2018-12-05 | 2020-06-11 | Celagenex Research (India) Pvt. Ltd. | Novel synergistic composition comprising sirt1 and ampk activators for treating metabolic syndrome |
CN115304595A (zh) * | 2020-01-10 | 2022-11-08 | 康圣博施医药有限公司 | 药物的治疗组合以及其使用方法 |
US20220133700A1 (en) * | 2020-10-29 | 2022-05-05 | Thomas Winston | Compositions and methods for treating neurological disorders |
CN115703772A (zh) * | 2021-08-09 | 2023-02-17 | 天地恒一制药股份有限公司 | 艾拉莫德共晶,及其制备方法与应用 |
Family Cites Families (54)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3914250A (en) | 1974-08-01 | 1975-10-21 | American Home Prod | 1,4-Diazepino{8 6,5,4-jk{9 carbazoles |
US5100919A (en) * | 1984-03-19 | 1992-03-31 | The Rockefeller University | Biguanides and derivatives thereof as inhibitors of advanced glycosylation of a target protein |
US5385915A (en) * | 1990-05-16 | 1995-01-31 | The Rockefeller University | Treatment of amyloidosis associated with Alzheimer disease using modulators of protein phosphorylation |
GB9311132D0 (en) * | 1993-05-28 | 1993-07-14 | Eisai London Res Lab Ltd | Control of cell death |
DE4409411A1 (de) * | 1994-03-18 | 1995-09-28 | Oped Gmbh Orthopaedische Produ | Verpackungsbehälter |
DE69520528T2 (de) * | 1994-06-14 | 2001-09-27 | Raffinerie Tirlemontoise Sa | Verwendung einer Zusammensetzung enthaltend Inulin oder Oligofructose als Antikrebsmittel |
DE9414065U1 (de) | 1994-08-31 | 1994-11-03 | Roehm Gmbh | Thermoplastischer Kunststoff für darmsaftlösliche Arznei-Umhüllungen |
US7048906B2 (en) * | 1995-05-17 | 2006-05-23 | Cedars-Sinai Medical Center | Methods of diagnosing and treating small intestinal bacterial overgrowth (SIBO) and SIBO-related conditions |
US5981168A (en) * | 1998-05-15 | 1999-11-09 | The University Of British Columbia | Method and composition for modulating amyloidosis |
US20040053900A1 (en) * | 1998-12-23 | 2004-03-18 | Pharmacia Corporation | Method of using a COX-2 inhibitor and an aromatase inhibitor as a combination therapy |
DE60039508D1 (de) | 1999-03-19 | 2008-08-28 | Abbott Gmbh & Co Kg | Methoden zur behandlung der essstörungen |
US6589944B1 (en) * | 1999-04-05 | 2003-07-08 | City Of Hope | Breakers of advanced glycation endproducts |
US6495538B2 (en) * | 1999-06-23 | 2002-12-17 | Zinc Therapeutics, Canada Inc. | Zinc ionophores as therapeutic agents |
DE19949319A1 (de) | 1999-10-13 | 2001-06-13 | Ruetgers Vft Ag | Verfahren zur Herstellung von Arylalkylethern |
EP1097716A1 (en) * | 1999-11-03 | 2001-05-09 | Chronolife Inc. | Dietary anti-adiposity food supplements and drugs based on thyrotropin-releasing hormone (TRH) |
GB0001449D0 (en) * | 2000-01-21 | 2000-03-08 | Cortendo Ab | Compositions |
GB0004003D0 (en) | 2000-02-22 | 2000-04-12 | Knoll Ag | Therapeutic agents |
EP1132389A1 (en) | 2000-03-06 | 2001-09-12 | Vernalis Research Limited | New aza-indolyl derivatives for the treatment of obesity |
US6670330B1 (en) | 2000-05-01 | 2003-12-30 | Theodore J. Lampidis | Cancer chemotherapy with 2-deoxy-D-glucose |
US6927223B1 (en) * | 2000-05-26 | 2005-08-09 | Washington State University Research Foundation | Use of serotonin agents for adjunct therapy in the treatment of cancer |
EP1325008B1 (en) | 2000-07-31 | 2005-10-05 | F. Hoffmann-La Roche Ag | Piperazine derivatives |
HUP0302700A3 (en) * | 2000-08-07 | 2005-05-30 | Ranbaxy Signature Llc Princeto | Liquid formulation of metformin and its use |
MXPA03003246A (es) | 2000-10-16 | 2003-06-06 | Hoffmann La Roche | Derivados de indolina y su uso como ligandos del receptor 5-ht2. |
WO2002036596A2 (en) | 2000-11-03 | 2002-05-10 | Wyeth | CYCLOALKYL[b][1,4]DIAZEPINO[6,7,1-hi]INDOLES AND DERIVATIVES |
US20020173549A1 (en) * | 2000-11-08 | 2002-11-21 | Wurtman Richard J. | Compositions and methods for treatment of mild cognitive impairment |
CA2449899C (en) | 2000-11-20 | 2010-04-06 | Biovitrum Ab | Piperazinylpyrazines compounds as antagonists of serotonin 5-ht2 receptor |
NZ525700A (en) | 2000-11-20 | 2004-12-24 | Biovitrum Ab | Piperazinylpyrazine compounds as agonist or antagonist of serotonin 5HT-2 receptor |
GB0030710D0 (en) | 2000-12-15 | 2001-01-31 | Hoffmann La Roche | Piperazine derivatives |
WO2002051844A1 (en) | 2000-12-27 | 2002-07-04 | F. Hoffmann-La Roche Ag | Indole derivatives and their use as 5-ht2b and 5-ht2c receptor ligands |
US20020137787A1 (en) * | 2001-03-21 | 2002-09-26 | Geho W. Blair | Prevention or treatment of complications related to non-insulin dependent diabetes mellitus or type 2 diabetes mellitus |
US6825198B2 (en) | 2001-06-21 | 2004-11-30 | Pfizer Inc | 5-HT receptor ligands and uses thereof |
EP1302465A1 (en) | 2001-10-11 | 2003-04-16 | BRACCO IMAGING S.p.A. | Enhanced substrate imaging by reversible binding to a paramagnetic complex |
PL375442A1 (en) * | 2002-07-18 | 2005-11-28 | Bristol-Myers Squibb Company | Modulators of the glucocorticoid receptor and method |
US20060147947A1 (en) * | 2002-12-04 | 2006-07-06 | Javier Apfeld | AMPK pathway components |
WO2004078113A2 (en) * | 2003-03-04 | 2004-09-16 | Pharmacia Corporation | Treatment and prevention of obesity with cox-2 inhibitors alone or in combination with weight-loss agents |
US7329638B2 (en) * | 2003-04-30 | 2008-02-12 | The Regents Of The University Of Michigan | Drug delivery compositions |
CA2536111A1 (en) * | 2003-07-24 | 2005-02-03 | Wockhardt Limited | Oral compositions for treatment of diseases |
US20050054731A1 (en) | 2003-09-08 | 2005-03-10 | Franco Folli | Multi-system therapy for diabetes, the metabolic syndrome and obesity |
US20080194019A1 (en) | 2003-09-09 | 2008-08-14 | Beth Israel Deaconess Medical Center, Inc. | Tumor Suppressor Lkb1 Kinase Directly Activates Amp-Activated Kinase |
US7244843B2 (en) * | 2003-10-07 | 2007-07-17 | Bristol-Myers Squibb Company | Modulators of serotonin receptors |
US7820702B2 (en) * | 2004-02-04 | 2010-10-26 | Bristol-Myers Squibb Company | Sulfonylpyrrolidine modulators of androgen receptor function and method |
RU2007103178A (ru) * | 2004-06-30 | 2008-08-10 | Комбинаторкс, Инкорпорейтед (Us) | Способы и реагенты для лечения метаболических нарушений |
WO2006021008A2 (en) * | 2004-08-20 | 2006-02-23 | Lind Stuart E | Ionophores as cancer chemotherapeutic agents |
WO2006024488A2 (en) | 2004-08-30 | 2006-03-09 | Interstitial Therapeutics | Medical stent provided with inhibitors of atp synthesis |
US20070105790A1 (en) * | 2004-09-02 | 2007-05-10 | Bionaut Pharmaceuticals, Inc. | Pancreatic cancer treatment using Na+/K+ ATPase inhibitors |
US20080070867A1 (en) | 2005-01-19 | 2008-03-20 | Metabasis Therapeutics, Inc. | 2-Imidazolone and 2-Imidazolidinone Heterocyclic Inhibitors of Tyrosine Phosphatases |
AU2006206274A1 (en) * | 2005-01-20 | 2006-07-27 | Sirtris Pharmaceuticals, Inc. | Use of sirtuin-activating compounds for treating flushing and drug induced weight gain |
US20070149466A1 (en) * | 2005-07-07 | 2007-06-28 | Michael Milburn | Methods and related compositions for treating or preventing obesity, insulin resistance disorders, and mitochondrial-associated disorders |
US20070015839A1 (en) * | 2005-07-14 | 2007-01-18 | Franco Folli | Daily Dosage Regimen for Treating Diabetes, Obesity, Metabolic Syndrome and Polycystic Ovary Syndrome |
JP5543110B2 (ja) * | 2006-01-05 | 2014-07-09 | エッセンシャリス,インク. | カリウムatpチャネルオープナの塩およびその使用 |
CN101395164A (zh) * | 2006-01-10 | 2009-03-25 | 罗伊·J·于 | N-(膦酰基烷基)-氨基酸、其衍生物和组合物以及使用方法 |
JP2009523149A (ja) | 2006-01-12 | 2009-06-18 | ノバルティス アクチエンゲゼルシャフト | mTOR阻害剤および抗葉酸化合物の組み合わせ |
US7659281B2 (en) * | 2006-04-25 | 2010-02-09 | Bristol-Myers Squibb Company | HMG-CoA reductase inhibitors |
CA2666036C (en) * | 2008-05-16 | 2017-09-12 | Chien-Hung Chen | Novel compositions and methods for treating hyperproliferative diseases |
-
2008
- 2008-01-16 ES ES08727718.2T patent/ES2660173T3/es active Active
- 2008-01-16 DK DK08727718.2T patent/DK2118279T3/en active
- 2008-01-16 NO NO08727718A patent/NO2118279T3/no unknown
- 2008-01-16 US US12/014,932 patent/US8431552B2/en not_active Expired - Fee Related
- 2008-01-16 NZ NZ578891A patent/NZ578891A/en unknown
- 2008-01-16 TR TR2018/02359T patent/TR201802359T4/tr unknown
- 2008-01-16 TW TW103110367A patent/TWI629058B/zh not_active IP Right Cessation
- 2008-01-16 AU AU2008206328A patent/AU2008206328B2/en not_active Ceased
- 2008-01-16 TW TW097101643A patent/TWI440456B/zh not_active IP Right Cessation
- 2008-01-16 RU RU2009131065/15A patent/RU2486902C2/ru not_active IP Right Cessation
- 2008-01-16 SG SG2012003323A patent/SG178716A1/en unknown
- 2008-01-16 MY MYPI20092969A patent/MY154869A/en unknown
- 2008-01-16 EP EP12170283A patent/EP2494967A1/en not_active Withdrawn
- 2008-01-16 KR KR1020097016764A patent/KR101460820B1/ko active IP Right Grant
- 2008-01-16 BR BRPI0806774-0A patent/BRPI0806774A2/pt not_active Application Discontinuation
- 2008-01-16 CN CN200880005140.0A patent/CN101631859B/zh active Active
- 2008-01-16 WO PCT/US2008/051123 patent/WO2008089212A1/en active Application Filing
- 2008-01-16 EP EP08727718.2A patent/EP2118279B1/en active Active
- 2008-01-16 MX MX2009007720A patent/MX2009007720A/es unknown
- 2008-01-16 CA CA2675638A patent/CA2675638C/en not_active Expired - Fee Related
- 2008-01-16 ZA ZA200904972A patent/ZA200904972B/xx unknown
- 2008-01-16 JP JP2009546484A patent/JP5271918B2/ja not_active Expired - Fee Related
- 2008-01-17 AR ARP080100202A patent/AR065837A1/es not_active Application Discontinuation
-
2009
- 2009-07-16 IL IL199903A patent/IL199903A/en active IP Right Grant
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AR065837A1 (es) | Composicion para el tratamiento del sindrome metabolico | |
AR072454A1 (es) | Composiciones que comprenden aspirina, metformina y clorhidrato de serotonina y metodos para el tratamiento de enfermedades hiperproliferativas | |
JP2012520883A5 (es) | ||
JP2010013438A5 (ja) | 過剰増殖性疾患を治療するための新規な組成物 | |
CL2009000316A1 (es) | Compuestos derivados de urea de benzomorfanos y sus sales, inhibidores de la enzima 11-beta-hidroxiesteroide deshidrogenasa; procedimiento de preparacion; composicion farmaceutica; y uso para el tratamiento o prevencion de trastornos metabolicos. | |
AR095631A1 (es) | Composición farmacéutica que comprende un activador ampk y un agente de serotonergico y métodos de uso | |
AR051405A1 (es) | Compuestos de 2-carboxamido(3-amino)tiofeno | |
ECSP099608A (es) | Preparacion solida que comprende alogliptina y pioglitazona | |
ES2634562T3 (es) | Métodos y composiciones para tratar hiperuricemia y trastornos metabólicos asociados con hiperuricemia | |
ECSP17013617A (es) | combinación farmacéutica que comprende 3-(3-dimetilamino-1-etil-2-metil-propil)-fenol y nsaid | |
CL2012002522A1 (es) | Composición farmacéutica que comprende un compuesto inhibidor de dpp iv con un grupo amino o una sal del mismo , un primer diluyente , un segundo diluyente ,un aglutinante , un disgregante y un lubricante, útil en el tratamiento de diabetes mellitus. | |
ECSP109979A (es) | Preparación sólida que contiene alogliptina y clorhidrato de metformina | |
CL2022001743A1 (es) | Dosis de gamma-hidroxibutirato (ghb) | |
CL2012002526A1 (es) | Uso de compuestos inhibidores de dpp iv de formula (i) o (ii) o una de sus sales, para el tratamiento de falla cardiaca. | |
CO6321225A2 (es) | Particulas portadoras sólidas para mejorar la procesabilidad de un agente farmacéutico | |
GT200500246A (es) | Combinacion de compuestos organicos | |
CL2008001821A1 (es) | Compuestos derivados de imidazo[2,1-b]-tiazol; composicion farmaceutica que comprende a dicho compuesto; y uso del compuesto para el tratamiento de diabetes, sindrome metabolico, resistencia a la insulina, entre otras. | |
CL2008002430A1 (es) | Compuestos derivados de bencenosulfonamida, inhibidores de catepsina c; composicion farmaceutica que los comprende; y su uso para el tratamiento de la epoc. | |
CL2009001936A1 (es) | Compuestos derivados de piridazina, inhibidores de 11beta-hsd1; composicion farmaceutica; procedimiento de preparacion; y uso en el tratamiento de la diabetes, obesidad, dislipidemia, trastornos de ingestion de comida e hipertension (divisional de solicitud 1720-2006). | |
CL2007003352A1 (es) | Compuestos derivados de heteromonociclos de nitrogeno; composicion farmaceutica que comprende a dicho compuesto; y uso del compuesto para el tratamiento de enfermedades circulatorias, enfermedades metabolicas y/o enfermedades del sistema nervioso cen | |
CR8163A (es) | Composicion farmaceutica que contiene un inhibidor de histona desacetilasa | |
PE20070521A1 (es) | 7-[2-[4-(6-FLUORO-3-METIL-1,2-BENCISOXAZOL-5-IL)-1-PIPERAZINIL]ETIL]-2-(1-PROPINIL)-7H-PIRAZOL-[4,3-E]-[1,2,4]-TRIAZOL-[1,5-C]-PIRIMIDIN-5-AMINA COMO ANTAGONISTA DEL RECEPTOR DE ADENOSINA A2a | |
WO2008112164A3 (en) | Mitochondrial aldehyde dehydrogenase-2 modulators and methods of use thereof | |
DOP2010000134A (es) | Algunos derivados de 2-pirazinona como inhibidores de elastasa de los neutrofilos | |
CO6640335A2 (es) | Tratamiento terapéutico para síndrome metabólico, diabetes de tipo 2, obesidad o prediabetes |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC | Refusal |