AR057212A1 - Composicion de liberacion prolongada del principio activo, su proceso de preparacion y su utilizacion - Google Patents
Composicion de liberacion prolongada del principio activo, su proceso de preparacion y su utilizacionInfo
- Publication number
- AR057212A1 AR057212A1 ARP060105306A ARP060105306A AR057212A1 AR 057212 A1 AR057212 A1 AR 057212A1 AR P060105306 A ARP060105306 A AR P060105306A AR P060105306 A ARP060105306 A AR P060105306A AR 057212 A1 AR057212 A1 AR 057212A1
- Authority
- AR
- Argentina
- Prior art keywords
- coated
- composition
- granulate
- prolonged release
- pharmaceutical
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
- A61K31/285—Arsenic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/26—Iron; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Hematology (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Zoology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La composicion farmacéutica o nutracéutica de liberacion prolongada de un principio activo, como por ejemplo, sulfato ferroso, que comprende al menos un granulado recubierto; estando compuesto dicho granulado recubierto por una partícula que comprende dicho principio activo recubierto por al menos dos capas que comprenden una combinacion de excipientes. También se refiere a un proceso de preparacion de dicha composicion y su utilizacion. Reivindicacion 1: Composicion farmacéutica o nutracéutica que comprende al menos un granulado recubierto, de liberacion prolongada de un principio activo, estando compuesto dicho granulado recubierto por una partícula que comprende dicho principio activo recubierto por al menos dos capas caracterizadas porque comprenden una combinacion de excipientes compuesta: por al menos un copolímero (a) de ésteres del ácido acrílico y del ácido metacrílico que presenta un porcentaje molar de grupos amonio cuaternario inferior o igual al 8%, en asociacion con un segundo copolímero (b) de ésteres del ácido acrílico y del ácido metacrílico que presenta un porcentaje molar de grupos amonio cuaternario superior al 8%, en una proporcion másica (a) / (b) comprendida entre 60/40 y 80/20, y con una cantidad de (a) comprendida entre 2,5% y 5, 0% en peso seco del peso total de la composicion. Reivindicacion 25: Proceso de preparacion de una composicion farmacéutica o nutracéutica segun cualquiera de las reivindicaciones 1 a 17 caracterizado porque comprende las etapas siguientes: 1) recubrimiento del principio activo con una dispersion acuosa de los dos copolímeros (a) y (b), en la que la proporcion másica (a) / (b) está comprendida entre 60/40 y 80/20, y con una cantidad de (a) comprendida entre 2,5% y 5,0% en peso seco del peso total de la composicion; en un mezclador de palas, 2) Granulacion del granulado obtenido en 1); 3) Secado de los granulados obtenidos en 2); 4) Recubrimiento en lecho de aire fluidizado de los granulados secos obtenidos en 3) mediante pulverizacion de una dispersion acuosa de los dos copolímeros (a) y (b), en la que la proporcion másica (a) / (b) está comprendida entre 60/40 y 80/20, y con una cantidad de (a) comprendida entre 3,5% y 5,0% en peso seco del peso total de la composicion; 5) Secado de los granulados recubiertos obtenidos en 4).
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0512189A FR2894143B1 (fr) | 2005-12-01 | 2005-12-01 | Composition a liberation prolongee de l'actif, son procede de preparation et son utilisation. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR057212A1 true AR057212A1 (es) | 2007-11-21 |
Family
ID=36968738
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP060105306A AR057212A1 (es) | 2005-12-01 | 2006-12-01 | Composicion de liberacion prolongada del principio activo, su proceso de preparacion y su utilizacion |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US8834923B2 (es) |
| EP (1) | EP1954251B1 (es) |
| JP (1) | JP5674275B2 (es) |
| KR (1) | KR101332744B1 (es) |
| CN (1) | CN101321520A (es) |
| AR (1) | AR057212A1 (es) |
| AT (1) | ATE548030T1 (es) |
| AU (1) | AU2006319077B2 (es) |
| BR (1) | BRPI0619774B1 (es) |
| CA (1) | CA2632547C (es) |
| DK (1) | DK1954251T3 (es) |
| ES (1) | ES2383760T3 (es) |
| FR (1) | FR2894143B1 (es) |
| IL (1) | IL191758A (es) |
| MA (1) | MA29770B1 (es) |
| NO (1) | NO339720B1 (es) |
| NZ (1) | NZ566783A (es) |
| PL (1) | PL1954251T3 (es) |
| PT (1) | PT1954251E (es) |
| RS (1) | RS52308B (es) |
| RU (1) | RU2414211C2 (es) |
| SI (1) | SI1954251T1 (es) |
| TN (1) | TNSN08152A1 (es) |
| TW (1) | TWI374035B (es) |
| UA (1) | UA93530C2 (es) |
| WO (1) | WO2007063200A1 (es) |
| ZA (1) | ZA200801896B (es) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0613583D0 (en) * | 2006-07-05 | 2006-08-16 | Sericol Ltd | A printing ink |
| CN101912049A (zh) * | 2010-07-27 | 2010-12-15 | 广州市正百饲料科技有限公司 | 包被微量元素预混料及其制备方法 |
| CN103191078B (zh) * | 2012-01-06 | 2018-01-09 | 常州善美药物研究开发中心有限公司 | 一种双膜多药层的高溶解度盐类药物控释片 |
| NL2014348B1 (en) | 2015-02-25 | 2016-10-13 | Univ Delft Tech | Controlled release from particles encapsulated by molecular layer deposition. |
| RU2702690C2 (ru) * | 2015-08-13 | 2019-10-09 | БИОЛИНГУС АйПи ЛЛСи | Способ получения продуктов, содержащих стабилизированные активные вещества, и композиций, содержащих таковые |
| RU2616264C1 (ru) * | 2016-03-28 | 2017-04-13 | Санкт-Петербургское Государственное бюджетное учреждение здравоохранения "Родильный дом N 10" | Способ профилактики железодефицитной анемии у несовершеннолетних беременных женщин |
| RU2623071C1 (ru) * | 2016-09-29 | 2017-06-21 | федеральное государственное бюджетное образовательное учреждение высшего образования "Ставропольский государственный аграрный университет" | Лечебно-профилактический хелатный железосодержащий препарат для сельскохозяйственных животных |
| CN106344534B (zh) * | 2016-09-30 | 2019-07-19 | 广西科技大学 | 硫酸亚铁肠溶滴丸的制备方法 |
| EP3709994A1 (en) * | 2017-11-14 | 2020-09-23 | Pizeta Pharma S.P.A. | Oral administration form comprising an iron-copper mixture and its use as a food supplement |
| CN109999058A (zh) * | 2019-05-22 | 2019-07-12 | 江阴天江药业有限公司 | 一种胶类中药的烊化方法和产品，以及由该产品制得的固体饮料及其制备方法 |
| WO2024006539A1 (en) * | 2022-07-01 | 2024-01-04 | Vitakey Inc. | Nutraceutical particles |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3622487A1 (de) * | 1986-07-02 | 1988-01-14 | Schering Ag | Arzneimittel mit verzoegerter wirkstoffabgabe |
| IE82916B1 (en) * | 1990-11-02 | 2003-06-11 | Elan Corp Plc | Formulations and their use in the treatment of neurological diseases |
| US5286493A (en) * | 1992-01-27 | 1994-02-15 | Euroceltique, S.A. | Stabilized controlled release formulations having acrylic polymer coating |
| US5478577A (en) | 1993-11-23 | 1995-12-26 | Euroceltique, S.A. | Method of treating pain by administering 24 hour oral opioid formulations exhibiting rapid rate of initial rise of plasma drug level |
| DE4332394A1 (de) * | 1993-09-23 | 1995-03-30 | Falk Pharma Gmbh | Budesonid-Pellets mit kontrolliertem Freigabeprofil und Verfahren zu ihrer Herstellung |
| FR2792527B1 (fr) * | 1999-04-22 | 2004-08-13 | Ethypharm Lab Prod Ethiques | Microgranules de ketoprofene, procede de preparation et compositions pharmaceutiques |
| RU2292877C2 (ru) * | 1999-08-31 | 2007-02-10 | Грюненталь Гмбх | Лекарственная ретард-форма, содержащая сахаринат трамадола |
| MXPA02002193A (es) * | 1999-08-31 | 2002-09-30 | Gr Nenthal Gmbh | Forma de administracion de accion retardada que contiene sacarinato de tramadol. |
| WO2001015665A1 (en) * | 1999-09-02 | 2001-03-08 | Nostrum Pharmaceuticals, Inc. | Controlled release oral dosage suitable for oral administration |
| SK287684B6 (sk) | 1999-12-20 | 2011-06-06 | Schering Corporation | Pevná orálna farmaceutická dávková forma s predĺženým uvoľňovaním |
| DE10013029A1 (de) * | 2000-03-17 | 2001-09-20 | Roehm Gmbh | Mehrschichtige Arzneiform für die Colonfreigabe |
| EA200201044A1 (ru) * | 2000-03-31 | 2003-04-24 | Нюкомед Аустриа Гмбх | Фармацевтическая композиция с контролируемым высвобождением, содержащая мидодрин и/или десглимидодрин |
| AR030557A1 (es) * | 2000-04-14 | 2003-08-27 | Jagotec Ag | Una tableta en multicapa de liberacion controlada y metodo de tratamiento |
| KR100477874B1 (ko) | 2001-04-10 | 2005-03-22 | 곽해수 | 지방산에스터를 이용한 수용성 철분 미세캡슐 |
| EP1423092A2 (en) * | 2001-09-05 | 2004-06-02 | Vectura Limited | Functional powders for oral delivery |
| WO2003055475A1 (en) | 2002-01-03 | 2003-07-10 | Lek Pharmaceutical And Chemical Company D.D. | Controlled release pharmaceutical formulation containing venlafaxine |
| US20030190355A1 (en) * | 2002-04-05 | 2003-10-09 | Hermelin Marc S. | Modified release minerals |
| ATE491439T1 (de) * | 2002-08-15 | 2011-01-15 | Euro Celtique Sa | Pharmazeutische zusammensetzungen enthaltend einen opioidantagonisten |
| US6562378B1 (en) * | 2002-08-16 | 2003-05-13 | Tsar Health Private Ltd. | Nutritional supplement for adolescents |
| DE602004028023D1 (de) * | 2003-08-29 | 2010-08-19 | Lifecycle Pharma As | Tacrolimus enthaltende feste dispersionen |
-
2005
- 2005-12-01 FR FR0512189A patent/FR2894143B1/fr active Active
-
2006
- 2006-11-23 AT AT06831163T patent/ATE548030T1/de active
- 2006-11-23 NZ NZ566783A patent/NZ566783A/en unknown
- 2006-11-23 ES ES06831163T patent/ES2383760T3/es active Active
- 2006-11-23 JP JP2008542790A patent/JP5674275B2/ja active Active
- 2006-11-23 BR BRPI0619774-4A patent/BRPI0619774B1/pt active IP Right Grant
- 2006-11-23 CN CNA2006800453522A patent/CN101321520A/zh active Pending
- 2006-11-23 PL PL06831163T patent/PL1954251T3/pl unknown
- 2006-11-23 RS RS20120229A patent/RS52308B/en unknown
- 2006-11-23 US US12/085,501 patent/US8834923B2/en active Active
- 2006-11-23 DK DK06831163.8T patent/DK1954251T3/da active
- 2006-11-23 CA CA2632547A patent/CA2632547C/fr active Active
- 2006-11-23 SI SI200631341T patent/SI1954251T1/sl unknown
- 2006-11-23 WO PCT/FR2006/002577 patent/WO2007063200A1/fr active Application Filing
- 2006-11-23 UA UAA200808585A patent/UA93530C2/ru unknown
- 2006-11-23 AU AU2006319077A patent/AU2006319077B2/en active Active
- 2006-11-23 EP EP06831163A patent/EP1954251B1/fr active Active
- 2006-11-23 RU RU2008126728/15A patent/RU2414211C2/ru active
- 2006-11-23 PT PT06831163T patent/PT1954251E/pt unknown
- 2006-11-23 KR KR1020087008548A patent/KR101332744B1/ko active IP Right Grant
- 2006-11-30 TW TW095144284A patent/TWI374035B/zh active
- 2006-12-01 AR ARP060105306A patent/AR057212A1/es not_active Application Discontinuation
-
2008
- 2008-02-28 ZA ZA200801896A patent/ZA200801896B/xx unknown
- 2008-03-07 MA MA30732A patent/MA29770B1/fr unknown
- 2008-04-02 TN TNP2008000152A patent/TNSN08152A1/fr unknown
- 2008-04-29 NO NO20082047A patent/NO339720B1/no unknown
- 2008-05-27 IL IL191758A patent/IL191758A/en active IP Right Grant
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Legal Events
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| FC | Refusal |